Sequence analysis of the entire mitochondrial genome in parkinson’s disease

Biochemical and Biophysical Research Communications

Volumn 290, Issue 5, 2002, Pages 1593-1601

  Vives Bauza, Cristofol ^a   Andreu, Antoni L ^a   Manfredi, Giovanni ^b   Beal, M Flint ^b   Lin, Michael T ^b   Janetzky, Bernd ^c   Gruenewald, Thomas H ^c  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Mitochondrial DNA; Parkinson s disease; Sequencing

Indexed keywords

MITOCHONDRIAL DNA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; HUMAN; HUMAN TISSUE; MISSENSE MUTATION; MITOCHONDRIAL GENETICS; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SUBSTANTIA NIGRA;

EID: 0036297660     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6388     Document Type: Article

References (38)

1. Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson’s disease and dementia with Lewy bodies
2. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
3. Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease
4. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
5. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1, 2, 5, 6-tetrahydropyridine
6. Chronic systemic pesticide exposure reproduces features of Parkinson’s disease
7. Mitochondrial complex I deficiency in Parkinson’s disease
8. Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation
9. A novel mitochondrial 12S rRNA point mutation in parkinsonism, deafness, and neuropathy
10. Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson’s disease family
11. Origin and functional consequences of the complex I defect in Parkinson’s disease
12. Mitochondrial DNA transmission of the mitochondrial defect in Parkinson’s disease
13. Cytoplasmic transfer of platelet mtDNA from elderly patients with Parkinson’s disease to mtDNA-less HeLa cells restores complete mitochondrial respiratory function
14. Mitochondrial DNA sequence analysis of four Alzheimer’s and Parkinson’s disease patients
15. Mitochondrial DNA polymorphism in substantia nigra
16. Mitochondrial tRNA(Gln) and tRNA(Thr) gene variants in Parkinson’s disease
17. Two novel point mutations of mitochondrial tRNA genes in histologically confirmed Parkinson disease
18. Mitochondrial DNA polymorphisms in pathologically proven Parkinson’s disease
19. Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson’s disease
20. Parkinson disease: Analysis of mitochondrial DNA in monozygotic twins
21. Automating the identification of DNA variations using quality-based fluorescence re-sequencing: Analysis of the human mitochondrial genome
22. The emerging tree of West EurAsian mtDNAs: A synthesis of control-region sequences and RFLPs
23. New mitochondrial DNA homoplasmic mutations associated with Japanese patients with type 2 diabetes
24. MITOMAP: A human mitochondrial genome database-1998 update
25. Mutations in mitochondrial tRNA genes: A frequent cause of neuromuscular diseases
26. Mutations in mitochondrial tRNA genes: Non-linkage with syndromes of Wolfram and chronic progressive external ophthalmoplegia
27. Phylogenetic analysis of Leber’s hereditary optic neuropathy mitochondrial DNA’s indicates multiple independent occurrences of the common mutations
28. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
29. The A1555G mutation in the 12S rRNA gene of human mtDNA: Recurrent origins and founder events in families affected by sensorineural deafness
30. Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
31. A frameshift mitochondrial complex I gene mutation in a patient with dystonia and cataracts: Is the mutation pathogenic?
32. About the "Pathological" role of the mtDNA T3308C mutationellipsis
33. Autosomal dominant progressive external ophthalmoplegia: Distribution of multiple mitochondrial DNA deletions
34. Accumulation of deletions and point mutations in mitochondrial genome in degenerative diseases
35. High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer’s disease brain
36. A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice
37. Nuclear background determines biochemical phenotype in the deafness-associated mitochondrial 12S rRNA mutation