-
1
-
-
0033118755
-
Insights from Bcl-2 and Myc: Malignancy involves abrogation of apoptosis as well as sustained proliferation
-
Cory S, Vaux DL, Strasser A, Harris AW, Adams JM. Insights from Bcl-2 and Myc: malignancy involves abrogation of apoptosis as well as sustained proliferation. Cancer Res 1999; 59 (Suppl): 1685s-1692s.
-
(1999)
Cancer Res.
, vol.59
, Issue.SUPPL.
-
-
Cory, S.1
Vaux, D.L.2
Strasser, A.3
Harris, A.W.4
Adams, J.M.5
-
2
-
-
0034953712
-
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis
-
Eischen CM, Woo D, Roussel MF, Cleveland TL. Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis. Mol Cell Biol 2001; 21: 5063-5070.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 5063-5070
-
-
Eischen, C.M.1
Woo, D.2
Roussel, M.F.3
Cleveland, T.L.4
-
3
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed JC. Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999; 11: 68-75.
-
(1999)
Curr. Opin. Oncol.
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
4
-
-
0028972728
-
Bcl-XL protects cancer cells from p53-mediated apoptosis
-
Schott AF, Apel IJ, Nunez G, Clarke MF. Bcl-XL protects cancer cells from p53-mediated apoptosis. Oncogene 1995; 11: 1389-1394.
-
(1995)
Oncogene
, vol.11
, pp. 1389-1394
-
-
Schott, A.F.1
Apel, I.J.2
Nunez, G.3
Clarke, M.F.4
-
5
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-921.
-
(1997)
Nat. Med.
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
7
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams JM, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 1998; 281: 1322-1326.
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
8
-
-
0036097786
-
Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath H, Strasser A. Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002; 9: 505-512.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
9
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2002; 2: 183-192.
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
10
-
-
0036773678
-
The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules
-
Huang Z. The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules. Chem Biol 2002; 9: 1059-1072.
-
(2002)
Chem. Biol.
, vol.9
, pp. 1059-1072
-
-
Huang, Z.1
-
11
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
Vaux DL, Cory S, Adams JM. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335: 440-442.
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
12
-
-
0031030034
-
Measurement of spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia
-
Banker DE, Groudine M, Norwood T, Appelbaum FR. Measurement of spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia. Blood 1997; 89: 243-255.
-
(1997)
Blood
, vol.89
, pp. 243-255
-
-
Banker, D.E.1
Groudine, M.2
Norwood, T.3
Appelbaum, F.R.4
-
13
-
-
0032907685
-
Expression of apoptosis-controlling proteins in acute leukemia cells
-
Campos L, Sabido O, Viallet A, Vasselon C, Guyotat D. Expression of apoptosis-controlling proteins in acute leukemia cells. Leuk Lymphoma 1999; 33: 499-509.
-
(1999)
Leuk. Lymphoma
, vol.33
, pp. 499-509
-
-
Campos, L.1
Sabido, O.2
Viallet, A.3
Vasselon, C.4
Guyotat, D.5
-
14
-
-
0032808894
-
Bcl-6 and Bcl-2 protein expression in diffuse large B-cell lymphoma and follicular lymphoma: Correlation with 3q27 and 18q21 chromosomal abnormalities
-
Skinnider BF, Horsman DE, Dupuis B, Gascoyne RD. Bcl-6 and Bcl-2 protein expression in diffuse large B-cell lymphoma and follicular lymphoma: correlation with 3q27 and 18q21 chromosomal abnormalities. Hum Pathol 1999; 30: 803-808.
-
(1999)
Hum. Pathol.
, vol.30
, pp. 803-808
-
-
Skinnider, B.F.1
Horsman, D.E.2
Dupuis, B.3
Gascoyne, R.D.4
-
15
-
-
0028066802
-
Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model
-
Cotter FE, Johnson P, Hall P, Pocock C, al Mahdi N, Cowell JK et al. Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model. Oncogene 1994; 9: 3049-3055.
-
(1994)
Oncogene
, vol.9
, pp. 3049-3055
-
-
Cotter, F.E.1
Johnson, P.2
Hall, P.3
Pocock, C.4
al Mahdi, N.5
Cowell, J.K.6
-
16
-
-
0031907428
-
bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
Jansen B, Schlagbauer-Wadl H, Brown BD, Bryan RN, van Elsas A, Muller M et al. bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 1998; 4: 232-234.
-
(1998)
Nat. Med.
, vol.4
, pp. 232-234
-
-
Jansen, B.1
Schlagbauer-Wadl, H.2
Brown, B.D.3
Bryan, R.N.4
van Elsas, A.5
Muller, M.6
-
17
-
-
0034203953
-
Clinical studies of antisense therapy in cancer
-
Yuen AR, Sikic BI. Clinical studies of antisense therapy in cancer. Front Biosci 2000; 5: D588-D593.
-
(2000)
Front Biosci.
