Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease

Neuroscience Letters

Volumn 344, Issue 2, 2003, Pages 99-102

  Styczynska, Maria ^a   Religa, Dorota ^a,b   Pfeffer, Anna ^a   Luczywek, Elzbieta ^a   Wasiak, Boguslaw ^a   Styczynski, Grzegorz ^c   Peplonska, Beata ^a   Gabryelewicz, Tomasz ^a   Golebiowski, Marek ^c   Kobrys, Malgorzata ^a   Barcikowska, Maria ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Alzheimer's disease; Apolipoprotein E; Cathepsin D; Myeloperoxidase; Nitric oxide synthase; Polymorphism; 2 Macroglobulin

Indexed keywords

ALPHA 2 MACROGLOBULIN; APOLIPOPROTEIN E; CATHEPSIN D; MYELOPEROXIDASE; NITRIC OXIDE SYNTHASE;

AGED; ALLELE; ALZHEIMER DISEASE; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; POLAND; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; RISK FACTOR;

EID: 0038018658     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00438-5     Document Type: Review

References (21)

1. Bertram L., Blacker D., Mullin K., Keeney D., Jones J., Basu S., Yhu S., McInnis M., Go R., Vekrellis K., Selkoe D., Saunders A., Tanzi R. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science. 290:2000;2302-2303.
2. Bhojak T., Dekosky S., Ganguli M., Kamboh M. Genetic polymorphisms in the cathepsin D and interleukin-6 genes and the risk of Alzheimer's disease. Neurosci. Lett. 288:2000;21-24.
3. Blacker D., Wilcox M.A., Laird N.M., Rodes L., Horvath S., Go R., Perry R., Watson B., Bassett S., McInnis M., Albert M., Hyman B., Tanzi R. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat. Genet. 19:1998;357-360.
4. Boussaha M., Hannequin D., Verpillat P., Brice A., Frebourg T., Campion D. Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. Neurosci. Lett. 328:2002;121-123.
5. Chapman J., Estupinan J., Asherow A. A simple and efficient method for apolipoprotein E genotype determination. Neurology. 46:1996;1484-1485.
6. Chevallier N., Vizzavona J., Marambaud P., Baur C., Spillantini M., Fulcrand P., Martinez J., Goedert M., Vincent J.-P., Checler F. Cathepsin D displays in vitro beta-secretase-like specificity. Brain Res. 750:1997;11-19.
7. Combarros O., Infante J., Llorca J., Pena N., Fernandez-Viadero C., Berciano J. The myeloperoxidase gene in Alzheimer's disease: a case-control study and meta-analysis. Neurosci. Lett. 326:2002;33-36.
8. Crawford F., Freeman M.J., Schinka J., Abdullah L., Richards D., Sevush S., Duara R., Mullan M.J. The genetic association between cathepsin D and Alzheimer's disease. Neurosci. Lett. 289:2000;61-65.
9. Crawford F., Freeman M.J., Schinka J., Morrs M.D., Abdullah L., Richards D., Sevush S., Duara R., Mullan M.J. Association between Alzheimer's disease and a functional polymorphism in the myeloperoxidase gene. Exp. Neurol. 167:2001;456-459.
10. Crawford F., Town T., Freeman M.J., Schinka J., Gold M., Duara R., Mullan M.J. The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample. Neurosci. Lett. 270:1999;133-136.
11. Dahiyat M., Cumming A., Harrington C., Wischik C., Xuereb J., Corrigan F., Breen G., Shaw D., St Clair D. Association between Alzheimer's disease and the NOS3 gene. Ann. Neurol. 46:1999;664-667.
12. Gibson A., Singleton A., Smith G., Woodward R., McKeith I.G., Perry R.H., Ince P.G., Ballard C.G., Edwardson J.A., Morris C.M. Lack of association of the alpha2-macroglobulin locus on chromosome 12 in AD. Neurology. 54:2000;433-438.
13. Hughes S., Khorkova O., Goyal S., Knaeblein J., Heroux J., Riedel N., Sahasrabudhe S. Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation. Proc. Natl. Acad. Sci. USA. 95:1998;3275-3280.
14. Koster M.N., Dermaut B., Cruts M., Houwing-Duistermaat J., Roks G., Tol J., Ott A., Hofman A., Munteanu G., Breteler M., Van Duijn C., Van Broeckhoven C. The alpha2-macroglobulin gene in AD. A population based study and meta-analysis. Neurology. 55:2000;678-684.
15. Kunugi H., Akahane A., Ueki A., Otsuka M., Isse K., Hirasawa H., Kato N., Nabika T., Kobayashi S., Nanko S. No evidence for an association between the Glu298Asp polymorphism of the NOS3 gene and Alzheimer's disease. J. Neural Transm. 107:2000;1081-1084.
16. Liao A., Nitsch R., Greenberg S., Finckh U., Blacker D., Albert M., Rebeck G.W., Gomez-Isla T., Clatworthy A., Binetti G., Hock C., Mueller-Thomsen T., Mann U., Zuchowski K., Beisiegel U., Staehelin H., Growdon J.H., Tanzi R.E., Hyman B.T. Genetic association of an alpha2-macroglobulin (Val1000Ile) polymorphism and Alzheimer's disease. Hum. Mol. Genet. 7:1998;1953-1956.
17. Papassotiropoulos A., Bagli M., Feder O., Jessen F., Maier W., Rao M., Ludwig M., Schwab S., Heun R. Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease. Neurosci. Lett. 262:1999;171-174.
18. Pericak-Vance M.A., Bass M.P., Yamaoka L., Gaskell P.C., Scott W.K., Terwed H.A., Menold M.M., Conneally P.M., Small G.W., Vance J.M., Saunders A.M., Ros A.D., Haines J.L. Complete genomic screen in late-onset familial Alzheimer's disease. Evidence for a new locus on chromosome 12. J. Am. Med. Assoc. 278:1997;1237-1242.
19. Reynolds W.F., Hiltunen M., Pirskanen M., Mannermaa A., Helisalmi S., Lehtovirta M., Alafuzoff I., Soininen H. MPO and APOEepsilon4 polymorphisms interact to increase risk for AD in Finnish males. Neurology. 55:2000;1284-1290.
20. Reynolds W.F., Rhees J., Maciejewski D., Paladino T., Sieburg H., Maki R.A., Masliah E. Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. Exp. Neurol. 155:1999;31-41.
21. Saunders A.M., Strittmatter W.J., Schmechel D., George-Hyslop P.H., Pericak-Vance M.A., Joo S.H., Gusella J.F., Crapper-MacLachlan D.R., Alberts M.J. Association of apolipoprotein E allele e4 with late-onset Alzheimer's disease. Neurology. 43:1993;1467-1472.