Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 26, 2000, Pages 14461-14466

  Sligh, James E ^a   Levy, Shawn E ^a   Waymire, Katrina G ^a   Allard, Paulette ^a   Dillehay, Dirck L ^a   Nusinowitz, Steven ^b   Heckenlively, John R ^b   MacGregor, Grant R ^a   Wallace, Douglas C ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JULES STEIN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL LINEAGE; CHIMERA; CONGENITAL CATARACT; CYTOPLASM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE MUTATION; GERM LINE; HEART DILATATION; HYBRID CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ANIMALS; BRAIN; CELL LINE; CHIMERA; CHLORAMPHENICOL; CONES (RETINA); DNA, MITOCHONDRIAL; DRUG RESISTANCE; FEMALE; GENOMIC IMPRINTING; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; MYOCARDIUM; OVUM; PEDIGREE; PHENOTYPE; RODS (RETINA); STEM CELLS;

EID: 0034687797     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.250491597     Document Type: Article

References (41)

1. Li, Y., Huang, T. T., Carlson, E. J., Melov, S., Ursell, P. C., Olson, J. L., Noble, L. J., Yoshimura, M. P., Berger, C., Chan, P. H., et al. (1995) Nat. Genet. 11, 376-381.
2. Graham, B., Waymire, K., Cottrell, B., Trounce, I. A., MacGregor, G. R. & Wallace, D. C. (1997) Nat. Genet. 16, 226-234.
3. Melov, S., Schneider, J. A., Day, B. J., Hinerfeld, D., Coskun, P., Mirra, S. S., Crapo, J. D. & Wallace, D. C. (1998) Nat. Genet. 18, 159-163.
4. Melov, S., Coskun, P., Patel, M., Tunistra, R., Cottrell, B., Jun, A. S., Zastawny, T. H., Dizdaroglu, M., Goodman, S. I., Huang, T., et al. (1999) Proc. Natl. Acad. Sci. USA 96, 846-851.
5. Esposito, L. A., Kokoszka, J. E., Waymire, K. G., Cottrell, B., MacGregor, G. R. & Wallace, D. C. (2000) Free Radical Biol. Med. 28, 754-766.
6. Larsson, N. G., Wang, J., Wilhelmsson, H., Oldfors, A., Rustin, P., Lewandoski, M., Barsh, G. S. & Clayton, D. A. (1998) Nat. Genet. 18, 231-236.
7. Wallace, D. C. (1999) Science 283, 1482-1488.
8. Wallace, D. C., Brown, M. D. & Lott, M. T. (1996) in Emery and Rimoin's Principles and Practice of Medical Genetics, eds. Rimoin, D. L., Connor, J. M., Pyeritz, R. E. & Emery, A. E. H. (Churchill Livingstone, London), Vol. 1, pp. 277-332.
9. Blanc, H., Adams, C. W. & Wallace, D. C. (1981) Nucleic Acids Res. 9, 5785-5795.
10. Watanabe, T., Dewey, M. J. & Mintz, B. (1978) Proc. Natl. Acad. Sci. USA 75, 5113-5117.
11. Levy, S. E., Waymire, K. G., Kim, Y. L., MacGregor, G. R. & Wallace, D. C. (1999) Transgenic Res. 8, 137-145.
12. Marchington, D. R., Barlow, D. & Poulton, J. (1999) Nat. Med. 5, 957-960.
13. Bai, Y. & Attardi, G. (1998) EMBO J. 17, 4848-4858.
14. Pinkert, C. A., Irwin, M. H., Johnson, L. W. & Moffatt, R. J. (1997) Transgenic Res. 6, 379-383.
15. Jenuth, J. P., Peterson, A. C., Fu, K. & Shoubridge, E. A. (1996) Nat. Genet. 14, 146-151.