, vol.5
-
-
Yuen, A.R.1
Sikic, B.I.2
-
18
-
-
0034015672
-
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
-
Waters JS, Webb A, Cunningham D, Clarke PA, Raynaud F, di Stefano F et al. Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. J Clin Oncol 2000; 18: 1812-1823.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 1812-1823
-
-
Waters, J.S.1
Webb, A.2
Cunningham, D.3
Clarke, P.A.4
Raynaud, F.5
di Stefano, F.6
-
19
-
-
0036303535
-
Phase I trial of BCL-2 antisense oligonucleotide (G3139) administered by continuous intravenous infusion in patients with advanced cancer
-
Morris MJ, Tong WP, Cordon-Cardo C, Drobnjak M, Kelly WK, Slovin SF et al. Phase I trial of BCL-2 antisense oligonucleotide (G3139) administered by continuous intravenous infusion in patients with advanced cancer. Clin Cancer Res 2002; 8: 679-683.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 679-683
-
-
Morris, M.J.1
Tong, W.P.2
Cordon-Cardo, C.3
Drobnjak, M.4
Kelly, W.K.5
Slovin, S.F.6
-
20
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
Wang JL, Liu D, Zhang ZJ, Shan S, Han X, Srinivasula SM et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc Natl Acad Sci USA 2000; 97: 7124-7129.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7124-7129
-
-
Wang, J.L.1
Liu, D.2
Zhang, Z.J.3
Shan, S.4
Han, X.5
Srinivasula, S.M.6
-
21
-
-
0037081329
-
Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells
-
Yamaguchi H, Paranawithana SR. Lee MW, Huang Z, Bhalla KN, Wang HG. Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells. Cancer Res 2002; 62: 466-471.
-
(2002)
Cancer Res.
, vol.62
, pp. 466-471
-
-
Yamaguchi, H.1
Paranawithana, S.R.2
Lee, M.W.3
Huang, Z.4
Bhalla, K.N.5
Wang, H.G.6
-
22
-
-
0036566242
-
Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
-
Milella M, Estrov Z, Kornblau SM, Carter BZ, Konopleva M, Tari A et al. Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia. Blood 2002; 99: 3461-3464.
-
(2002)
Blood
, vol.99
, pp. 3461-3464
-
-
Milella, M.1
Estrov, Z.2
Kornblau, S.M.3
Carter, B.Z.4
Konopleva, M.5
Tari, A.6
-
23
-
-
0033759002
-
Controlling the mitochondrial gatekeeper for effective chemotherapy
-
Fennell DA, Cotter FE. Controlling the mitochondrial gatekeeper for effective chemotherapy. Br J Haematol 2000; 111: 52-60.
-
(2000)
Br. J. Haematol.
, vol.111
, pp. 52-60
-
-
Fennell, D.A.1
Cotter, F.E.2
-
24
-
-
0026492817
-
Features of apoptotic cells measured by flow cytometry
-
Darzynkiewicz Z, Bruno S, Del Bino G, Gorczyca W, Hotz MA, Lassota P et al. Features of apoptotic cells measured by flow cytometry. Cytometry 1992; 13: 795-808.
-
(1992)
Cytometry
, vol.13
, pp. 795-808
-
-
Darzynkiewicz, Z.1
Bruno, S.2
Del Bino, G.3
Gorczyca, W.4
Hotz, M.A.5
Lassota, P.6
-
25
-
-
0036721023
-
Glucocorticoids and rituximab in vitro: Synergistic direct antiproliferative and apoptotic effects
-
Rose AL, Smith BE, Maloney DG. Glucocorticoids and rituximab in vitro: synergistic direct antiproliferative and apoptotic effects. Blood 2002; 100: 1765-1773.
-
(2002)
Blood
, vol.100
, pp. 1765-1773
-
-
Rose, A.L.1
Smith, B.E.2
Maloney, D.G.3
-
26
-
-
0033043803
-
Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins
-
Meilhac O, Escargueil-Blanc I, Thiers JC, Salvayre R, Negre-Salvayre A. Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins. FASEB J 1999; 13: 485-494.
-
(1999)
FASEB J.
, vol.13
, pp. 485-494
-
-
Meilhac, O.1
Escargueil-Blanc, I.2
Thiers, J.C.3
Salvayre, R.4
Negre-Salvayre, A.5
-
27
-
-
0032504709
-
Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
-
1366
-
Halestrap AP, Kerr PM, Javadov S, Woodfield KY. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1998; 1366: 79-94.
-
(1998)
Biochim. Biophys. Acta
, pp. 79-94
-
-
Halestrap, A.P.1
Kerr, P.M.2
Javadov, S.3
Woodfield, K.Y.4
-
28
-
-
3042766027
-
The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195
-
Chen J, Freeman A, Liu J, Dai Q, Lee RM. The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195. Mol Cancer Ther 2002; 1: 961-967.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 961-967
-
-
Chen, J.1
Freeman, A.2
Liu, J.3
Dai, Q.4
Lee, R.M.5
-
29
-
-
0029961350
-
In vitro expansion of hematopoietic progenitor cells induces functional expression of Fas antigen (CD95)
-
Takenaka K, Nagafuji K, Harada M, Mizuno S, Miyamoto T, Makino S et al. In vitro expansion of hematopoietic progenitor cells induces functional expression of Fas antigen (CD95). Blood 1996; 88: 2871-2877.
-
(1996)
Blood
, vol.88
, pp. 2871-2877
-
-
Takenaka, K.1
Nagafuji, K.2
Harada, M.3
Mizuno, S.4
Miyamoto, T.5
Makino, S.6
-
30
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
Tzung SP, Kim KM, Basanez G, Giedt CD, Simon J, Zimmerberg J et al. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nat Cell Biol 2001; 3: 183-191.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 183-191
-
-
Tzung, S.P.1
Kim, K.M.2
Basanez, G.3
Giedt, C.D.4
Simon, J.5
Zimmerberg, J.6
-
31
-
-
0035818885
-
Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening
-
Enyedy IJ, Ling Y, Nacro K, Tomita Y, Wu X, Cao Y et al. Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening. J Med Chem 2001; 44: 4313-4324.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 4313-4324
-
-
Enyedy, I.J.1
Ling, Y.2
Nacro, K.3
Tomita, Y.4
Wu, X.5
Cao, Y.6
|