N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: K(ATP) potassium channel openers. Modifications on the western region

Journal of Medicinal Chemistry

Volumn 39, Issue 23, 1996, Pages 4592-4601

  Ohnmacht, Cyrus J ^a   Russell, Keith ^a   Empfield, James R ^a   Frank, Cathy A ^a   Gibson, Keith H ^a   Mayhugh, Daniel R ^a   McLaren, Frances M ^a   Shapiro, Howard S ^a   Brown, Frederick J ^a   Trainor, Diane A ^a   Ceccarelli, Christopher ^a   Lin, Margaret M ^a   Masek, Brian B ^a   Forst, Janet M ^a   Harris, Robert J ^a   Hulsizer, James M ^a   Lewis, Joseph J ^a   Silverman, Stuart M ^a   Smith, Reed W ^a   Warwick, Paul J ^a   Kau, Sen T ^a   Chun, Alexa L ^a   Grant, Thomas L ^a   Howe, Burton B ^a   Li, Jack H ^a   Trivedi, Shephali ^a   Halterman, Tracy J ^a   Yochim, Christopher ^a   Dyroff, Martin C ^a   Kirkland, M ^a   Neilson, Kathleen L ^a   more..

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANDROGEN; BICALUTAMIDE; CROMAKALIM; N (4 BENZOYLPHENYL) 3,3,3 TRIFLUORO 2 HYDROXY 2 METHYLPROPIONAMIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; PROPIONAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; BLOOD PRESSURE REGULATION; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; ENANTIOMER; GUINEA PIG; HEART RATE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; URINE INCONTINENCE;

AMIDES; ANIMALS; CRICETINAE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; POTASSIUM CHANNELS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; URINARY BLADDER; URINARY INCONTINENCE;

EID: 10544224541     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960365n     Document Type: Article

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