메뉴 건너뛰기




Volumn 16, Issue 8, 2006, Pages 693-701

The role of Toll-like receptors in non-infectious lung injury

Author keywords

Apoptosis; Hyaluronan; Inflammation; Lung injury; Toll like receptors

Indexed keywords

HERMES ANTIGEN; HYALURONIC ACID; ISOPROTEIN; LIGAND; TOLL LIKE RECEPTOR;

EID: 33747483267     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/sj.cr.7310085     Document Type: Review
Times cited : (133)

References (99)
  • 1
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature 2000; 406:782-787.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 2
    • 0042405132 scopus 로고    scopus 로고
    • Recognition of microbial infection by Toll-like receptors
    • Kopp E, Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 2003; 15:396-401.
    • (2003) Curr Opin Immunol , vol.15 , pp. 396-401
    • Kopp, E.1    Medzhitov, R.2
  • 3
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 1989; 54(Part 1):1-13.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , Issue.1 PART , pp. 1-13
    • Janeway Jr., C.A.1
  • 4
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388:394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 5
  • 6
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5:987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 7
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 8
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
    • Takeuchi O, Hoshino K, Kawai T, et al. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 1999; 11:443-451.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3
  • 10
    • 0032701642 scopus 로고    scopus 로고
    • Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium
    • Frantz S, Kobzik L, Kim YD, et al. Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. J Clin Invest 1999; 104:271-280.
    • (1999) J Clin Invest , vol.104 , pp. 271-280
    • Frantz, S.1    Kobzik, L.2    Kim, Y.D.3
  • 11
    • 30744462300 scopus 로고    scopus 로고
    • Regulation of lung injury and repair by Toll-like receptors and hyaluronan
    • Jiang D, Liang J, Fan J, et al. Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med 2005; 11:1173-1179.
    • (2005) Nat Med , vol.11 , pp. 1173-1179
    • Jiang, D.1    Liang, J.2    Fan, J.3
  • 12
    • 0031774181 scopus 로고    scopus 로고
    • Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
    • Kirschning CJ, Wesche H, Merrill Ayres T, Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 1998; 188:2091-2097.
    • (1998) J Exp Med , vol.188 , pp. 2091-2097
    • Kirschning, C.J.1    Wesche, H.2    Merrill Ayres, T.3    Rothe, M.4
  • 13
    • 0032541661 scopus 로고    scopus 로고
    • Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
    • Yang RB, Mark MR, Gray A, et al. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 1998; 395:284-288.
    • (1998) Nature , vol.395 , pp. 284-288
    • Yang, R.B.1    Mark, M.R.2    Gray, A.3
  • 14
    • 0033592748 scopus 로고    scopus 로고
    • The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
    • Underhill DM, Ozinsky A, Hajjar AM, et al. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999; 401:811-815.
    • (1999) Nature , vol.401 , pp. 811-815
    • Underhill, D.M.1    Ozinsky, A.2    Hajjar, A.M.3
  • 15
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282:2085-2088.
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 16
    • 0037026527 scopus 로고    scopus 로고
    • Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
    • Bochkov VN, Kadl A, Huber J, et al. Protective role of phospholipid oxidation products in endotoxin-induced tissue damage. Nature 2002; 419:77-81.
    • (2002) Nature , vol.419 , pp. 77-81
    • Bochkov, V.N.1    Kadl, A.2    Huber, J.3
  • 17
    • 18644376284 scopus 로고    scopus 로고
    • IRF3 mediates a TLR3/TLR4-specific antiviral gene program
    • Doyle S, Vaidya S, O'Connell R, et al. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 2002; 17:251-263.
    • (2002) Immunity , vol.17 , pp. 251-263
    • Doyle, S.1    Vaidya, S.2    O'Connell, R.3
  • 18
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001; 413:732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 19
    • 11144273976 scopus 로고    scopus 로고
    • Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
    • Wang T, Town T, Alexopoulou L, et al. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 2004; 10:1366-1373.
