Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: Role in hemorrhage-primed lung inflammation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 4, 2006, Pages

  Fan, Jie ^a,b   Li, Yuehua ^a   Vodovotz, Yoram ^a   Billiar, Timothy R ^a   Wilson, Mark A ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acute lung injury; Innate immunity; Lipopolysaccharide; Peptidoglycan; Toll like receptor

Indexed keywords

LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; MACROPHAGE MIGRATION INHIBITION FACTOR; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEMORRHAGIC SHOCK; IN VITRO STUDY; LEUKOCYTE ACTIVATION; LEUKOCYTE MIGRATION; LUNG ALVEOLUS; LUNG ALVEOLUS MACROPHAGE; LUNG HEMORRHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHILIA; NONHUMAN; PNEUMONIA; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; RESUSCITATION; UPREGULATION;

ANIMALS; CYTOKINES; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; NEUTROPHIL ACTIVATION; NEUTROPHIL INFILTRATION; PNEUMONIA; RESUSCITATION; SHOCK, HEMORRHAGIC; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 33646562230     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00280.2005     Document Type: Article

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