-
1
-
-
0037032455
-
Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance
-
Esposito G, Vitagliano L, Santamaria R, Viola A, Zagari A, Salvatore F. Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance. FEBS Lett 2002;531:152-6.
-
(2002)
FEBS Lett
, vol.531
, pp. 152-156
-
-
Esposito, G.1
Vitagliano, L.2
Santamaria, R.3
Viola, A.4
Zagari, A.5
Salvatore, F.6
-
2
-
-
0347416709
-
Genetics of lactase persistence and lactose intolerance
-
Swallow DM. Genetics of lactase persistence and lactose intolerance. Annu Rev Genet 2003;37:197-219.
-
(2003)
Annu Rev Genet
, vol.37
, pp. 197-219
-
-
Swallow, D.M.1
-
3
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science 2001;291:1304-51.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
-
4
-
-
13844313862
-
Whole-genome patterns of common DNA variation in three human populations
-
Hinds DA, Stuve LL, Nilsen GB, et al. Whole-genome patterns of common DNA variation in three human populations. Science 2005;307:1072-9.
-
(2005)
Science
, vol.307
, pp. 1072-1079
-
-
Hinds, D.A.1
Stuve, L.L.2
Nilsen, G.B.3
-
5
-
-
0034034158
-
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
-
McLeod HL, Krynetski EY, Relling MV, Evans WE. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia. Leukemia 2000;14:567-72.
-
(2000)
Leukemia
, vol.14
, pp. 567-572
-
-
McLeod, H.L.1
Krynetski, E.Y.2
Relling, M.V.3
Evans, W.E.4
-
6
-
-
4644275047
-
Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone
-
Scheuermann TH, Keeler C, Hodsdon ME. Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone. Biochemistry 2004;43:12198-209.
-
(2004)
Biochemistry
, vol.43
, pp. 12198-12209
-
-
Scheuermann, T.H.1
Keeler, C.2
Hodsdon, M.E.3
-
7
-
-
1542314424
-
Clinical utility of thiopurine S-methyltransferase genotyping
-
Corominas H, Baiget M. Clinical utility of thiopurine S-methyltransferase genotyping. Am J Pharmacogenomics 2004;4:1-8.
-
(2004)
Am J Pharmacogenomics
, vol.4
, pp. 1-8
-
-
Corominas, H.1
Baiget, M.2
-
8
-
-
0003844776
-
-
Institute of Medicine. Washington, DC: National Academy Press
-
Institute of Medicine. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin and choline. Washington, DC: National Academy Press, 1998.
-
(1998)
Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin and Choline
-
-
-
9
-
-
18644379774
-
A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: Report of the Birth Defects Research Group
-
Brody LC, Conley M, Cox C, et al. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group. Am J Hum Genet 2002;71:1207-15.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 1207-1215
-
-
Brody, L.C.1
Conley, M.2
Cox, C.3
-
10
-
-
0036798246
-
Implications on human fertility of the 677C→T and 1298A→C polymorphisms of the MTHFR gene: Consequences of a possible genetic selection
-
Reyes-Engel A, Munoz E, Gaitan MJ, et al. Implications on human fertility of the 677C→T and 1298A→C polymorphisms of the MTHFR gene: consequences of a possible genetic selection. Mol Hum Reprod 2002;8:952-7.
-
(2002)
Mol Hum Reprod
, vol.8
, pp. 952-957
-
-
Reyes-Engel, A.1
Munoz, E.2
Gaitan, M.J.3
-
11
-
-
0344157861
-
Genetic selection and folate intake during pregnancy
-
Munoz-Moran E, Dieguez-Lucena JL, Fernandez-Arcas N, Peran-Mesa S, Reyes-Engel A. Genetic selection and folate intake during pregnancy. Lancet 1998;352:1120-1.
-
(1998)
Lancet
, vol.352
, pp. 1120-1121
-
-
Munoz-Moran, E.1
Dieguez-Lucena, J.L.2
Fernandez-Arcas, N.3
Peran-Mesa, S.4
Reyes-Engel, A.5
-
12
-
-
0343471524
-
Genetic risk factor for unexplained recurrent early pregnancy loss
-
(letter)
-
Nelen WL, Steegers EA, Eskes TK, Blom HJ. Genetic risk factor for unexplained recurrent early pregnancy loss. Lancet 1997;350:861(letter).
