Hyaluronan fragments activate an NF-κB/I-κBα autoregulatory loop in murine macrophages

Journal of Experimental Medicine

Volumn 183, Issue 5, 1996, Pages 2373-2378

  Noble, Paul W ^a   McKee, Charlotte M ^a   Cowman, Mary ^b   Shin, Hyun S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b POLYTECHNIC UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLYCOSAMINOGLYCAN; GROWTH FACTOR; HYALURONIC ACID; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HOST RESISTANCE; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; TISSUE REPAIR; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CONSENSUS SEQUENCE; CYCLOHEXIMIDE; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; HOMEOSTASIS; HUMANS; HYALURONIC ACID; I-KAPPA B PROTEINS; IMMUNOGLOBULIN KAPPA-CHAINS; KINETICS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; OLIGOPEPTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC;

EID: 0029952227     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.5.2373     Document Type: Article

References (32)

1. Nathan, C. 1987. Secretory products of macrophages. J. Clin. Invest. 79:319-322.
2. Leibovitch, S., and R. Ross. 1975. The role of the macrophage in wound repair: a study of hydrocortisone and antimacrophage serum. Am. J. Pathol. 78:71-81.
3. Yanni, G., A. Whelan, C. Feighery, and B. Bresnihan. 1994. Synovial tissue macrophages and joint erosion in rheumatoid arthritis. Ann. Rheum. Dis. 53:39-44.
4. Bitterman, P., S. Adelberg, and R. Crystal. 1983. Mechanisms of pulmonary fibrosis: Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders. J. Clin. Invest. 72:1801-1900.
5. Manthey, C., and S. Vogel. 1994. Interactions of lipopolysaccharide with macrophages. Immunol. Ser. 60:63-81.
6. Piquet, P., M. Collart, G. Grau, Y. Kapanci, and P. Vassalli. 1989. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopachy and fibrosis. J. Exp. Med. 170:655-683.
7. Carre, P., R. Mortenson, T. King, P. Noble, C. Sable, and D. Riches. 1991. Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for recruitment and activation of neutrophils in lung fibrosis. J. Clin. Invest. 88:1802-1810.
8. Standiford, T., M. Rolfe, S. Kunkel, J. Lynch, M. Burdick, A. Gilbert, M. Orringer, R. Whyte, and R. Strieter. 1993. Macrophage inflammatory protein-1 alpha expression in interstitial lung disease. J. Immunol. 151:2852-2863.
9. Newman, S., and M. Tucci. 1990. Regulation of human monocyte/macrophage function by extracellular matrix. J. Clin. Invest. 86:703-714.
10. Nathan, C., C. Farber, E. Sanchez, L. Kabbash, A. Asch, J. Gailit, and S. Wright. 1989. Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins. J. Cell Biol. 109: 1341-1349.
11. Lesley, J., R. Hyman, and P. Kincade. 1993. CD44 and its interaction with extracellular matrix. Adv. Immunol. 54:271-335.
12. Poole, A., and P. Dieppe. 1994. Biological markers in rheumatoid arthritis. Semin. Arthritis Rheum. 23S:17-31.
13. West, D., I. Hampson, F. Arnold, and S. Kumar. 1985. Angiogenesis induced by degradation products of hyaluronic acid. Science (Wash. DC). 228:1324-1326.
14. Forrester, J., and E. Balazs. 1980. Inhibition of phagocytosis by high molecular weight hyaluronate. Immunology. 40:435-446.
15. Grilli, M., J.-S. Chiu, and M. Lenardo. 1993. NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143:1-62.
16. Noble, P., F. Lake, P. Henson, and D. Riches. 1993. Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-α-dependent mechanism in murine macrophages. J. Clin. Invest. 91:2368-2377.
17. Cogswell, J., M. Godlevski, G. Wisely, W. Clay, L. Leesnitzer, J. Ways, and J. Gray. 1994. NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-hke site. J. Immunol. 153:712-723.
18. Shakhov, A., M. Collart, P. Vassalli, S. Nedospasov, and C. Jongeneel. 1990. κB-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factorα gene in primary macrophages. J. Exp. Med. 171:35-47.
19. Mbawuike, I., and H. Herscowitz. 1989. MH-S, a murine alveolar macrophage cell line: morphological, cytochemical, and functional characteristics. J. Lenk. Biol. 46:119-127.
20. Yannariello-Brown, J., S. Frost, and P. Weigel. 1992. Identification of the Ca(2+)-independent endocytic hyaluronan receptor in rat liver sinusoidal endothelial cells using a photaffinity cross-linking reagent. J. Biol. Chem. 267:20451-20456.
21. Lee, H., and M. Cowman. 1994. An agarose gel electrophoretic method for analysis of hyaluronan molecular weight distribution. Anal. Biochem. 219:278-287.
22. Shin, H., B.-E. Drysdale, M. Shin, P. Noble, S. Fisher, and W. Paznekas. 1994. Definition of a lipopolysaccharide-responsive element in the 5′-flanking regions of murantes and crg-2. Mol. Cell. Biol. 14:2914-2925.
23. Haskill, S., A. Beg, S. Tompkins, J. Morris, A. Yurochko, A. Sampson-Johannes, K. Mondal, P. Ralph, and A. Baldwin. 1991. Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity. Cell. 65:1281-1289.
24. Andrews, N., and D. Faller. 1991. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19:2499.
25. Sun, S.-C., P.A. Ganchi, D.W. Ballard, and W.C. Greene. 1993. NF-kB controls expression of inhibitor IκBα: evidence for an inducible autoregulatory pathway. Science (Wash. DC). 259:1912-1915.
26. Chiao, P., S. Miyamoto, and I. Verma. 1994. Autoregulation of IκBα activity. Proc. Natl. Acad. Sci. USA. 91:28-32.
27. Brown, K., S. Park, T. Kanno, G. Franzoso, and U. Siebenlist. 1993. Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α. Proc. Natl. Acad. Sci. USA. 90:2532-2536.
28. Wrenshall, L., F. Cerra, R. Singh, and J. Platt. 1995. Heparan sulfate initiates signals in murine macrophages leading to divergent biologic outcomes. J. Immunol. 154:871-880.
29. Lofquist, A., K. Mondal, J. Norris, and S. Haskill. 1995. Transcription-independent turnover of I kappa B alpha during monocyte adherence: implication for a translational component regulating I kappa B/MAD-3 mRNA levels. Mol. Cell Biol. 15:1737-1746.
30. Ohmori, Y., J. Tebo, S. Nedospasov, and T. Hamilton. 1994. KB binding activity in a murine macrophage-like cell line. J. Biol. Chem. 269:17684-17690.
31. Sampson, P., C. Rochester, B. Freundlich, and J. Elias. 1992. Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast-derived hyaluronidase. J. Clin. Invest. 90:1492-1503.
32. Teder, P., O. Nettelbladt, and P. Heldin. 1995. Characterization of the mechanism involved in bleomycin-induced increased hyaluronan production in rat lung. Am. J. Respir. Cell Mol. Biol. 12:181-189.