-
1
-
-
0027959330
-
Did malaria select for primary adult lactase deficiency?
-
Anderson B, Vullo C. 1994. Did malaria select for primary adult lactase deficiency? Gut 35:1487-89
-
(1994)
Gut
, vol.35
, pp. 1487-1489
-
-
Anderson, B.1
Vullo, C.2
-
2
-
-
0023890884
-
Comparison of indirect diagnostic methods for hypolactasia
-
Arola H, Koivula T, Jokela H, Jauhiainen M, Keyrilainen O, et al. 1988. Comparison of indirect diagnostic methods for hypolactasia. Scand. J. Gastroenterol. 23:351-57
-
(1988)
Scand. J. Gastroenterol.
, vol.23
, pp. 351-357
-
-
Arola, H.1
Koivula, T.2
Jokela, H.3
Jauhiainen, M.4
Keyrilainen, O.5
-
3
-
-
0034531969
-
Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase
-
Arribas JC, Herrero AG, Martin-Lomas M, Canada FJ, He S, et al. 2000. Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase. Eur. J. Biochem. 267:6996-7005
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6996-7005
-
-
Arribas, J.C.1
Herrero, A.G.2
Martin-Lomas, M.3
Canada, F.J.4
He, S.5
-
4
-
-
0001205938
-
Isolated intestinal lactase deficiency in the adult
-
Auricchio S, Rubino A, Semenza G, Landolt M, Prader A. 1963. Isolated intestinal lactase deficiency in the adult. Lancet 2:324-26
-
(1963)
Lancet
, vol.2
, pp. 324-326
-
-
Auricchio, S.1
Rubino, A.2
Semenza, G.3
Landolt, M.4
Prader, A.5
-
5
-
-
0024227252
-
Effect of lactose hydrolysis on calcium absorption during duodenal milk perfusion
-
Birlouez-Aragon I. 1988. Effect of lactose hydrolysis on calcium absorption during duodenal milk perfusion. Reprod. Nutr. Dev. 28:1465-72
-
(1988)
Reprod. Nutr. Dev.
, vol.28
, pp. 1465-1472
-
-
Birlouez-Aragon, I.1
-
6
-
-
0027259396
-
Disturbed galactose metabolism in elderly and diabetic humans is associated with cataract formation
-
Birlouez-Aragon I, Ravelontseheno L, Villate-Cathelineau B, Cathelineau G, Abitbol G. 1993. Disturbed galactose metabolism in elderly and diabetic humans is associated with cataract formation. J. Nutr. 123:1370-76
-
(1993)
J. Nutr.
, vol.123
, pp. 1370-1376
-
-
Birlouez-Aragon, I.1
Ravelontseheno, L.2
Villate-Cathelineau, B.3
Cathelineau, G.4
Abitbol, G.5
-
7
-
-
0025882118
-
Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase
-
Boll W, Wagner P, Mantei N. 1991. Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase. Am. J. Hum. Genet. 48:889-902
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 889-902
-
-
Boll, W.1
Wagner, P.2
Mantei, N.3
-
8
-
-
0010106732
-
Regulation of human lactase phlorizin hydrolase (LPH) gene by proteins binding to sites 5′ to the Alu sequence
-
Chitkara DK, Krasinski SD, Grand RJ, Montgomery RK. 2001. Regulation of human lactase phlorizin hydrolase (LPH) gene by proteins binding to sites 5′ to the Alu sequence. Gastroenterology 120:A304
-
(2001)
Gastroenterology
, vol.120
-
-
Chitkara, D.K.1
Krasinski, S.D.2
Grand, R.J.3
Montgomery, R.K.4
-
9
-
-
0142069606
-
Did persistence of intestinal lactase into adult life originate in the Arabian peninsula?
-
Cook GC. 1978. Did persistence of intestinal lactase into adult life originate in the Arabian peninsula? Man 13:418-27
-
(1978)
Man
, vol.13
, pp. 418-427
-
-
Cook, G.C.1
-
10
-
-
0016781834
-
High intestinal lactase concentrations in adult Arabs in Saudi Arabia
-
Cook GC, Al-Torki MT. 1975. High intestinal lactase concentrations in adult Arabs in Saudi Arabia. Br. Med. J. 3:135-36
-
(1975)
Br. Med. J.
, vol.3
, pp. 135-136
-
-
Cook, G.C.1
Al-Torki, M.T.2
-
11
-
-
0036083017
-
Lactose malabsorption and intolerance and peak bone mass
-
Di Stefano M, Veneto G, Malservisi S, Cecchetti L, Minguzzi L, et al. 2002. Lactose malabsorption and intolerance and peak bone mass. Gastroenterology 122:1793-99
-
(2002)
Gastroenterology
, vol.122
, pp. 1793-1799
-
-
Di Stefano, M.1
Veneto, G.2
Malservisi, S.3
Cecchetti, L.4
Minguzzi, L.5
-
12
-
-
0036479030
-
Identification of a variant associated with adult-type hypolactasia
-
Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L, et al. 2002. Identification of a variant associated with adult-type hypolactasia. Nat. Genet. 30:233-37
-
(2002)
Nat. Genet.
