-
1
-
-
0011364893
-
Human erythropoietin gene: High level expression in stably transfected mammalian cells and chromosome localization
-
Powell JS, Berkner KL, Lebo RV, Adamson JW. Human erythropoietin gene: high level expression in stably transfected mammalian cells and chromosome localization. Proc Natl Acad Sci USA 1986; 83:6465-6469.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6465-6469
-
-
Powell, J.S.1
Berkner, K.L.2
Lebo, R.V.3
Adamson, J.W.4
-
2
-
-
0022523445
-
Regional assignment of the erythropoietin gene to human chromosome region 7pter-q22
-
Watkins PC, Eddy R, Hoffman N, Stanislovitis P, Beck AK, Galli J, Vellucci V, Gusella JF, Shows TB. Regional assignment of the erythropoietin gene to human chromosome region 7pter-q22. Cytogenet Cell Genet 1986; 42:214-218.
-
(1986)
Cytogenet Cell Genet
, vol.42
, pp. 214-218
-
-
Watkins, P.C.1
Eddy, R.2
Hoffman, N.3
Stanislovitis, P.4
Beck, A.K.5
Galli, J.6
Vellucci, V.7
Gusella, J.F.8
Shows, T.B.9
-
3
-
-
0022473616
-
Chromosomal assignment of the human erythropoietin gene and its DNA polymorphism
-
Law ML, Cai GY, Lin FK, Wei Q, Huang SZ, Hartz JH, Morse H, Lin CH, Jones C, Kao FT. Chromosomal assignment of the human erythropoietin gene and its DNA polymorphism. Proc Natl Acad Sci USA 1986; 83:6920-6924.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6920-6924
-
-
Law, M.L.1
Cai, G.Y.2
Lin, F.K.3
Wei, Q.4
Huang, S.Z.5
Hartz, J.H.6
Morse, H.7
Lin, C.H.8
Jones, C.9
Kao, F.T.10
-
4
-
-
0023550727
-
Structural characterization of natural human urinary and recombinant DNA-derived erythropoietin. Identification of des-arginine 166 erythro poietin
-
Recny MA, Scoble HA, Kim Y. Structural characterization of natural human urinary and recombinant DNA-derived erythropoietin. Identification of des-arginine 166 erythro poietin. J Biol Chem 1987; 262:17156-17163.
-
(1987)
J Biol Chem
, vol.262
, pp. 17156-17163
-
-
Recny, M.A.1
Scoble, H.A.2
Kim, Y.3
-
5
-
-
0021908684
-
The role of carbohydrate in erythropoietin action
-
Dordal MS, Wang FF, Goldwasser E. The role of carbohydrate in erythropoietin action. Endocrinology 1985; 116:2293-2299.
-
(1985)
Endocrinology
, vol.116
, pp. 2293-2299
-
-
Dordal, M.S.1
Wang, F.F.2
Goldwasser, E.3
-
6
-
-
0032188942
-
Efficiency of signalling through cytokine receptors depends critically on receptor orientation
-
Syed RS, Reid SW, Li C, Cheetham JC, Aoki KH, Liu B, Zhan H, Osslund TD, Chirino AJ, Zhang J, Finer-Moore J, Elliott S, Sitney K, Katz BA, Matthews DJ, Wendoloski JJ, Egrie J, Stroud RM. Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature 1998; 395:511-516.
-
(1998)
Nature
, vol.395
, pp. 511-516
-
-
Syed, R.S.1
Reid, S.W.2
Li, C.3
Cheetham, J.C.4
Aoki, K.H.5
Liu, B.6
Zhan, H.7
Osslund, T.D.8
Chirino, A.J.9
Zhang, J.10
Finer-Moore, J.11
Elliott, S.12
Sitney, K.13
Katz, B.A.14
Matthews, D.J.15
Wendoloski, J.J.16
Egrie, J.17
Stroud, R.M.18
-
7
-
-
0031671622
-
NMR structure of human erythropoietin and a comparison with its receptor bound conformation
-
Cheetham JC, Smith DM, Aoki KH, Stevenson JL, Hoeffel TJ, Syed RS, Egrie J, Harvey TS. NMR structure of human erythropoietin and a comparison with its receptor bound conformation. Nat Struct Biol 1998; 5:861-866.
-
(1998)
Nat Struct Biol
, vol.5
, pp. 861-866
-
-
Cheetham, J.C.1
Smith, D.M.2
Aoki, K.H.3
Stevenson, J.L.4
Hoeffel, T.J.5
Syed, R.S.6
Egrie, J.7
Harvey, T.S.8
-
8
-
-
0029763919
-
Lectin-binding assays for the isoforms of human erythropoietin:Comparison of urinary and four recombinant erythropoietins
-
Storring PL, Tiplady RJ, Gaines-Das RE, Rafferty B, Mistry YG. Lectin-binding assays for the isoforms of human erythropoietin:comparison of urinary and four recombinant erythropoietins. J Endocrinol 1996; 150:401-412.
-
(1996)
J Endocrinol
, vol.150
, pp. 401-412
-
-
Storring, P.L.1
Tiplady, R.J.2
Gaines-Das, R.E.3
Rafferty, B.4
Mistry, Y.G.5
-
9
-
-
0015353290
-
Electrophoretic behavior of erythropoietin in polyacrylamide gel
-
Dorado M, Langton AA, Brandan NC, Espada J. Electrophoretic behavior of erythropoietin in polyacrylamide gel. Biochem Med 1972; 6:238-245.
-
(1972)
Biochem Med
, vol.6
, pp. 238-245
-
-
Dorado, M.1
Langton, A.A.2
Brandan, N.C.3
Espada, J.4
-
10
-
-
0025948397
-
Comparisons of human, rat and mouse erythropoietins by isoelectric focusing: Differences between serum and urinary erythropoietins
-
Tam RC, Coleman SL, Tiplady RJ, Storring PL, Cotes PM. Comparisons of human, rat and mouse erythropoietins by isoelectric focusing: differences between serum and urinary erythropoietins. Br J Haematol 1991; 79:504-511.
-
(1991)
Br J Haematol
, vol.79
, pp. 504-511
-
-
Tam, R.C.1
Coleman, S.L.2
Tiplady, R.J.3
Storring, P.L.4
Cotes, P.M.5
-
11
-
-
0025123840
-
Molecular charge heterogeneity of human serum erythropoietin
-
Wide L, Bengtsson C. Molecular charge heterogeneity of human serum erythropoietin. Br J Haematol 1990; 76:121-127.