    • (2004) Nat Med , vol.10 , pp. 1366-1373
    • Wang, T.1    Town, T.2    Alexopoulou, L.3
  • 20
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, et al. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004; 303:1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3
  • 21
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408:740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3
  • 22
    • 0032133278 scopus 로고    scopus 로고
    • MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
    • Medzhitov R, Preston-Hurlburt P, Kopp E, et al. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Molecular Cell 1998; 2:253-258.
    • (1998) Molecular Cell , vol.2 , pp. 253-258
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Kopp, E.3
  • 23
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- And IL-18-mediated function
    • Adachi O, Kawai T, Takeda K, et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 1998; 9:143-150.
    • (1998) Immunity , vol.9 , pp. 143-150
    • Adachi, O.1    Kawai, T.2    Takeda, K.3
  • 24
    • 0030694108 scopus 로고    scopus 로고
    • IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
    • Muzio M, Ni J, Feng P, Dixit VM. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 1997; 278:1612-1615.
    • (1997) Science , vol.278 , pp. 1612-1615
    • Muzio, M.1    Ni, J.2    Feng, P.3    Dixit, V.M.4
  • 25
    • 0030662372 scopus 로고    scopus 로고
    • Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein
    • Huang J, Gao X, Li S, Cao Z. Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. Proc Natl Acad Sci USA 1997; 94:12829-12832.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12829-12832
    • Huang, J.1    Gao, X.2    Li, S.3    Cao, Z.4
  • 26
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin-1 receptor
    • Cao Z, Henzel WJ, Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science 1996; 271:1128-1131.
    • (1996) Science , vol.271 , pp. 1128-1131
    • Cao, Z.1    Henzel, W.J.2    Gao, X.3
  • 27
    • 18444390259 scopus 로고    scopus 로고
    • Distinct molecular mechanism for initiating TRAF6 signalling
    • Ye H, Arron JR, Lamothe B, et al. Distinct molecular mechanism for initiating TRAF6 signalling. Nature 2002; 418:443-447.
    • (2002) Nature , vol.418 , pp. 443-447
    • Ye, H.1    Arron, J.R.2    Lamothe, B.3
  • 28
    • 0029940355 scopus 로고    scopus 로고
    • TAB1: An activator of the TAK1 MAPKKK in TGF-beta signal transduction
    • Shibuya H, Yamaguchi K, Shirakabe K, et al. TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science 1996; 272:1179-1182.
    • (1996) Science , vol.272 , pp. 1179-1182
    • Shibuya, H.1    Yamaguchi, K.2    Shirakabe, K.3
  • 29
    • 0033634977 scopus 로고    scopus 로고
    • TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
    • Takaesu G, Kishida S, Hiyama A, et al. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell 2000; 5:649-658.
    • (2000) Mol Cell , vol.5 , pp. 649-658
    • Takaesu, G.1    Kishida, S.2    Hiyama, A.3
  • 30
    • 0033580466 scopus 로고    scopus 로고
    • The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
    • Ninomiya-Tsuji J, Kishimoto K, Hiyama A, et al. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 1999; 398:252-256.
    • (1999) Nature , vol.398 , pp. 252-256
    • Ninomiya-Tsuji, J.1    Kishimoto, K.2    Hiyama, A.3
  • 31
    • 0037153130 scopus 로고    scopus 로고
    • The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    • Horng T, Barton GM, Flavell RA, Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002; 420:329-333.
    • (2002) Nature , vol.420 , pp. 329-333
    • Horng, T.1    Barton, G.M.2    Flavell, R.A.3    Medzhitov, R.4
  • 32
    • 0035817925 scopus 로고    scopus 로고
    • Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
    • Fitzgerald KA, Palsson-McDermott EM, Bowie AG, et al. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001; 413:78-83.
    • (2001) Nature , vol.413 , pp. 78-83
    • Fitzgerald, K.A.1    Palsson-McDermott, E.M.2    Bowie, A.G.3
  • 33
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • Yamamoto M, Sato S, Hemmi H, et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003; 301:640-643.
    • (2003) Science , vol.301 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3
  • 34
    • 0242624622 scopus 로고    scopus 로고
    • TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
    • Yamamoto M, Sato S, Hemmi H, et al. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 2003; 4:1144-1150.