-
(1997)
Lancet
, vol.350
, pp. 861
-
-
Nelen, W.L.1
Steegers, E.A.2
Eskes, T.K.3
Blom, H.J.4
-
13
-
-
0031828880
-
Methylenetetrahydrofolate reductase polymorphism affects the change in homocysteine and folate concentrations resulting from low dose folic acid supplementation in women with unexplained recurrent miscarriages
-
Nelen WL, Blom HJ, Thomas CM, Steegers EA, Boers GH, Eskes TK. Methylenetetrahydrofolate reductase polymorphism affects the change in homocysteine and folate concentrations resulting from low dose folic acid supplementation in women with unexplained recurrent miscarriages. J Nutr 1998;128:1336-41.
-
(1998)
J Nutr
, vol.128
, pp. 1336-1341
-
-
Nelen, W.L.1
Blom, H.J.2
Thomas, C.M.3
Steegers, E.A.4
Boers, G.H.5
Eskes, T.K.6
-
14
-
-
0028487161
-
Human methylenetetrahydrofolate reductase: Isolation of cDNA mapping and mutation identification
-
(erratum)
-
Goyette P, Sumner JS, Milos R, et al. Human methylenetetrahydrofolate reductase: isolation of cDNA mapping and mutation identification. Nat Genet 1994;7:551(erratum).
-
(1994)
Nat Genet
, vol.7
, pp. 551
-
-
Goyette, P.1
Sumner, J.S.2
Milos, R.3
-
15
-
-
0032895522
-
The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia
-
Guenther BD, Sheppard CA, Tran P, Rozen R, Matthews RG, Ludwig ML. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia. Nat Struct Biol 1999;6:359-65.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 359-365
-
-
Guenther, B.D.1
Sheppard, C.A.2
Tran, P.3
Rozen, R.4
Matthews, R.G.5
Ludwig, M.L.6
-
16
-
-
0020539902
-
Further experience of vitamin supplementation for prevention of neural tube defect recurrences
-
Smithells RW, Nevin NC, Seller MJ, et al. Further experience of vitamin supplementation for prevention of neural tube defect recurrences. Lancet 1983;1:1027-31.
-
(1983)
Lancet
, vol.1
, pp. 1027-1031
-
-
Smithells, R.W.1
Nevin, N.C.2
Seller, M.J.3
-
17
-
-
0027080461
-
Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
-
Czeizel AE, Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992;327:1832-5.
-
(1992)
N Engl J Med
, vol.327
, pp. 1832-1835
-
-
Czeizel, A.E.1
Dudas, I.2
-
18
-
-
0025863475
-
Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
-
MRC Vitamin Study Research Group
-
Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet 1991;338:131-7.
-
(1991)
Lancet
, vol.338
, pp. 131-137
-
-
-
19
-
-
0035810968
-
Low dietary folate intake is associated with an excess incidence of acute coronary events: The Kuopio Ischemic Heart Disease Risk Factor Study
-
Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT. Low dietary folate intake is associated with an excess incidence of acute coronary events: The Kuopio Ischemic Heart Disease Risk Factor Study. Circulation 2001;103:2674-80.
-
(2001)
Circulation
, vol.103
, pp. 2674-2680
-
-
Voutilainen, S.1
Rissanen, T.H.2
Virtanen, J.3
Lakka, T.A.4
Salonen, J.T.5
-
20
-
-
0030615085
-
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
-
Ma J, Stampfer MJ, Giovannucci E, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997;57:1098-102.
-
(1997)
Cancer Res
, vol.57
, pp. 1098-1102
-
-
Ma, J.1
Stampfer, M.J.2
Giovannucci, E.3
-
22
-
-
10544249877
-
Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
-
Leclerc D, Campeau E, Goyette P, et al. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum Mol Genet 1996;5:1867-74.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1867-1874
-
-
Leclerc, D.1
Campeau, E.2
Goyette, P.3
-
23
-
-
0033805360
-
A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia
-
Chango A, Emery-Fillon N, de Courcy GP, et al. A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol Genet Metab 2000;70:310-5.
