-
1
-
-
0003736036
-
Global strategy for asthma management and prevention
-
Global Initiative for Asthma: Bethesda, MD: National Institute of Health; Publication No. 02-3659
-
Global Initiative for Asthma: Global strategy for asthma management and prevention, Bethesda, MD: National Institute of Health; Publication No. 02-3659 (2002).
-
(2002)
-
-
-
2
-
-
0003662479
-
Expert panel report 2: Guidelines for the diagnosis and management for asthma
-
National Asthma Education and Prevention Program: Bethesda, MD: National Institute of Health; Publication No. 55-4051
-
National Asthma Education and Prevention Program: Expert panel report 2: Guidelines for the diagnosis and management for asthma. Bethesda, MD: National Institute of Health; Publication No. 55-4051 (1997).
-
(1997)
-
-
-
3
-
-
3543035759
-
Worldwide variations in the prevalence of asthma symptoms: The international study of asthma and allergies In childhood (ISAAC)
-
Worldwide variations in the prevalence of asthma symptoms: the international study of asthma and allergies In childhood (ISAAC). Eur. Repir. J. 12(2), 315-335 (1998).
-
(1998)
Eur. Repir. J
, vol.12
, Issue.2
, pp. 315-335
-
-
-
4
-
-
0032562336
-
Surveillance for asthma: United States, 1960-1995
-
Mannino DM, Iloma DM, Pertowski CA et al.: Surveillance for asthma: United States, 1960-1995. Morb Mortal Wkly Rep 47, 1-27 (1998).
-
(1998)
Morb Mortal Wkly Rep
, vol.47
, pp. 1-27
-
-
Mannino, D.M.1
Iloma, D.M.2
Pertowski, C.A.3
-
5
-
-
2342590065
-
The global burden of asthma: Executive summary of the GINA Dissemination Committee Report
-
Masoli M, Fabian D, Holt S, Beasley R: The global burden of asthma: Executive summary of the GINA Dissemination Committee Report. Allergy 59(5), 469-478 (2004).
-
(2004)
Allergy
, vol.59
, Issue.5
, pp. 469-478
-
-
Masoli, M.1
Fabian, D.2
Holt, S.3
Beasley, R.4
-
7
-
-
0034017468
-
Pharmacogenetics of asthma
-
Hall IP: Pharmacogenetics of asthma. Eur: Respir. J. 15, 449-451 (2000).
-
(2000)
Eur: Respir. J
, vol.15
, pp. 449-451
-
-
Hall, I.P.1
-
8
-
-
0033804352
-
Genomic approaches to understanding asthma
-
Palmer LJ, Cookson WO: Genomic approaches to understanding asthma. Genome Res. 10, 1280-1287 (2000)
-
(2000)
Genome Res
, vol.10
, pp. 1280-1287
-
-
Palmer, L.J.1
Cookson, W.O.2
-
9
-
-
0033010990
-
Gene by environment interaction and asthma
-
Weiss ST: Gene by environment interaction and asthma. Clin. Exp. Allergy 29 (Suppl 2), 96-99 (1999).
-
(1999)
Clin. Exp. Allergy
, vol.29
, Issue.SUPPL. 2
, pp. 96-99
-
-
Weiss, S.T.1
-
10
-
-
22244487333
-
Asthma epidemiology
-
Annesi-Maesano I: Asthma epidemiology. Rev Prat. 55(12), 1295-1298 (2005)
-
(2005)
Rev Prat
, vol.55
, Issue.12
, pp. 1295-1298
-
-
Annesi-Maesano, I.1
-
12
-
-
0347925015
-
Personalised prescribing for asthma - Is pharmacogenetics the answer?
-
Dewar JC, Hall IP: Personalised prescribing for asthma - is pharmacogenetics the answer? J. Pharm. Pharmacol. 55(3), 279-289 (2003).
-
(2003)
J. Pharm. Pharmacol
, vol.55
, Issue.3
, pp. 279-289
-
-
Dewar, J.C.1
Hall, I.P.2
-
13
-
-
0035553086
-
Drug target pharmacogenomics: An overview
-
Johnson JA: Drug target pharmacogenomics: an overview. Am. J. Pharmacogenomics 1(4), 271-281 (2001).
-
(2001)
Am. J. Pharmacogenomics
, vol.1
, Issue.4
, pp. 271-281
-
-
Johnson, J.A.1
-
14
-
-
10744224159
-
A survey of genetic and epigenetic variation affecting human gene expression
-
Pastinen T, Sladek R, Gurd S et al.: A survey of genetic and epigenetic variation affecting human gene expression. Physiol. Genomics 16(2), 184-193 (2004).