, vol.30
, pp. 233-237
-
-
Enattah, N.S.1
Sahi, T.2
Savilahti, E.3
Terwilliger, J.D.4
Peltonen, L.5
-
13
-
-
0026534272
-
Molecular basis of lactase levels in adult humans
-
Escher JC, De Koning N, Van Engen C, Arora S, Büller HA, et al. 1992. Molecular basis of lactase levels in adult humans. J. Clin. Invest. 89:480-83
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 480-483
-
-
Escher, J.C.1
De Koning, N.2
Van Engen, C.3
Arora, S.4
Büller, H.A.5
-
14
-
-
0028327817
-
The polymorphic expression of lactase in adults is regulated at the messenger RNA level
-
Fajardo O, Naim HY, Lacey SW. 1994. The polymorphic expression of lactase in adults is regulated at the messenger RNA level. Gastroenterology 106:1233-41
-
(1994)
Gastroenterology
, vol.106
, pp. 1233-1241
-
-
Fajardo, O.1
Naim, H.Y.2
Lacey, S.W.3
-
16
-
-
0000215804
-
On the theory of evolution under genetic and cultural transmission with application to the lactose absorption problem
-
ed. MW Feldman, Princeton: Princeton Univ. Press
-
Feldman MW, Cavalli-Svorza LL. 1989. On the theory of evolution under genetic and cultural transmission with application to the lactose absorption problem. In Mathematical Evolutionary Theory, ed. MW Feldman, pp. 145. Princeton: Princeton Univ. Press
-
(1989)
Mathematical Evolutionary Theory
, pp. 145
-
-
Feldman, M.W.1
Cavalli-Svorza, L.L.2
-
17
-
-
0031951707
-
GATA-6 stimulates a cell line-specific activation element in the human lactase promoter
-
Fitzgerald K, Bazar L, Avigan MI. 1998. GATA-6 stimulates a cell line-specific activation element in the human lactase promoter. Am. J. Physiol. 274:G314-24
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Fitzgerald, K.1
Bazar, L.2
Avigan, M.I.3
-
18
-
-
0021332361
-
Gene dosage effect on intestinal lactase activity demonstrated in vivo
-
Flatz G. 1984. Gene dosage effect on intestinal lactase activity demonstrated in vivo. Am. J. Hum. Genet. 36:306-10
-
(1984)
Am. J. Hum. Genet.
, vol.36
, pp. 306-310
-
-
Flatz, G.1
-
19
-
-
0015178343
-
Evidence against nutritional adaption to tolerance to lactase
-
Flatz G, Rotthauwe HW. 1971. Evidence against nutritional adaption to tolerance to lactase. Humangenetik 13:118-25
-
(1971)
Humangenetik
, vol.13
, pp. 118-125
-
-
Flatz, G.1
Rotthauwe, H.W.2
-
21
-
-
0023808609
-
Expression of the ABH, Lewis, related antigens on the glycoproteins of the human jejunal brush border
-
Green FR, Greenwell P, Dickson L, Griffiths B, Noades J, et al. 1988. Expression of the ABH, Lewis, related antigens on the glycoproteins of the human jejunal brush border. Subcell. Biochem. 12:119-53
-
(1988)
Subcell. Biochem.
, vol.12
, pp. 119-153
-
-
Green, F.R.1
Greenwell, P.2
Dickson, L.3
Griffiths, B.4
Noades, J.5
-
22
-
-
0023942909
-
Use of immunocytochemical analysis of a duodenal biopsy specimen to identify a carrier of ornithine transcarbamylase deficiency
-
Hamano Y, Kodama H, Fujikawa Y, Tanaka Y, Nishimura K, et al. 1988. Use of immunocytochemical analysis of a duodenal biopsy specimen to identify a carrier of ornithine transcarbamylase deficiency. New Engl. J. Med. 318:1521-23
-
(1988)
New Engl. J. Med.
, vol.318
, pp. 1521-1523
-
-
Hamano, Y.1
Kodama, H.2
Fujikawa, Y.3
Tanaka, Y.4
Nishimura, K.5
-
23
-
-
0027421312
-
Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21
-
Harvey CB, Fox MF, Jeggo PA, Mantei N, Povey S, et al. 1993. Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21. Ann. Hum. Genet. 57:179-85
-
(1993)
Ann. Hum. Genet.
, vol.57
, pp. 179-185
-
-
Harvey, C.B.1
Fox, M.F.2
Jeggo, P.A.3
Mantei, N.4
Povey, S.5
-
24
-
-
0031717707
-
Lactase haplotype frequencies in Caucasians: Association with the lactase persistence/non-persistence polymorphism
-
Harvey CB, Hollox EJ, Poulter M, Wang Y, Rossi M, et al. 1998. Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non-persistence polymorphism. Ann. Hum. Genet. 62:215-23
-
(1998)
Ann. Hum. Genet.
