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Volumn 27, Issue 4, 2005, Pages 321-328

Twenty years of progress in biogerontology research

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; HELICASE; LAMIN A; PROTEIN KU86; PROTEIN P53; TELOMERASE; UNCLASSIFIED DRUG;

EID: 33745636565     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-005-4556-8     Document Type: Review
Times cited : (2)

References (69)
  • 1
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants and aging
    • Balaban RS, Nemoto S and Finkel T (2005) Mitochondria, oxidants and aging. Cell 120: 473-482
    • (2005) Cell , vol.120 , pp. 473-482
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 2
    • 4544322045 scopus 로고    scopus 로고
    • Free radicals and aging
    • Barja G (2004) Free radicals and aging. Trends Neurosci 27: 595-600
    • (2004) Trends Neurosci , vol.27 , pp. 595-600
    • Barja, G.1
  • 3
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM and DePinho RA et al. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91: 25-34
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.A.1    Lee, H.W.2    Hande, M.P.3    Samper, E.4    Lansdorp, P.M.5    DePinho, R.A.6
  • 4
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • Bodnar AG, Oullette M, Frolkis M, Holt SE, Chiu CP and Morin GB et al. (1998) Extension of life-span by introduction of telomerase into normal human cells. Science 279: 349-352
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1    Oullette, M.2    Frolkis, M.3    Holt, S.E.4    Chiu, C.P.5    Morin, G.B.6
  • 6
    • 0037238101 scopus 로고    scopus 로고
    • Cellular senescence and apoptosis: How cellular responses might influence aging phenotypes
    • Campisi J (2002) Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes. Exp Gerontol 38: 5-11
    • (2002) Exp Gerontol , vol.38 , pp. 5-11
    • Campisi, J.1
  • 7
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 9
    • 13944283022 scopus 로고    scopus 로고
    • Longevity and lineages: Toward the integrative biology of degenerative diseases in heart, muscle and bone
    • Chien KR and Karsenty G (2005) Longevity and lineages: toward the integrative biology of degenerative diseases in heart, muscle and bone. Cell 120: 533-544
    • (2005) Cell , vol.120 , pp. 533-544
    • Chien, K.R.1    Karsenty, G.2
  • 10
    • 0035815414 scopus 로고    scopus 로고
    • Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
    • Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H and Hafen E et al. (2001) Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292: 104-107
    • (2001) Science , vol.292 , pp. 104-107
    • Clancy, D.J.1    Gems, D.2    Harshman, L.G.3    Oldham, S.4    Stocker, H.5    Hafen, E.6
  • 11
    • 0034455827 scopus 로고    scopus 로고
    • Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
    • Coschigano KT, Clemmons D, Bellush LL and Kopchick JJ (2000) Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 141: 2608-2613
    • (2000) Endocrinology , vol.141 , pp. 2608-2613
    • Coschigano, K.T.1    Clemmons, D.2    Bellush, L.L.3    Kopchick, J.J.4
  • 12
    • 21644484769 scopus 로고    scopus 로고
    • How much can human life span be extended
    • Couzin J (2005) How much can human life span be extended. Science 309: 83
    • (2005) Science , vol.309 , pp. 83
    • Couzin, J.1
  • 14
    • 0029047362 scopus 로고
    • A novel biomarker identifies senescent human cells in culture and aging skin in vivo
    • USA
    • Dimri GP, Lee X, Basile G, Acosta M, Scott G and Roskelley C et al. (1995) A novel biomarker identifies senescent human cells in culture and aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3    Acosta, M.4    Scott, G.5    Roskelley, C.6
  • 15
    • 0037673950 scopus 로고    scopus 로고
    • Recurrent de novo point mutations in Lamin a cause Hutchison-Gilford progeria syndrome
    • Eriksson M, Brown TW, Gordon LB, Glynn MW, Singer J and Scott L et al. (2003) Recurrent de novo point mutations in Lamin A cause Hutchison-Gilford progeria syndrome. Nature 423: 293-298
    • (2003) Nature , vol.423 , pp. 293-298
    • Eriksson, M.1    Brown, T.W.2    Gordon, L.B.3    Glynn, M.W.4    Singer, J.5    Scott, L.6
  • 16
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • Friedman DB and Johnson TE (1988) A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118: 75-86
    • (1988) Genetics , vol.118 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 17
    • 0030977793 scopus 로고    scopus 로고
    • Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein
    • Friguet B and Szweda LL (1997) Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein. FEBS Lett 405: 21-25
    • (1997) FEBS Lett , vol.405 , pp. 21-25
    • Friguet, B.1    Szweda, L.L.2
  • 18
    • 2942643923 scopus 로고    scopus 로고