-
(2000)
Mol Genet Metab
, vol.70
, pp. 310-315
-
-
Chango, A.1
Emery-Fillon, N.2
De Courcy, G.P.3
-
24
-
-
0037224868
-
The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans
-
Afman LA, Trijbels FJM, Blom HJ. The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans. J Nutr 2003;133:75-7.
-
(2003)
J Nutr
, vol.133
, pp. 75-77
-
-
Afman, L.A.1
Trijbels, F.J.M.2
Blom, H.J.3
-
25
-
-
0032856882
-
A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida
-
Wilson A, Platt R, Wu Q, et al. A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida. Mol Genet Metab 1999;67:317-23.
-
(1999)
Mol Genet Metab
, vol.67
, pp. 317-323
-
-
Wilson, A.1
Platt, R.2
Wu, Q.3
-
26
-
-
10744228304
-
Genetic determinants of folate and vitamin B12 metabolism: A common pathway in neural tube defect and Down syndrome?
-
Gueant JL, Gueant-Rodriguez RM, Anello G, et al. Genetic determinants of folate and vitamin B12 metabolism: a common pathway in neural tube defect and Down syndrome? Clin Chem Lab Med 2003;41:1473-7.
-
(2003)
Clin Chem Lab Med
, vol.41
, pp. 1473-1477
-
-
Gueant, J.L.1
Gueant-Rodriguez, R.M.2
Anello, G.3
-
27
-
-
0032878590
-
A polymorphism of the methionine synthase gene: Association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk
-
Ma J, Stampfer MJ, Christensen B, et al. A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 1999;8:825-9.
-
(1999)
Cancer Epidemiol Biomarkers Prev
, vol.8
, pp. 825-829
-
-
Ma, J.1
Stampfer, M.J.2
Christensen, B.3
-
28
-
-
8444222000
-
Association of vitamin D receptor gene polymorphisms with childhood and adult asthma
-
Raby BA, Lazarus R, Silverman EK, et al. Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med 2004;170:1057-65.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1057-1065
-
-
Raby, B.A.1
Lazarus, R.2
Silverman, E.K.3
-
29
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder JN, Gnirke A, Thomas W, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996;13:399-408.
-
(1996)
Nat Genet
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
-
30
-
-
0030221927
-
Mutation analysis in hereditary hemochromatosis
-
discussion 194a-b
-
Beutler E, Gelbart T, West C, et al. Mutation analysis in hereditary hemochromatosis. Blood Cells Mol Dis 1996;22:187-94; discussion 194a-b.
-
(1996)
Blood Cells Mol Dis
, vol.22
, pp. 187-194
-
-
Beutler, E.1
Gelbart, T.2
West, C.3
-
32
-
-
0005600868
-
A simple genetic test identifies 90% of UK patients with haemochromatosis
-
The UK Haemochromatosis Consortium
-
A simple genetic test identifies 90% of UK patients with haemochromatosis. The UK Haemochromatosis Consortium. Gut 1997;41:841-4.
-
(1997)
Gut
, vol.41
, pp. 841-844
-
-
-
33
-
-
0036937743
-
Association found between the promoter region polymorphism in the apolipoprotein A-V gene and the serum triglyceride level in Japanese schoolchildren
-
Endo K, Yanagi H, Araki J, Hirano C, Yamakawa-Kobayashi K, Tomura S. Association found between the promoter region polymorphism in the apolipoprotein A-V gene and the serum triglyceride level in Japanese schoolchildren. Hum Genet 2002;111:570-2.
-
(2002)
Hum Genet
, vol.111
, pp. 570-572
-
-
Endo, K.1
Yanagi, H.2
Araki, J.3
Hirano, C.4
Yamakawa-Kobayashi, K.5
Tomura, S.6
-
34
-
-
5144231856
-
The -1131T→C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men
-
Jang Y, Kim JY, Kim OY, et al. The -1131T→C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men. Am J Clin Nutr 2004;80:832-40.