16. Jenuth, J. P., Peterson, A. C. & Shoubridge, E. A. (1997) Nat. Genet. 16, 93-95.
17. Inoue, K., Nakada, K., Oeura, A., Isobe, K., Goto, Y., Nonaka, I. & Hayashi, J.-I. (2000) Nat. Genet. 26, 176-181.
18. McMahon, A. P. & Bradley, A. (1990) Cell 62, 1073-1085.
19. Trounce, I., Schmiedel, J., Yen, H. C., Hosseini, S., Brown, M. D., Olson, J. J. & Wallace, D. C. (2000) Nucleic Acids Res. 28, 2164-2170.
20. Bunn, C. L., Wallace, D. C. & Eisenstadt, J. M. (1974) Proc. Natl. Acad. Sci. USA 71, 1681-1685.
21. Stocco, D. M. (1983) Anal. Biochem. 131, 453-457.
22. Bradley, A. (1987) in Teratocarcinomas and Embryonic Stem Cells. A Practical Approach, ed. Robertson, E. J. (IRL Press, Oxford), pp. 113-151.
23. Trounce, I. & Wallace, D. C. (1996) Somat. Cell Mol. Genet. 22, 81-85.
24. Akhmedov, N. B., Piriev, N. I., Chang, B., Rapoport, A. L., Hawes, N. L. Nishina, P. M. Nusinowitz, S., Heckenlively, J. R., Roderick, T. H., Kozak, C. A., et al. (2000) Proc. Natl. Acad. Sci. USA 97, 5551-5556.
25. Ferris, S. D. Sage, R. D. & Wilson, A. C. (1982) Nature (London) 295, 163-165.
26. Koopman, P., Gubbay, J., Vivian, N., Goodfellow, P. & Lovell-Badge, R. (1991) Nature (London) 351, 117-121.
27. Gear, A. R. (1974) J. Biol. Chem. 249, 3628-3637.
28. Ramirez-Solis, R., Rivera-Perez, J., Wallace, J. D., Wims, M., Zheng, H. & Bradley, A. (1992) Anal. Biochem. 201, 331-335.
29. Chang, B., Hawes, N. L., Roderick, T. H., Smith, R. S., Heckenlively, J. R., Horwitz. J. & Davisson, M. T. (1999) Mol. Vis. 5, 21.
30. Smith, R. S., Hawes, N. L., Chang, B., Roderick, T. H., Akeson, E. C., Heckenlively, J. R., Gong, X., Wang, X. & Davisson, M. T. (2000) Genomics 63, 314-320.
31. Ota, Y., Miyake, Y., Awaya, S., Kumagai, T., Tanaka, M. & Ozawa, T. (1194) Retina 14, 270-276.
32. Ortiz, R. G., Newman, N. J., Shoffner, J. M., Kaufman, A. E., Koontz, D. A. & Wallace, D.C. (1993) Arch. Ophthalmol. 111, 1525-1530.
33. Shoffner, J. M., Bialer, M. G., Pavlakis, S. G., Lott, M. T., Kaufman, A., Dixon, J., Teichberg, S. & Wallace, D. C. (1995) Neurology 45, 286-292.
34. McAvoy, J. W., Chamberlain, C. G., de Iongh, R. U., Hales, A. M. & Lovicu, F. J. (1999) Eye 13, 425-437.
35. Chowers, I., Lerman-Sagie, T., Elpeleg, O. N., Shaag, A. & Merin, S. (1999) Br. J. Ophthalmol. 83, 190-193.
36. Heddi, A., Stepien, G., Benke, P. J. & Wallace, D. C. (1999) J. Biol. Chem. 274, 22968-22976.
37. Howell, N., Bantel, A. & Huang, P. (1983) Somatic Cell Genet. 9, 721-743.
38. Howell, N., Huang, P., Kelliher, K. & Ryan, M. L. (1983) Somatic Cell Genet. 9, 143-163.
39. Howell, N., Appel, J., Cook, J. P., Howell, B. & Hauswirth, W. W. (1987) J. Biol. Chem. 262, 2411-2414.
40. Howell, N. & Gilbert, K. (1988) J. Mol. Biol. 203, 607-618.
41. Howell, N. (1990) Biochemistry 29, 8970-8977.