Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription

Journal of Clinical Investigation

Volumn 99, Issue 5, 1997, Pages 1130-1137

  In, K H ^a,b   Asano, K ^a,b   Beier, D ^a,b   Grobholz, J ^a,b   Finn, P W ^a,b   Silverman, E K ^a,b   Silverman, E S ^a,b   Collins, T ^a,b   Fischer, A R ^a,b   Keith, T P ^c   Serino, K ^c   Kim, S W ^a,b   De Sanctis, G T ^a,b   Yandava, C ^a,b   Pillari, A ^a,b   Rubin, P ^d   Kemp, J ^d   Israel, E ^a,b   Busse, W ^d   Ledford, D ^d   Murray, J J ^e   Segal, A ^d   Tinkleman, D ^d   Drazen, J M ^a,b   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GENOME THERAPEUTICS CORPORATION   (United States)

^d ABBOTT LABORATORIES   (United States)

^e NONE

Author keywords

asthma; leukotrienes

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; ZINC FINGER PROTEIN;

ARTICLE; ASTHMA; BINDING SITE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; ELECTROPHORETIC MOBILITY; ENDOTHELIUM CELL; GENE ACTIVITY; GENE DELETION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; UMBILICAL VEIN;

EID: 0031003816     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119241     Document Type: Article

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