-
(2004)
Physiol. Genomics
, vol.16
, Issue.2
, pp. 184-193
-
-
Pastinen, T.1
Sladek, R.2
Gurd, S.3
-
15
-
-
0025309090
-
2 receptor agonists in asthma: A comparison
-
2 receptor agonists in asthma: a comparison. J. Asthma 27(2), 101-109 (1990).
-
(1990)
J. Asthma
, vol.27
, Issue.2
, pp. 101-109
-
-
Lemanske Jr., R.F.1
Joad, J.2
-
16
-
-
0023762749
-
2-adrenoceptor agonist: Comparison with salbutamol in adult asthmatic patients
-
2-adrenoceptor agonist: comparison with salbutamol in adult asthmatic patients. Thorax 43(9), 674-678 (1988).
-
(1988)
Thorax
, vol.43
, Issue.9
, pp. 674-678
-
-
Ullman, A.1
Svedmyr, N.2
-
17
-
-
0033919439
-
Treatment of acute asthma: A new look at the old and at the new
-
Silverman R: Treatment of acute asthma: a new look at the old and at the new. Clin. Chest Med. 21, 361-379 (2000).
-
(2000)
Clin. Chest Med
, vol.21
, pp. 361-379
-
-
Silverman, R.1
-
21
-
-
0028068550
-
2-adrenergic receptor impart distinct agonist-promoted regulatory properties
-
2-adrenergic receptor impart distinct agonist-promoted regulatory properties. Biochemistry 33(32), 9414-9419 (1994).
-
(1994)
Biochemistry
, vol.33
, Issue.32
, pp. 9414-9419
-
-
Green, S.A.1
Turki, J.2
Innis, M.3
Liggett, S.B.4
-
24
-
-
0032589460
-
2-adrenergic receptor polymorphisms affect airway responsiveness to salbutamol in asthmatics
-
2-adrenergic receptor polymorphisms affect airway responsiveness to salbutamol in asthmatics. J. Asthma 36, 583-590 (1999).
-
(1999)
J. Asthma
, vol.36
, pp. 583-590
-
-
Kotani, Y.1
Nishimura, Y.2
Maeda, H.3
Yokoyama, M.4
-
25
-
-
0345501553
-
2-adrenergic receptor on albuterol bronchodilator pharmacodynamics
-
2-adrenergic receptor on albuterol bronchodilator pharmacodynamics. Clin. Pharmacol. Ther. 65(5), 519-525 (1999).
-
(1999)
Clin. Pharmacol. Ther
, vol.65
, Issue.5
, pp. 519-525
-
-
Lima, J.J.1
Thomason, D.B.2
Mohamed, M.H.3
Eberle, L.V.4
Self, T.H.5
Johnson, J.A.6
-
28
-
-
20144363204
-
Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma
-
Choudhry S, Ung N, Avila PC et al.: Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am. J. Respir. Crit. Care Med. 171(6), 563-570 (2005).
-
(2005)
Am. J. Respir. Crit. Care Med
, vol.171
, Issue.6
, pp. 563-570
-
-
Choudhry, S.1
Ung, N.2
Avila, P.C.3
-
29
-
-
21444441069
-
2-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics
-
2-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics. Pharmacogenomics. 6(4), 399-410 (2005).
-
(2005)
Pharmacogenomics
, vol.6
, Issue.4
, pp. 399-410
-
-
Kukreti, R.1
Bhatnagar, P.2
B-Rao, C.3
-
31
-
-
6944232728
-
Use of regularly scheduled albuterol treatment in asthma: Genotype-stratified, randomized, placebo-controlled cross-over trial
-
Israel E, Chinchilli VM, Ford JG et al.: Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomized, placebo-controlled cross-over trial. Lancet (364), 1505-1512 (2004).
-
(2004)
Lancet
, Issue.364
, pp. 1505-1512
-
-
Israel, E.1
Chinchilli, V.M.2
Ford, J.G.3
-
32
-
-
0029665825
-
2-adrenoceptor polymorphisms: Are they clinically important?
-
2-adrenoceptor polymorphisms: are they clinically important? Thorax 51 (4), 351-353 (1996).
-
(1996)
Thorax
, vol.51
, Issue.4
, pp. 351-353
-
-
Hall, I.P.1
-
33
-
-
0029045292
-
2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects
-
2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects. Lancet 345, 1213-1214 (1995).
-
(1995)
Lancet
, vol.345
, pp. 1213-1214
-
-
Hall, I.P.1
Wheatley, A.2
Wilding, P.3
Liggett, S.B.4
-
34
-
-
0027519404
-
2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor
-
2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor. J. Biol. Chem. 268(31), 23116-23121 (1993).