    • (2003) Nat Immunol , vol.4 , pp. 1144-1150
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3
  • 35
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
    • Ohashi K, Burkart V, Flohe S, Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000; 164:558-561.
    • (2000) J Immunol , vol.164 , pp. 558-561
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 36
    • 24744442576 scopus 로고    scopus 로고
    • Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway
    • Cohen-Sfady M, Nussbaum G, Pevsner-Fischer M, et al. Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway. J Immunol 2005; 175:3594-3602.
    • (2005) J Immunol , vol.175 , pp. 3594-3602
    • Cohen-Sfady, M.1    Nussbaum, G.2    Pevsner-Fischer, M.3
  • 37
    • 0035903158 scopus 로고    scopus 로고
    • Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells
    • Vabulas RM, Ahmad-Nejad P, da Costa C, et al. Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J Biol Chem 2001; 276:31332-31339.
    • (2001) J Biol Chem , vol.276 , pp. 31332-31339
    • Vabulas, R.M.1    Ahmad-Nejad, P.2    Da Costa, C.3
  • 38
    • 1542380035 scopus 로고    scopus 로고
    • Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
    • Park JS, Svetkauskaite D, He Q, et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004; 279:7370-7377.
    • (2004) J Biol Chem , vol.279 , pp. 7370-7377
    • Park, J.S.1    Svetkauskaite, D.2    He, Q.3
  • 39
    • 0036829687 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2
    • Biragyn A, Ruffini PA, Leifer CA, et al. Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science 2002; 298:1025-1029.
    • (2002) Science , vol.298 , pp. 1025-1029
    • Biragyn, A.1    Ruffini, P.A.2    Leifer, C.A.3
  • 40
    • 0037097672 scopus 로고    scopus 로고
    • Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
    • Guillot L, Balloy V, McCormack FX, et al. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J Immunol 2002; 168:5989-5992.
    • (2002) J Immunol , vol.168 , pp. 5989-5992
    • Guillot, L.1    Balloy, V.2    McCormack, F.X.3
  • 41
    • 26844467349 scopus 로고    scopus 로고
    • Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
    • Barrat FJ, Meeker T, Gregorio J, et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med 2005; 202:1131-1139.
    • (2005) J Exp Med , vol.202 , pp. 1131-1139
    • Barrat, F.J.1    Meeker, T.2    Gregorio, J.3
  • 42
    • 2342428467 scopus 로고    scopus 로고
    • Hyaluronan fragments stimulate endothelial recognition of injury through TLR4
    • Taylor KR, Trowbridge JM, Rudisill JA, et al. Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. J Biol Chem 2004; 279:17079-17084.
    • (2004) J Biol Chem , vol.279 , pp. 17079-17084
    • Taylor, K.R.1    Trowbridge, J.M.2    Rudisill, J.A.3
  • 43
    • 0037033364 scopus 로고    scopus 로고
    • Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4
    • Termeer C, Benedix F, Sleeman J, et al. Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 2002; 195:99-111.
    • (2002) J Exp Med , vol.195 , pp. 99-111
    • Termeer, C.1    Benedix, F.2    Sleeman, J.3
  • 44
    • 0037094084 scopus 로고    scopus 로고
    • Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
    • Johnson GB, Brunn GJ, Kodaira Y, Platt JL. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol 2002; 168:5233-5239.
    • (2002) J Immunol , vol.168 , pp. 5233-5239
    • Johnson, G.B.1    Brunn, G.J.2    Kodaira, Y.3    Platt, J.L.4
  • 45
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • Tsan MF, Gao B. Endogenous ligands of Toll-like receptors. J Leukocyte Biol 2004.
    • (2004) J Leukocyte Biol
    • Tsan, M.F.1    Gao, B.2
  • 46
    • 0034662239 scopus 로고    scopus 로고
    • Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
    • Hirschfeld M, Ma Y, Weis JH, et al. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 2000; 165:618-622.