-
(1990)
Br J Haematol
, vol.76
, pp. 121-127
-
-
Wide, L.1
Bengtsson, C.2
-
12
-
-
0000119357
-
Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cells
-
Takeuchi M, Inoue N, Strickland TW, Kubota M, Wada M, Shimizu R, Hoshi S, Kozutsumi H, Takasaki S, Kobata A. Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cells. Proc Natl Acad Sci USA 1989; 86:7819-7822.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7819-7822
-
-
Takeuchi, M.1
Inoue, N.2
Strickland, T.W.3
Kubota, M.4
Wada, M.5
Shimizu, R.6
Hoshi, S.7
Kozutsumi, H.8
Takasaki, S.9
Kobata, A.10
-
13
-
-
0000212930
-
The role of carbohydrate on the biological activity of erythropoietin
-
[Abstr]
-
Egrie JC, Grant JR, Gillies D, Aoki KH, Strickland TW. The role of carbohydrate on the biological activity of erythropoietin. Glycoconjugate J 1993; 10:263 [Abstr].
-
(1993)
Glycoconjugate J
, vol.10
, pp. 263
-
-
Egrie, J.C.1
Grant, J.R.2
Gillies, D.3
Aoki, K.H.4
Strickland, T.W.5
-
14
-
-
0036865723
-
The enigma of the metabolic fate of circulating erythropoietin (Epo) in view of the pharmacokinetics of the recombinant drugs rhEpo and NESP
-
Jelkmann W. The enigma of the metabolic fate of circulating erythropoietin (Epo) in view of the pharmacokinetics of the recombinant drugs rhEpo and NESP. Eur J Haematol 2002; 69:265-274.
-
(2002)
Eur J Haematol
, vol.69
, pp. 265-274
-
-
Jelkmann, W.1
-
15
-
-
0242611254
-
Cloning and expression of the human erythropoietin gene
-
Lin FK, Suggs S, Lin CH, Browne JK, Smalling R, Egrie JC, Chen KK, Fox GM, Martin F, Stabinsky Z, Badrawi SM, Lai PH, Goldwasser E. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci USA 1985; 82:7580-7584.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 7580-7584
-
-
Lin, F.K.1
Suggs, S.2
Lin, C.H.3
Browne, J.K.4
Smalling, R.5
Egrie, J.C.6
Chen, K.K.7
Fox, G.M.8
Martin, F.9
Stabinsky, Z.10
Badrawi, S.M.11
Lai, P.H.12
Goldwasser, E.13
-
16
-
-
0023248840
-
Characterization of recombinant human erythropoietin produced in Chinese hamster ovary cells
-
Davis JM, Arakawa T, Strickland TW, Yphantis DA. Characterization of recombinant human erythropoietin produced in Chinese hamster ovary cells. Biochemistry 1987; 26:2633-2638.
-
(1987)
Biochemistry
, vol.26
, pp. 2633-2638
-
-
Davis, J.M.1
Arakawa, T.2
Strickland, T.W.3
Yphantis, D.A.4
-
17
-
-
0029348847
-
Effect of low dose recombinant human omega erythropoietin (rHuEPO) on anaemia in patients on hemodialysis
-
Acharya VN, Sinha DK, Almeida AF, Pathare AV. Effect of low dose recombinant human omega erythropoietin (rHuEPO) on anaemia in patients on hemodialysis. J Assoc Physicians India 1995; 43:539-542.
-
(1995)
J Assoc Physicians India
, vol.43
, pp. 539-542
-
-
Acharya, V.N.1
Sinha, D.K.2
Almeida, A.F.3
Pathare, A.V.4
-
18
-
-
0036125372
-
A comparison between epoetin omega and epoetin alfa in the correction of anemia in hemodialysis patients: A prospective, controlled crossover study
-
Bren A, Kandus A, Varl J, Buturovic J, Ponikvar R, Kveder R, Primozic S, Ivanovich P. A comparison between epoetin omega and epoetin alfa in the correction of anemia in hemodialysis patients: a prospective, controlled crossover study. Artif Organs 2002; 26:91-97.
-
(2002)
Artif Organs
, vol.26
, pp. 91-97
-
-
Bren, A.1
Kandus, A.2
Varl, J.3
Buturovic, J.4
Ponikvar, R.5
Kveder, R.6
Primozic, S.7
Ivanovich, P.8
-
19
-
-
0036197002
-
Epoetin omega for treatment of anemia in maintenance hemodialysis patients
-
Sikole A, Spasovski G, Zafirov D, Polenakovic M. Epoetin omega for treatment of anemia in maintenance hemodialysis patients. Clin Nephrol 2002; 57:237-245.
-
(2002)
Clin Nephrol
, vol.57
, pp. 237-245
-
-
Sikole, A.1
Spasovski, G.2
Zafirov, D.3
Polenakovic, M.4
-
20
-
-
0023645520
-
Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA
-
Sasaki H, Bothner B, Dell A, Fukuda M. Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA. J Biol Chem 1987; 262:12059-12076.
-
(1987)
J Biol Chem
, vol.262
, pp. 12059-12076
-
-
Sasaki, H.1
Bothner, B.2
Dell, A.3
Fukuda, M.4
-
21
-
-
0025268959
-
Physicochemical and biological comparison of recombinant human erythropoietin with human urinary erythropoietin
-
Imai N, Kawamura A, Higuchi M, Oh-eda M, Orita T, Kawaguchi T, Ochi N. Physicochemical and biological comparison of recombinant human erythropoietin with human urinary erythropoietin. J Biochem (Tokyo) 1990; 107:352-359.
-
(1990)
J Biochem (Tokyo)
, vol.107
, pp. 352-359
-
-
Imai, N.1
Kawamura, A.2
Higuchi, M.3
Oheda, M.4
Orita, T.5
Kawaguchi, T.6
Ochi, N.7
-
22
-
-
0035895071
-
Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin
-
Skibeli V, Nissen-Lie G, Torjesen P. Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin. Blood 2001; 98:3626-3634.
-
(2001)
Blood
, vol.98
, pp. 3626-3634
-
-
Skibeli, V.1
Nissen-Lie, G.2
Torjesen, P.3
-
23
-
-
0034997401
-
Development and characterization of novel erythropoiesis stimulating protein (NESP)
-
Egrie JK, Browne JK. Development and characterization of novel erythropoiesis stimulating protein (NESP). Br J Cancer 2001; 84:3-10.
-
(2001)
Br J Cancer
, vol.84
, pp. 3-10
-
-
Egrie, J.K.1
Browne, J.K.2
-
24
-
-
0032211174
-
Erythropoietin mRNA expression in human fetal and neonatal tissue
-
Dame C, Fahnenstich H, Freitag P, Hofmann D, Abdul NT, Bartmann P, Fandrey J. Erythropoietin mRNA expression in human fetal and neonatal tissue. Blood 1998; 92:3218-3225.