-
(1993)
J. Biol. Chem
, vol.268
, Issue.31
, pp. 23116-23121
-
-
Green, S.A.1
Cole, G.2
Jacinto, M.3
Innis, M.4
Liggett, S.B.5
-
35
-
-
0028145741
-
2 adrenergic receptor mRNA inhibits receptor synthesis
-
2 adrenergic receptor mRNA inhibits receptor synthesis. J. Biol. Chem. 269(6), 4497-4505 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, Issue.6
, pp. 4497-4505
-
-
Parola, A.L.1
Kobilka, B.K.2
-
36
-
-
0034930262
-
The relative power of SNPs and haplotype as genetic markers for association tests
-
Bader JS: The relative power of SNPs and haplotype as genetic markers for association tests. Pharmacogenomics 2(1), 11-24 (2001).
-
(2001)
Pharmacogenomics
, vol.2
, Issue.1
, pp. 11-24
-
-
Bader, J.S.1
-
37
-
-
0034641736
-
Complex promoter and coding region β-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness
-
Drysdale CM, McGraw DW, Stack CB et al.: Complex promoter and coding region β-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness. Proc. Natl Acad. Sci. USA 97(19), 10483-10488 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.19
, pp. 10483-10488
-
-
Drysdale, C.M.1
McGraw, D.W.2
Stack, C.B.3
-
38
-
-
0031034624
-
The British guidelines on asthma management: Review and position statement
-
British Thoracic Society
-
British Thoracic Society. The British guidelines on asthma management: review and position statement. Thorax 52 (Suppl. 1), 1-21 (1997).
-
(1997)
Thorax
, vol.52
, Issue.SUPPL. 1
, pp. 1-21
-
-
-
39
-
-
0024545638
-
Gene regulation by steroid hormones
-
Beato M: Gene regulation by steroid hormones. Cell 56, 335-344 (1989).
-
(1989)
Cell
, vol.56
, pp. 335-344
-
-
Beato, M.1
-
41
-
-
0030943735
-
Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance
-
Koper JW, Stolk RP, de Lange P et al.: Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance. Hum. Genet. 99(5), 663-668 (1997).
-
(1997)
Hum. Genet
, vol.99
, Issue.5
, pp. 663-668
-
-
Koper, J.W.1
Stolk, R.P.2
de Lange, P.3
-
42
-
-
0034845924
-
Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance
-
Ruiz M, Lind U, Gafvels M et al.: Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance. Clin. Endocrinol. 55(3), 363-371 (2001).
-
(2001)
Clin. Endocrinol
, vol.55
, Issue.3
, pp. 363-371
-
-
Ruiz, M.1
Lind, U.2
Gafvels, M.3
-
43
-
-
0026026319
-
Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance
-
Hurley DM, Accili D, Stratakis CA et al.: Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance. J. Clin. Invest. 87(2), 680-686 (1991).
-
(1991)
J. Clin. Invest
, vol.87
, Issue.2
, pp. 680-686
-
-
Hurley, D.M.1
Accili, D.2
Stratakis, C.A.3
-
44
-
-
0027217319
-
A mutation of the glucocorticoid receptor in primary cortisol resistance
-
Malchoff DM, Brufsky A, Reardon G et al.: A mutation of the glucocorticoid receptor in primary cortisol resistance. J. Clin. Invest. 91(5), 1918-1925 (1993).
-
(1993)
J. Clin. Invest
, vol.91
, Issue.5
, pp. 1918-1925
-
-
Malchoff, D.M.1
Brufsky, A.2
Reardon, G.3
-
45
-
-
15144360854
-
A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo
-
Huizenga NA, Koper JW, De Lange P et al.: A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo. J Clin. Endocrinol. Metab. 83(1), 144-151 (1998).
-
(1998)
J Clin. Endocrinol. Metab
, vol.83
, Issue.1
, pp. 144-151
-
-
Huizenga, N.A.1
Koper, J.W.2
De Lange, P.3
-
46
-
-
0027521592
-
Nuclear receptor/AP-1 interactions
-
Pfahl M: Nuclear receptor/AP-1 interactions. Endocrinol Rev. 14(5), 651-658 (1993).
-
(1993)
Endocrinol Rev
, vol.14
, Issue.5
, pp. 651-658
-
-
Pfahl, M.1
-
47
-
-
0028107237
-
Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor
-
Ray A, Prefontaine KE: Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl Acad. Sci. USA 91(2), 752-756 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, Issue.2
, pp. 752-756
-
-
Ray, A.1
Prefontaine, K.E.2
-
48
-
-
0031842804
-
Transcription factors and asthma
-
Barnes PJ, Adcock IM: Transcription factors and asthma. Eur. Respir. J. 12(1), 221-234 (1998).