    • (2000) J Immunol , vol.165 , pp. 618-622
    • Hirschfeld, M.1    Ma, Y.2    Weis, J.H.3
  • 47
    • 0037928705 scopus 로고    scopus 로고
    • Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages
    • Gao B, Tsan MF. Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages. J Biol Chem 2003; 278:22523-22529.
    • (2003) J Biol Chem , vol.278 , pp. 22523-22529
    • Gao, B.1    Tsan, M.F.2
  • 48
    • 0037414787 scopus 로고    scopus 로고
    • Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages
    • Gao B, Tsan MF. Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages. J Biol Chem 2003; 278:174-179.
    • (2003) J Biol Chem , vol.278 , pp. 174-179
    • Gao, B.1    Tsan, M.F.2
  • 49
    • 0037177833 scopus 로고    scopus 로고
    • HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway
    • Vabulas RM, Ahmad-Nejad P, Ghose S, et al. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J Biol Chem 2002; 277:15107-15112.
    • (2002) J Biol Chem , vol.277 , pp. 15107-15112
    • Vabulas, R.M.1    Ahmad-Nejad, P.2    Ghose, S.3
  • 50
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
    • Asea A, Rehli M, Kabingu E, et al. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 2002; 277:15028-15034.
    • (2002) J Biol Chem , vol.277 , pp. 15028-15034
    • Asea, A.1    Rehli, M.2    Kabingu, E.3
  • 51
    • 23644456849 scopus 로고    scopus 로고
    • The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
    • Schaefer L, Babelova A, Kiss E, et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest 2005; 115:2223-2233.
    • (2005) J Clin Invest , vol.115 , pp. 2223-2233
    • Schaefer, L.1    Babelova, A.2    Kiss, E.3
  • 52
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product
    • Hoshino K, Takeuchi O, Kawai T, et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 1999; 162:3749-3752.
    • (1999) J Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3
  • 53
    • 0035895913 scopus 로고    scopus 로고
    • Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes
    • Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem 2001; 276:5197-5203.
    • (2001) J Biol Chem , vol.276 , pp. 5197-5203
    • Frantz, S.1    Kelly, R.A.2    Bourcier, T.3
  • 54
    • 23744442371 scopus 로고    scopus 로고
    • TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children
    • Berdeli A, Celik HA, Ozyurek R, et al. TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children. J Mol Med 2005; 83:535-541.
    • (2005) J Mol Med , vol.83 , pp. 535-541
    • Berdeli, A.1    Celik, H.A.2    Ozyurek, R.3
  • 55
    • 21544462582 scopus 로고    scopus 로고
    • A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis
    • Hamann L, Gomma A, Schroder NW, et al. A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis. J Mol Med 2005; 83:478-485.
    • (2005) J Mol Med , vol.83 , pp. 478-485
    • Hamann, L.1    Gomma, A.2    Schroder, N.W.3
  • 56
    • 0037069791 scopus 로고    scopus 로고
    • Toll-like receptor 4 polymorphisms and atherogenesis
    • author reply 1978-1980
    • Cooke GS, Segal S, Hill AV. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 2002; 347:1978-1980; author reply 1978-1980.
    • (2002) N Engl J Med , vol.347 , pp. 1978-1980
    • Cooke, G.S.1    Segal, S.2    Hill, A.V.3
  • 57
    • 0347949501 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) 4 polymorphisms and COPD
    • Sabroe I, Whyte MK, Wilson AG, et al. Toll-like receptor (TLR) 4 polymorphisms and COPD. Thorax 2004; 59:81.
    • (2004) Thorax , vol.59 , pp. 81
    • Sabroe, I.1    Whyte, M.K.2    Wilson, A.G.3
  • 58
    • 3242728901 scopus 로고    scopus 로고
    • Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
    • Bjorkbacka H, Kunjathoor VV, Moore KJ, et al. Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Nat Med 2004; 10:416-421.
    • (2004) Nat Med , vol.10 , pp. 416-421
    • Bjorkbacka, H.1    Kunjathoor, V.V.2    Moore, K.J.3
  • 59
    • 0037130195 scopus 로고    scopus 로고
    • Toll-like receptor 4 polymorphisms and atherogenesis
    • Kiechl S, Lorenz E, Reindl M, et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 2002; 347:185-192.
