-
1
-
-
0842281645
-
Cell death. Critical control points
-
Danial N.N., and Korsmeyer S.J. Cell death. Critical control points. Cell 116 (2004) 205-219
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
2
-
-
0021934042
-
Cloning the chromosomal breakpoint of t(14;18) human lymphomas. Clustering around JH on chromosome 14 and near a transcriptional unit on 18
-
Bakhshi A., Jensen J.P., Goldman P., et al. Cloning the chromosomal breakpoint of t(14;18) human lymphomas. Clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 41 (1985) 899-906
-
(1985)
Cell
, vol.41
, pp. 899-906
-
-
Bakhshi, A.1
Jensen, J.P.2
Goldman, P.3
-
3
-
-
0345055662
-
Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18
-
Cleary M.L., and Sklar J. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci U S A 82 (1985) 7439-7443
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 7439-7443
-
-
Cleary, M.L.1
Sklar, J.2
-
4
-
-
0021821903
-
Involvement of the bcl-2 gene in human follicular lymphoma
-
Tsujimoto Y., Cossman J., Jaffe E., et al. Involvement of the bcl-2 gene in human follicular lymphoma. Science 228 (1985) 1440-1443
-
(1985)
Science
, vol.228
, pp. 1440-1443
-
-
Tsujimoto, Y.1
Cossman, J.2
Jaffe, E.3
-
5
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A., Bassik M.C., Walensky L.D., et al. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2 (2002) 183-192
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
-
6
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T., Bouchier-Hayes L., Chipuk J.E., et al. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 17 (2005) 525-535
-
(2005)
Mol Cell
, vol.17
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
-
7
-
-
0035957653
-
Proapoptotic BAX and BAK. a requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., et al. Proapoptotic BAX and BAK. a requisite gateway to mitochondrial dysfunction and death. Science 292 (2001) 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
-
8
-
-
26444558130
-
Pharmacological manipulation of Bcl-2 family members to control cell death
-
Letai A. Pharmacological manipulation of Bcl-2 family members to control cell death. J Clin Invest 115 (2005) 2648-2655
-
(2005)
J Clin Invest
, vol.115
, pp. 2648-2655
-
-
Letai, A.1
-
9
-
-
0036097786
-
Keeping killers on a tight leash. Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath H., and Strasser A. Keeping killers on a tight leash. Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 9 (2002) 505-512
-
(2002)
Cell Death Differ
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
10
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H., Zhu H., Xu C.J., et al. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94 (1998) 491-501
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
-
11
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288 (2000) 1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
-
12
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu J., Zhang L., Hwang P.M., Kinzler K.W., et al. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell 7 (2001) 673-682
-
(2001)
Mol Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
-
13
-
-
0242521470
-
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
-
Luciano F., Jacquel A., Colosetti P., et al. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 22 (2003) 6785-6793
-
(2003)
Oncogene
, vol.22
, pp. 6785-6793
-
-
Luciano, F.1
Jacquel, A.2
Colosetti, P.3
-
14
-
-
0034786019
-
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng E.H., Wei M.C., Weiler S., et al. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell 8 (2001) 705-711
-
(2001)
Mol Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
-
15
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L., Willis S.N., Wei A., et al. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17 (2005) 393-403
-
(2005)
Mol Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
-
16
-
-
0035827622
-
Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax
-
Cuddeback S.M., Yamaguchi H., Komatsu K., et al. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem 276 (2001) 20559-20565
-
(2001)
J Biol Chem
, vol.276