-
(1998)
Eur. Respir. J
, vol.12
, Issue.1
, pp. 221-234
-
-
Barnes, P.J.1
Adcock, I.M.2
-
49
-
-
0029741438
-
Steroid resistance in asthma: Molecular mechanisms
-
Adcock IM: Steroid resistance in asthma: molecular mechanisms. Am. J. Respir. Crit. Care Med. 154, S58-S61 (1996).
-
(1996)
Am. J. Respir. Crit. Care Med
, vol.154
-
-
Adcock, I.M.1
-
50
-
-
0032535369
-
Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
-
Lane SJ, Adcock IM, Richards D, Hawrylowicz C, Barnes PJ, Lee TH: Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes. J. Clin. Invest. 102(12), 2156-2164 (1998).
-
(1998)
J. Clin. Invest
, vol.102
, Issue.12
, pp. 2156-2164
-
-
Lane, S.J.1
Adcock, I.M.2
Richards, D.3
Hawrylowicz, C.4
Barnes, P.J.5
Lee, T.H.6
-
51
-
-
17044446216
-
Novel single nucleotide polymorphisms (SNPs) at positions 497 (T/G) and 829 (T/C) in the human c-FOS gene and haplotype association
-
Umino Y, Hohjoh H, Tokunaga K: Novel single nucleotide polymorphisms (SNPs) at positions 497 (T/G) and 829 (T/C) in the human c-FOS gene and haplotype association. Hum. Mutat. 16(3), 279 (2000).
-
(2000)
Hum. Mutat
, vol.16
, Issue.3
, pp. 279
-
-
Umino, Y.1
Hohjoh, H.2
Tokunaga, K.3
-
52
-
-
26944442800
-
Asthma steroid pharmacogenetics: A study strategy to identify replicated treatment responses
-
Weiss ST, Lake SL, Silverman ES et al.: Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses. Proc. Am. Thorac. Soc. 1(4), 364-367 (2004).
-
(2004)
Proc. Am. Thorac. Soc
, vol.1
, Issue.4
, pp. 364-367
-
-
Weiss, S.T.1
Lake, S.L.2
Silverman, E.S.3
-
53
-
-
3242687981
-
Corticosteroid pharmacogenetics: Association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids
-
Tantisira KG, Lake S, Silverman ES et al.: Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum. Mol. Genet. 13(13), 1353-1359 (2004).
-
(2004)
Hum. Mol. Genet
, vol.13
, Issue.13
, pp. 1353-1359
-
-
Tantisira, K.G.1
Lake, S.2
Silverman, E.S.3
-
54
-
-
0033012176
-
The Childhood Asthma Management Program (CAMP): Design, rationale, and methods
-
The Childhood Asthma Management Program Group
-
The Childhood Asthma Management Program Group. The Childhood Asthma Management Program (CAMP): design, rationale, and methods. Control. Clin. Trials 20, 91-120 (1999).
-
(1999)
Control. Clin. Trials
, vol.20
, pp. 91-120
-
-
-
55
-
-
19944427616
-
TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids
-
Tantisira KG, Hwang ES, Raby BA et al.: TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc. Natl Acad. Sci. USA 101(52), 18099-18104 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.52
, pp. 18099-18104
-
-
Tantisira, K.G.1
Hwang, E.S.2
Raby, B.A.3
-
56
-
-
0027689913
-
New drugs for asthma
-
Barnes N: New drugs for asthma. Practitioner 237, 870-873 (1993).
-
(1993)
Practitioner
, vol.237
, pp. 870-873
-
-
Barnes, N.1
-
57
-
-
0029090308
-
Drugs affecting the leukotriene pathway in asthma
-
Barnes NC, Kuitert LM: Drugs affecting the leukotriene pathway in asthma. Br. J. Clin. Pract. 49, 262-266 (1995).
-
(1995)
Br. J. Clin. Pract
, vol.49
, pp. 262-266
-
-
Barnes, N.C.1
Kuitert, L.M.2
-
58
-
-
0030995299
-
Leukotriene receptor antagonists: Clinical effects
-
Barnes N: Leukotriene receptor antagonists: clinical effects. J. R. Soc. Med. 90, 200-204 (1997).
-
(1997)
J. R. Soc. Med.
, vol.90
, pp. 200-204
-
-
Barnes, N.1
-
59
-
-
0020597565
-
Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
-
Samuelsson B: Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220(4597), 568-575 (1983).
