Recombination of Human Mitochondrial DNA

Science

Volumn 304, Issue 5673, 2004, Pages 981-

  Kraytsberg, Yevgenya ^a   Schwartz, Marianne ^b   Brown, Timothy A ^c   Ebralidse, Konstantin ^a   Kunz, Wolfram S ^d   Clayton, David A ^c   Vissing, John ^b   Khrapko, Konstantin ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Rigshospitalet   (Denmark)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

RNA;

ARTICLE; CELL DIVISION; CELL FUNCTION; DNA POLYMORPHISM; DNA REPLICATION; HUMAN; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; FATHER; FEMALE; GENETIC RECOMBINATION; GENETICS; MALE; MOTHER; MUSCLE MITOCHONDRION;

DNA REPLICATION; DNA, MITOCHONDRIAL; FATHERS; FEMALE; HUMANS; MALE; MITOCHONDRIA, MUSCLE; MOTHERS; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC;

EID: 2442609784     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1096342     Document Type: Article

References (9)

1. E. Hagelberg, Trends Genet. 19, 84 (2003).
2. A. Rokas, E. Ladoukakis, E. Zouros, Trends Ecol. Evol. 18, 411 (2003).
3. M. Schwartz, J. Vissing, N. Engl. J. Med. 347, 576 (2002).
4. Materials and methods are available as supporting material on Science Online.
5. C. L. Yauk, P. R. Bois, A. J. Jeffreys, EMBO J. 22, 1389 (2003).
6. T. Brown, D. Clayton, in preparation.
7. B. Thyagarajan, R. A. Padua, C. Campbell, J. Biol. Chem. 271, 27536 (1996).
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9. We thank A. de Grey, M. Frank-Kamanetskii, B. Thilly, and anonymous reviewers for their input, and A. Pluzhnikov for help with statistical analysis. Supported in part by NIH grant nos. ES11343, AG19787, and AG18388 (K.K.).