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 832-840
-
-
Jang, Y.1
Kim, J.Y.2
Kim, O.Y.3
-
35
-
-
0344061508
-
Mild association between the A/G polymorphism in the promoter of the apolipoprotein A-I gene and apolipoprotein A-I levels: A meta-analysis
-
Juo SH, Wyszynski DF, Beaty TH, Huang HY, Bailey-Wilson JE. Mild association between the A/G polymorphism in the promoter of the apolipoprotein A-I gene and apolipoprotein A-I levels: a meta-analysis. Am J Med Genet 1999;82:235-41.
-
(1999)
Am J Med Genet
, vol.82
, pp. 235-241
-
-
Juo, S.H.1
Wyszynski, D.F.2
Beaty, T.H.3
Huang, H.Y.4
Bailey-Wilson, J.E.5
-
36
-
-
0141841622
-
A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia
-
Kao JT, Wen HC, Chien KL, Hsu HC, Lin SW. A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia. Hum Mol Genet 2003;12:2533-9.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2533-2539
-
-
Kao, J.T.1
Wen, H.C.2
Chien, K.L.3
Hsu, H.C.4
Lin, S.W.5
-
37
-
-
0032968125
-
Compound heterozygosity for an apolipoprotein A1 gene promoter mutation and a structural nonsense mutation with apolipoprotein A1 deficiency
-
Matsunaga A, Sasaki J, Han H, et al. Compound heterozygosity for an apolipoprotein A1 gene promoter mutation and a structural nonsense mutation with apolipoprotein A1 deficiency. Arterioscler Thromb Vasc Biol 1999;19:348-355.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 348-355
-
-
Matsunaga, A.1
Sasaki, J.2
Han, H.3
-
38
-
-
0022543084
-
Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism
-
Bosron WF, Li TK. Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 1986;6:502-10.
-
(1986)
Hepatology
, vol.6
, pp. 502-510
-
-
Bosron, W.F.1
Li, T.K.2
-
39
-
-
4644221542
-
Natural selection: Sign, sign, everywhere a sign
-
Wooding S. Natural selection: sign, sign, everywhere a sign. Curr Biol 2004;14:R700-1.
-
(2004)
Curr Biol
, vol.14
-
-
Wooding, S.1
-
40
-
-
0037340998
-
PopHist: Inferring population history from the spectrum of allele frequencies
-
Wooding S. PopHist: inferring population history from the spectrum of allele frequencies. Bioinformatics 2003;19:539-40.
-
(2003)
Bioinformatics
, vol.19
, pp. 539-540
-
-
Wooding, S.1
-
41
-
-
8844227502
-
Population history and natural selection shape patterns of genetic variation in 132 genes
-
Internet
-
Akey JM, Eberle MA, Rieder MJ, et al. Population history and natural selection shape patterns of genetic variation in 132 genes. PLoS Biol [serial online] 2004;2:e286 (Internet: http://biology.plosjournals.org/perlserv/? request=get-document&doi=10.1371/journal.pbio.0020286).
-
(2004)
PLoS Biol [Serial Online]
, vol.2
-
-
Akey, J.M.1
Eberle, M.A.2
Rieder, M.J.3
-
42
-
-
0036274917
-
The genetic consequences of our sweet tooth
-
Cox TM. The genetic consequences of our sweet tooth. Nat Rev Genet 2002;3:481-7.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 481-487
-
-
Cox, T.M.1
-
43
-
-
0036855185
-
Abundant raw material for cis-regulatory evolution in humans
-
Rockman MV, Wray GA. Abundant raw material for cis-regulatory evolution in humans. Mol Biol Evol 2002;19:1991-2004.
-
(2002)
Mol Biol Evol
, vol.19
, pp. 1991-2004
-
-
Rockman, M.V.1
Wray, G.A.2
-
44
-
-
0042697343
-
The evolution of transcriptional regulation in eukaryotes
-
Wray GA, Hahn MW, Abouheif E, et al. The evolution of transcriptional regulation in eukaryotes. Mol Biol Evol 2003;20:1377-419.