    • (2002) N Engl J Med , vol.347 , pp. 185-192
    • Kiechl, S.1    Lorenz, E.2    Reindl, M.3
  • 60
    • 33645858755 scopus 로고    scopus 로고
    • The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles
    • Inoue K, Takano H, Yanagisawa R, et al. The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles. Arch Toxicol 2006; 80:275-279.
    • (2006) Arch Toxicol , vol.80 , pp. 275-279
    • Inoue, K.1    Takano, H.2    Yanagisawa, R.3
  • 61
    • 0034029244 scopus 로고    scopus 로고
    • Genetic susceptibility to ozone-induced lung hyperpermeability: Role of toll-like receptor 4
    • Kleeberger SR, Reddy S, Zhang LY, Jedlicka AE. Genetic susceptibility to ozone-induced lung hyperpermeability: role of toll-like receptor 4. Am J Respir Cell Mol Biol 2000; 22:620-627.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 620-627
    • Kleeberger, S.R.1    Reddy, S.2    Zhang, L.Y.3    Jedlicka, A.E.4
  • 62
    • 4043170040 scopus 로고    scopus 로고
    • Inhibition of experimental asthma by indoleamine 2,3-dioxygenase
    • Hayashi T, Beck L, Rossetto C, et al. Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J Clin Invest 2004; 114:270-279.
    • (2004) J Clin Invest , vol.114 , pp. 270-279
    • Hayashi, T.1    Beck, L.2    Rossetto, C.3
  • 63
    • 33745483812 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages
    • Karimi K, Sarir H, Mortaz E, et al. Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages. Respir Res 2006; 7:66.
    • (2006) Respir Res , vol.7 , pp. 66
    • Karimi, K.1    Sarir, H.2    Mortaz, E.3
  • 64
    • 33646508108 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease
    • Pons J, Sauleda J, Regueiro V, et al. Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease. Respir Res 2006; 7:64.
    • (2006) Respir Res , vol.7 , pp. 64
    • Pons, J.1    Sauleda, J.2    Regueiro, V.3
  • 65
    • 26244461463 scopus 로고    scopus 로고
    • Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients
    • Droemann D, Goldmann T, Tiedje T, et al. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients. Respir Res 2005; 6:68.
    • (2005) Respir Res , vol.6 , pp. 68
    • Droemann, D.1    Goldmann, T.2    Tiedje, T.3
  • 67
    • 33646562230 scopus 로고    scopus 로고
    • Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: Role in hemorrhage-primed lung inflammation
    • Fan J, Li Y, Vodovotz Y, et al. Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation. Am J Physiol Lung Cell Mol Physiol 2006; 290: L738-L746.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Fan, J.1    Li, Y.2    Vodovotz, Y.3
  • 68
    • 26844536104 scopus 로고    scopus 로고
    • Cutting edge: TLR4 deficiency confers susceptibility to lethal oxidant lung injury
    • Zhang X, Shan P, Qureshi S, et al. Cutting edge: TLR4 deficiency confers susceptibility to lethal oxidant lung injury. J Immunol 2005; 175:4834-4838.
    • (2005) J Immunol , vol.175 , pp. 4834-4838
    • Zhang, X.1    Shan, P.2    Qureshi, S.3
  • 70
    • 0030820092 scopus 로고    scopus 로고
    • Hyaluronan: Its nature, distribution, functions and turnover
    • Fraser JR, Laurent TC, Laurent UB. Hyaluronan: its nature, distribution, functions and turnover. J Intern Med 1997; 242:27-33.
    • (1997) J Intern Med , vol.242 , pp. 27-33
    • Fraser, J.R.1    Laurent, T.C.2    Laurent, U.B.3
  • 71
    • 0037023364 scopus 로고    scopus 로고
    • Resolution of lung inflammation by CD44
    • Teder P, Vandivier RW, Jiang D, et al. Resolution of lung inflammation by CD44. Science 2002; 296:155-158.