-
(1998)
Blood
, vol.92
, pp. 3218-3225
-
-
Dame, C.1
Fahnenstich, H.2
Freitag, P.3
Hofmann, D.4
Abdul, N.T.5
Bartmann, P.6
Fandrey, J.7
-
25
-
-
0027410945
-
Co-localization of erythropoietin mRNA and ecto-50-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin
-
Bachmann S, Le Hir M, Eckardt KU. Co-localization of erythropoietin mRNA and ecto-50-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem 1993; 41:335-341.
-
(1993)
J Histochem Cytochem
, vol.41
, pp. 335-341
-
-
Bachmann, S.1
Le Hir, M.2
Eckardt, K.U.3
-
26
-
-
0027367661
-
Identification of the renal erythropoietin-producing cells using transgenic mice
-
Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ, Johnson MH, Ratcliffe PJ. Identification of the renal erythropoietin-producing cells using transgenic mice. Kidney Int 1993; 44:1149-1162.
-
(1993)
Kidney Int
, vol.44
, pp. 1149-1162
-
-
Maxwell, P.H.1
Osmond, M.K.2
Pugh, C.W.3
Heryet, A.4
Nicholls, L.G.5
Tan, C.C.6
Doe, B.G.7
Ferguson, D.J.8
Johnson, M.H.9
Ratcliffe, P.J.10
-
27
-
-
0031019656
-
Sites of erythropoietin production
-
Maxwell PH, Ferguson DJ, Nicholls LG, Iredale JP, Pugh CW, Johnson MH, Ratcliffe PJ. Sites of erythropoietin production. Kidney Int 1997; 51:393-401.
-
(1997)
Kidney Int
, vol.51
, pp. 393-401
-
-
Maxwell, P.H.1
Ferguson, D.J.2
Nicholls, L.G.3
Iredale, J.P.4
Pugh, C.W.5
Johnson, M.H.6
Ratcliffe, P.J.7
-
28
-
-
0029976021
-
Erythropoietin gene expression in human, monkey and murine brain
-
Marti HH, Wenger RH, Rivas LA, Straumann U, Digicaylioglu M, Henn V, Yonekawa Y, Bauer C, Gassmann M. Erythropoietin gene expression in human, monkey and murine brain. Eur J Neurosci 1996; 8:666-676.
-
(1996)
Eur J Neurosci
, vol.8
, pp. 666-676
-
-
Marti, H.H.1
Wenger, R.H.2
Rivas, L.A.3
Straumann, U.4
Digicaylioglu, M.5
Henn, V.6
Yonekawa, Y.7
Bauer, C.8
Gassmann, M.9
-
29
-
-
0036705708
-
Erythropoietin therapy for acute stroke is both safe and beneficial
-
Ehrenreich H, Hasselblatt M, Dembrowski C, Cepek L, Lewczuk P, Stiefel M, Rustenbeck H-H, Breiter N, Jacob S, Knerlich F, Bohn M, Poser W, Rüther E, Kochen M, Gefeller O, Gleiter C, Wessel TC, De Ryck M, Itri L, Prange H, Cerami A, Brines M, Sirén A-L. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med 2002; 8:495-505.
-
(2002)
Mol Med
, vol.8
, pp. 495-505
-
-
Ehrenreich, H.1
Hasselblatt, M.2
Dembrowski, C.3
Cepek, L.4
Lewczuk, P.5
Stiefel, M.6
Rustenbeck, H.-H.7
Breiter, N.8
Jacob, S.9
Knerlich, F.10
Bohn, M.11
Poser, W.12
Rüther, E.13
Kochen, M.14
Gefeller, O.15
Gleiter, C.16
Wessel, T.C.17
De Ryck, M.18
Itri, L.19
Prange, H.20
Cerami, A.21
Brines, M.22
Sirén, A.-L.23
more..
-
30
-
-
0026526168
-
Erythropoietin: Structure, control of production, and function
-
Jelkmann W. Erythropoietin: structure, control of production, and function. Physiol Rev 1992; 72:449-489.
-
(1992)
Physiol Rev
, vol.72
, pp. 449-489
-
-
Jelkmann, W.1
-
31
-
-
0036037635
-
From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway
-
Ratcliffe P. From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway. Blood Purif 2002; 20:445-450.
-
(2002)
Blood Purif
, vol.20
, pp. 445-450
-
-
Ratcliffe, P.1
-
32
-
-
0036320934
-
Cellular adaptation to hypoxia:O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
-
Wenger RH. Cellular adaptation to hypoxia:O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J 2002; 16:1151-1162.
-
(2002)
FASEB J
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
33
-
-
0027210562
-
General involvement of hypoxiainducible factor 1 in transcriptional response to hypoxia
-
Wang GL, Semenza GL. General involvement of hypoxiainducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 1993; 90:4304-4308.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
34
-
-
0029051439
-
Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92:5510-5514.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
35
-
-
0029859510
-
Hypoxia -inducible factor 1 levels vary exponentially over a physio logically relevant range of O2 tension
-
Jiang BH, Semenza GL, Bauer C, Marti HH. Hypoxia -inducible factor 1 levels vary exponentially over a physio logically relevant range of O2 tension. Am J Physiol 1996; 271:C1172-C1180.
-
(1996)
Am J Physiol
, vol.271
, pp. C1172-C1180
-
-
Jiang, B.H.1
Semenza, G.L.2
Bauer, C.3
Marti, H.H.4
-
36
-
-
0035903468
-
Independent function of two destruction domains in hypoxiainducible factor-a chains activated by prolyl hydroxylation
-
Masson N, William C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxiainducible factor-a chains activated by prolyl hydroxylation. EMBO J 2001; 20:5197-5206.
-
(2001)
EMBO J
, vol.20
, pp. 5197-5206
-
-
Masson, N.1
William, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
37
-
-
0035917808
-
Targeting of HIF-a to the Von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ. Targeting of HIF-a to the Von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
38
-
-
0035917313
-
HIFa targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
-
Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG Jr. HIFa targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001; 292:464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin, W.G.10
-
39
-
-
17944375360
-
C
-
Epstein ACR, Gleadle JM, McNeill LA, Hewitson KS, O’Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation Cell. 2001; 107:43-54.
-
(2001)
Elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation Cell.
, vol.107
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O’Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
40
-
-
0035834409
-
A conserved family of prolyl-4- hydroxylases that modify HIF
-
Bruick RK, McKnight SL. A conserved family of prolyl-4- hydroxylases that modify HIF. Science 2001; 294:1337-1340.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
41
-
-
0035887011
-
FIH-1: A novel protein that interacts with HIF-1a and VHL to mediate repression of HIF-1 transcriptional activity
-
Mahon PC, Hirota K, Semenza GL. FIH-1: a novel protein that interacts with HIF-1a and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 2001; 15:2675-2686.