-
(2003)
Mol Biol Evol
, vol.20
, pp. 1377-1419
-
-
Wray, G.A.1
Hahn, M.W.2
Abouheif, E.3
-
45
-
-
0037307413
-
Signatures of natural selection in the human genome
-
Bamshad M, Wooding SP. Signatures of natural selection in the human genome. Nat Rev Genet 2003;4:99-111.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 99-111
-
-
Bamshad, M.1
Wooding, S.P.2
-
46
-
-
0346243805
-
Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios
-
Clark AG, Glanowski S, Nielsen R, et al. Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. Science 2003;302:1960-3.
-
(2003)
Science
, vol.302
, pp. 1960-1963
-
-
Clark, A.G.1
Glanowski, S.2
Nielsen, R.3
-
47
-
-
0033828761
-
Estimate of the mutation rate per nucleotide in humans
-
Nachman MW, Crowell SL. Estimate of the mutation rate per nucleotide in humans. Genetics 2000;156:297-304.
-
(2000)
Genetics
, vol.156
, pp. 297-304
-
-
Nachman, M.W.1
Crowell, S.L.2
-
48
-
-
0242524432
-
Patterns of human genetic diversity: Implications forhumanevolutionary history and disease
-
Tishkoff SA, Verrelli BC. Patterns of human genetic diversity: implications forhumanevolutionary history and disease. Annu Rev Genomics Hum Genet 2003;4:293-340.
-
(2003)
Annu Rev Genomics Hum Genet
, vol.4
, pp. 293-340
-
-
Tishkoff, S.A.1
Verrelli, B.C.2
-
49
-
-
0037497326
-
The double puzzle of diabetes
-
Diamond J. The double puzzle of diabetes. Nature 2003;423:599-602.
-
(2003)
Nature
, vol.423
, pp. 599-602
-
-
Diamond, J.1
-
50
-
-
0033810469
-
Single nucleotide polymorphisms and the future of genetic epidemiology
-
Schork N, Fallin D, Lanchbury JS. Single nucleotide polymorphisms and the future of genetic epidemiology. Clin Genet 2000;58:250-64.
-
(2000)
Clin Genet
, vol.58
, pp. 250-264
-
-
Schork, N.1
Fallin, D.2
Lanchbury, J.S.3
-
51
-
-
12844286905
-
Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc: Implications for inhibition of DNA replication
-
Perry C, Sastry R, Nasrallah IM, Stover PJ. Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc: implications for inhibition of DNA replication. J Biol Chem 2004;280:396-400.
-
(2004)
J Biol Chem
, vol.280
, pp. 396-400
-
-
Perry, C.1
Sastry, R.2
Nasrallah, I.M.3
Stover, P.J.4
-
53
-
-
2442677652
-
Genetic signatures of strong recent positive selection at the lactase gene
-
Bersaglieri T, Sabeti PC, Patterson N, et al Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet 2004;74:1111-20.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 1111-1120
-
-
Bersaglieri, T.1
Sabeti, P.C.2
Patterson, N.3
-
54
-
-
0141455095
-
A method for detecting recent selection in the human genome from allele age estimates
-
Toomajian C, Ajioka RS, Jorde LB, Kushner JP, Kreitman M. A method for detecting recent selection in the human genome from allele age estimates. Genetics 2003;165:287-97.
-
(2003)
Genetics
, vol.165
, pp. 287-297
-
-
Toomajian, C.1
Ajioka, R.S.2
Jorde, L.B.3
Kushner, J.P.4
Kreitman, M.5
-
55
-
-
18444412585
-
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity
-
Osier MV, Pakstis AJ, Soodyall H, et al. A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet 2002;71:84-99.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 84-99
-
-
Osier, M.V.1
Pakstis, A.J.2
Soodyall, H.3
-
56
-
-
0344620583
-
Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa
-
Pagnier J, Mears JG, Dunda-Belkhodja O, et al. Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa. Proc Natl Acad Sci U S A 1984;81:1771-3.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 1771-1773
-
-
Pagnier, J.1
Mears, J.G.2
Dunda-Belkhodja, O.3
-
57
-
-
0035919696
-
Haplotype diversity and linkage disequilibrium at human G6PD: Recent origin of alleles that confer malarial resistance
-
Tishkoff SA, Varkonyi R, Cahinhinan N, et al. Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science 2001;293:455-62.
