Highly potent 1,4-benzothiazine derivatives as KATP-channel openers

Journal of Medicinal Chemistry

Volumn 46, Issue 17, 2003, Pages 3670-3679

  Cecchetti, Violetta ^a   Calderone, Vincenzo ^b   Tabarrini, Oriana ^a   Sabatini, Stefano ^a   Filipponi, Enrica ^a   Testai, Lara ^b   Spogli, Roberto ^a   Martinotti, Enrica ^b   Fravolini, Arnaldo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3,4 DIHYDRO 2,2 DIMETHYL 6 NITRO 2H 1,4 BENZOXAZIN 4 YL)PYRIDINE 1 OXIDE; 2,2 DIMETHYL 4 (1 OXO 2 CYCLOPENTEN 2 YL) 6 TRIFUOROMETHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZINE; 2,2 DIMETHYL 6 NITRO 4 (1 OXO 2 CYCLOPENTEN 2 YL) 3,4 DIHYDRO 2H 1,4 BENZOTHIAZINE; 6 CYANO 2,2 DIMETHYL 4 (1 OXO 2 CYCLOPENTEN 2 YL) 3,4 DIHYDRO 2H 1,4 BENZOTHIAZINE; BENZOPYRAN DERIVATIVE; BENZOTHIAZINE DERIVATIVE; CROMAKALIM; CYCLOPENTENONE; FORMAMIDE; GLIBENCLAMIDE; GUANIDINE DERIVATIVE; LEMAKALIM; NICORANDIL; PINACIDIL; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ELECTRON TRANSPORT; MALE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; VASODILATATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; AORTA; ION CHANNEL GATING; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNELS; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZINES; VASODILATOR AGENTS;

EID: 0041731570     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030791q     Document Type: Article

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