Cardioselective antiischemic ATP-sensitive potassium channel (K(ATP)) openers. 5. Identification of 4-(N-aryl)-substituted benzopyran derivatives with high selectivity

Journal of Medicinal Chemistry

Volumn 40, Issue 1, 1997, Pages 24-34

  Rovnyak, George C ^a   Ahmed, Syed Z ^a   Ding, Charles Z ^a   Dzwonczyk, Steven ^a   Ferrara, Francis N ^a   Humphreys, W Griffith ^a   Grover, Gary J ^a   Santafianos, Dinos ^a   Atwal, Karnail S ^a   Baird, Anne J ^a   McLaughlin, Lee G ^a   Normandin, Diane E ^a   Sleph, Paul G ^a   Traeger, Sarah C ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [(4 CHLOROPHENYL) N (1H IMIDAZOL 2 YLMETHYL)AMINO] 3,4 DIHYDRO 3 HYDROXY 2,2 DIMETHYL 2H 1 BENZOPYRAN 6 CARBONITRILE; BENZOPYRAN DERIVATIVE; BMS 191095; CROMAKALIM; N (4 CHLOROPHENYL) N' CYANO N'' (6 CYANO 3,4 DIHYDRO 3 HYDROXY 2,2 DIMETHYL 2H 1 BENZOPYRAN 4 YL)GUANIDINE; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; STRUCTURE ACTIVITY RELATION; VASODILATATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BENZOPYRANS; BIOLOGICAL AVAILABILITY; GLYBURIDE; HEART; POTASSIUM CHANNELS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 8044260833     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9605905     Document Type: Article

References (35)

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