, pp. 20559-20565
-
-
Cuddeback, S.M.1
Yamaguchi, H.2
Komatsu, K.3
-
17
-
-
0038485614
-
Humanin peptide suppresses apoptosis by interfering with Bax activation
-
Guo B., Zhai D., Cabezas E., et al. Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature 423 (2003) 456-461
-
(2003)
Nature
, vol.423
, pp. 456-461
-
-
Guo, B.1
Zhai, D.2
Cabezas, E.3
-
18
-
-
0037385609
-
Ku70 suppresses the apoptotic translocation of Bax to mitochondria
-
Sawada M., Sun W., Hayes P., et al. Ku70 suppresses the apoptotic translocation of Bax to mitochondria. Nat Cell Biol 5 (2003) 320-329
-
(2003)
Nat Cell Biol
, vol.5
, pp. 320-329
-
-
Sawada, M.1
Sun, W.2
Hayes, P.3
-
19
-
-
1442335318
-
Control of mitochondrial permeability by Bcl-2 family members
-
Sharpe J.C., Arnoult D., and Youle R.J. Control of mitochondrial permeability by Bcl-2 family members. Biochim Biophys Acta 1644 (2004) 107-113
-
(2004)
Biochim Biophys Acta
, vol.1644
, pp. 107-113
-
-
Sharpe, J.C.1
Arnoult, D.2
Youle, R.J.3
-
21
-
-
0032723350
-
Bcl-2, Bcl-X, Bax, and Bak expression in short- and long-lived patients with diffuse large B-cell lymphomas
-
Bairey O., Zimra Y., Shaklai M., et al. Bcl-2, Bcl-X, Bax, and Bak expression in short- and long-lived patients with diffuse large B-cell lymphomas. Clin Cancer Res 5 (1999) 2860-2866
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2860-2866
-
-
Bairey, O.1
Zimra, Y.2
Shaklai, M.3
-
22
-
-
0037609669
-
Prognostic significance of bcl-2, bax, and p53 expression in diffuse large B-cell lymphoma
-
Sohn S.K., Jung J.T., Kim D.H., et al. Prognostic significance of bcl-2, bax, and p53 expression in diffuse large B-cell lymphoma. Am J Hematol 73 (2003) 101-107
-
(2003)
Am J Hematol
, vol.73
, pp. 101-107
-
-
Sohn, S.K.1
Jung, J.T.2
Kim, D.H.3
-
23
-
-
0036735241
-
Hepatocellular carcinoma and markers of apoptosis (bcl-2, bax, bcl-x). Prognostic significance
-
Garcia E.J., Lawson D., Cotsonis G., et al. Hepatocellular carcinoma and markers of apoptosis (bcl-2, bax, bcl-x). Prognostic significance. Appl Immunohistochem Mol Morphol 10 (2002) 210-217
-
(2002)
Appl Immunohistochem Mol Morphol
, vol.10
, pp. 210-217
-
-
Garcia, E.J.1
Lawson, D.2
Cotsonis, G.3
-
24
-
-
3042585770
-
Prognostic significance of Bcl-xL in human hepatocellular carcinoma
-
Watanabe J., Kushihata F., Honda K., et al. Prognostic significance of Bcl-xL in human hepatocellular carcinoma. Surgery 135 (2004) 604-612
-
(2004)
Surgery
, vol.135
, pp. 604-612
-
-
Watanabe, J.1
Kushihata, F.2
Honda, K.3
-
25
-
-
21744457447
-
Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival
-
Wuilleme-Toumi S., Robillard N., Gomez P., et al. Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival. Leukemia 19 (2005) 1248-1252
-
(2005)
Leukemia
, vol.19
, pp. 1248-1252
-
-
Wuilleme-Toumi, S.1
Robillard, N.2
Gomez, P.3
-
26
-
-
0032079746
-
Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia. Correlations with in vitro and in vivo chemoresponses
-
Kitada S., Andersen J., Akar S., et al. Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia. Correlations with in vitro and in vivo chemoresponses. Blood 91 (1998) 3379-3389
-
(1998)
Blood
, vol.91
, pp. 3379-3389
-
-
Kitada, S.1
Andersen, J.2
Akar, S.3
-
27
-
-
0347416908
-
Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia
-
Saxena A., Viswanathan S., Moshynska O., et al. Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia. Am J Hematol 75 (2004) 22-33
-
(2004)
Am J Hematol
, vol.75
, pp. 22-33
-
-
Saxena, A.1
Viswanathan, S.2
Moshynska, O.3
-
28
-
-
0031922256
-
Molecular mechanisms of antisense drugs. RNase H
-
Crooke S.T. Molecular mechanisms of antisense drugs. RNase H. Antisense Nucleic Acid Drug Dev 8 (1998) 133-134
-
(1998)
Antisense Nucleic Acid Drug Dev
, vol.8
, pp. 133-134
-
-
Crooke, S.T.1
-
29
-
-
0000015743
-
Antisense oligonucleotides. basic concepts and mechanisms
-
Dias N., and Stein C.A. Antisense oligonucleotides. basic concepts and mechanisms. Mol Cancer Ther 1 (2002) 347-355
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 347-355
-
-
Dias, N.1
Stein, C.A.2
-
30
-
-
5444256072
-
A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis
-
Simoes-Wust A.P., Hopkins-Donaldson S., Sigrist B., et al. A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis. Oligonucleotides 14 (2004) 199-209
-
(2004)
Oligonucleotides
, vol.14
, pp. 199-209
-
-
Simoes-Wust, A.P.1
Hopkins-Donaldson, S.2
Sigrist, B.3
-
31
-
-
33746710051
-
SPC2996-A Bcl-2 inhibitor for treatment of chronic lymphocytic leukemia
-
abstr A41
-
Hansen B., Westergaard M., Frieden M., et al. SPC2996-A Bcl-2 inhibitor for treatment of chronic lymphocytic leukemia. Clin Cancer Res 11 suppl (2005) 66 abstr A41
-
(2005)
Clin Cancer Res
, vol.11
, Issue.SUPPL
, pp. 66
-
-
Hansen, B.1
Westergaard, M.2
Frieden, M.3
-
32
-
-
0025011006
-
Antisense-mediated inhibition of BCL2 protooncogene expression and leukemic cell growth and survival. Comparisons of phosphodiester and phosphorothioate oligodeoxynucleotides
-
Reed J.C., Stein C., Subasinghe C., et al. Antisense-mediated inhibition of BCL2 protooncogene expression and leukemic cell growth and survival. Comparisons of phosphodiester and phosphorothioate oligodeoxynucleotides. Cancer Res 50 (1990) 6565-6570
-
(1990)
Cancer Res
, vol.50
, pp. 6565-6570
-
-
Reed, J.C.1
Stein, C.2
Subasinghe, C.3
-
33
-
-
0031907428
-
bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
Jansen B., Schlagbauer-Wadl H., Brown B.D., et al. bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 4 (1998) 232-234
-
(1998)
Nat Med
, vol.4
, pp. 232-234
-
-
Jansen, B.1
Schlagbauer-Wadl, H.2
Brown, B.D.3
-
34
-
-
0034083410
-
Eradication of human non-Hodgkin's lymphoma in SCID mice by BCL-2 antisense oligonucleotides combined with low-dose cyclophosphamide
-
Klasa R.J., Bally M.B., Ng R., et al. Eradication of human non-Hodgkin's lymphoma in SCID mice by BCL-2 antisense oligonucleotides combined with low-dose cyclophosphamide. Clin Cancer Res 6 (2000) 2492-2500
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2492-2500
-
-
Klasa, R.J.1
Bally, M.B.2
Ng, R.3
-
35
-
-
0033993970
-
Bcl-2 antisense oligonucleotides (G3139) inhibit Merkel cell carcinoma growth in SCID mice
-
Schlagbauer-Wadl H., Klosner G., Heere-Ress E., et al. Bcl-2 antisense oligonucleotides (G3139) inhibit Merkel cell carcinoma growth in SCID mice. J Invest Dermatol 114 (2000) 725-730
-
(2000)
J Invest Dermatol
, vol.114
, pp. 725-730
-
-
Schlagbauer-Wadl, H.1
Klosner, G.2
Heere-Ress, E.3
-
36
-
-
0034784534
-
Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model
-
Wacheck V., Heere-Ress E., Halaschek-Wiener J., et al. Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model. J Mol Med 79 (2001) 587-593
-
(2001)
J Mol Med
, vol.79
, pp. 587-593
-
-
Wacheck, V.1
Heere-Ress, E.2
Halaschek-Wiener, J.3
-
37
-
-
0032785072
-
Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides
-
Gleave M.E., Miayake H., and Goldie J. Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides. Urology 54 suppl 6A (1999) 36-46
-
(1999)
Urology
, vol.54
, Issue.SUPPL. 6A
, pp. 36-46
-
-
Gleave, M.E.1
Miayake, H.2
Goldie, J.3
-
38
-
-
0034684471
-
Chemosensitisation of malignant melanoma by BCL2 antisense therapy
-
Jansen B., Wacheck V., Heere-Ress E., et al. Chemosensitisation of malignant melanoma by BCL2 antisense therapy. Lancet 356 (2000) 1728-1733
-
(2000)
Lancet
, vol.356
, pp. 1728-1733
-
-
Jansen, B.1
Wacheck, V.2
Heere-Ress, E.3
-
39
-
-
0034794290
-
Preliminary phase I results of G3139 (bcl-2 antisense oligonucleotide) therapy in combination with docetaxel in hormone-refractory prostate cancer
-
Tolcher A.W. Preliminary phase I results of G3139 (bcl-2 antisense oligonucleotide) therapy in combination with docetaxel in hormone-refractory prostate cancer. Semin Oncol 28 suppl 15 (2001) 67-70
-
(2001)
Semin Oncol
, vol.28
, Issue.SUPPL. 15
, pp. 67-70
-
-
Tolcher, A.W.1
-
40
-
-
0036236808
-
A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer
-
Rudin C.M., Otterson G.A., Mauer A.M., et al. A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer. Ann Oncol 13 (2002) 539-545
-
(2002)
Ann Oncol
, vol.13
, pp. 539-545
-
-
Rudin, C.M.1
Otterson, G.A.2
Mauer, A.M.3
-
41
-
-
0037438586
-
Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia
-