, vol.62
, pp. 215-223
-
-
Harvey, C.B.1
Hollox, E.J.2
Poulter, M.3
Wang, Y.4
Rossi, M.5
-
25
-
-
0028915875
-
DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region
-
Harvey CB, Pratt WS, Islam I, Whitehouse DB, Swallow DM. 1995. DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region. Eur. J. Hum. Genet. 3:27-41
-
(1995)
Eur. J. Hum. Genet.
, vol.3
, pp. 27-41
-
-
Harvey, C.B.1
Pratt, W.S.2
Islam, I.3
Whitehouse, D.B.4
Swallow, D.M.5
-
26
-
-
0030566803
-
Characterisation of a human homologue of a yeast cell division cycle gene, MCM6, located adjacent to the 5′ end of the lactase gene on chromosome 2q21
-
Harvey CB, Wang Y, Darmoul D, Phillips A, Mantei N, et al. 1996. Characterisation of a human homologue of a yeast cell division cycle gene, MCM6, located adjacent to the 5′ end of the lactase gene on chromosome 2q21. FEBS Lett. 398:135-40
-
(1996)
FEBS Lett.
, vol.398
, pp. 135-140
-
-
Harvey, C.B.1
Wang, Y.2
Darmoul, D.3
Phillips, A.4
Mantei, N.5
-
27
-
-
0028815914
-
Studies on the expression of intestinal lactase in different individuals
-
Harvey CB, Wang Y, Hughes LA, Swallow DM, Thurrell WP, et al. 1995. Studies on the expression of intestinal lactase in different individuals. Gut 36:28-33
-
(1995)
Gut
, vol.36
, pp. 28-33
-
-
Harvey, C.B.1
Wang, Y.2
Hughes, L.A.3
Swallow, D.M.4
Thurrell, W.P.5
-
28
-
-
0019973492
-
Lactase polymorphism in adult British natives: Estimating allele frequencies by enzyme assays in autopsy samples
-
Ho MW, Povey S, Swallow D. 1982. Lactase polymorphism in adult British natives: estimating allele frequencies by enzyme assays in autopsy samples. Am. J. Hum. Genet. 34:650-57
-
(1982)
Am. J. Hum. Genet.
, vol.34
, pp. 650-657
-
-
Ho, M.W.1
Povey, S.2
Swallow, D.3
-
29
-
-
0031259976
-
Phylogenetic analysis of the evolution of lactose digestion in adults
-
Holden C, Mace R. 1997. Phylogenetic analysis of the evolution of lactose digestion in adults. Hum. Biol. 69:605-28
-
(1997)
Hum. Biol.
, vol.69
, pp. 605-628
-
-
Holden, C.1
Mace, R.2
-
30
-
-
0032722506
-
Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions
-
Hollox EJ, Poulter M, Wang Y, Krause A, Swallow DM. 1999. Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions. Eur. J. Hum. Genet. 7:791-800
-
(1999)
Eur. J. Hum. Genet.
, vol.7
, pp. 791-800
-
-
Hollox, E.J.1
Poulter, M.2
Wang, Y.3
Krause, A.4
Swallow, D.M.5
-
31
-
-
0035159157
-
Lactase haplotype diversity in the Old World
-
Hollox EJ, Poulter M, Zvarik M, Ferak V, Krause A, et al. 2001. Lactase haplotype diversity in the Old World. Am. J. Hum. Genet. 68:160-72
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 160-172
-
-
Hollox, E.J.1
Poulter, M.2
Zvarik, M.3
Ferak, V.4
Krause, A.5
-
32
-
-
0015256928
-
A simple screening method for lactose malabsorption
-
Isokoski M, Jussila J, Sarna S. 1972. A simple screening method for lactose malabsorption. Gastroenterology 62:28-32
-
(1972)
Gastroenterology
, vol.62
, pp. 28-32
-
-
Isokoski, M.1
Jussila, J.2
Sarna, S.3
-
33
-
-
0029155988
-
Folding of human intestinal lactase-phlorizin hydrolase
-
Jacob R, Bulleid NJ, Naim HY. 1995. Folding of human intestinal lactase-phlorizin hydrolase. J. Biol. Chem. 270:18678-84
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18678-18684
-
-
Jacob, R.1
Bulleid, N.J.2
Naim, H.Y.3
-
34
-
-
0037040930
-
The prosequence of human lactase-phlorizin hydrolase modulates the folding of the mature enzyme
-
Jacob R, Peters K, Naim HY. 2002. The prosequence of human lactase-phlorizin hydrolase modulates the folding of the mature enzyme. J. Biol. Chem. 277:8217-25
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8217-8225
-
-
Jacob, R.1
Peters, K.2
Naim, H.Y.3
-
35
-
-
1642586712
-
Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-phlorizin hydrolase gene
-
Jarvela I, Enattah NS, Kokkonen J, Varilo T, Savilahti E, et al. 1998. Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-phlorizin hydrolase gene. Am. J. Hum. Genet. 63:1078-85
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 1078-1085
-
-
Jarvela, I.1
Enattah, N.S.2
Kokkonen, J.3
Varilo, T.4
Savilahti, E.5
-
36
-
-
0028818924
-
Furin, PC1/3, and/or PC6A process rabbit, but not human, prolactase-phlorizin hydrolase to the 180-kDa intermediate
-
Keller P, Zecca L, Boukamel R, Zwicker E, Gloor S, et al. 1995. Furin, PC1/3, and/or PC6A process rabbit, but not human, prolactase-phlorizin hydrolase to the 180-kDa intermediate. J. Biol. Chem. 270:25722-28
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25722-25728
-
-
Keller, P.1
Zecca, L.2
Boukamel, R.3
Zwicker, E.4
Gloor, S.5
-
37
-
-
0014517863
-
Lactase deficiency in Thailand: Effect of prolonged lactose feeding
-
Keusch GT, Troncale FJ, Thavaramara B, Prinyanont P, Anderson PR, et al. 1969. Lactase deficiency in Thailand: effect of prolonged lactose feeding. Am. J. Clin. Nutr. 22:638-41
-
(1969)
Am. J. Clin. Nutr.