-
(2001)
Science
, vol.293
, pp. 455-462
-
-
Tishkoff, S.A.1
Varkonyi, R.2
Cahinhinan, N.3
-
59
-
-
2442539281
-
The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer
-
Oyama K, Kawakami K, Maeda K, Ishiguro K, Watanabe G. The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer. Anticancer Res 2004;24:649-54.
-
(2004)
Anticancer Res
, vol.24
, pp. 649-654
-
-
Oyama, K.1
Kawakami, K.2
Maeda, K.3
Ishiguro, K.4
Watanabe, G.5
-
60
-
-
4444371465
-
Methylenetetrahydrofolate reductase 677C→T polymorphism affects DNA methylation in response to controlled folate intake in young women
-
Shelnutt KP, Kauwell GP, Gregory JF 3rd, et al. Methylenetetrahydrofolate reductase 677C→T polymorphism affects DNA methylation in response to controlled folate intake in young women. J Nutr Biochem 2004;15:554-60.
-
(2004)
J Nutr Biochem
, vol.15
, pp. 554-560
-
-
Shelnutt, K.P.1
Kauwell, G.P.2
Gregory III, J.F.3
-
61
-
-
20144371859
-
Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides
-
Quinlivan EP, Davis SR, Shelnutt KP, et al. Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides. J Nutr 2005;135:389-96.
-
(2005)
J Nutr
, vol.135
, pp. 389-396
-
-
Quinlivan, E.P.1
Davis, S.R.2
Shelnutt, K.P.3
-
62
-
-
0030615085
-
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
-
Ma J, Stampfer MJ, Giovannucci E, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997;57:1098-102.
-
(1997)
Cancer Res
, vol.57
, pp. 1098-1102
-
-
Ma, J.1
Stampfer, M.J.2
Giovannucci, E.3
-
63
-
-
0031961002
-
Worldwide distribution of a common methylenetetrahydrofolate reductase mutation
-
Schneider JA, Rees DC, Liu YT, Clegg JB. Worldwide distribution of a common methylenetetrahydrofolate reductase mutation. Am J Hum Genet 1998;62:1258-60.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1258-1260
-
-
Schneider, J.A.1
Rees, D.C.2
Liu, Y.T.3
Clegg, J.B.4
-
64
-
-
0343503018
-
High prevalence of the thermolabile methylenetetrahydrofolate reductase variant in Mexico: A country with a very high prevalence of neural tube defects
-
Mutchinick OM, Lopez MA, Luna L, Waxman J, Babinsky VE. High prevalence of the thermolabile methylenetetrahydrofolate reductase variant in Mexico: a country with a very high prevalence of neural tube defects. Mol Genet Metab 1999;68:461-7.
-
(1999)
Mol Genet Metab
, vol.68
, pp. 461-467
-
-
Mutchinick, O.M.1
Lopez, M.A.2
Luna, L.3
Waxman, J.4
Babinsky, V.E.5
-
65
-
-
2342642866
-
Differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene among the Lebanese population
-
Almawi WY, Finan RR, Tamim H, Daccache JL, Irani-Hakime N. Differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene among the Lebanese population. Am J Hematol 2004;76:85-7.
-
(2004)
Am J Hematol
, vol.76
, pp. 85-87
-
-
Almawi, W.Y.1
Finan, R.R.2
Tamim, H.3
Daccache, J.L.4
Irani-Hakime, N.5
-
66
-
-
0005775025
-
The incidence of the gene for thermolabile methylene tetrahydrofolate reductase in African Americans
-
McAndrew PE, Brandt JT, Pearl DK, Prior TW. The incidence of the gene for thermolabile methylene tetrahydrofolate reductase in African Americans. Thromb Res 1996;83:195-8.
-
(1996)
Thromb Res
, vol.83
, pp. 195-198
-
-
McAndrew, P.E.1
Brandt, J.T.2
Pearl, D.K.3
Prior, T.W.4
-
67
-
-
0031969688
-
The high prevalence of thermolabile 5-10 methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease (CAD)
-
Abbate R, Sardi I, Pepe G, et al. The high prevalence of thermolabile 5-10 methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease (CAD). Thromb Haemost 1998;79:727-30.