Marcucci G., Byrd J.C., Dai G., et al. Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia. Blood 101 (2003) 425-432
-
(2003)
Blood
, vol.101
, pp. 425-432
-
-
Marcucci, G.1
Byrd, J.C.2
Dai, G.3
-
42
-
-
4444355922
-
A phase I trial of a Bcl-2 antisense (G3139) and weekly docetaxel in patients with advanced breast cancer and other solid tumors
-
Marshall J., Chen H., Yang D., et al. A phase I trial of a Bcl-2 antisense (G3139) and weekly docetaxel in patients with advanced breast cancer and other solid tumors. Ann Oncol 15 (2004) 1274-1283
-
(2004)
Ann Oncol
, vol.15
, pp. 1274-1283
-
-
Marshall, J.1
Chen, H.2
Yang, D.3
-
43
-
-
1842562213
-
Phase I study of G3139, a bcl-2 antisense oligonucleotide, combined with carboplatin and etoposide in patients with small-cell lung cancer
-
Rudin C.M., Kozloff M., Hoffman P.C., et al. Phase I study of G3139, a bcl-2 antisense oligonucleotide, combined with carboplatin and etoposide in patients with small-cell lung cancer. J Clin Oncol 22 (2004) 1110-1117
-
(2004)
J Clin Oncol
, vol.22
, pp. 1110-1117
-
-
Rudin, C.M.1
Kozloff, M.2
Hoffman, P.C.3
-
44
-
-
4243079972
-
A phase I pharmacokinetic and biological correlative study of oblimersen sodium (Genasense, G3139), an antisense oligonucleotide to the Bcl-2 mRNA, and of docetaxel in patients with hormone-refractory prostate cancer
-
Tolcher A.W., Kuhn J., Schwartz G., et al. A phase I pharmacokinetic and biological correlative study of oblimersen sodium (Genasense, G3139), an antisense oligonucleotide to the Bcl-2 mRNA, and of docetaxel in patients with hormone-refractory prostate cancer. Clin Cancer Res 10 (2004) 5048-5057
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5048-5057
-
-
Tolcher, A.W.1
Kuhn, J.2
Schwartz, G.3
-
45
-
-
21044431880
-
A phase II, pharmacokinetic, and biological correlative study of oblimersen sodium and docetaxel in patients with hormone-refractory prostate cancer
-
Tolcher A.W., Chi K., Kuhn J., et al. A phase II, pharmacokinetic, and biological correlative study of oblimersen sodium and docetaxel in patients with hormone-refractory prostate cancer. Clin Cancer Res 11 (2005) 3854-3861
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3854-3861
-
-
Tolcher, A.W.1
Chi, K.2
Kuhn, J.3
-
46
-
-
20644469046
-
Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia. Pharmacokinetics, pharmacodynamics, and clinical activity
-
Marcucci G., Stock W., Dai G., et al. Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia. Pharmacokinetics, pharmacodynamics, and clinical activity. J Clin Oncol 23 (2005) 3404-3411
-
(2005)
J Clin Oncol
, vol.23
, pp. 3404-3411
-
-
Marcucci, G.1
Stock, W.2
Dai, G.3
-
47
-
-
18144366606
-
Early results of a phase I trial of oblimersen sodium for relapsed or refractory Waldenstrom's macroglobulinemia
-
Gertz M.A., Geyer S.M., Badros A., et al. Early results of a phase I trial of oblimersen sodium for relapsed or refractory Waldenstrom's macroglobulinemia. Clin Lymphoma 5 (2005) 282-284
-
(2005)
Clin Lymphoma
, vol.5
, pp. 282-284
-
-
Gertz, M.A.1
Geyer, S.M.2
Badros, A.3
-
48
-
-
0030888664
-
BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
-
Webb A., Cunningham D., Cotter F., et al. BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet 349 (1997) 1137-1141
-
(1997)
Lancet
, vol.349
, pp. 1137-1141
-
-
Webb, A.1
Cunningham, D.2
Cotter, F.3
-
49
-
-
0034015672
-
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
-
Waters J.S., Webb A., Cunningham D., et al. Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. J Clin Oncol 18 (2000) 1812-1823
-
(2000)
J Clin Oncol
, vol.18
, pp. 1812-1823
-
-
Waters, J.S.1
Webb, A.2
Cunningham, D.3
-
50
-
-
0036303535
-
Phase I trial of BCL-2 antisense oligonucleotide (G3139) administered by continuous intravenous infusion in patients with advanced cancer
-
Morris M.J., Tong W.P., Cordon-Cardo C., et al. Phase I trial of BCL-2 antisense oligonucleotide (G3139) administered by continuous intravenous infusion in patients with advanced cancer. Clin Cancer Res 8 (2002) 679-683
-
(2002)
Clin Cancer Res
, vol.8
, pp. 679-683
-
-
Morris, M.J.1
Tong, W.P.2
Cordon-Cardo, C.3