, vol.22
, pp. 638-641
-
-
Keusch, G.T.1
Troncale, F.J.2
Thavaramara, B.3
Prinyanont, P.4
Anderson, P.R.5
-
38
-
-
0030752589
-
Rat lactase-phlorizin hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice
-
Krasinski SD, Upchurch BH, Irons SJ, June RM, Mishra K, et al. 1997. Rat lactase-phlorizin hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice. Gastroenterology 113:844-55
-
(1997)
Gastroenterology
, vol.113
, pp. 844-855
-
-
Krasinski, S.D.1
Upchurch, B.H.2
Irons, S.J.3
June, R.M.4
Mishra, K.5
-
40
-
-
0038476614
-
Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia
-
Kuokkanen M, Enattah NS, Oksanen A, Savilahti E, Orpana A, et al. 2003. Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia. Gut 52:647-52
-
(2003)
Gut
, vol.52
, pp. 647-652
-
-
Kuokkanen, M.1
Enattah, N.S.2
Oksanen, A.3
Savilahti, E.4
Orpana, A.5
-
41
-
-
0037066758
-
Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter
-
Lee SY, Wang Z, Lin CK, Contag CH, Olds LC, et al. 2002. Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter. J. Biol. Chem. 277:13099-105
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13099-13105
-
-
Lee, S.Y.1
Wang, Z.2
Lin, C.K.3
Contag, C.H.4
Olds, L.C.5
-
42
-
-
0016839521
-
Recessive inheritance of the adult type of intestinal lactase deficiency
-
Lisker R, Gonzalez B, Daltabuit M. 1975. Recessive inheritance of the adult type of intestinal lactase deficiency. Am. J. Hum. Genet. 27:662-64
-
(1975)
Am. J. Hum. Genet.
, vol.27
, pp. 662-664
-
-
Lisker, R.1
Gonzalez, B.2
Daltabuit, M.3
-
43
-
-
0026555758
-
Regulation of intestinal lactase in adult hypolactasia
-
Lloyd M, Mevissen G, Fischer M, Olsen W, Goodspeed D, et al. 1992. Regulation of intestinal lactase in adult hypolactasia. J. Clin. Invest. 89:524-29
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 524-529
-
-
Lloyd, M.1
Mevissen, G.2
Fischer, M.3
Olsen, W.4
Goodspeed, D.5
-
44
-
-
0037178825
-
Enzymatic hydrolysis of pyridoxine-5′-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolase
-
Mackey AD, Henderson GN, Gregory JF 3rd. 2002. Enzymatic hydrolysis of pyridoxine-5′-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolase. J. Biol. Chem. 277:26858-64
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26858-26864
-
-
Mackey, A.D.1
Henderson, G.N.2
Gregory III, J.F.3
-
45
-
-
0026069545
-
Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia
-
Maiuri L, Raia V, Potter J, Swallow D, Ho MW, et al. 1991. Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia. Gastroenterology 100:359-69
-
(1991)
Gastroenterology
, vol.100
, pp. 359-369
-
-
Maiuri, L.1
Raia, V.2
Potter, J.3
Swallow, D.4
Ho, M.W.5
-
46
-
-
0028319212
-
Mosaic regulation of lactase in human adult-type hypolactasia
-
Maiuri L, Rossi M, Raia V, Garipoli V, Hughes LA, et al. 1994. Mosaic regulation of lactase in human adult-type hypolactasia. Gastroenterology 107:54-60
-
(1994)
Gastroenterology
, vol.107
, pp. 54-60
-
-
Maiuri, L.1
Rossi, M.2
Raia, V.3
Garipoli, V.4
Hughes, L.A.5
-
47
-
-
0024076253
-
Complete primary structure of human and rabbit lactase-phlorizin hydrolase: Implications for biosynthesis, membrane anchoring and evolution of the enzyme
-
Mantei N, Villa M, Enzler T, Wacker H, Boll W, et al. 1988. Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme. EMBO J. 7:2705-13
-
(1988)
EMBO J.
