Structure-activity relationships of KATP channel openers

Current Topics in Medicinal Chemistry

Volumn 6, Issue 10, 2006, Pages 1031-1047

  Mannhold, Raimund ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Benzopyrans; Cyanoguanidines; Cyclobutenediones; Diazoxide; Dihydropyridine related structures; KATP channel openers (KCOs); Structure activity relationships; Tertiary carbinols; Thioformamides

Indexed keywords

1 (6,7 DIHYDRO 6 HYDROXY 5,5 DIMETHYL 2 NITRO 5H THIENO[3,2 B]PYRAN 7 YL) 2 PIPERIDINONE; 2 (3,4 DIHYDRO 2,2 DIMETHYL 6 NITRO 2H 1,4 BENZOXAZIN 4 YL)PYRIDINE 1 OXIDE; 2 (6 CYANO 2,2 DIMETHYL 2H 1 BENZOPYRAN 4 YL)PYRIDINE 1 OXIDE; 3,4 DIHYDRO 2,2 DIMETHYL 4 (2 OXO 1 PIPERIDINYL) 6 PENTAFLUOROETHYL 2H 1 BENZOPYRAN 3 OL; 4 (1,2 DIHYDRO 2 OXO 1 PYRIDYL) 1,2 DIHYDRO 2,2 DIMETHYL 1 OXONAPHTHALENE 6 CARBONITRILE; 4 [(1,6 DIHYDRO 1 METHYL 6 OXO 3 PYRIDAZINYL)AMINO] 3 HYDROXY 2,2 BIS(METHOXYMETHYL)CHROMAN 6 CARBONITRILE; 7,8 DIHYDRO 7 HYDROXY 6,6 DIMETHYL 8 (2 OXO 1 PIPERIDYL) 6H PYRANO[2,3 F][2,1,3]BENZOXADIAZOLE; ADENOSINE TRIPHOSPHATE; APRIKALIM; BENZOPYRAN DERIVATIVE; BMS 191095; CIMETIDINE; CROMAKALIM; DIHYDROPYRIDINE DERIVATIVE; FORMAMIDE DERIVATIVE; GLIBENCLAMIDE; GUANIDINE DERIVATIVE; KC 515; LEMAKALIM; METHANOL DERIVATIVE; N (2 CYANOETHYL) 2,2 BIS(FLUOROMETHYL) 6 NITRO 2H 1 BENZOPYRAN 4 CARBOTHIOAMIDE; N (4 CHLOROPHENYL) N' CYANO N'' (6 CYANO 3,4 DIHYDRO 3 HYDROXY 2,2 DIMETHYL 2H 1 BENZOPYRAN 4 YL)GUANIDINE; N METHYL 2 (2 PYRIDYL) 2 TETRAHYDROTHIOPHENECARBOTHIOAMIDE; NITRIC ACID DERIVATIVE; POTASSIUM CHANNEL STIMULATING AGENT; RILMAKALIM; SULFONYLUREA; THIADIAZINE DERIVATIVE; U 96501; UNCLASSIFIED DRUG; UNINDEXED DRUG;

DRUG MECHANISM; DRUG SYNTHESIS; DRUG TARGETING; GENE TARGETING; HYPOTENSION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN FUNCTION; REVIEW; SMOOTH MUSCLE RELAXATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZOPYRANS; CYCLOBUTANES; FORMAMIDES; GUANIDINES; HUMANS; METHANOL; POTASSIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZINES;

EID: 33744474035     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802606777323647     Document Type: Review

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