-
(2001)
Genes Dev
, vol.15
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
42
-
-
18544386401
-
Hypoxia inducible factor (HIF) asparagine hydroxylase is identical to Factor Inhibiting HIF (FIH) and is related to the cupin structural family
-
Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ. Hypoxia inducible factor (HIF) asparagine hydroxylase is identical to Factor Inhibiting HIF (FIH) and is related to the cupin structural family. J Biol Chem 2002; 277:26351-26355.
-
(2002)
J Biol Chem
, vol.277
, pp. 26351-26355
-
-
Hewitson, K.S.1
McNeill, L.A.2
Riordan, M.V.3
Tian, Y.M.4
Bullock, A.N.5
Welford, R.W.6
Elkins, J.M.7
Oldham, N.J.8
Bhattacharya, S.9
Gleadle, J.M.10
Ratcliffe, P.J.11
Pugh, C.W.12
Schofield, C.J.13
-
43
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002; 16:1466-1471.
-
(2002)
Genes Dev
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
Peet, D.J.2
Gorman, J.J.3
Whelan, D.A.4
Whitelaw, M.L.5
Bruick, R.K.6
-
44
-
-
0036846033
-
Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803
-
McNeill LA, Hewitson KS, Claridge TD, Seibel JF, Horsfall LE. Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803. Biochem J 2003; 367:571-575.
-
(2003)
Biochem J
, vol.367
, pp. 571-575
-
-
McNeill, L.A.1
Hewitson, K.S.2
Claridge, T.D.3
Seibel, J.F.4
Horsfall, L.E.5
-
45
-
-
0037386143
-
Intracellular localisation of human HIF-1alpha hydroxylases:Implications for oxygen sensing
-
Metzen E, Berchner-Pfannschmidt U, Stengel P, Marxsen JH, Stolze I, Klinger M, Huang WQ, Wotzlaw C, Hellwig-Buergel T, Jelkmann W, Acker H, Fandrey J. Intracellular localisation of human HIF-1alpha hydroxylases:implications for oxygen sensing. J Cell Science 2003; 116:1319-1326.
-
(2003)
J Cell Science
, vol.116
, pp. 1319-1326
-
-
Metzen, E.1
Berchner-Pfannschmidt, U.2
Stengel, P.3
Marxsen, J.H.4
Stolze, I.5
Klinger, M.6
Huang, W.Q.7
Wotzlaw, C.8
Hellwig-Buergel, T.9
Jelkmann, W.10
Acker, H.11
Fandrey, J.12
-
46
-
-
0036391915
-
Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors
-
Oehme F, Ellinghaus P, Kolkhof P, Smith TJ, Ramakrishnan S, Hütter J, Schramm M, Flamme I. Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors. Biochem Biophys Res Commun 2002; 296:343-349.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 343-349
-
-
Oehme, F.1
Ellinghaus, P.2
Kolkhof, P.3
Smith, T.J.4
Ramakrishnan, S.5
Hütter, J.6
Schramm, M.7
Flamme, I.8
-
47
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxiainducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxiainducible factors for oxygen-dependent proteolysis. Nature 1999; 399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
48
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the bdomain of the von Hippel-Lindau protein
-
Ohh M, Park CW, Ivan M, Hoffman MA, Kim TY, Huang LE, Pavletich N, Chau V, Kaelin WG. Ubiquitination of hypoxia-inducible factor requires direct binding to the bdomain of the von Hippel-Lindau protein. Nat Cell Biol 2000; 2:423-427.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
Hoffman, M.A.4
Kim, T.Y.5
Huang, L.E.6
Pavletich, N.7
Chau, V.8
Kaelin, W.G.9
-
49
-
-
0030961006
-
Hypoxia-inducible factor 1a (HIF-1a) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
-
Salceda S, Caro J. Hypoxia-inducible factor 1a (HIF-1a) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 1997; 272:22642-22647.
-
(1997)
J Biol Chem
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
50
-
-
0035478294
-
Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation
-
Minet E, Michel G, Mottet D, Raes M, Michiels C. Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation. Free Radic Biol Med 2001; 31:847-855.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 847-855
-
-
Minet, E.1
Michel, G.2
Mottet, D.3
Raes, M.4
Michiels, C.5
-
51
-
-
0035880239
-
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
-
Vaux EC, Metzen E, Yeates KM, Ratcliffe PJ. Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 2001; 98:296-302.
-
(2001)
Blood
, vol.98
, pp. 296-302
-
-
Vaux, E.C.1
Metzen, E.2
Yeates, K.M.3
Ratcliffe, P.J.4
-
52
-
-
0035933716
-
Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway
-
Srinivas V, Leshchinsky I, Sang N, King MP, Minchenko A, Caro J. Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway. J Biol Chem 2001; 276:21995-21998.
-
(2001)
J Biol Chem
, vol.276
, pp. 21995-21998
-
-
Srinivas, V.1
Leshchinsky, I.2
Sang, N.3
King, M.P.4
Minchenko, A.5
Caro, J.6
-
53
-
-
0028244438
-
Positive and negative regulation of the erythropoietin gene
-
Imagawa S, Izumi T, Miura Y. Positive and negative regulation of the erythropoietin gene. J Biol Chem 1994; 269:9038-9044.
-
(1994)
J Biol Chem
, vol.269
, pp. 9038-9044
-
-
Imagawa, S.1
Izumi, T.2
Miura, Y.3
-
54
-
-
0031043063
-
Negative regulation of the erythropoietin gene expression by the GATA transcription factors
-
Imagawa S, Yamamoto M, Miura Y. Negative regulation of the erythropoietin gene expression by the GATA transcription factors. Blood 1997; 89:1430-1439.
-
(1997)
Blood
, vol.89
, pp. 1430-1439
-
-
Imagawa, S.1
Yamamoto, M.2
Miura, Y.3
-
55
-
-
0027241363
-
The human erythropoietin-encoding gene contains a CAAT box, TATA boxes and other transcriptional regulatory elements in its 50 flanking region
-
Lee HS, Lin JJ, Kung HF, Huang PL, Lee L, Huang PL. The human erythropoietin-encoding gene contains a CAAT box, TATA boxes and other transcriptional regulatory elements in its 50 flanking region. Gene 1993; 128:227-236.
-
(1993)
Gene
, vol.128
, pp. 227-236
-
-
Lee, H.S.1
Lin, J.J.2
Kung, H.F.3
Huang, P.L.4
Lee, L.5
Huang, P.L.6
-
56
-
-
0036832772
-
Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kB
-
La Ferla K, Reimann C, Jelkmann W, Hellwig-Bürgel T. Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kB. FASEB J 2002; 16:1811-1813.
