Mild association between the A/G polymorphism in the promoter of the apolipoprotein A-I gene and apolipoprotein A-I levels: A meta-analysis

American Journal of Medical Genetics

Volumn 82, Issue 3, 1999, Pages 235-241

  Juo, Suh Hang Hank ^a,b   Wyszynski, Diego F ^c   Beaty, Terri H ^d   Huang, Han Yao ^d   Bailey Wilson, Joan E ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

apo A I; APOAI gene; Association study; Linkage disequilibrium; Meta analysis; Polymorphism

Indexed keywords

APOLIPOPROTEIN A1;

ALLELE; ARTICLE; DNA POLYMORPHISM; GENETIC ANALYSIS; HUMAN; META ANALYSIS; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROMOTER REGION;

ADOLESCENT; ADULT; AGED; ALLELES; APOLIPOPROTEIN A-I; CHILD; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POINT MUTATION; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SMOKING;

EID: 0344061508     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19990129)82:3<235::AID-AJMG8>3.0.CO;2-H     Document Type: Article

References (23)

1. Bai H, Asku K, Liu R, Jimi S, Arakawa K. 1996. Analysis of a new polymorphism in the human apolipoprotein A-I genes: association with serum lipoprotcin levels and coronary heart disease. J Cardiol 28:207-212.
2. Dallinga-Thie GM, Bu XD, Trip MVLS, Rotter JI, Lusis AJ, de Bruin TWA. 1996. Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: effects on LDL-cholesterol and apolipoprotein B and C-III. J Lipid Res 37:136-147.
3. Greenland S. 1987. Quantitative methods in the review of epidemiologic literature. Epidemiol Rev 9:1-30.
4. Jeenah M, Kessling A, Miller N, Humphries S. 1990. G to A substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI and high density lipoprotein cholesterol concentrations. Mol Biol Med 7:233-241.
5. Juo SH, Beaty TH, Xu J, Prenger VL, Coresh J, Kwiterovich PO Jr. 1998. Segregation analysis of two-locus models regulating apolipoprotein-A1 levels. Genet Epidemiol 10:73-86.
6. Kamboh MI, Aston CE, Nestlerode CM, McAllister AE, Hamman RE. 1996. Haplotype analysis of two APOAI/MspI polymorphisms in relation to plasma levels of Apo A-I and HDL-cholesterol. Atherosclerosis 127: 255-262.
7. Karathanasis SK, Zannis VI, Breslow JL. 1983. Isolation and characterization of the human apolipoprotein A-I gene. Proc Natl Acad Sci USA 80:6147-6151.
8. Minnich A, DeLangavant G, Lavigne J, Roederer G, Lussier-Cacan S, Davignon J. 1995. G-A substitution at position -75 of the apolipoprotein A-I gene promoter: evidence against a direct effect on HDL cholesterol levels. Arterioscler Thromb Vasc Biol 10:1740-1745.
9. Moll P, Michels W, Weidman WH, Kottke BA. 1989. Genetic determination of plasma apolipoprotein-A1 in a population-based sample. Am J Hum Genet 44:124-139.
10. Ordovas J, Civeira F, Genest J Jr, Craig S, Robbins AH, Meade T, Pocovi M, Frossard PM, Masharani U, Wilson PWF, Salem DN, Ward RH, Schaefer EJ. 1991. Restriction fragment length polymorphisms of the apolipoprotein A-I, C-III, A-IV gene locus. Atherosclerosis 87:75-86.
11. Papazafiri P, Ogami K, Ramji DP, Nicosia A, Monaci P, Cladaras C, Zannis VI. 1991. Promoter elements and factors involved in hepatic transcription of the human apoA-I gene positive and negative regulators bind to overlapping sites. J Biol Chem 266:5790-5797.
12. Paul-Hayase H, Rosseneu M, Robinson D, Van Berviet JP, Deslypere JP, Humphries SE. 1992. Polymorphisms in the apolipoprotein (apo) AI-CIII-AIV gene cluster: detection of genetic variation determining plasma apo AI, apo CIII and apo AIV concentrations. Hum Genet 88: 439-446.
13. Pujia A, Gnasso A, Siclari D, Dominijanni A, Zingone A, Marasco O, Mele E, Cortese C, Colonna A, Mattioli PL. 1994. Sst I RFLP and hypertension factors for extracoronary atherosclerosis in a male population of southern Italy. Artery 21:208-221.
14. Rader DJ, Hoeg J, Brewer B Jr. 1994. Quantitation of plasma apolipoproteins in the primary and secondary prevention of coronary artery disease. Ann Intern Med 102:1012-1025.
15. Rigoli L, Raimondo G, Di Benedetto A, Romano G, Porcellini A, Campo S, Corica F, Riccardi G, Squadrito G, Cucinotta D. 1995. Apolipoprotein AI-CIII-AIV genetic polymorphisms and coronary heart disease in type 2 diabetes mellitus. Acta Diabetol 32:251-256.
16. Saha N, Tay JSH, Low PS, Humphries SE. 1994. Guanidine to Adenine (G/A) substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI levels in Chinese non-smokers. Genet Epidemiol 11:255-264.
17. Shoulders CC, Kornblihtt AR, Munro BS, Baralle FE. 1983. Gene structure of human apolipoprotein AI. Nucleic Acids Res 11:2827-2837.
18. Sigurdsson G Jr, Gudnason V, Sigurdsson G, Humphries SE. 1992. Interaction between a polymorphism of the apoA-I promoter region and smoking determines plasma levels of HDL and apoA-I. Arterioscler Thromb 12:1017-1022.
19. Smith JD, Brinton EA, Breslow JL. 1992. Polymorphism in the human apolipoprotein A-I gene promoter region: Association of the minor allele with decreased production rate in vivo and promoter activity in vitro. J Clin Invest 89:1796-1800.
20. Talmud PJ, Ye S, Humphries S. 1994. Polymorphism in the promoter region of the apolipoprotein AI gene associated with differences in apolipoprotein AI levels: the European Atherosclerosis research study. Genet Epidemiol 11:265-280.
21. Tybjarg-Hansen A, Nordestgaard BG, Gerdes LU, Fargeman O, Humphries SE. 1993. Genetic markers in the apo AI-CIII-AIV gene cluster for combined hyperlipidemia, hypertriglyceridemia, and predisposition to atherosclerosis. Atherosclerosis 100:157-169.
22. Wang XL, Liu SX, McCredie RM, Wilcken DEL. 1996. Polymorphisms at the 5′-end of the apolipoprotein AI gene and severity of coronary artery disease. J Clin Invest 98:372-377.
23. Xu CF, Angelico F, Ben MD, Humphries S. 1993. Role of genetic variation at the apo AI-CIII-AIV gene cluster in determining plasma apo AI levels in boys and girls. Genet Epidemiol 10:113-122.