, vol.7
, pp. 2705-2713
-
-
Mantei, N.1
Villa, M.2
Enzler, T.3
Wacker, H.4
Boll, W.5
-
48
-
-
0033358667
-
Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to finescale genetic mapping
-
McPeek MS, Strahs A. 1999. Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to finescale genetic mapping. Am. J. Hum. Genet. 65:858-75
-
(1999)
Am. J. Hum. Genet.
, vol.65
, pp. 858-875
-
-
McPeek, M.S.1
Strahs, A.2
-
49
-
-
0032491591
-
Processing of human intestinal prolactase to an intermediate form by furin or by a furin-like proprotein convertase
-
Mesonero JE, Gloor SM, Semenza G. 1998. Processing of human intestinal prolactase to an intermediate form by furin or by a furin-like proprotein convertase. J. Biol. Chem. 273:29430-36
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29430-29436
-
-
Mesonero, J.E.1
Gloor, S.M.2
Semenza, G.3
-
51
-
-
0034163801
-
Interaction between the homeodomain proteins Cdx2 and HNF1 alpha mediates expression of the lactase-phlorizin hydrolase gene
-
Mitchelmore C, Troelsen JT, Spodsberg N, Sjostrom H, Noren O. 2000. Interaction between the homeodomain proteins Cdx2 and HNF1 alpha mediates expression of the lactase-phlorizin hydrolase gene. Biochem. J. 346(Part 2):529-35
-
(2000)
Biochem. J.
, vol.346
, Issue.2 PART
, pp. 529-535
-
-
Mitchelmore, C.1
Troelsen, J.T.2
Spodsberg, N.3
Sjostrom, H.4
Noren, O.5
-
52
-
-
0025876183
-
Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase
-
Montgomery RK, Büller HA, Rings EHHM, Grand RJ. 1991. Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase. FASEB J. 5:2824-32
-
(1991)
FASEB J.
, vol.5
, pp. 2824-2832
-
-
Montgomery, R.K.1
Büller, H.A.2
Rings, E.H.H.M.3
Grand, R.J.4
-
53
-
-
0029281959
-
The pro-region of human intestinal lactase-phlorizin hydrolase is enzymatically inactive towards lactose
-
Naim HY. 1995. The pro-region of human intestinal lactase-phlorizin hydrolase is enzymatically inactive towards lactose. Biol. Chem. Hoppe-Seyler 376:255-58
-
(1995)
Biol. Chem. Hoppe-Seyler
, vol.376
, pp. 255-258
-
-
Naim, H.Y.1
-
54
-
-
0028148546
-
The pro region of human intestinal lactase-phlorizin hydrolase
-
Naim HY, Jacob R, Naim H, Sambrook JF, Gething MJ. 1994. The pro region of human intestinal lactase-phlorizin hydrolase. J. Biol. Chem. 269:26933-43
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26933-26943
-
-
Naim, H.Y.1
Jacob, R.2
Naim, H.3
Sambrook, J.F.4
Gething, M.J.5
-
55
-
-
0026491215
-
Impact of O-glycosylation on the function of human intestinal lactase-phlorizin hydrolase. Characterization of glycoforms varying in enzyme activity and localization of O-glycoside addition
-
Naim HY, Lentze MJ. 1992. Impact of O-glycosylation on the function of human intestinal lactase-phlorizin hydrolase. Characterization of glycoforms varying in enzyme activity and localization of O-glycoside addition. J. Biol. Chem. 267:25494-504
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25494-25504
-
-
Naim, H.Y.1
Lentze, M.J.2
-
56
-
-
0022511288
-
Genetic relationship of human populations and ethnic differences in relation to drugs and food
-
ed. W Kalow, HW Goedde, DP Agarwal, New York: Alan R Liss
-
Nei M, Saitou N. 1986. Genetic relationship of human populations and ethnic differences in relation to drugs and food. In Ethnic Differences in Reactions to Drugs and Other Xenobiotics, ed. W Kalow, HW Goedde, DP Agarwal, pp. 21-37. New York: Alan R Liss
-
(1986)
Ethnic Differences in Reactions to Drugs and Other Xenobiotics
, pp. 21-37
-
-
Nei, M.1
Saitou, N.2
-
57
-
-
0037219688
-
Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans
-
Nemeth K, Plumb GW, Berrin JG, Juge N, Jacob R, et al. 2003. Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. Eur. J. Nutr. 42:29-42
-
(2003)
Eur. J. Nutr.
, vol.42
, pp. 29-42
-
-
Nemeth, K.1
Plumb, G.W.2
Berrin, J.G.3
Juge, N.4
Jacob, R.5
-
58
-
-
0013963615
-
Distribution of disaccharidase activity in the small bowel of normal and lactase-deficient subjects
-
Newcomer A, McGill D. 1966. Distribution of disaccharidase activity in the small bowel of normal and lactase-deficient subjects. Gastroenterology 51:481-88
-
(1966)
Gastroenterology
, vol.51
, pp. 481-488
-
-
Newcomer, A.1
McGill, D.2
-
59
-
-
0027497114
-
The pro sequence of lactase-phlorizin hydrolase is required for the enzyme to reach the plasma membrane. An intramolecular chaperone?