-
(1983)
Science
, vol.220
, Issue.4597
, pp. 568-575
-
-
Samuelsson, B.1
-
60
-
-
0020691486
-
Effects of leukotriene D on the airways in asthma
-
Griffin M, Weiss JW, Leitch AG et al.: Effects of leukotriene D on the airways in asthma. N. Engl. J. Med. 308(8), 436-439 (1983).
-
(1983)
N. Engl. J. Med
, vol.308
, Issue.8
, pp. 436-439
-
-
Griffin, M.1
Weiss, J.W.2
Leitch, A.G.3
-
61
-
-
0023152470
-
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects
-
Davidson AB, Lee TH, Scanlon PD et al.: Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. Am. Rev. Respir. Dis. 135(2), 333-337 (1987).
-
(1987)
Am. Rev. Respir. Dis
, vol.135
, Issue.2
, pp. 333-337
-
-
Davidson, A.B.1
Lee, T.H.2
Scanlon, P.D.3
-
62
-
-
0031037332
-
Pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors in the management of asthma
-
Drazen JM: Pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors in the management of asthma. Pharmacotherapy 17(1 Pt 2), 22S-30S (1997).
-
(1997)
Pharmacotherapy
, vol.17
, Issue.1 PART 2
-
-
Drazen, J.M.1
-
63
-
-
0023177955
-
Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects
-
Samuelsson B, Dahlen SE, Lindgren JA, Rouzer CA, Serhan CN: Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 237 (4819), 1171-1176 (1987).
-
(1987)
Science
, vol.237
, Issue.4819
, pp. 1171-1176
-
-
Samuelsson, B.1
Dahlen, S.E.2
Lindgren, J.A.3
Rouzer, C.A.4
Serhan, C.N.5
-
64
-
-
0031003816
-
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription
-
In KH, Asano K, Beier D et al.: Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J. Clin. Invest. 99(5), 1130-1137 (1997).
-
(1997)
J. Clin. Invest
, vol.99
, Issue.5
, pp. 1130-1137
-
-
In, K.H.1
Asano, K.2
Beier, D.3
-
65
-
-
0032132831
-
Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants
-
Silverman ES, Du J, De Sanctis GT et al.: Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. Am. J. Respir. Cell Mol. Biol. 19(2), 316-323 (1998).
-
(1998)
Am. J. Respir. Cell Mol. Biol
, vol.19
, Issue.2
, pp. 316-323
-
-
Silverman, E.S.1
Du, J.2
De Sanctis, G.T.3
-
66
-
-
0033059209
-
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
-
Drazen JM, Yandava CN, Dube L et al.: Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nature Genet. 22(2), 168-170 (1999).
-
(1999)
Nature Genet
, vol.22
, Issue.2
, pp. 168-170
-
-
Drazen, J.M.1
Yandava, C.N.2
Dube, L.3
-
67
-
-
0000451558
-
Effects of polymorphisms in the promoter region of 5-lipoxygenase and LTC4 synthase on the clinical response to zafirlukast and fluticasone
-
Anderson W, Kalberg C, Edward L et al.: Effects of polymorphisms in the promoter region of 5-lipoxygenase and LTC4 synthase on the clinical response to zafirlukast and fluticasone. Eur. Respir. J. 16(Suppl B), 183s (2000).
-
(2000)
Eur. Respir. J
, vol.16
, Issue.SUPPL. B
-
-
Anderson, W.1
Kalberg, C.2
Edward, L.3
-
68
-
-
0033600291
-
Characterization of the human cysteinyl leukotriene CysLTI receptor
-
Lynch KR, O'Neill GP, Liu Q et al.: Characterization of the human cysteinyl leukotriene CysLTI receptor. Nature 399(6738), 789-793 (1999).
-
(1999)
Nature
, vol.399
, Issue.6738
, pp. 789-793
-
-
Lynch, K.R.1
O'Neill, G.P.2
Liu, Q.3
-
69
-
-
0033803781
-
Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast
-
Sampson AP, Siddiqui S, Buchanan D et al.: Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 55(Suppl. 2), S28-S31 (2000).
-
(2000)
Thorax
, vol.55
, Issue.2 SUPPL.
-
-
Sampson, A.P.1
Siddiqui, S.2
Buchanan, D.3
-
70
-
-
0031590522
-
4 synthase promoter polymorphism and risk of aspirin-induced asthma
-
4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 350 (9091), 1599-1600 (1997).
-
(1997)
Lancet
, vol.350
, Issue.9091
, pp. 1599-1600
-
-
Sanak, M.1
Simon, H.U.2
Szczeklik, A.3
-
71
-
-
0033052113
-
Recent advances in our understanding of the use of theophylline in the treatment of asthma
-
Page CP: Recent advances in our understanding of the use of theophylline in the treatment of asthma. J. Clin. Pharmacol. 39(3), 237-240 (1999).