-
(2002)
FASEB J
, vol.16
, pp. 1811-1813
-
-
La Ferla, K.1
Reimann, C.2
Jelkmann, W.3
Hellwig-Bürgel, T.4
-
57
-
-
0033001379
-
Tumor necrosis factor p55 receptor (TNF-RI) mediates the in vitro inhibition of hepatic erythropoietin production
-
Jelkmann W, Hellwig-Buergel T. Tumor necrosis factor p55 receptor (TNF-RI) mediates the in vitro inhibition of hepatic erythropoietin production. Exp Hematol 1999; 27:224-228.
-
(1999)
Exp Hematol
, vol.27
, pp. 224-228
-
-
Jelkmann, W.1
Hellwig-Buergel, T.2
-
58
-
-
0036882343
-
NF-kB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression
-
Figueroa YG, Chan AK, Ibrahim R, Tang Y, Burow ME, Alam J, Scandurro AB, Beckman BS. NF-kB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression. Exp Hematol 2002; 30:1419-1427.
-
(2002)
Exp Hematol
, vol.30
, pp. 1419-1427
-
-
Figueroa, Y.G.1
Chan, A.K.2
Ibrahim, R.3
Tang, Y.4
Burow, M.E.5
Alam, J.6
Scandurro, A.B.7
Beckman, B.S.8
-
59
-
-
0024322837
-
Quantitation of erythropoietin-producing cells in kidneys of mice by in situ hybridization: Correlation with hematocrit, renal erythropoietin mRNA, and serum erythropoietin concentration
-
Koury ST, Koury MJ, Bondurant MC, Caro J, Graber SE. Quantitation of erythropoietin-producing cells in kidneys of mice by in situ hybridization: correlation with hematocrit, renal erythropoietin mRNA, and serum erythropoietin concentration. Blood 1989; 74:645-651.
-
(1989)
Blood
, vol.74
, pp. 645-651
-
-
Koury, S.T.1
Koury, M.J.2
Bondurant, M.C.3
Caro, J.4
Graber, S.E.5
-
60
-
-
0024253443
-
A comparison of the effects of renal artery constriction and anemia on the production of erythropoietin
-
Pagel H, Jelkmann W, Weiss C. A comparison of the effects of renal artery constriction and anemia on the production of erythropoietin. Pflugers Arch 1988; 413:62-66.
-
(1988)
Pflugers Arch
, vol.413
, pp. 62-66
-
-
Pagel, H.1
Jelkmann, W.2
Weiss, C.3
-
61
-
-
0013877501
-
The central nervous system in regulation of erythropoiesis
-
Halvorsen S. The central nervous system in regulation of erythropoiesis. Acta Haematol 1966; 35:65-79.
-
(1966)
Acta Haematol
, vol.35
, pp. 65-79
-
-
Halvorsen, S.1
-
62
-
-
0014433970
-
Extra-renal and renal control of erythropoietin production
-
Mirand EA. Extra-renal and renal control of erythropoietin production. Ann N Y Acad Sci 1968; 149:94-106.
-
(1968)
Ann N Y Acad Sci
, vol.149
, pp. 94-106
-
-
Mirand, E.A.1
-
63
-
-
0024515126
-
Circadian rhythm of erythropoietin in human serum
-
Wide L, Bengtsson C, Birgegard G. Circadian rhythm of erythropoietin in human serum. Br J Haematol 1989; 72:85-90.
-
(1989)
Br J Haematol
, vol.72
, pp. 85-90
-
-
Wide, L.1
Bengtsson, C.2
Birgegard, G.3
-
64
-
-
0030070702
-
Diurnal variations of serum erythropoietin at sea level and altitude
-
Klausen T, Poulsen TD, Fogh-Andersen N, Richalet JP, Nielsen OJ, Olsen NV. Diurnal variations of serum erythropoietin at sea level and altitude. Eur J Appl Physiol Occup Physiol 1996; 72:297-302.
-
(1996)
Eur J Appl Physiol Occup Physiol
, vol.72
, pp. 297-302
-
-
Klausen, T.1
Poulsen, T.D.2
Fogh-Andersen, N.3
Richalet, J.P.4
Nielsen, O.J.5
Olsen, N.V.6
-
65
-
-
0030734731
-
Erythropoietin: Physiology and pharmacology update
-
Fisher JW. Erythropoietin: physiology and pharmacology update. Proc Soc Exp Biol Med 2003; 216:358-369.
-
(2003)
Proc Soc Exp Biol Med
, vol.216
, pp. 358-369
-
-
Fisher, J.W.1
-
66
-
-
0032520980
-
Red blood cell precursor mass as an independent determinant of serum erythropoietin level
-
Cazzola M, Guarnone R, Cerani P, Centenara E, Rovati A, Beguin Y. Red blood cell precursor mass as an independent determinant of serum erythropoietin level. Blood 1998; 91:2139-2145.
-
(1998)
Blood
, vol.91
, pp. 2139-2145
-
-
Cazzola, M.1
Guarnone, R.2
Cerani, P.3
Centenara, E.4
Rovati, A.5
Beguin, Y.6
-
67
-
-
0021270306
-
Effects of oxygen inhalation on endogenous erythropoietin kinetics, erythropoiesis, and properties of blood cells in sickle-cell anemia
-
Embury SH, Garcia JF, Mohandas N, Pennathur DR, Clark MR. Effects of oxygen inhalation on endogenous erythropoietin kinetics, erythropoiesis, and properties of blood cells in sickle-cell anemia. N Engl J Med 1984; 311:291-295.
-
(1984)
N Engl J Med
, vol.311
, pp. 291-295
-
-
Embury, S.H.1
Garcia, J.F.2
Mohandas, N.3
Pennathur, D.R.4
Clark, M.R.5
-
68
-
-
0032693972
-
Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins
-
Weikert S, Papac D, Briggs J, Cowfer D, Tom S, Gawlitzek M, Lofgren J, Mehta S, Chisholm V, Modi N, Eppler S, Carroll K, Chamow S, Peers D, Berman P, Krummen L. Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins. Nature Biotechnol 1999; 17:1116-1121.
-
(1999)
Nature Biotechnol
, vol.17
, pp. 1116-1121
-
-
Weikert, S.1
Papac, D.2
Briggs, J.3
Cowfer, D.4
Tom, S.5
Gawlitzek, M.6
Lofgren, J.7
Mehta, S.8
Chisholm, V.9
Modi, N.10
Eppler, S.11
Carroll, K.12
Chamow, S.13
Peers, D.14
Berman, P.15
Krummen, L.16
-
69
-
-
0015491311
-
The second international reference preparation of erythropoietin, human, urinary, for bioassay
-
Annable L, Cotes PM, Mussett MV. The second international reference preparation of erythropoietin, human, urinary, for bioassay. Bull World Health Organ 1972; 47:99-112.