    • (2002) Science , vol.296 , pp. 155-158
    • Teder, P.1    Vandivier, R.W.2    Jiang, D.3
  • 73
    • 0021834944 scopus 로고
    • Angiogenesis induced by degradation products of hyaluronic acid
    • West DC, Hampson IN, Arnold F, Kumar S. Angiogenesis induced by degradation products of hyaluronic acid. Science 1985; 228:1324-1326.
    • (1985) Science , vol.228 , pp. 1324-1326
    • West, D.C.1    Hampson, I.N.2    Arnold, F.3    Kumar, S.4
  • 74
    • 0024367374 scopus 로고
    • Hyaluronan and angiogenesis
    • West DC, Kumar S. Hyaluronan and angiogenesis. Ciba Found Symp 1989; 143:187-201; discussion 201-187, 281-185.
    • (1989) Ciba Found Symp , vol.143 , pp. 187-201
    • West, D.C.1    Kumar, S.2
  • 75
    • 0032521288 scopus 로고    scopus 로고
    • Regulation of hyaluronan-induced chemokine gene expression by IL-10 and IFN-gamma in mouse macrophages
    • Horton MR, Burdick MD, Strieter RM, et al. Regulation of hyaluronan-induced chemokine gene expression by IL-10 and IFN-gamma in mouse macrophages. J Immunol 1998; 160:3023-3030.
    • (1998) J Immunol , vol.160 , pp. 3023-3030
    • Horton, M.R.1    Burdick, M.D.2    Strieter, R.M.3
  • 76
    • 0029808003 scopus 로고    scopus 로고
    • Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. the role of HA size and CD44
    • McKee CM, Penno MB, Cowman M, et al. Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44. J Clin Invest 1996; 98:2403-2413.
    • (1996) J Clin Invest , vol.98 , pp. 2403-2413
    • McKee, C.M.1    Penno, M.B.2    Cowman, M.3
  • 77
    • 0029952227 scopus 로고    scopus 로고
    • Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages
    • Noble PW, McKee CM, Cowman M, Shin HS. Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages. J Exp Med 1996; 183:2373-2378.
    • (1996) J Exp Med , vol.183 , pp. 2373-2378
    • Noble, P.W.1    McKee, C.M.2    Cowman, M.3    Shin, H.S.4
  • 78
    • 0033788442 scopus 로고    scopus 로고
    • Activation and transforming growth factor-beta production in eosinophils by hyaluronan
    • Ohkawara Y, Tamura G, Iwasaki T, et al. Activation and transforming growth factor-beta production in eosinophils by hyaluronan. Am J Respir Cell Mol Biol 2000; 23:444-451.
    • (2000) Am J Respir Cell Mol Biol , vol.23 , pp. 444-451
    • Ohkawara, Y.1    Tamura, G.2    Iwasaki, T.3
  • 79
    • 0034651567 scopus 로고    scopus 로고
    • Ras, protein kinase C zeta, and I kappa B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kappa B by hyaluronic acid fragments in T-24 carcinoma cells
    • Fitzgerald KA, Bowie AG, Skeffington BS, O'Neill LA. Ras, protein kinase C zeta, and I kappa B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kappa B by hyaluronic acid fragments in T-24 carcinoma cells. Journal of Immunology 2000; 164:2053-2063.
    • (2000) Journal of Immunology , vol.164 , pp. 2053-2063
    • Fitzgerald, K.A.1    Bowie, A.G.2    Skeffington, B.S.3    O'Neill, L.A.4
  • 80
    • 0034689057 scopus 로고    scopus 로고
    • Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth
    • published erratum appears in J Cell Biol 2000 Apr 3;149(1):following 236
    • Oliferenko S, Kaverina I, Small JV, Huber LA. Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth [published erratum appears in J Cell Biol 2000 Apr 3;149(1):following 236]. Journal of Cell Biology 2000; 148:1159-1164.
