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Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 23, 2004, Pages 5727-5730

2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K ATP channels

(6) Nielsen, Flemming E a Jacobsen, Palle a Worsaae, Anne a Arkhammar, Per O G a Wahl, Philip a Bondo Hansen, John a

a NOVO NORDISK A S (Denmark)

Author keywords

Beta cell; Diazoxide; Insulin release; K ATP channels; NN414

Indexed keywords

2 (4 METHOXYPHENOXY) 5 NITRO N (4 SULFAMOYLPHENYL)BENZAMIDE; 2 PHENOXY N (4 METHOXYPHENYL)BENZAMIDE; 4 METHOXYPHENYLAMINOBENZAMIDE; 7 CHLORO 3 ISOPROPYLAMINO 4H 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; BENZAMIDE DERIVATIVE; DIAZOXIDE; GLUCOSE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; NN 414; NNC 55 0557; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; INSULIN RELEASE; PANCREAS ISLET BETA CELL; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BENZAMIDES; BENZOTHIADIAZINES; DIAZOXIDE; ISLETS OF LANGERHANS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRIDINES; RATS; RECEPTORS, DRUG; THIADIAZINES;

EID: 7044247605 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.09.057 Document Type: Article

Times cited : (14)

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