-
(1972)
Bull World Health Organ
, vol.47
, pp. 99-112
-
-
Annable, L.1
Cotes, P.M.2
Mussett, M.V.3
-
70
-
-
0026786258
-
The International Standard for Recombinant DNA-derived Erythropoietin: Collaborative study of four recombinant DNA-derived erythropoietins and two highly purified human urinary erythropoietins
-
Storring PL, Gaines DR. The International Standard for Recombinant DNA-derived Erythropoietin: collaborative study of four recombinant DNA-derived erythropoietins and two highly purified human urinary erythropoietins. J Endocrinol 1992; 134:459-484.
-
(1992)
J Endocrinol
, vol.134
, pp. 459-484
-
-
Storring, P.L.1
Gaines, D.R.2
-
71
-
-
4644229227
-
Biochemistry and assays of Epo
-
Jelkmann W, ed, Johnson City, TN: FP Graham Publishing Co
-
Jelkmann W. Biochemistry and assays of Epo. In: Jelkmann W, ed. Erythropoietin: Molecular Biology and Clinical Use. Johnson City, TN: FP Graham Publishing Co., 2003:35-63.
-
(2003)
Erythropoietin: Molecular Biology and Clinical Use
, pp. 35-63
-
-
Jelkmann, W.1
-
72
-
-
0025276054
-
Treatment of the anemia of chronic renal failure with recombinant human erythropoietin
-
Adamson JW, Eschbach JW. Treatment of the anemia of chronic renal failure with recombinant human erythropoietin. Annu Rev Med 1990; 41:349-360.
-
(1990)
Annu Rev Med
, vol.41
, pp. 349-360
-
-
Adamson, J.W.1
Eschbach, J.W.2
-
73
-
-
0026760450
-
Progress in understanding the pathogenesis of the anemia of chronic disease
-
Means RT, Krantz SB. Progress in understanding the pathogenesis of the anemia of chronic disease. Blood 1992; 80:1639-1647.
-
(1992)
Blood
, vol.80
, pp. 1639-1647
-
-
Means, R.T.1
Krantz, S.B.2
-
74
-
-
0031821059
-
Proinflammatory cytokines lowering erythropoietin production
-
Jelkmann W. Proinflammatory cytokines lowering erythropoietin production. J Interferon Cytokine Res 1998; 18:555-559.
-
(1998)
J Interferon Cytokine Res
, vol.18
, pp. 555-559
-
-
Jelkmann, W.1
-
75
-
-
0034643632
-
The blood in systemic disorders
-
Spivak JL. The blood in systemic disorders. Lancet 2000; 355:1707-1712.
-
(2000)
Lancet
, vol.355
, pp. 1707-1712
-
-
Spivak, J.L.1
-
76
-
-
0026561396
-
New tools for clinical evaluation of erythron function in man
-
Cazzola M, Beguin Y. New tools for clinical evaluation of erythron function in man. Br J Haematol 1992; 80:278-284.
-
(1992)
Br J Haematol
, vol.80
, pp. 278-284
-
-
Cazzola, M.1
Beguin, Y.2
-
77
-
-
0027524551
-
Early prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen
-
Beguin Y, Loo M, R’Zik S, Sautois B, Lejeune F, Rorive G, Fillet G. Early prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen. Blood 1993; 82:2010-2016.
-
(1993)
Blood
, vol.82
, pp. 2010-2016
-
-
Beguin, Y.1
Loo, M.2
R’Zik, S.3
Sautois, B.4
Lejeune, F.5
Rorive, G.6
Fillet, G.7
-
78
-
-
0025123918
-
Erythropoietin receptor. Subunit structure and activation
-
D’Andrea AD, Zon LI. Erythropoietin receptor. Subunit structure and activation. J Clin Invest 1990; 86:681-687.
-
(1990)
J Clin Invest
, vol.86
, pp. 681-687
-
-
D’Andrea, A.D.1
Zon, L.I.2
-
79
-
-
0027309460
-
Structure, function, and activation of the erythropoietin receptor
-
Youssoufian H, Longmore G, Neumann D, Yoshimura A, Lodish HF. Structure, function, and activation of the erythropoietin receptor. Blood 1993; 81:2223-2236.
-
(1993)
Blood
, vol.81
, pp. 2223-2236
-
-
Youssoufian, H.1
Longmore, G.2
Neumann, D.3
Yoshimura, A.4
Lodish, H.F.5
-
80
-
-
0033548259
-
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation
-
Livnah O, Stura EA, Middleton SA, Johnson DL, Jolliffe LK, Wilson IA. Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science 1999; 283:987-990.
-
(1999)
Science
, vol.283
, pp. 987-990
-
-
Livnah, O.1
Stura, E.A.2
Middleton, S.A.3
Johnson, D.L.4
Jolliffe, L.K.5
Wilson, I.A.6
-
81
-
-
0033548048
-
Erythropoietin receptor activation by a ligand-induced conformation change
-
Remy I, Wilson IA, Michnick SW. Erythropoietin receptor activation by a ligand-induced conformation change. Science 1999; 283:990-993.
-
(1999)
Science
, vol.283
, pp. 990-993
-
-
Remy, I.1
Wilson, I.A.2
Michnick, S.W.3
-
82
-
-
0027327484
-
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
-
Witthuhn BA, Quelle FW, Silvennoinen O, Yi T, Tang B, Miura O, Ihle JN. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell 1993; 74:227-236.
-
(1993)
Cell
, vol.74
, pp. 227-236
-
-
Witthuhn, B.A.1
Quelle, F.W.2
Silvennoinen, O.3
Yi, T.4
Tang, B.5
Miura, O.6
Ihle, J.N.7
-
83
-
-
0030709473
-
The role of tyrosine phosphorylation in proliferation and maturation of erythroid progenitor cells-signals emanating from the erythropoietin receptor
-
Klingmuller U. The role of tyrosine phosphorylation in proliferation and maturation of erythroid progenitor cells-signals emanating from the erythropoietin receptor. Eur J Biochem 1997; 249:637-647.
-
(1997)
Eur J Biochem
, vol.249
, pp. 637-647
-
-
Klingmuller, U.1
-
84
-
-
0035102191
-
The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif
-
Constantinescu SN, Huang LJ, Nam H, Lodish HF. The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif. Mol Cell 2001; 7:377-385.
-
(2001)
Mol Cell
, vol.7
, pp. 377-385
-
-
Constantinescu, S.N.1
Huang, L.J.2
Nam, H.3
Lodish, H.F.4
-
85
-
-
0028852393
-
Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: Identification of potential binding sites
-
Yi T, Zhang J, Miura O, Ihle JN. Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: identification of potential binding sites. Blood 1995; 85:87-95.
-
(1995)
Blood
, vol.85
, pp. 87-95
-
-
Yi, T.1
Zhang, J.2
Miura, O.3
Ihle, J.N.4
-
86
-
-
0028956353
-
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
-
Klingmuller U, Lorenz U, Cantley LC, Neel BG, Lodish HF. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 1995; 80:729-738.