-
Oberholzer T, Mantei N, Semenza G. 1993. The pro sequence of lactase-phlorizin hydrolase is required for the enzyme to reach the plasma membrane. An intramolecular chaperone? FEBS Lett. 333:127-31
-
(1993)
FEBS Lett.
, vol.333
, pp. 127-131
-
-
Oberholzer, T.1
Mantei, N.2
Semenza, G.3
-
60
-
-
0032549533
-
Routing and processing of lactasephlorizin hydrolase in transfected Caco-2 cells
-
Ouwendijk J, Peters WJ, van de Vorstenbosch RA, Ginsel LA, Naim HY, et al. 1998. Routing and processing of lactasephlorizin hydrolase in transfected Caco-2 cells. J. Biol. Chem. 273:6650-55
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6650-6655
-
-
Ouwendijk, J.1
Peters, W.J.2
Van De Vorstenbosch, R.A.3
Ginsel, L.A.4
Naim, H.Y.5
-
61
-
-
0031801662
-
Comparison of a portable breath hydrogen analyser (Micro H2) with a Quintron MicroLyzer in measuring lactose maldigestion, and the evaluation of a Micro H2 for diagnosing hypolactasia
-
Peuhkuri K, Poussa T, Korpela R. 1998. Comparison of a portable breath hydrogen analyser (Micro H2) with a Quintron MicroLyzer in measuring lactose maldigestion, and the evaluation of a Micro H2 for diagnosing hypolactasia. Scand. J. Clin. Lab. Invest. 58:217-24
-
(1998)
Scand. J. Clin. Lab. Invest.
, vol.58
, pp. 217-224
-
-
Peuhkuri, K.1
Poussa, T.2
Korpela, R.3
-
62
-
-
0344375110
-
The causal element for the lactase persistence/non-persistence polymorphism is located in a 1Mb region of linkage disequilibrium in Europeans
-
Poulter M, Hollox E, Harvey CB, Mulcare CM, Peuhkuri K, et al. 2003. The causal element for the lactase persistence/non-persistence polymorphism is located in a 1Mb region of linkage disequilibrium in Europeans. Ann. Hum. Genet. 67:298-311
-
(2003)
Ann. Hum. Genet.
, vol.67
, pp. 298-311
-
-
Poulter, M.1
Hollox, E.2
Harvey, C.B.3
Mulcare, C.M.4
Peuhkuri, K.5
-
63
-
-
25344474886
-
Über die Resorption und die fermentative Spaltung der Disaccharide im Dünndarm des ausgewachsenen Hundes
-
Röhmann F, Nagano J. 1903. Über die Resorption und die fermentative Spaltung der Disaccharide im Dünndarm des ausgewachsenen Hundes. Arch. Ges. Physiol. 95:533-605
-
(1903)
Arch. Ges. Physiol.
, vol.95
, pp. 533-605
-
-
Röhmann, F.1
Nagano, J.2
-
64
-
-
0030936284
-
Lactase persistence versus decline in human adults: Multifactorial events are involved in down-regulation after weaning
-
Rossi M, Maiuri L, Fusco MI, Salvati VM, Fuccio A, et al. 1997. Lactase persistence versus decline in human adults: Multifactorial events are involved in down-regulation after weaning. Gastroenterology 112:1506-14
-
(1997)
Gastroenterology
, vol.112
, pp. 1506-1514
-
-
Rossi, M.1
Maiuri, L.2
Fusco, M.I.3
Salvati, V.M.4
Fuccio, A.5
-
65
-
-
0346191779
-
-
Deleted in proof
-
Deleted in proof
-
-
-
-
66
-
-
0016200992
-
The inheritance of selective adult-type lactose malabsorption
-
Sahi T. 1974. The inheritance of selective adult-type lactose malabsorption. Scand. J. Gastroenterol. 9:1-73
-
(1974)
Scand. J. Gastroenterol.
, vol.9
, pp. 1-73
-
-
Sahi, T.1
-
67
-
-
0020565593
-
Hypolactasia in a fixed cohort of young Finnish adults, a follow-up study
-
Sahi T, Launiala K, Laitinen H. 1983. Hypolactasia in a fixed cohort of young Finnish adults, a follow-up study. Scand. J. Gastroenterol. 18:865-70
-
(1983)
Scand. J. Gastroenterol.
, vol.18
, pp. 865-870
-
-
Sahi, T.1
Launiala, K.2
Laitinen, H.3
-
68
-
-
0020534236
-
Congenital lactase deficiency. A clinical study on 16 patients
-
Savilahti E, Launiala K, Kuitunen P. 1983. Congenital lactase deficiency. A clinical study on 16 patients. Arch. Dis. Child. 58:246-52
-
(1983)
Arch. Dis. Child.
, vol.58
, pp. 246-252
-
-
Savilahti, E.1
Launiala, K.2
Kuitunen, P.3
-
69
-
-
0024421045
-
Control of lactase in human adult-type hypolactasia and in weaning rabbits and rats
-
Sebastio G, Villa M, Sartorio R, Guzzetta V, Poggi V et al. 1989. Control of lactase in human adult-type hypolactasia and in weaning rabbits and rats. Am. J. Hum. Genet. 45:489-97
-
(1989)
Am. J. Hum. Genet.