-
(1998)
Thromb Haemost
, vol.79
, pp. 727-730
-
-
Abbate, R.1
Sardi, I.2
Pepe, G.3
-
68
-
-
0035032925
-
Impairment of learning and memory in rats caused by oxidative stress and aging, and changes in antioxidative defense systems
-
Fukui K, Onodera K, Shinkai T, Suzuki S, Urano S. Impairment of learning and memory in rats caused by oxidative stress and aging, and changes in antioxidative defense systems. Ann N Y Acad Sci 2001;928:168-75.
-
(2001)
Ann N Y Acad Sci
, vol.928
, pp. 168-175
-
-
Fukui, K.1
Onodera, K.2
Shinkai, T.3
Suzuki, S.4
Urano, S.5
-
69
-
-
0032906750
-
Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: Metabolic significance, risks and impact on folate requirement
-
Bailey LB, Gregory JF 3rd. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr 1999;129:919-22.
-
(1999)
J Nutr
, vol.129
, pp. 919-922
-
-
Bailey, L.B.1
Gregory III, J.F.2
-
70
-
-
0038460703
-
Iron status in Danish women, 1984-1994: A cohort comparison of changes in iron stores and the prevalence of iron deficiency and iron overload
-
Milman N, Byg KE, Ovesen L, Kirchhoff M, Jurgensen KS. Iron status in Danish women, 1984-1994: a cohort comparison of changes in iron stores and the prevalence of iron deficiency and iron overload. Eur J Haematol 2003;71:51-61.
-
(2003)
Eur J Haematol
, vol.71
, pp. 51-61
-
-
Milman, N.1
Byg, K.E.2
Ovesen, L.3
Kirchhoff, M.4
Jurgensen, K.S.5
-
71
-
-
1842338009
-
The effect of withdrawal of food iron fortification in Sweden as studied with phlebotomy in subjects with genetic hemochromatosis
-
Olsson KS, Vaisanen M, Konar J, Bruce A. The effect of withdrawal of food iron fortification in Sweden as studied with phlebotomy in subjects with genetic hemochromatosis. Eur J Clin Nutr 1997;51:782-6.
-
(1997)
Eur J Clin Nutr
, vol.51
, pp. 782-786
-
-
Olsson, K.S.1
Vaisanen, M.2
Konar, J.3
Bruce, A.4
-
72
-
-
0036707789
-
HFE based re-evaluation of heterozygous hemochromatosis
-
Moirand R, Guyader D, Mendler MH, et al. HFE based re-evaluation of heterozygous hemochromatosis. Am J Med Genet 2002;111:356-61.
-
(2002)
Am J Med Genet
, vol.111
, pp. 356-361
-
-
Moirand, R.1
Guyader, D.2
Mendler, M.H.3
-
73
-
-
0036322831
-
Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring
-
Cooney CA, Dave AA, Wolff GL. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr 2002;132:2393S-400S.
-
(2002)
J Nutr
, vol.132
-
-
Cooney, C.A.1
Dave, A.A.2
Wolff, G.L.3
-
74
-
-
0043093697
-
Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
-
Waterland R, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 2003;23:5293-300.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5293-5300
-
-
Waterland, R.1
Jirtle, R.L.2
-
76
-
-
1642633864
-
Ageing: Growing old gracefully
-
Abbott A. Ageing: growing old gracefully. Nature 2004;428:116-8.
-
(2004)
Nature
, vol.428
, pp. 116-118
-
-
Abbott, A.1
-
77
-
-
0036286297
-
Micronutrients and genomic stability: A new paradigm for recommended dietary allowances (RDAs)
-
Fenech M. Micronutrients and genomic stability: a new paradigm for recommended dietary allowances (RDAs). Food Chem Toxicol 2002;40:1113-7.
-
(2002)
Food Chem Toxicol
, vol.40
, pp. 1113-1117
-
-
Fenech, M.1
-
78
-
-
0035906343
-
DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
-
Ames BN. DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res 2001;475:7-20.