-
(1995)
Cell
, vol.80
, pp. 729-738
-
-
Klingmuller, U.1
Lorenz, U.2
Cantley, L.C.3
Neel, B.G.4
Lodish, H.F.5
-
87
-
-
0034839931
-
Genetic heterogeneity of primary familial and congenital polycythemia
-
Kralovics R, Prchal JT. Genetic heterogeneity of primary familial and congenital polycythemia. Am J Hematol 2001; 68:115-121.
-
(2001)
Am J Hematol
, vol.68
, pp. 115-121
-
-
Kralovics, R.1
Prchal, J.T.2
-
88
-
-
0036786352
-
Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality
-
Suzuki N, Ohneda O, Takahashi S, Higuchi M, Mukai HY, Nakahata T, Imagawa S, Yamamoto M. Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality. Blood 2002; 100:2279-2288.
-
(2002)
Blood
, vol.100
, pp. 2279-2288
-
-
Suzuki, N.1
Ohneda, O.2
Takahashi, S.3
Higuchi, M.4
Mukai, H.Y.5
Nakahata, T.6
Imagawa, S.7
Yamamoto, M.8
-
89
-
-
0027436101
-
Serum form of the erythropoietin receptor identified by a sequencespecific peptide antibody
-
Baynes RD, Reddy GK, Shih YJ, Skikne BS, Cook JD. Serum form of the erythropoietin receptor identified by a sequencespecific peptide antibody. Blood 1993; 82:2088-2095.
-
(1993)
Blood
, vol.82
, pp. 2088-2095
-
-
Baynes, R.D.1
Reddy, G.K.2
Shih, Y.J.3
Skikne, B.S.4
Cook, J.D.5
-
90
-
-
0029914394
-
Enzyme-linked immunosorbent assay detects a potential soluble form of the erythropoietin receptor in human plasma
-
Harris KW, Winkelmann JC. Enzyme-linked immunosorbent assay detects a potential soluble form of the erythropoietin receptor in human plasma. Am J Hematol 1996; 52:8-13.
-
(1996)
Am J Hematol
, vol.52
, pp. 8-13
-
-
Harris, K.W.1
Winkelmann, J.C.2
-
91
-
-
0027049472
-
The molecular mechanism of erythropoietin action
-
Koury MJ, Bondurant MC. The molecular mechanism of erythropoietin action. Eur J Biochem 1992; 210:649-663.
-
(1992)
Eur J Biochem
, vol.210
, pp. 649-663
-
-
Koury, M.J.1
Bondurant, M.C.2
-
92
-
-
0033619265
-
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1
-
De Maria R, Zeuner A, Eramo A, Domenichelli C, Bonci D, Grignani F, Srinivasula SM, Alnemri ES, Testa U, Peschle C. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature 1999; 401:489-493.
-
(1999)
Nature
, vol.401
, pp. 489-493
-
-
De Maria, R.1
Zeuner, A.2
Eramo, A.3
Domenichelli, C.4
Bonci, D.5
Grignani, F.6
Srinivasula, S.M.7
Alnemri, E.S.8
Testa, U.9
Peschle, C.10
-
93
-
-
0037114625
-
Polycythemia vera: Myths, mechanisms, and management
-
Spivak JL. Polycythemia vera: myths, mechanisms, and management. Blood 2002; 100:4272-4290.
-
(2002)
Blood
, vol.100
, pp. 4272-4290
-
-
Spivak, J.L.1
-
94
-
-
0035669505
-
Idiopathic erythrocytosis-a declining entity
-
Blacklock HA, Royle GA. Idiopathic erythrocytosis-a declining entity. Br J Haematol 2001; 115:774-781.
-
(2001)
Br J Haematol
, vol.115
, pp. 774-781
-
-
Blacklock, H.A.1
Royle, G.A.2
-
95
-
-
0037097562
-
Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis
-
Burns S, Arcasoy MO, Li L, Kurian E, Selander K, Emanuel PD, Harris KW. Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis. Blood 2002; 99:4400-4405.
-
(2002)
Blood
, vol.99
, pp. 4400-4405
-
-
Burns, S.1
Arcasoy, M.O.2
Li, L.3
Kurian, E.4
Selander, K.5
Emanuel, P.D.6
Harris, K.W.7
-
96
-
-
0036189341
-
Effects of losartan or enalapril on hemoglobin, circulating erythropoietin, and insulin-like growth factor-1 in patients with and without posttransplant erythrocytosis
-
Wang AY-M, Yu AW-Y, Lam CW-K, Yu LM, Li PK-T, Goh J, Lui SF. Effects of losartan or enalapril on hemoglobin, circulating erythropoietin, and insulin-like growth factor-1 in patients with and without posttransplant erythrocytosis. Am J Kidney Dis 2002; 39:600-608.
-
(2002)
Am J Kidney Dis
, vol.39
, pp. 600-608
-
-
Wang, A.Y.-M.1
Yu, A.W.-Y.2
Lam, C.W.-K.3
Yu, L.M.4
Li, P.K.-T.5
Goh, J.6
Lui, S.F.7
-
97
-
-
0037160736
-
Angiotensin-convertingenzyme inhibition therapy in altitude polycythaemia: A prospective randomised trial
-
Plata R, Cornejo A, Arratia C, Anabaya A, Perna A, Dimitrov BD, Remuzzi G, Ruggenenti P. Angiotensin-convertingenzyme inhibition therapy in altitude polycythaemia: a prospective randomised trial. Lancet 2002; 359:663-666.
-
(2002)
Lancet
, vol.359
, pp. 663-666
-
-
Plata, R.1
Cornejo, A.2
Arratia, C.3
Anabaya, A.4
Perna, A.5
Dimitrov, B.D.6
Remuzzi, G.7
Ruggenenti, P.8
-
98
-
-
0034232059
-
Use of recombinant human erythropoietin as an antianemic and performance enhancing drug
-
Jelkmann W. Use of recombinant human erythropoietin as an antianemic and performance enhancing drug. Curr Pharmaceut Biotechnol 2000; 1:11-31.
-
(2000)
Curr Pharmaceut Biotechnol
, vol.1
, pp. 11-31
-
-
Jelkmann, W.1
-
99
-
-
0037102975
-
Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy
-
Crawford J, Cella D, Cleeland CS, Cremieux PY, Demetri GD, Sarokhan BJ, Slavin MB, Glaspy JA. Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy. Cancer 2002; 95:888-895.