-
51
-
-
32944475363
-
Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia
-
O'Brien S.M., Cunningham C.C., Golenkov A.K., et al. Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia. J Clin Oncol 23 (2005) 7697-7702
-
(2005)
J Clin Oncol
, vol.23
, pp. 7697-7702
-
-
O'Brien, S.M.1
Cunningham, C.C.2
Golenkov, A.K.3
-
52
-
-
20444435635
-
Randomized multicenter phase 3 trial of high-dose dexamethasone (dex) with or without oblimersen sodium (G3139; Bcl-2 antisense; Genasense) for patients with advanced multiple myeloma (MM)
-
(abstr)
-
Chanan-Khan A.A., Niesvizky R., Hohl R.J., et al. Randomized multicenter phase 3 trial of high-dose dexamethasone (dex) with or without oblimersen sodium (G3139; Bcl-2 antisense; Genasense) for patients with advanced multiple myeloma (MM). ASH Annual Meeting Abstracts 104 (2004) 1477 (abstr)
-
(2004)
ASH Annual Meeting Abstracts
, vol.104
, pp. 1477
-
-
Chanan-Khan, A.A.1
Niesvizky, R.2
Hohl, R.J.3
-
53
-
-
23844475163
-
Long-term survival results of a randomized multinational phase 3 trial of dacarbazine (DTIC) with or without Bcl-2 antisense (oblimersen sodium) in patients (pts) with advanced malignant melanoma (MM)
-
(abstr)
-
Kirkwood J.M., Bedikian A.Y., Millward M.J., et al. Long-term survival results of a randomized multinational phase 3 trial of dacarbazine (DTIC) with or without Bcl-2 antisense (oblimersen sodium) in patients (pts) with advanced malignant melanoma (MM). J Clin Oncol (Meeting Abstracts) 23 suppl 16 (2005) 7506 (abstr)
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.SUPPL. 16
, pp. 7506
-
-
Kirkwood, J.M.1
Bedikian, A.Y.2
Millward, M.J.3
-
54
-
-
20344387097
-
Phase 3 randomized trial of fludarabine/cyclophosphamide chemotherapy with or without oblimersen sodium (Bcl-2 antisense; Genasense; G3139) for patients with relapsed or refractory chronic lymphocytic leukemia (CLL)
-
(abstr)
-
Rai K.R., Moore J.O., Boyd T.E., et al. Phase 3 randomized trial of fludarabine/cyclophosphamide chemotherapy with or without oblimersen sodium (Bcl-2 antisense; Genasense; G3139) for patients with relapsed or refractory chronic lymphocytic leukemia (CLL). ASH Annual Meeting Abstracts 104 (2004) 338 (abstr)
-
(2004)
ASH Annual Meeting Abstracts
, vol.104
, pp. 338
-
-
Rai, K.R.1
Moore, J.O.2
Boyd, T.E.3
-
55
-
-
0036850631
-
Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides
-
Dias N., and Stein C.A. Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides. Eur J Pharm Biopharm 54 (2002) 263-269
-
(2002)
Eur J Pharm Biopharm
, vol.54
, pp. 263-269
-
-
Dias, N.1
Stein, C.A.2
-
56
-
-
23044452536
-
Phase II study of G3139, a Bcl-2 antisense oligonucleotide, in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients
-
Badros A.Z., Goloubeva O., Rapoport A.P., et al. Phase II study of G3139, a Bcl-2 antisense oligonucleotide, in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients. J Clin Oncol 23 (2005) 4089-4099
-
(2005)
J Clin Oncol
, vol.23
, pp. 4089-4099
-
-
Badros, A.Z.1
Goloubeva, O.2
Rapoport, A.P.3
-
57
-
-
0347444723
-
MicroRNAs. Fenomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs. Fenomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
58
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y., Ahn C., Han J., et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 425 (2003) 415-419
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
-
59
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E., Caudy A.A., Hammond S.M., et al. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409 (2001) 363-366
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
-
60
-
-
14844364472
-
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
-
Cheng A.M., Byrom M.W., Shelton J., et al. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 33 (2005) 1290-1297
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 1290-1297
-
-
Cheng, A.M.1
Byrom, M.W.2
Shelton, J.3
-
61
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin G.A., Sevignani C., Dumitru C.D., et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101 (2004) 2999-3004
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
62