    • (2000) Journal of Cell Biology , vol.148 , pp. 1159-1164
    • Oliferenko, S.1    Kaverina, I.2    Small, J.V.3    Huber, L.A.4
  • 81
    • 0034663808 scopus 로고    scopus 로고
    • Oligosaccharides of hyaluronan are potent activators of dendritic cells
    • Termeer CC, Hennies J, Voith U, et al. Oligosaccharides of hyaluronan are potent activators of dendritic cells. Journal of Immunology 2000; 165:1863-1870.
    • (2000) Journal of Immunology , vol.165 , pp. 1863-1870
    • Termeer, C.C.1    Hennies, J.2    Voith, U.3
  • 82
    • 0025282411 scopus 로고
    • CD44 is the principal cell surface receptor for hyaluronate
    • Aruffo A, Stamenkovic I, Melnick M, et al. CD44 is the principal cell surface receptor for hyaluronate. Cell 1990; 61:1303-1313.
    • (1990) Cell , vol.61 , pp. 1303-1313
    • Aruffo, A.1    Stamenkovic, I.2    Melnick, M.3
  • 83
  • 84
    • 0037780985 scopus 로고    scopus 로고
    • The liberation of CD44
    • Cichy J, Pure E. The liberation of CD44. J Cell Biol 2003; 161:839-843.
    • (2003) J Cell Biol , vol.161 , pp. 839-843
    • Cichy, J.1    Pure, E.2
  • 85
    • 0033806427 scopus 로고    scopus 로고
    • Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking
    • Mummert ME, Mohamadzadeh M, Mummert DI, et al. Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking. J Exp Med 2000; 192:769-779.
    • (2000) J Exp Med , vol.192 , pp. 769-779
    • Mummert, M.E.1    Mohamadzadeh, M.2    Mummert, D.I.3
  • 86
    • 18244374740 scopus 로고    scopus 로고
    • T cell-induced hyaluronan production by epithelial cells regulates inflammation
    • Jameson JM, Cauvi G, Sharp LL, et al. gammadelta T cell-induced hyaluronan production by epithelial cells regulates inflammation. J Exp Med 2005; 201:1269-1279.
    • (2005) J Exp Med , vol.201 , pp. 1269-1279
    • Jameson, J.M.1    Cauvi, G.2    Sharp, L.L.3    Gammadelta, E.A.4
  • 87
    • 0030796519 scopus 로고    scopus 로고
    • CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity
    • Schmits R, Filmus J, Gerwin N, et al. CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity. Blood 1997; 90:2217-2233.
    • (1997) Blood , vol.90 , pp. 2217-2233
    • Schmits, R.1    Filmus, J.2    Gerwin, N.3
  • 88
    • 0031225365 scopus 로고    scopus 로고
    • Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages
    • Hodge-Dufour J, Noble PW, Horton MR, et al. Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages. Journal of Immunology 1997; 159:2492-2500.
    • (1997) Journal of Immunology , vol.159 , pp. 2492-2500
    • Hodge-Dufour, J.1    Noble, P.W.2    Horton, M.R.3
  • 89
    • 0033179160 scopus 로고    scopus 로고
    • Hyaluronate-enhanced hematopoiesis: Two different receptors trigger the release of interleukin-1beta and interleukin-6 from bone marrow macrophages
    • Khaldoyanidi S, Moll J, Karakhanova S, et al. Hyaluronate-enhanced hematopoiesis: two different receptors trigger the release of interleukin-1beta and interleukin-6 from bone marrow macrophages. Blood 1999; 94:940-949.
    • (1999) Blood , vol.94 , pp. 940-949
    • Khaldoyanidi, S.1    Moll, J.2    Karakhanova, S.3
  • 90
    • 0033565407 scopus 로고    scopus 로고
    • Signaling events induced by lipopolysaccharide-activated toll-like receptor 2
    • Yang RB, Mark MR, Gurney AL, Godowski PJ. Signaling events induced by lipopolysaccharide-activated toll-like receptor 2. Journal of Immunology 1999; 163:639-643.
    • (1999) Journal of Immunology , vol.163 , pp. 639-643
    • Yang, R.B.1    Mark, M.R.2    Gurney, A.L.3    Godowski, P.J.4
  • 91
    • 0037108377 scopus 로고    scopus 로고
    • Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation
    • Mummert ME, Mummert D, Edelbaum D, et al. Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation. J Immunol 2002; 169:4322-4331.