-
(2002)
Cancer
, vol.95
, pp. 888-895
-
-
Crawford, J.1
Cella, D.2
Cleeland, C.S.3
Cremieux, P.Y.4
Demetri, G.D.5
Sarokhan, B.J.6
Slavin, M.B.7
Glaspy, J.A.8
-
100
-
-
0030717635
-
Increased potency of an erythropoietin peptide mimetic through covalent dimerization
-
Wrighton NC, Balasubramanian P, Barbone FP, Kashyap AK, Farrell FX, Jolliffe LK, Barrett RW, Dower WJ. Increased potency of an erythropoietin peptide mimetic through covalent dimerization. Nat Biotechnol 1997; 15:1261-1265.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 1261-1265
-
-
Wrighton, N.C.1
Balasubramanian, P.2
Barbone, F.P.3
Kashyap, A.K.4
Farrell, F.X.5
Jolliffe, L.K.6
Barrett, R.W.7
Dower, W.J.8
-
101
-
-
13044262566
-
Mimicry of erythropoietin by a nonpeptide molecule
-
Qureshi SA, Kim RM, Konteatis Z, Biazzo DE, Motamedi H, Rodrigues R, Boice JA, Calaycay JR, Bednarek MA, Griffin P, Gao YD, Chapman K, Mark DF. Mimicry of erythropoietin by a nonpeptide molecule. Proc Natl Acad Sci USA 1999; 96:12156-12161.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12156-12161
-
-
Qureshi, S.A.1
Kim, R.M.2
Konteatis, Z.3
Biazzo, D.E.4
Motamedi, H.5
Rodrigues, R.6
Boice, J.A.7
Calaycay, J.R.8
Bednarek, M.A.9
Griffin, P.10
Gao, Y.D.11
Chapman, K.12
Mark, D.F.13
-
102
-
-
0037196281
-
Erythropoietin mimetics derived from solution phase combinatorial libraries
-
Goldberg J, Jin Q, Ambroise Y, Satoh S, Desharnais J, Capps K, Boger DL. Erythropoietin mimetics derived from solution phase combinatorial libraries. J Am Chem Soc 2002; 124:544-555.
-
(2002)
J Am Chem Soc
, vol.124
, pp. 544-555
-
-
Goldberg, J.1
Jin, Q.2
Ambroise, Y.3
Satoh, S.4
Desharnais, J.5
Capps, K.6
Boger, D.L.7
-
103
-
-
0034663153
-
Epolones induce erythropoietin expression via hypoxiainducible factor-1 alpha activation
-
Wanner RM, Spielmann P, Stroka DM, Camenisch G, Camenisch I, Scheid A, Houck DR, Bauer C, Gassmann M, Wenger RH. Epolones induce erythropoietin expression via hypoxiainducible factor-1 alpha activation. Blood 2000; 96:1558-1565.
-
(2000)
Blood
, vol.96
, pp. 1558-1565
-
-
Wanner, R.M.1
Spielmann, P.2
Stroka, D.M.3
Camenisch, G.4
Camenisch, I.5
Scheid, A.6
Houck, D.R.7
Bauer, C.8
Gassmann, M.9
Wenger, R.H.10
-
104
-
-
0033894551
-
Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans
-
Ren X, Dorrington KL, Maxwell PH, Robbins PA. Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans. J Appl Physiol 2000; 89:680-686.
-
(2000)
J Appl Physiol
, vol.89
, pp. 680-686
-
-
Ren, X.1
Dorrington, K.L.2
Maxwell, P.H.3
Robbins, P.A.4
-
105
-
-
0029823102
-
Iron deprivation increases erythropoietin production in vitro, in normal subjects and patients with malignancy
-
Kling PJ, Dragsten PR, Roberts RA, Dos-Santos B, Brooks DJ, Hedlund BE, Taetle R. Iron deprivation increases erythropoietin production in vitro, in normal subjects and patients with malignancy. Br J Haematol 1996; 95:241-248.
-
(1996)
Br J Haematol
, vol.95
, pp. 241-248
-
-
Kling, P.J.1
Dragsten, P.R.2
Roberts, R.A.3
Dos-Santos, B.4
Brooks, D.J.5
Hedlund, B.E.6
Taetle, R.7
-
106
-
-
0032917597
-
New epoetin mole- cules and novel therapeutic approaches
-
Barbone FP, Johnson DL, Farrell FX, Collins A, Middleton SA, McMahon FJ, Tullai J, Jolliffe LK. New epoetin mole- cules and novel therapeutic approaches. Nephrol Dial Transplant 1999; 14(suppl 2):80-84.
-
(1999)
Nephrol Dial Transplant
, vol.14
, pp. 80-84
-
-
Barbone, F.P.1
Johnson, D.L.2
Farrell, F.X.3
Collins, A.4
Middleton, S.A.5
McMahon, F.J.6
Tullai, J.7
Jolliffe, L.K.8
-
107
-
-
0035574556
-
Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo
-
Bartholomew A, Patil S, Mackay A, Nelson M, Buyaner D, Hardy W, Mosca J, Sturgeon C, Siatskas M, Mahmud N, Ferrer K, Deans R, Moseley A, Hoffman R, Devine SM. Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo. Hum Gene Ther 2001; 12:1527-1541.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1527-1541
-
-
Bartholomew, A.1
Patil, S.2
Mackay, A.3
Nelson, M.4
Buyaner, D.5
Hardy, W.6
Mosca, J.7
Sturgeon, C.8
Siatskas, M.9
Mahmud, N.10
Ferrer, K.11
Deans, R.12
Moseley, A.13
Hoffman, R.14
Devine, S.M.15
-
108
-
-
0036378210
-
Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia
-
Rinsch C, Dupraz P, Schneider BL, Déglon N, Maxwell PH, Ratcliffe PJ, Aebischer P. Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia. Kidney Int 2002; 62:1395-1401.
-
(2002)
Kidney Int
, vol.62
, pp. 1395-1401
-
-
Rinsch, C.1
Dupraz, P.2
Schneider, B.L.3
Déglon, N.4
Maxwell, P.H.5
Ratcliffe, P.J.6
Aebischer, P.7
-
109
-
-
0024046959
-
Hormones that stimulate the growth of blood cells
-
Golde DW, Gasson JC. Hormones that stimulate the growth of blood cells. Sci Am 1988; 259:62-71.
-
(1988)
Sci Am
, vol.259
, pp. 62-71
-
-
Golde, D.W.1
Gasson, J.C.2
-
110
-
-
0031873502
-
Pathogenesis of anaemia in the critically ill patient
-
Schobersberger W, Hobisch-Hagen P, Fuchs D, Hoffmann G, Jelkmann W. Pathogenesis of anaemia in the critically ill patient. Clin Intens Care 1998; 9:111-117.
-
(1998)
Clin Intens Care
, vol.9
, pp. 111-117
-
-
Schobersberger, W.1
Hobisch-Hagen, P.2
Fuchs, D.3
Hoffmann, G.4
Jelkmann, W.5
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