ENaC Degradation in A6 Cells by the Ubiquitin-Proteosome Proteolytic Pathway

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12903-12910

  Malik, Bela ^a,b   Schlanger, Lynn ^a   Al Khalili, Otor ^a   Bao, Hui Fang ^a   Yue, Guichun ^a   Price, Stephen Russ ^a   Mitch, William E ^a   Eaton, Douglas Charles ^a  

^a EMORY UNIVERSITY   (United States)

^b Dept of Physiology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; BIOLOGICAL ORGANS; POSITIVE IONS; PROTEINS; SALTS; SODIUM;

MUTATIONS;

CELLS;

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELL PROTEIN; NEURAL PRECURSOR CELL EXPRESSED DEVELOPMENTALLY DOWN REGULATED PROTEIN; PROLINE; PROTEASOME; PROTEIN SUBUNIT; SODIUM CHANNEL; UBIQUITIN; UNCLASSIFIED DRUG; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; EPITHELIAL SODIUM CHANNEL; LEUPEPTIN; MULTIENZYME COMPLEX; PEPTIDE FRAGMENT;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; GENE CONTROL; GENE MUTATION; KIDNEY CELL; LIDDLE SYNDROME; LYSOSOME; MEMBRANE CURRENT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; SODIUM TRANSPORT; WESTERN BLOTTING; XENOPUS; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENETICS; HUMAN; IMMUNOLOGY; KINETICS; METABOLISM; MOLECULAR GENETICS; NEPHRON; PHYSIOLOGY; UROTHELIUM; XENOPUS LAEVIS;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY SPECIFICITY; CELL LINE; CELL MEMBRANE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; EPITHELIAL SODIUM CHANNEL; HUMANS; KINETICS; LEUPEPTINS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NEPHRONS; PEPTIDE FRAGMENTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; SODIUM CHANNELS; UBIQUITINS; UROTHELIUM; XENOPUS LAEVIS;

EID: 0035918146     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010626200     Document Type: Article

References (28)

1. O'Brodovich, H. (1995) New Horizons 3, 240-247
2. Canessa, C. M., Schild, L., Buell, G., Thorens, B., Gautschi, I., Horisberger, J. D., and Rossier, B. C. (1994) Nature 367, 463-467
3. Snyder, P. M., McDonald, F. J., Stokes, J. B., and Welsh, M. J. (1994) J. Biol. Chem. 269, 24379-24383
4. Marunaka, Y., and Eaton, D. C. (1991) Am. J. Physiol. 260, C1071-C1084
5. Staub, O., Gautschi, I., Ishikawa, T., Breitschopf, K., Ciechanover, A., Schild, L., and Rotin, D. (1997) EMBO J. 16, 6325-6336
6. Abriel, H., Loffing, J., Rebhun, J. F., Pratt, J. H., Schild, L., Horisberger, J. D., Rotin, D., and Staub, O. (1999) J. Clin. Invest. 103, 667-673
7. Goulet, C. C., Volk, K. A., Adams, C. M., Prince, L. S., Stokes, J. B., and Snyder, P. M. (1998) J. Biol. Chem. 273, 30012-30017
8. Mitch, W. E., and Goldberg, A. L. (1996) N. Engl. J. Med. 335, 1897-1905
9. Coux, O., Tanaka, K., and Goldberg, A. L. A. L. (1996) Annu. Rev. Biochem. 65, 801-847
10. Ward, C. L., Omura, S., and Kopito, R. R. (1995) Cell 83, 121-127
11. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
12. Staub, O., and Rotin, D. (1996) Structure 4, 495-499
13. Staub, O., Yeger, H., Plant, P. J., Kim, H., Ernst, S. A., and Rotin, D. (1997) Am. J. Physiol. 272, C1871-C1880
14. Harvey, K. F., Dinudom, A., Komwatana, P., Jolliffe, C. N., Day, M. L., Parasivarum, G., Cook, D. I., and Kumar, S. (1999) J. Biol. Chem. 274, 12525-12530
15. Staub, O., Dho, S., Henry, P., Correa, J., Ishikawa, T., McGlade, J., and Rotin, D. (1996) EMBO J. 15, 2371-2380
16. Strous, G. J., and Gowen, C. W. (1999) J. Cell. Sci. 112, 1417-1423
17. Eaton, D. C., Marunaka, Y., and Ling, B. N. (1991) in Membrane Transport in Biology, (Schafer, J., and Giebisch, G. H., eds) pp. 73-165, Springer-Verlag New York Inc. New York
18. Franch, H. A., Curtis, P. V., and Mitch, W. E. (1997) Am. J. Physiol. 273, C843-C851
19. Aniento, F., Roche, E., Cuerve, A. M., and Knepel, W. (1993) J. Biol. Chem. 268, 10463-10470
20. Hamilton, K. L., and Eaton, D. C. (1985) Am. J. Physiol. 249, C200-C207
21. Seglen, P. O. (1983) Methods Enzymol. 96, 737-764
22. Hansson, J. H., Nelson-Williams, C., Suzuki, H., Schild, L., Shimkets, R., Lu, Y., Canessa, C. M., Iwasaki, T., Rossier, B., and Lifton, R. P. (1995) Nat. Genet. 11, 76-82
23. Hansson, J. H., Schild, L., Lu, Y., Wilson, T. A., Gautschi, I., Shimkets, R., Nelson-Williams, C., Rossier, B. C., and Lifton, R. P. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11495-11499
24. Shimkets, R. A., Warnock, D. G., Bositis, C. M., Nelson-Williams, C., Hansson, J. H., Schambelan, M., Gill, J. R., Jr., Ulick, S., Milora, R. V., Findling, J. W., Canessa, C. M., Rossier, B. C., and Lifton, R. P. (1994) Cell 79, 407-414
25. Galan, J. M., Moreau, V., Andre, B., Volland, C., and Hague-nauer-Tsapis, R. (1996) J. Biol. Chem. 271, 10946-10952
26. Egner, R., and Kuchler, K. (1996) FEBS Lett. 378, 177-181
27. Kolling, R., and Hollenberg, C. P. (1994) EMBO J. 13, 3261-3271
28. Berdiev, B. K., Shlyonsky, V. G., Karlson, K. H., Stanton, B. A., and Ismailov, I. I. (2000) Biophys. J. 78, 1881-1894