, vol.45
, pp. 489-497
-
-
Sebastio, G.1
Villa, M.2
Sartorio, R.3
Guzzetta, V.4
Poggi, V.5
-
70
-
-
0034038294
-
Possible connection between milk and coronary heart disease: The calcium hypothesis
-
Seely S. 2000. Possible connection between milk and coronary heart disease: the calcium hypothesis. Med. Hypotheses 54:701-3
-
(2000)
Med. Hypotheses
, vol.54
, pp. 701-703
-
-
Seely, S.1
-
71
-
-
0019073964
-
Age of onset of lactose malabsorption
-
Simoons F. 1980. Age of onset of lactose malabsorption. Pediatrics 66:646-48
-
(1980)
Pediatrics
, vol.66
, pp. 646-648
-
-
Simoons, F.1
-
72
-
-
0034089033
-
Balancing selection at closely linked, overdominant loci in a finite population
-
Slatkin M. 2000. Balancing selection at closely linked, overdominant loci in a finite population. Genetics 154:1367-78
-
(2000)
Genetics
, vol.154
, pp. 1367-1378
-
-
Slatkin, M.1
-
73
-
-
0034976976
-
The use of intraallelic variability for testing neutrality and estimating population growth rate
-
Slatkin M, Bertorelle G. 2001. The use of intraallelic variability for testing neutrality and estimating population growth rate. Genetics 158:865-74
-
(2001)
Genetics
, vol.158
, pp. 865-874
-
-
Slatkin, M.1
Bertorelle, G.2
-
74
-
-
0032999058
-
Transcriptional regulation of pig lactasephlorizin hydrolase: Involvement of HNF-1 and FREACs
-
Spodsberg N, Troelsen JT, Carlsson P, Enerback S, Sjostrom H, et al. 1999. Transcriptional regulation of pig lactasephlorizin hydrolase: involvement of HNF-1 and FREACs. Gastroenterology 116:842-54
-
(1999)
Gastroenterology
, vol.116
, pp. 842-854
-
-
Spodsberg, N.1
Troelsen, J.T.2
Carlsson, P.3
Enerback, S.4
Sjostrom, H.5
-
75
-
-
0025066272
-
Biogenesis of intestinal lactase-phlorizin hydrolase in adults with lactose intolerance. Evidence for reduced biosynthesis and slowed-down maturation in enterocytes
-
Sterchi E, Mills P, Fransen J, Hauri H, Lentze M, et al. 1990. Biogenesis of intestinal lactase-phlorizin hydrolase in adults with lactose intolerance. Evidence for reduced biosynthesis and slowed-down maturation in enterocytes. J. Clin. Invest. 86:1329-37
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 1329-1337
-
-
Sterchi, E.1
Mills, P.2
Fransen, J.3
Hauri, H.4
Lentze, M.5
-
76
-
-
0005264308
-
The genetic polymorphism of intestinal lactose activity in adult humans
-
ed. CR Scriver, AL Beaudet, WS Sly, D Valle, New York: McGraw-Hill
-
Swallow DM, Hollox EJ. 2000. The genetic polymorphism of intestinal lactose activity in adult humans. In The Metabolic and Molecular Basis of Inherited Disease, ed. CR Scriver, AL Beaudet, WS Sly, D Valle, pp. 1651-62. New York: McGraw-Hill
-
(2000)
The Metabolic and Molecular Basis of Inherited Disease
, pp. 1651-1662
-
-
Swallow, D.M.1
Hollox, E.J.2
-
77
-
-
0025353609
-
Age dependency of the lactase persistence and lactase restriction phenotypes among children in Sri Lanka and Britain
-
Thomas S, Walker-Smith JA, Senewiratne B, Hjelm M. 1990. Age dependency of the lactase persistence and lactase restriction phenotypes among children in Sri Lanka and Britain. J. Trop. Pediatr. 36:80-85
-
(1990)
J. Trop. Pediatr.
, vol.36
, pp. 80-85
-
-
Thomas, S.1
Walker-Smith, J.A.2
Senewiratne, B.3
Hjelm, M.4
-
78
-
-
0028350976
-
1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice
-
Troelsen JT, Mehlum A, Olsen J, Spodsberg N, Hansen GH, et al. 1994. 1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice. FEES Lett. 342:291-96
-
(1994)
FEES Lett.
, vol.342
, pp. 291-296
-
-
Troelsen, J.T.1
Mehlum, A.2
Olsen, J.3
Spodsberg, N.4
Hansen, G.H.5
-
79
-
-
0037434625
-
An enhancer activates the pig lactase phlorizin hydrolase promoter in intestinal cells
-
Troelsen JT, Mitchelmore C, Olsen J. 2003. An enhancer activates the pig lactase phlorizin hydrolase promoter in intestinal cells. Gene 305:101-11
-
(2003)
Gene
, vol.305
, pp. 101-111
-
-
Troelsen, J.T.1
Mitchelmore, C.2
Olsen, J.3
-
80
-
-
0028354491
-
Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-somaltase promoters are functionally related oligomeric molecules
-
Troelsen JT, Olsen J, Mitchelmore C, Hansen GH, Sjostrom H, et al. 1994. Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-somaltase promoters are functionally related oligomeric molecules. FEBS Lett. 342:297-301
-
(1994)
FEBS Lett.