    • (2002) J Immunol , vol.169 , pp. 4322-4331
    • Mummert, M.E.1    Mummert, D.2    Edelbaum, D.3
  • 92
    • 0031755720 scopus 로고    scopus 로고
    • Hyaluronan induces monocyte chemoattractant protein-1 expression in renal tubular epithelial cells
    • Beck-Schimmer B, Oertli B, Pasch T, Wuthrich RP. Hyaluronan induces monocyte chemoattractant protein-1 expression in renal tubular epithelial cells. J Am Soc Nephrol 1998; 9:2283-2290.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 2283-2290
    • Beck-Schimmer, B.1    Oertli, B.2    Pasch, T.3    Wuthrich, R.P.4
  • 93
    • 0032193210 scopus 로고    scopus 로고
    • Mechanisms of hyaluronan-induced up-regulation of ICAM-1 and VCAM-1 expression by murine kidney tubular epithelial cells: Hyaluronan triggers cell adhesion molecule expression through a mechanism involving activation of nuclear factor-kappa B and activating protein-1
    • Oertli B, Beck-Schimmer B, Fan X, Wuthrich RP. Mechanisms of hyaluronan-induced up-regulation of ICAM-1 and VCAM-1 expression by murine kidney tubular epithelial cells: hyaluronan triggers cell adhesion molecule expression through a mechanism involving activation of nuclear factor-kappa B and activating protein-1. J Immunol 1998; 161:3431-3437.
    • (1998) J Immunol , vol.161 , pp. 3431-3437
    • Oertli, B.1    Beck-Schimmer, B.2    Fan, X.3    Wuthrich, R.P.4
  • 94
    • 1342322656 scopus 로고    scopus 로고
    • Hyaluronan and proximal tubular cell migration
    • Ito T, Williams JD, Al-Assaf S, et al. Hyaluronan and proximal tubular cell migration. Kidney Int 2004; 65:823-833.
    • (2004) Kidney Int , vol.65 , pp. 823-833
    • Ito, T.1    Williams, J.D.2    Al-Assaf, S.3
  • 95
    • 0347634337 scopus 로고    scopus 로고
    • Low molecular weight hyaluronan from stretched lung enhances interleukin-8 expression
    • Mascarenhas MM, Day RM, Ochoa CD, et al. Low molecular weight hyaluronan from stretched lung enhances interleukin-8 expression. Am J Respir Cell Mol Biol 2004; 30:51-60.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 51-60
    • Mascarenhas, M.M.1    Day, R.M.2    Ochoa, C.D.3
  • 96
    • 17844386319 scopus 로고    scopus 로고
    • IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
    • Lawrence T, Bebien M, Liu GY, et al. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 2005; 434:1138-1143.
    • (2005) Nature , vol.434 , pp. 1138-1143
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3
  • 97
    • 0038587747 scopus 로고    scopus 로고
    • The two faces of IKK and NF-kappaB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
    • Chen LW, Egan L, Li ZW, et al. The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 2003; 9:575-581.
    • (2003) Nat Med , vol.9 , pp. 575-581
    • Chen, L.W.1    Egan, L.2    Li, Z.W.3
  • 98
    • 30744459604 scopus 로고    scopus 로고
    • TLRs play good cop, bad cop in the lung
    • O'Neill LA. TLRs play good cop, bad cop in the lung. Nat Med 2005; 11:1161-1162.
    • (2005) Nat Med , vol.11 , pp. 1161-1162
    • O'Neill, L.A.1
  • 99
    • 4444292595 scopus 로고    scopus 로고
    • Activation of airway epithelial cells by toll-like receptor agonists
    • Sha Q, Truong-Tran AQ, Plitt JR, et al. Activation of airway epithelial cells by toll-like receptor agonists. Am J Respir Cell Mol Biol 2004; 31:358-364.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 358-364
    • Sha, Q.1    Truong-Tran, A.Q.2    Plitt, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.