Toll-like receptor (TLR) 4 polymorphisms and COPD [2]

Thorax

Volumn 59, Issue 1, 2004, Pages 81-

  Sabroe, I ^a,d   Whyte, M K B ^a   Wilson, A G ^a   Dower, S K ^a   Hubbard, R ^b   Hall, I ^c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c QUEEN S MEDICAL CENTRE   (United Kingdom)

^d ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 4;

ADULT; AGED; BRONCHODILATATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE SEVERITY; FORCED EXPIRATORY VOLUME; GENETIC POLYMORPHISM; GENETIC SCREENING; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LETTER; LUNG FUNCTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ADULT; AGED; HOMOZYGOTE; HUMANS; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; POLYMORPHISM, GENETIC; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, CELL SURFACE; SMOKING; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0347949501     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (6)

1. Sabroe I, Read RC, Whyte MKB, et al. Toll-like receptors in health and disease: complex questions remain. J Immunol 2003;171:1630-5.
2. Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nature Genet 2000;25:187-91.
3. Kiechl S, Lorenz E, Reindl M, et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 2002;347:185-92.
4. Lorenz E, Mira JP, Frees KL, et al. Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 2002;162:1028-32.
5. Read RC, Pullin J, Gregory S, et al. A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease. J Infect Dis 2001;184:640-2.
6. Smirnova I, Mann N, Dols A, et al. Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility. Proc Natl Acad Sci USA 2003;100:6075-80.