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin G.A., Dumitru C.D., Shimizu M., et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 99 (2002) 15524-15529
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
63
-
-
14844354250
-
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
-
Eis P.S., Tam W., Sun L., et al. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci U S A 102 (2005) 3627-3632
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3627-3632
-
-
Eis, P.S.1
Tam, W.2
Sun, L.3
-
64
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A., Calin G.A., Fabbri M., et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A 102 (2005) 13944-13949
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
-
65
-
-
0345829926
-
Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents
-
Mercatante D.R., Mohler J.L., and Kole R. Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents. J Biol Chem 277 (2002) 49374-49382
-
(2002)
J Biol Chem
, vol.277
, pp. 49374-49382
-
-
Mercatante, D.R.1
Mohler, J.L.2
Kole, R.3
-
66
-
-
4444342586
-
Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma
-
Ozvaran M.K., Cao X.X., Miller S.D., et al. Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma. Mol Cancer Ther 3 (2004) 545-550
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 545-550
-
-
Ozvaran, M.K.1
Cao, X.X.2
Miller, S.D.3
-
67
-
-
0035925537
-
Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins
-
Gautschi O., Tschopp S., Olie R.A., et al. Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins. J Natl Cancer Inst 93 (2001) 463-471
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 463-471
-
-
Gautschi, O.1
Tschopp, S.2
Olie, R.A.3
-
69
-
-
13944274500
-
Mcl-1 regulation and its role in multiple myeloma
-
Le Gouill S., Podar K., and Harousseau J.L. Mcl-1 regulation and its role in multiple myeloma. Cell Cycle 3 (2004) 1259-1262
-
(2004)
Cell Cycle
, vol.3
, pp. 1259-1262
-
-
Le Gouill, S.1
Podar, K.2
Harousseau, J.L.3
-
70
-
-
4544348358
-
Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia
-
Johnston J.B., Paul J.T., Neufeld N.J., et al. Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia. Leuk Lymphoma 45 (2004) 2017-2027
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 2017-2027
-
-
Johnston, J.B.1
Paul, J.T.2
Neufeld, N.J.3
-
71
-
-
0348223928
-
Prognostic value of apoptosis-regulating protein expression in anal squamous cell carcinoma
-
Allal A.S., Waelchli L., and Brundler M.A. Prognostic value of apoptosis-regulating protein expression in anal squamous cell carcinoma. Clin Cancer Res 9 (2003) 6489-6496
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6489-6496
-
-
Allal, A.S.1
Waelchli, L.2
Brundler, M.A.3
-
72
-
-
20144388297
-
Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML). Evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides
-
Aichberger K.J., Mayerhofer M., Krauth M.T., et al. Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML). Evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides. Blood 105 (2005) 3303-3311
-
(2005)
Blood
, vol.105
, pp. 3303-3311
-
-
Aichberger, K.J.1
Mayerhofer, M.2
Krauth, M.T.3
-
73
-
-
33746724220
-
Targeting Mcl1 exhibits a strong single agent activity in hepatocellular carcinoma
-
(abstr 626)
-
Sieghart W., Losert D., Strommer S., et al. Targeting Mcl1 exhibits a strong single agent activity in hepatocellular carcinoma. Eur J Cancer s2 (2004) 189 (abstr 626)
-
(2004)
Eur J Cancer
, vol.s2
, pp. 189
-
-
Sieghart, W.1
Losert, D.2
Strommer, S.3
-
74
-
-
3042570258
-
Mcl-1 is a novel therapeutic target for human sarcoma. synergistic inhibition of human sarcoma xenotransplants by a combination of mcl-1 antisense oligonucleotides with low-dose cyclophosphamide
-
Thallinger C., Wolschek M.F., Maierhofer H., et al. Mcl-1 is a novel therapeutic target for human sarcoma. synergistic inhibition of human sarcoma xenotransplants by a combination of mcl-1 antisense oligonucleotides with low-dose cyclophosphamide. Clin Cancer Res 10 (2004) 4185-4191
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4185-4191
-
-
Thallinger, C.1
Wolschek, M.F.2
Maierhofer, H.3
-
75
-
-
