Synthesis and structure-activity relationships of novel phenylcyanoguanidine derivatives as potassium channel openers

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 11, 1996, Pages 2042-2050

  Yoshiizumi, Kazuya ^a   Ikeda, Shoji ^a   Goto, Katsumi ^a   Morita, Tominori ^a   Nishimura, Noriyasu ^a   Sukamoto, Takayuki ^a   Yoshino, Kohichiro ^a  

^a KANEBO LTD   (Japan)

Author keywords

antihypertensive effect; phenylcyanoguanidine; pinacidil; potassium channel opener; smooth muscle relaxation activity

Indexed keywords

GUANIDINE DERIVATIVE; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL AFFECTING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SMOOTH MUSCLE RELAXATION; SPONTANEOUSLY HYPERTENSIVE RAT; STRUCTURE ACTIVITY RELATION;

EID: 0029857426     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.2042     Document Type: Article

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