-
(1999)
J. Clin. Pharmacol
, vol.39
, Issue.3
, pp. 237-240
-
-
Page, C.P.1
-
72
-
-
0017752874
-
Relationship of theophylline clearance to oral dosage in children with chronic asthma
-
Ginchansky E, Weinberger M: Relationship of theophylline clearance to oral dosage in children with chronic asthma. J. Pediatr. 91(4), 655-660 (1977).
-
(1977)
J. Pediatr
, vol.91
, Issue.4
, pp. 655-660
-
-
Ginchansky, E.1
Weinberger, M.2
-
73
-
-
0017181445
-
Pharmacokinetics of theophylline in children with asthma
-
Ellis EF, Koysooko R, Levy G: Pharmacokinetics of theophylline in children with asthma. Pediatrics 58(4), 542-547(1976).
-
(1976)
Pediatrics
, vol.58
, Issue.4
, pp. 542-547
-
-
Ellis, E.F.1
Koysooko, R.2
Levy, G.3
-
74
-
-
0021844841
-
Polymorphism of theophylline metabolism in man
-
Miller CA, Slusher LB, Vesell ES: Polymorphism of theophylline metabolism in man. J. Clin. Invest. 75(5), 1415-1425 (1985).
-
(1985)
J. Clin. Invest
, vol.75
, Issue.5
, pp. 1415-1425
-
-
Miller, C.A.1
Slusher, L.B.2
Vesell, E.S.3
-
75
-
-
0024297084
-
Ipratropium bromide
-
Gross NJ: Ipratropium bromide. N. Engl. J. Med. 319, 486-494 (1988).
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 486-494
-
-
Gross, N.J.1
-
77
-
-
0025191514
-
Muscarinic M3 receptor mediates contraction of human central and peripheral airway smooth muscle
-
Roffel AF, Elzinga CRS, Zaagsma J: Muscarinic M3 receptor mediates contraction of human central and peripheral airway smooth muscle. Pulmon. Pharmacol. 3, 47-51 (1990).
-
(1990)
Pulmon. Pharmacol
, vol.3
, pp. 47-51
-
-
Roffel, A.F.1
Elzinga, C.R.S.2
Zaagsma, J.3
-
78
-
-
0025999794
-
Muscarinic receptor subtypes coupled to generation of different second messengers in isolated tracheal smooth muscle cells
-
Yang CM, Chou SP, Sung TC: Muscarinic receptor subtypes coupled to generation of different second messengers in isolated tracheal smooth muscle cells. Br. J. Pharmacol. 104(3), 613-618 (1991).
-
(1991)
Br. J. Pharmacol
, vol.104
, Issue.3
, pp. 613-618
-
-
Yang, C.M.1
Chou, S.P.2
Sung, T.C.3
-
79
-
-
0026612959
-
M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle
-
Fernandes LB, Fryer AD, Hirshman CA: M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle. J. Pharmacol. Exp. Ther. 262(1), 119-126 (1992).
-
(1992)
J. Pharmacol. Exp. Ther
, vol.262
, Issue.1
, pp. 119-126
-
-
Fernandes, L.B.1
Fryer, A.D.2
Hirshman, C.A.3
-
80
-
-
0034981868
-
Mutation screening of the muscarinic M(2) and M(3) receptor genes in normal and asthmatic subjects
-
Fenech AG, Ebejer MJ, Felice AE, Ellul-Micallef R, Hall IP: Mutation screening of the muscarinic M(2) and M(3) receptor genes in normal and asthmatic subjects. Br. J. Pharmacol. 133(1), 43-48 (2001).
-
(2001)
Br. J. Pharmacol
, vol.133
, Issue.1
, pp. 43-48
-
-
Fenech, A.G.1
Ebejer, M.J.2
Felice, A.E.3
Ellul-Micallef, R.4
Hall, I.P.5
-
81
-
-
0036661035
-
Mutation screening of the muscarinic M2 and M3 receptor genes in asthmatics, outgrow subjects, and normal controls
-
Yamamoto T, Yamashita N, Kuwabara M et al.: Mutation screening of the muscarinic M2 and M3 receptor genes in asthmatics, outgrow subjects, and normal controls. Ann. Genet. 45(3), 109-113 (2002).
-
(2002)
Ann. Genet.
, vol.45
, Issue.3
, pp. 109-113
-
-
Yamamoto, T.1
Yamashita, N.2
Kuwabara, M.3
-
82
-
-
2342569763
-
Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle
-
Fenech AG, Billington CK, Swan C et al.: Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 30(5), 678-686 (2004).