27144502652
-
The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006
-
Yu C., Bruzek L.M., Meng X.W., et al. The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006. Oncogene 24 (2005) 6861-6869
-
(2005)
Oncogene
, vol.24
, pp. 6861-6869
-
-
Yu, C.1
Bruzek, L.M.2
Meng, X.W.3
-
76
-
-
4444291734
-
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
-
Walensky L.D., Kung A.L., Escher I., et al. Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix. Science 305 (2004) 1466-1470
-
(2004)
Science
, vol.305
, pp. 1466-1470
-
-
Walensky, L.D.1
Kung, A.L.2
Escher, I.3
-
77
-
-
0025313476
-
Biochemical correlates of the antitumor and antimitochondrial properties of gossypol enantiomers
-
Benz C.C., Keniry M.A., Ford J.M., et al. Biochemical correlates of the antitumor and antimitochondrial properties of gossypol enantiomers. Mol Pharmacol 37 (1990) 840-847
-
(1990)
Mol Pharmacol
, vol.37
, pp. 840-847
-
-
Benz, C.C.1
Keniry, M.A.2
Ford, J.M.3
-
78
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
Wang J.-L., Liu D., Zhang Z.-J., et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc Natl Acad Sci U S A 97 (2000) 7124-7129
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7124-7129
-
-
Wang, J.-L.1
Liu, D.2
Zhang, Z.-J.3
-
79
-
-
0035150803
-
Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL
-
Degterev A., Lugovskoy A., Cardone M., et al. Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Nat Cell Biol 3 (2001) 173-182
-
(2001)
Nat Cell Biol
, vol.3
, pp. 173-182
-
-
Degterev, A.1
Lugovskoy, A.2
Cardone, M.3
-
80
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
Tzung S.P., Kim K.M., Basanez G., et al. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nat Cell Biol 3 (2001) 183-191
-
(2001)
Nat Cell Biol
, vol.3
, pp. 183-191
-
-
Tzung, S.P.1
Kim, K.M.2
Basanez, G.3
-
81
-
-
0347626109
-
Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins
-
Leone M., Zhai D., Sareth S., et al. Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins. Cancer Res 63 (2003) 8118-8121
-
(2003)
Cancer Res
, vol.63
, pp. 8118-8121
-
-
Leone, M.1
Zhai, D.2
Sareth, S.3
-
82
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T., Elmore S.W., Shoemaker A.R., et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435 (2005) 677-681
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
-
83
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
Wang J.L., Liu D., Zhang Z.J., et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc Natl Acad Sci U S A 97 (2000) 7124-7129
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7124-7129
-
-
Wang, J.L.1
Liu, D.2
Zhang, Z.J.3
-
84
-
-
0242475256
-
HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death
-
Lickliter J.D., Wood N.J., Johnson L., et al. HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death. Leukemia 17 (2003) 2074-2080
-
(2003)
Leukemia
, vol.17
, pp. 2074-2080
-
-
Lickliter, J.D.1
Wood, N.J.2
Johnson, L.3
-
85
-
-
30144441345
-
HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells
-
Skommer J., Wlodkowic D., and Matto M. HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells. Leuk Res 30 (2006) 322-331
-
(2006)
Leuk Res
, vol.30
, pp. 322-331
-
-
Skommer, J.1
Wlodkowic, D.2
Matto, M.3
-
86
-
-
0034922672
-
Oral gossypol in the treatment of patients with refractory metastatic breast cancer. A phase I/II clinical trial
-
Van Poznak C., Seidman A.D., and Reidenberg M.M. Oral gossypol in the treatment of patients with refractory metastatic breast cancer. A phase I/II clinical trial. Breast Cancer Res Treat 66 (2001) 239-248
-
(2001)
Breast Cancer Res Treat
, vol.66
, pp. 239-248
-
-
Van Poznak, C.1
Seidman, A.D.2
Reidenberg, M.M.3
-
87
-
-
0141569444
-
Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins
-
Kitada S., Leone M., Sareth S., et al. Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins. J Med Chem 46 (2003) 4259-4264
-
(2003)
J Med Chem
, vol.46
, pp. 4259-4264
-
-
Kitada, S.1
Leone, M.2
Sareth, S.3
-
88
-
-
22144460556
-
Apoptosis-based therapies for hematologic malignancies
-
Reed J.C., and Pellecchia M. Apoptosis-based therapies for hematologic malignancies. Blood 106 (2005) 408-418