    • Accumulation of mutant lamin a causes progressive changes in nuclear structure in Hutchinson-Gilford progeria syndrome
    • USA
    • Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE and Gordon LB et al. (2004) Accumulation of mutant lamin A causes progressive changes in nuclear structure in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci USA 101: 8963-8968
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 8963-8968
    • Goldman, R.D.1    Shumaker, D.K.2    Erdos, M.R.3    Eriksson, M.4    Goldman, A.E.5    Gordon, L.B.6
  • 20
    • 13944253348 scopus 로고    scopus 로고
    • Calorie restriction - The SIR2 connection
    • Guarente L and Picard F (2005) Calorie restriction - the SIR2 connection. Cell 120: 473-482
    • (2005) Cell , vol.120 , pp. 473-482
    • Guarente, L.1    Picard, F.2
  • 21
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB and Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 22
    • 77049308856 scopus 로고
    • A theory based on free radical and radiation chemistry
    • Harman D (1956) A theory based on free radical and radiation chemistry. J Gerontol 11: 298-300
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 23
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1-cyclin dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1-cyclin dependent kinases. Cell 75: 805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 24
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37: 614-636
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 26
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz KI, Bitterman KJ, Cohen HY, Lamming DW, Lavu S and Wood JG et al. (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425: 191-196
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.I.1    Bitterman, K.J.2    Cohen, H.Y.3    Lamming, D.W.4    Lavu, S.5    Wood, J.G.6
  • 27
    • 0345237923 scopus 로고    scopus 로고
    • Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: Correlation to extended longevity
    • Ikeno Y, Bronson RT, Hubbard GB, Lee S and Bartke A (2002) Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: correlation to extended longevity. J Gerontol 58: 291-296
    • (2002) J Gerontol , vol.58 , pp. 291-296
    • Ikeno, Y.1    Bronson, R.T.2    Hubbard, G.B.3    Lee, S.4    Bartke, A.5
  • 28
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura KD, Tissenbaum HA, Liu X and Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, X.3    Ruvkun, G.4
  • 29
    • 0036829090 scopus 로고    scopus 로고
    • Cancer and aging: A model for the cancer promoting effects of aging stroma
    • Krtolica A and Campisi J (2002) Cancer and aging: a model for the cancer promoting effects of aging stroma. Int J Biochem Cell Biol 34: 1401-1414
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1401-1414
    • Krtolica, A.1    Campisi, J.2
  • 30
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
    • USA
    • Krtolica A, Parrinello S, Lockett S, Desprez PY and Campisi J (2001) Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci USA 98: 12072-12077
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5
  • 31
    • 22344456832 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations, oxidative stress and apoptosis in mammalian aging
    • Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K and Wohlgemuth SE et al. (2005) Mitochondrial DNA mutations, oxidative stress and apoptosis in mammalian aging. Science 309: 481-484
    • (2005) Science , vol.309 , pp. 481-484
    • Kujoth, G.C.1    Hiona, A.2    Pugh, T.D.3    Someya, S.4    Panzer, K.5    Wohlgemuth, S.E.6
  • 32
    • 0037112338 scopus 로고    scopus 로고
    • Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury
    • LaBarge MA and Blau HM (2002) Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury. Cell 111: 589-601
    • (2002) Cell , vol.111 , pp. 589-601
    • LaBarge, M.A.1    Blau, H.M.2
  • 33
    • 0027515616 scopus 로고
    • Aging and resistance to oxidative stress in Caenorhabditis elegans
    • USA
    • Larsen P (1993) Aging and resistance to oxidative stress in Caenorhabditis elegans. Proc Natl Acad Sci USA 90: 8905-8909
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 8905-8909
    • Larsen, P.1
  • 34
    • 0000977248 scopus 로고
    • Selection for delayed senescence in Drosophila melanogaster
    • Luckinbill L, Arking R and Clare M (1984) Selection for delayed senescence in Drosophila melanogaster. Evolution 38: 996-1003
    • (1984) Evolution , vol.38 , pp. 996-1003
    • Luckinbill, L.1    Arking, R.2    Clare, M.3
  • 36
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life span and upon ultimate body size
    • McCay CM, Crowell MF and Maynard LA (1935) The effect of retarded growth upon the length of life span and upon ultimate body size. J Nutr 10: 63-79