-
(2001)
Mutat Res
, vol.475
, pp. 7-20
-
-
Ames, B.N.1
-
80
-
-
0034807280
-
Methylation and colorectal cancer
-
Jubb AM, Bell SM, Quirke P. Methylation and colorectal cancer. J Pathol 2001;195:111-34.
-
(2001)
J Pathol
, vol.195
, pp. 111-134
-
-
Jubb, A.M.1
Bell, S.M.2
Quirke, P.3
-
81
-
-
0027286578
-
Folate, methionine, and alcohol intake and risk of colorectal adenoma
-
Giovannucci E, Stampfer MJ, Colditz GA, et al. Folate, methionine, and alcohol intake and risk of colorectal adenoma. J Natl Cancer Inst 1993;85:875-84.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 875-884
-
-
Giovannucci, E.1
Stampfer, M.J.2
Colditz, G.A.3
-
82
-
-
0032704132
-
Folate and cancer prevention: A new medical application of folate beyond hyperhomocysteinemia and neural tube defects
-
Kim YI. Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects. Nutr Rev 1999;57:314-21.
-
(1999)
Nutr Rev
, vol.57
, pp. 314-321
-
-
Kim, Y.I.1
-
83
-
-
0021950948
-
Hypomethylation of DNA from benign and malignant human colon neoplasms
-
Goelz SE, Vogelstein B, Hamilton SR, Feinberg AP. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 1985;228:187-90.
-
(1985)
Science
, vol.228
, pp. 187-190
-
-
Goelz, S.E.1
Vogelstein, B.2
Hamilton, S.R.3
Feinberg, A.P.4
-
84
-
-
0037064008
-
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses
-
Herbig K, Chiang EP, Lee LR, Hills J, Shane B, Stover PJ. Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. J Biol Chem 2002;277:38381-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 38381-38389
-
-
Herbig, K.1
Chiang, E.P.2
Lee, L.R.3
Hills, J.4
Shane, B.5
Stover, P.J.6
-
85
-
-
0035827708
-
Heavy chain ferritin enhances serine hydroxymethyltransferase expression and de novo thymidine biosynthesis
-
Oppenheim EW, Adelman C, Liu X, Stover PJ. Heavy chain ferritin enhances serine hydroxymethyltransferase expression and de novo thymidine biosynthesis. J Biol Chem 2001;276:19855-61.
-
(2001)
J Biol Chem
, vol.276
, pp. 19855-19861
-
-
Oppenheim, E.W.1
Adelman, C.2
Liu, X.3
Stover, P.J.4
-
87
-
-
85047696639
-
Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos
-
Zetterberg H, Regland B, Palmer M, et al. Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos. Eur J Hum Genet 2002;10:113-8.
-
(2002)
Eur J Hum Genet
, vol.10
, pp. 113-118
-
-
Zetterberg, H.1
Regland, B.2
Palmer, M.3
-
88
-
-
0036129677
-
The C677T polymorphism of the methylenetetrahydrofolate reductase gene and idiopathic recurrent miscarriage
-
Unfried G, Griesmacher A, Weismuller W, Nagele F, Huber JC, Tempfer CB. The C677T polymorphism of the methylenetetrahydrofolate reductase gene and idiopathic recurrent miscarriage. Obstet Gynecol 2002;99:614-9.
-
(2002)
Obstet Gynecol
, vol.99
, pp. 614-619
-
-
Unfried, G.1
Griesmacher, A.2
Weismuller, W.3
Nagele, F.4
Huber, J.C.5
Tempfer, C.B.6
-
89
-
-
0034190659
-
5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review
-
Botto LD, Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol 2000;151:862-77.
-
(2000)
Am J Epidemiol
, vol.151
, pp. 862-877
-
-
Botto, L.D.1
Yang, Q.2
-
90
-
-
85030345384
-
Changes in MTHFR genotype frequencies over time
-
Whitehead A. Changes in MTHFR genotype frequencies over time. Lancet 1998;352:1784-5.
-
(1998)
Lancet
, vol.352
, pp. 1784-1785
-
-
Whitehead, A.1
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