-
(2005)
Blood
, vol.106
, pp. 408-418
-
-
Reed, J.C.1
Pellecchia, M.2
-
89
-
-
0027460576
-
Oral gossypol in the treatment of metastatic adrenal cancer
-
Flack M., Pyle R., Mullen N., et al. Oral gossypol in the treatment of metastatic adrenal cancer. J Clin Endocrinol Metab 76 (1993) 1019-1024
-
(1993)
J Clin Endocrinol Metab
, vol.76
, pp. 1019-1024
-
-
Flack, M.1
Pyle, R.2
Mullen, N.3
-
90
-
-
0032780442
-
Gossypol treatment of recurrent adult malignant gliomas
-
Bushunow P., Reidenberg M.M., Wasenko J., et al. Gossypol treatment of recurrent adult malignant gliomas. J Neurooncol 43 (1999) 79-86
-
(1999)
J Neurooncol
, vol.43
, pp. 79-86
-
-
Bushunow, P.1
Reidenberg, M.M.2
Wasenko, J.3
-
91
-
-
1942529509
-
Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L)
-
Becattini B., Kitada S., Leone M., et al. Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L). Chem Biol 11 (2004) 389-395
-
(2004)
Chem Biol
, vol.11
, pp. 389-395
-
-
Becattini, B.1
Kitada, S.2
Leone, M.3
-
92
-
-
0036244595
-
The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer
-
Liu S., Kulp S.K., Sugimoto Y., et al. The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer. Anticancer Res 22 (2002) 33-38
-
(2002)
Anticancer Res
, vol.22
, pp. 33-38
-
-
Liu, S.1
Kulp, S.K.2
Sugimoto, Y.3
-
93
-
-
9344226187
-
In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells
-
Oliver C.L., Bauer J.A., Wolter K.G., et al. In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res 10 (2004) 7757-7763
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7757-7763
-
-
Oliver, C.L.1
Bauer, J.A.2
Wolter, K.G.3
-
94
-
-
23144467530
-
Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells. Role of wild-type p53 and Bcl-xL
-
Bauer J.A., Trask D.K., Kumar B., et al. Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells. Role of wild-type p53 and Bcl-xL. Mol Cancer Ther 4 (2005) 1096-1104
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1096-1104
-
-
Bauer, J.A.1
Trask, D.K.2
Kumar, B.3
-
95
-
-
20044368078
-
(-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer
-
Xu L., Yang D., Wang S., et al. (-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer. Mol Cancer Ther 4 (2005) 197-205
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 197-205
-
-
Xu, L.1
Yang, D.2
Wang, S.3
-
96
-
-
33645112969
-
Preclinical evaluation of apoptosis induction by the novel small molecule BCL-2 inhibitor, GX015-070, in ex vivo chronic lymphoid leukemia (CLL) cells
-
(abstr)
-
Olney H.J., Weng X., Watson M., et al. Preclinical evaluation of apoptosis induction by the novel small molecule BCL-2 inhibitor, GX015-070, in ex vivo chronic lymphoid leukemia (CLL) cells. J Clin Oncol (Meeting Abstracts) 23 suppl 16 (2005) 3149 (abstr)
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.SUPPL. 16
, pp. 3149
-
-
Olney, H.J.1
Weng, X.2
Watson, M.3
-
97
-
-
33746750974
-
Initial results from ongoing phase I trials of a novel pan bcl-2 family small molecule inhibitor
-
(abstr)
-
McGreivy J.S., Marshall J., Cheson B.D., et al. Initial results from ongoing phase I trials of a novel pan bcl-2 family small molecule inhibitor. J Clin Oncol (Meeting Abstracts) 23 suppl 16 (2005) 3180 (abstr)
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.SUPPL. 16
, pp. 3180
-
-
McGreivy, J.S.1
Marshall, J.2
Cheson, B.D.3
-
98
-
-
33746761713
-
GX15-070MS, a synthetic small molecule induces apoptosis in vitro and in vivo in chronic lymphocytic leukemia
-
(abstr)
-
Castro J.E., Prada C.E., Kitada S., et al. GX15-070MS, a synthetic small molecule induces apoptosis in vitro and in vivo in chronic lymphocytic leukemia. J Clin Oncol (Meeting Abstracts) 23 suppl 16 (2005) 3167 (abstr)
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.SUPPL. 16
, pp. 3167
-
-
Castro, J.E.1
Prada, C.E.2
Kitada, S.3
-
99
-
-
1342306819
-
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
-
Lin B., Kolluri S.K., Lin F., et al. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 116 (2004) 527-540
-
(2004)
Cell
, vol.116
, pp. 527-540
-
-
Lin, B.1
Kolluri, S.K.2
Lin, F.3
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