, vol.342
, pp. 297-301
-
-
Troelsen, J.T.1
Olsen, J.2
Mitchelmore, C.3
Hansen, G.H.4
Sjostrom, H.5
-
81
-
-
0037008768
-
Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter
-
van Wering HM, Huibregtse IL, van der Zwan SM, de Bie MS, Dowling LN, et al. 2002. Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter. J. Biol. Chem, 277:27659-67
-
(2002)
J. Biol. Chem
, vol.277
, pp. 27659-27667
-
-
Van Wering, H.M.1
Huibregtse, I.L.2
Van Der Zwan, S.M.3
De Bie, M.S.4
Dowling, L.N.5
-
84
-
-
0028111954
-
Expression of human intestinal mRNA transcripts during development: Analysis by a semiquantitative RNA polymerase chain reaction method
-
Wang Y, Harvey C, Rousset M, Swallow DM. 1994. Expression of human intestinal mRNA transcripts during development: analysis by a semiquantitative RNA polymerase chain reaction method. Pediatr. Res. 36:514-21
-
(1994)
Pediatr. Res.
, vol.36
, pp. 514-521
-
-
Wang, Y.1
Harvey, C.2
Rousset, M.3
Swallow, D.M.4
-
85
-
-
0031750479
-
The genetically programmed down-regulation of lactase in children
-
Wang Y, Harvey CB, Hollox EJ, Phillips AD, Poulter M, et al. 1998. The genetically programmed down-regulation of lactase in children. Gastroenterology 114:1230-36
-
(1998)
Gastroenterology
, vol.114
, pp. 1230-1236
-
-
Wang, Y.1
Harvey, C.B.2
Hollox, E.J.3
Phillips, A.D.4
Poulter, M.5
-
86
-
-
0028969249
-
The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element
-
Wang Y, Harvey CB, Pratt WS, Sams VR, Sarner M, et al. 1995. The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element. Hum. Mol. Genet. 4:657-62
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 657-662
-
-
Wang, Y.1
Harvey, C.B.2
Pratt, W.S.3
Sams, V.R.4
Sarner, M.5
-
87
-
-
0032478305
-
Evolutionary matches of enzyme and transporter capacities to dietary substrate loads in the intestinal brush border
-
Weiss SL, Lee EA, Diamond J. 1998. Evolutionary matches of enzyme and transporter capacities to dietary substrate loads in the intestinal brush border. Proc. Natl. Acad. Sci. USA 95:2117-21
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2117-2121
-
-
Weiss, S.L.1
Lee, E.A.2
Diamond, J.3
-
88
-
-
0025053826
-
The biosynthetic basis of adult lactase deficiency
-
Witte J, Lloyd M, Lorenzsonn V, Korsmo H, Olsen W 1990. The biosynthetic basis of adult lactase deficiency. J. Clin. Invest. 86:1338-42
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 1338-1342
-
-
Witte, J.1
Lloyd, M.2
Lorenzsonn, V.3
Korsmo, H.4
Olsen, W.5
-
89
-
-
0025711634
-
Lactose maldigestion - Age specific prevalence in black and Indian children
-
Wittenberg D, Moosa A. 1990. Lactose maldigestion - age specific prevalence in black and Indian children. S. Afr. Med. J. 78:470-72
-
(1990)
S. Afr. Med. J.
, vol.78
, pp. 470-472
-
-
Wittenberg, D.1
Moosa, A.2
-
90
-
-
0032725550
-
Species differences in the sites of cleavage of pro-lactase to lactase supports lack of selective pressure
-
Zecca L, Mesonero JE, Gloor SM, Semenza G. 1999. Species differences in the sites of cleavage of pro-lactase to lactase supports lack of selective pressure. Biochim. Biophys. Acta 1435:51-60
-
(1999)
Biochim. Biophys. Acta
, vol.1435
, pp. 51-60
-
-
Zecca, L.1
Mesonero, J.E.2
Gloor, S.M.3
Semenza, G.4
-
91
-
-
0032544605
-
Intestinal lactasephlorizin hydrolase (LPH): The two catalytic sites; the role of the pancreas in pro-LPH maturation
-
Zecca L, Mesonero JE, Stutz A, Poiree JC, Giudicelli J, et al. 1998. Intestinal lactasephlorizin hydrolase (LPH): the two catalytic sites; the role of the pancreas in pro-LPH maturation. FEBS Lett. 435:225-28
-
(1998)
FEBS Lett.
, vol.435
, pp. 225-228
-
-
Zecca, L.1
Mesonero, J.E.2
Stutz, A.3
Poiree, J.C.4
Giudicelli, J.5
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