-
(2004)
Am. J. Respir. Cell Mol. Biol
, vol.30
, Issue.5
, pp. 678-686
-
-
Fenech, A.G.1
Billington, C.K.2
Swan, C.3
-
83
-
-
0032437084
-
Recent advances in understanding the molecular basis of polymorphisms in genes encoding cytochrome P450 enzymes
-
Daly AK, Fairbrother KS, Smart J: Recent advances in understanding the molecular basis of polymorphisms in genes encoding cytochrome P450 enzymes. Toxicol. Lett. 102-103, 143-147 (1998).
-
(1998)
Toxicol. Lett
, vol.102-103
, pp. 143-147
-
-
Daly, A.K.1
Fairbrother, K.S.2
Smart, J.3
-
84
-
-
0032793249
-
Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
-
Ingelman-Sundberg M, Oscarson M, McLellan RA: Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. Trends Pharmacol. Sci. 20(8), 342-349 (1999).
-
(1999)
Trends Pharmacol. Sci
, vol.20
, Issue.8
, pp. 342-349
-
-
Ingelman-Sundberg, M.1
Oscarson, M.2
McLellan, R.A.3
-
85
-
-
0030783057
-
4 receptor antagonist, in humans
-
4 receptor antagonist, in humans. Drug Metab. Dispos. 25(9), 1022-1031 (1997).
-
(1997)
Drug Metab. Dispos
, vol.25
, Issue.9
, pp. 1022-1031
-
-
Chiba, M.1
Xu, X.2
Nishime, J.A.3
Balani, S.K.4
Lin, J.H.5
-
86
-
-
0029960236
-
The aliphatic oxidation of salmeterol to α-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A
-
Manchee GR, Eddershaw PJ, Ranshaw LE et al.: The aliphatic oxidation of salmeterol to α-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A. Drug Metab. Dispos. 24(5), 555-559 (1996).
-
(1996)
Drug Metab. Dispos
, vol.24
, Issue.5
, pp. 555-559
-
-
Manchee, G.R.1
Eddershaw, P.J.2
Ranshaw, L.E.3
-
87
-
-
0028878830
-
Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver
-
Jonsson G, Astrom A, Andersson P: Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab. Dispos. 23(1), 137-142 (1995).
-
(1995)
Drug Metab. Dispos
, vol.23
, Issue.1
, pp. 137-142
-
-
Jonsson, G.1
Astrom, A.2
Andersson, P.3
-
88
-
-
0029018483
-
Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation
-
Zhang ZY, Kaminsky LS: Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation. Biochem. Pharmacol. 50(2), 205-211 (1995).
-
(1995)
Biochem. Pharmacol
, vol.50
, Issue.2
, pp. 205-211
-
-
Zhang, Z.Y.1
Kaminsky, L.S.2
-
89
-
-
0034041373
-
Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in the human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis
-
Ieiri I, Tainaka H, Morita T et al.: Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in the human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis. Ther. Drug Monit. 22(3), 237-244 (2000).
-
(2000)
Ther. Drug Monit
, vol.22
, Issue.3
, pp. 237-244
-
-
Ieiri, I.1
Tainaka, H.2
Morita, T.3
-
90
-
-
0033980363
-
Phenotypic polymorphism and gender-related differences of CYP1A2 activity in a Chinese population
-
Ou-Yang DS, Huang SL, Wang W et al.: Phenotypic polymorphism and gender-related differences of CYP1A2 activity in a Chinese population. Br. J. Clin. Pharmacol. 49(2), 145-151 (2000).
-
(2000)
Br. J. Clin. Pharmacol
, vol.49
, Issue.2
, pp. 145-151
-
-
Ou-Yang, D.S.1
Huang, S.L.2
Wang, W.3
-
91
-
-
0028336794
-
Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: Absence of mutation prescribing the phenotype in the CYP1A2 gene
-
Nakajima M, Yokoi T, Mizutani M, Shin S, Kadlubar FF, Kamataki T: Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene. Cancer Epidemiol. Biomarkers Prev. 3(5), 413-421 (1994).
-
(1994)
Cancer Epidemiol. Biomarkers Prev
, vol.3
, Issue.5
, pp. 413-421
-
-
Nakajima, M.1
Yokoi, T.2
Mizutani, M.3
Shin, S.4
Kadlubar, F.F.5
Kamataki, T.6
-
92
-
-
0032751791
-
Detection of three genetic polymorphisms in the 5′-flanking region and intron 1 of human CYP1A2 in the Japanese population
-
Chida M, Yokoi T, Fukui T, Kinoshita M, Yokota J, Kamataki T: Detection of three genetic polymorphisms in the 5′-flanking region and intron 1 of human CYP1A2 in the Japanese population. Jpn J. Cancer Res. 90(9), 899-902 (1999).
