The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission

Journal of Cell Biology

Volumn 158, Issue 3, 2002, Pages 445-452

  Tieu, Quinton ^a   Okreglak, Voytek ^a   Naylor, Kari ^a   Nunnari, Jodi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dynamin related GTPase; Fission; Membranes; Mitochondria; WD repeat

Indexed keywords

ADAPTOR PROTEIN; PROTEIN DNM1P; PROTEIN FIS1P; PROTEIN MDV1P; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; CATALYSIS; COMPLEX FORMATION; FUNCTION TEST; HYBRIDIZATION; MEMBRANE FUSION; MITOCHONDRIAL MEMBRANE; MOLECULAR INTERACTION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS MODEL; PROCESS MONITORING; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN INTERACTION; REGULATORY MECHANISM; STRUCTURE ANALYSIS;

CARRIER PROTEINS; CELL COMPARTMENTATION; CELL DIVISION; CYTOSOL; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GTP PHOSPHOHYDROLASES; INTEGRATION HOST FACTORS; INTRACELLULAR MEMBRANES; MACROMOLECULAR SUBSTANCES; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

ACTINOBACTERIA (CLASS); FUNGI; UNCULTURED ACTINOMYCETE;

EID: 0036322806     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200205031     Document Type: Article

References (21)

1. The dynamin-related GTPases, Dnm1, regulates mitochondrial fission in yeast
2. Division of mitochondria requires a novel DNM1-interacting protein, Net2p
3. Gag3p, an outer membrane protein required for fission of mitochondrial tubules
4. The AH/GED sequence of the dnmlp GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fission
5. Applications of high efficiency lithium acetate transformation of intact yeast cells using single-stranded nucleic acids as carrier
6. Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase
7. Immunoaffinity purification
8. Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p
9. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
10. C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane
11. Dnmlp GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p
12. Mitochondrial transmission during mating in S. cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mtDNA
13. The dynamin GTPase, Dnm1p, controls mitochondrial morphology in yeast
14. Fzolp is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae
15. Control of mitochondrial morphology by a human mitofusin
16. Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape
17. Mitochondrial dynamics and division in budding yeast
18. A human dynamin-related protein controls the distribution of mitochondria
19. Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division
20. MultiCoil: A program for predicting two-and three-stranded coiled coils