    • (1935) J Nutr , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 37
    • 0033581704 scopus 로고    scopus 로고
    • The p66shc adaptor protein controls oxidative stress response and life span in mammals
    • Miggliaccio E, Giorgio M, Mele S, Pelicci G, Reholdi P and Pandolfi PP et al. (1999) The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402: 309-313
    • (1999) Nature , vol.402 , pp. 309-313
    • Miggliaccio, E.1    Giorgio, M.2    Mele, S.3    Pelicci, G.4    Reholdi, P.5    Pandolfi, P.P.6
  • 38
    • 0031003513 scopus 로고    scopus 로고
    • Transgenic mice over-expressing urokinase-type plasminogen activator in brain exhibit reduced food consumption, body weight and increased longevity
    • Mishkin R and Masos T (1997) Transgenic mice over-expressing urokinase-type plasminogen activator in brain exhibit reduced food consumption, body weight and increased longevity. J Gerontol 52: B118-B124
    • (1997) J Gerontol , vol.52
    • Mishkin, R.1    Masos, T.2
  • 39
    • 0033518188 scopus 로고    scopus 로고
    • A telomerase component defective in the human disease dyskeratosis congenita
    • Mitchell JR, Wood E and Collins K (1999) A telomerase component defective in the human disease dyskeratosis congenita. Nature 402: 551-555
    • (1999) Nature , vol.402 , pp. 551-555
    • Mitchell, J.R.1    Wood, E.2    Collins, K.3
  • 40
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • Morris J, Tissenbaum H and Ruvkun G (1996) A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382: 536-539
    • (1996) Nature , vol.382 , pp. 536-539
    • Morris, J.1    Tissenbaum, H.2    Ruvkun, G.3
  • 41
    • 0037673940 scopus 로고    scopus 로고
    • A progeroid syndrome in mice is caused by defects in the A-type lamins
    • Mounkes LC, Kozlov S, Hernandez L, Sullivan T and Stewart CL (2003) A progeroid syndrome in mice is caused by defects in the A-type lamins. Nature 423: 298-301
    • (2003) Nature , vol.423 , pp. 298-301
    • Mounkes, L.C.1    Kozlov, S.2    Hernandez, L.3    Sullivan, T.4    Stewart, C.L.5
  • 42
    • 13244287677 scopus 로고    scopus 로고
    • Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche
    • Nishimura EK, Granter SR and Fisher DE (2005) Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science 307: 720-724
    • (2005) Science , vol.307 , pp. 720-724
    • Nishimura, E.K.1    Granter, S.R.2    Fisher, D.E.3
  • 43
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda A, Yi N, Venable SF, Pereira-Smith OM and Smith JR (1994) Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211: 90-98
    • (1994) Exp Cell Res , vol.211 , pp. 90-98
    • Noda, A.1    Yi, N.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 44
    • 17944371854 scopus 로고    scopus 로고
    • Mobilized bone marrow cells repair the infarcted heart, improving function and survival
    • USA
    • Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I and Quaini F et al. (2001) Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 98: 10344-10349
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 10344-10349
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3    Limana, F.4    Jakoniuk, I.5    Quaini, F.6
  • 45
    • 0000977247 scopus 로고
    • Laboratory evolution of postponed senescence in Drosophila melanogaster
    • Rose MR (1984) Laboratory evolution of postponed senescence in Drosophila melanogaster. Evolution 38: 1004-1010
    • (1984) Evolution , vol.38 , pp. 1004-1010
    • Rose, M.R.1
  • 46
    • 0033525558 scopus 로고    scopus 로고
    • Longevity, stress response, and cancer in aging telomerase-deficient mice
    • Rudolph KL, Chang S, Lee HW, Blasco M, Gottlieb GJ and Greider C et al. (1999) Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96: 701-712
    • (1999) Cell , vol.96 , pp. 701-712
    • Rudolph, K.L.1    Chang, S.2    Lee, H.W.3    Blasco, M.4    Gottlieb, G.J.5    Greider, C.6
  • 47
    • 0042344907 scopus 로고    scopus 로고
    • Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts
    • Sampaolesi M, Torrente Y, Innocenzi A, Tontorenzi R, D'Antona G and Pellogrino MA et al. (2003) Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 301: 487-491
    • (2003) Science , vol.301 , pp. 487-491
    • Sampaolesi, M.1    Torrente, Y.2    Innocenzi, A.3    Tontorenzi, R.4    D'Antona, G.5    Pellogrino, M.A.6
  • 48
  • 49
    • 0025052004 scopus 로고
    • c-fos repression and an altered genetic program in senescent human fibroblasts
    • Seshadri T and Campisi J (1990) c-fos repression and an altered genetic program in senescent human fibroblasts. Science 247: 205-209
    • (1990) Science , vol.247 , pp. 205-209
    • Seshadri, T.1    Campisi, J.2
  • 50
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases -2, -3, -6, -7, -8 and -10 in a caspase-9- Dependent manner
    • Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA and Newmeyer DD et al. (1999) Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases -2, -3, -6, -7, -8 and -10 in a caspase-9- dependent manner. J Cell Biol 144: 281-292
    • (1999) J Cell Biol , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3    Wolf, B.B.4    Casiano, C.A.5    Newmeyer, D.D.6
  • 51
    • 2342535103 scopus 로고    scopus 로고
    • Cord-blood transplants from unrelated donors in patients with Hurler's syndrome
    • Staba SL, Escolar ML, Poe M, Kim Y, Martin PL and Szabolcs P et al. (2004) Cord-blood transplants from unrelated donors in patients with Hurler's syndrome. N Eng J Med 350: 1960-1969
    • (2004) N Eng J Med , vol.350 , pp. 1960-1969
    • Staba, S.L.1    Escolar, M.L.2    Poe, M.3    Kim, Y.4    Martin, P.L.5    Szabolcs, P.6
  • 52
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • Tatar M, Kopelmann A, Epstein D, Tu M-P, Yin C-M and Garofalo RS (2001) A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292: 107-110
    • (2001) Science , vol.292 , pp. 107-110
    • Tatar, M.1    Kopelmann, A.2    Epstein, D.3    Tu, M.-P.4    Yin, C.-M.5    Garofalo, R.S.6
  • 53
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum HA and Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227-230
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 56
    • 12144288373 scopus 로고    scopus 로고
    • Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
    • Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N and Thorpe SR et al. (2003) Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics 16: 29-37
    • (2003) Physiol Genomics , vol.16 , pp. 29-37
    • Van Remmen, H.1    Ikeno, Y.2    Hamilton, M.3    Pahlavani, M.4    Wolf, N.5    Thorpe, S.R.6
  • 57
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B, Smogorzewska A and de Lange T (1998) TRF2 protects human telomeres from end-to-end fusions. Cell 92: 401-413
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 59
    • 11144308949 scopus 로고    scopus 로고
    • Longevity genes: From primitive organisms to humans
    • Warner HR (2005) Longevity genes: from primitive organisms to humans. Mech Ageing Dev 126: 235-242
    • (2005) Mech Ageing Dev , vol.126 , pp. 235-242
    • Warner, H.R.1
  • 60
    • 0037726549 scopus 로고    scopus 로고
    • Models of accelerated aging can be informative about the molecular mechanisms of ageing and/ or age-related pathology
    • Warner HR and Sierra F (2003) Models of accelerated aging can be informative about the molecular mechanisms of ageing and/ or age-related pathology. Mech Ageing Dev 124: 581-587
    • (2003) Mech Ageing Dev , vol.124 , pp. 581-587
    • Warner, H.R.1    Sierra, F.2
  • 61
    • 0030765215 scopus 로고    scopus 로고
    • What does cell death have to do with aging?
    • Warner HR, Hodes RJ and Pocinki K (1997) What does cell death have to do with aging? J Am Geriatr Soc 45: 1140-1146
    • (1997) J Am Geriatr Soc , vol.45 , pp. 1140-1146
    • Warner, H.R.1    Hodes, R.J.2    Pocinki, K.3
  • 64
    • 0032573066 scopus 로고    scopus 로고
    • Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
    • USA
    • Yan L-J and Sohal RS (1998) Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc Natl Acad Sci USA 95: 12896-12901
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 12896-12901
    • Yan, L.-J.1    Sohal, R.S.2
  • 65
    • 0030881686 scopus 로고    scopus 로고
    • Oxidative damage during aging targets mitochondrial aconitase
    • USA
    • Yan L-J, Levine RL and Sohal RS (1997) Oxidative damage during aging targets mitochondrial aconitase. Proc Natl Acad Sci USA 94: 11168-11172
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 11168-11172
    • Yan, L.-J.1    Levine, R.L.2    Sohal, R.S.3
  • 66
    • 0029759443 scopus 로고    scopus 로고
    • Aging and oxidative stress: Modulation by dietary restriction
    • Yu BP (1996) Aging and oxidative stress: modulation by dietary restriction. Free Radic Biol Med 21: 651-668
    • (1996) Free Radic Biol Med , vol.21 , pp. 651-668
    • Yu, B.P.1
  • 67
    • 0025255636 scopus 로고
    • The Caenorhabditis elegans genes ced-3 and ced-4 act autonomously to cause programmed cell death
    • Yuan J and Horvitz HR (1990) The Caenorhabditis elegans genes ced-3 and ced-4 act autonomously to cause programmed cell death. Dev Biol 138: 33-41
    • (1990) Dev Biol , vol.138 , pp. 33-41
    • Yuan, J.1    Horvitz, H.R.2
  • 68
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 gene codes for a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM and Horvitz HR (1993) The C. elegans cell death gene ced-3 gene codes for a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75: 641-652
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.