-
(1999)
Jpn J. Cancer Res
, vol.90
, Issue.9
, pp. 899-902
-
-
Chida, M.1
Yokoi, T.2
Fukui, T.3
Kinoshita, M.4
Yokota, J.5
Kamataki, T.6
-
93
-
-
0032810704
-
Detailed modelling of caffeine metabolism and examination of the CYP1A2 gene: Lack of a polymorphism in CYP1A2 in Caucasians
-
Welfare MR, Aitkin M, Bassendine MF, Daly AK: Detailed modelling of caffeine metabolism and examination of the CYP1A2 gene: lack of a polymorphism in CYP1A2 in Caucasians. Pharmacogenetics 9(3), 367-375 (1999).
-
(1999)
Pharmacogenetics
, vol.9
, Issue.3
, pp. 367-375
-
-
Welfare, M.R.1
Aitkin, M.2
Bassendine, M.F.3
Daly, A.K.4
-
94
-
-
0032908778
-
Functional significance of a C → A polymorphism in intron 1 of the Cytochrome P450 CYP1A2 gene tested with caffeine
-
Sachse C, Brockmoller J, Bauer S, Roots I: Functional significance of a C → A polymorphism in intron 1 of the Cytochrome P450 CYP1A2 gene tested with caffeine. Br. J. Clin. Pharmacol. 47(4), 445-449 (1999).
-
(1999)
Br. J. Clin. Pharmacol
, vol.47
, Issue.4
, pp. 445-449
-
-
Sachse, C.1
Brockmoller, J.2
Bauer, S.3
Roots, I.4
-
95
-
-
0032929010
-
Genetic polymorphism in the 5′-flanking region of human CYP1A2 gene: Effect on the CYP1A2 inducibility in humans
-
Nakajima M, Yokoi T, Mizutani M, Kinoshita M, Funayama M, Kamataki T: Genetic polymorphism in the 5′-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans. J. Biochem. (Tokyo) 125(4), 803-808 (1999).
-
(1999)
J. Biochem. (Tokyo)
, vol.125
, Issue.4
, pp. 803-808
-
-
Nakajima, M.1
Yokoi, T.2
Mizutani, M.3
Kinoshita, M.4
Funayama, M.5
Kamataki, T.6
-
96
-
-
0010413096
-
Statistical Approaches in Psychopharmacogenetics
-
Lerer B (Ed.), Cambridge University Press, Cambridge, UK
-
Macciardi F: Statistical Approaches in Psychopharmacogenetics. In: Pharmacogenetics of Psychotropic Drugs. Lerer B (Ed.), Cambridge University Press, Cambridge, UK, 72-91 (2002).
-
(2002)
Pharmacogenetics of Psychotropic Drugs
, pp. 72-91
-
-
Macciardi, F.1
-
97
-
-
0037442092
-
Population stratification and spurious allelic association
-
Cardon LR, Palmer LJ: Population stratification and spurious allelic association. Lancet 361(9357), 598-604 (2003).
-
(2003)
Lancet
, vol.361
, Issue.9357
, pp. 598-604
-
-
Cardon, L.R.1
Palmer, L.J.2
-
98
-
-
0036907442
-
2-adrenergic receptor signaling pathways
-
2-adrenergic receptor signaling pathways. J. Allergy Clin. Immunol. 110(6 Suppl), S229-S235 (2002).
-
(2002)
J. Allergy Clin. Immunol
, vol.110
, Issue.6 SUPPL.
-
-
Benovic, J.L.1
-
99
-
-
0030860288
-
2 adrenoceptor polymorphism and susceptibility to bronchodilator desensitization in moderately severe stable asthmatics
-
2 adrenoceptor polymorphism and susceptibility to bronchodilator desensitization in moderately severe stable asthmatics. Lancet 350(9083), 995-999 (1997).
-
(1997)
Lancet
, vol.350
, Issue.9083
, pp. 995-999
-
-
Tan, S.1
Hall, I.P.2
Dewar, J.3
Dow, E.4
Lipworth, B.5
-
101
-
-
0035052741
-
2-adrenergic receptor on response to regular use of albuterol in asthma
-
2-adrenergic receptor on response to regular use of albuterol in asthma. Int. Arch. Allergy Immunol. 124(1-3), 183-186 (2001).
-
(2001)
Int. Arch. Allergy Immunol
, vol.124
, Issue.1-3
, pp. 183-186
-
-
Israel, E.1
Drazen, J.M.2
Liggett, S.B.3
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