Effect of polymorphism of the β2-adrenergic receptor on response to regular use of albuterol in asthma

International Archives of Allergy and Immunology

Volumn 124, Issue 1-3, 2001, Pages 183-186

  Israel, Elliot ^a   Drazen, Jeffrey M ^a   Liggett, Stephen B ^h   Boushey, Homer A ^b   Cherniack, Reuben M ⁱ   Chinchilli, Vernon M ^f   Cooper, David M ^c   Fahy, John V ^b   Fish, James E ^j   Ford, Jean G ^d   Kraft, Monica ⁱ   Kunselman, Susan ^f   Lazarus, Stephen C ^b   Lemanske Jr , Robert F ^g   Martin, Richard J ⁱ   McLean, Diane E ^e   Peters, Stephen P ^j   Silverman, Edwin K ^k   Sorkness, Christine A ^g   Szefler, Stanley J ⁱ   Weiss, Scott T ^k   Yandava, Chandri N ^k   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARLEM HOSPITAL CENTER   (United States)

^e MONTEFIORE MEDICAL CENTER   (United States)

^f PENN STATE COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF WISCONSIN MADISON   (United States)

^h UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

ⁱ NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^j THOMAS JEFFERSON UNIVERSITY   (United States)

^k HARVARD MEDICAL SCHOOL   (United States)

more..

Author keywords

2 Adrenergic agonists; 2 Adrenergic receptor; Albuterol; Asthma

Indexed keywords

ANTIASTHMATIC AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; PLACEBO; SALBUTAMOL;

ADOLESCENT; ADRENERGIC SYSTEM; ADULT; ASTHMA; CHILD; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADOLESCENT; ADRENERGIC BETA-AGONISTS; ADULT; ALBUTEROL; ASTHMA; CHILD; COHORT STUDIES; FEMALE; GENOTYPE; HUMANS; MALE; PEAK EXPIRATORY FLOW RATE; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, BETA-2; TIME FACTORS;

EID: 0035052741     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053705     Document Type: Conference Paper

References (7)

1. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma
2. Mutations in the gene encoding for the beta2-adrenergic receptor in normal and asthmatic subjects
3. A polymorphism of the human beta 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor
4. Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impact distinct agonist-promoted regulatory properties
5. Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice
6. Influence of beta(2)-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells
7. Polymorphisms of the beta-2-adrenergic receptor and asthma