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Volumn 19, Issue 11, 2002, Pages 1991-2004

Abundant raw material for cis-regulatory evolution in humans

Author keywords

Evolution of development; Gene network; Gene regulation; Polymorphism; Promoter; Transcription

Indexed keywords

DNA; TRANSCRIPTION FACTOR; MICROSATELLITE DNA;

EID: 0036855185     PISSN: 07374038     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.molbev.a004023     Document Type: Article
Times cited : (317)

References (91)
  • 1
    • 0032881999 scopus 로고    scopus 로고
    • Transcriptional regulation of the human type I collagen α2 (COL1A2) gene by the combination of two dinucleotide repeats
    • Akai, J., A. Kimura, and R. I. Hata. 1999. Transcriptional regulation of the human type I collagen α2 (COL1A2) gene by the combination of two dinucleotide repeats. Gene 239:65-73.
    • (1999) Gene , vol.239 , pp. 65-73
    • Akai, J.1    Kimura, A.2    Hata, R.I.3
  • 2
    • 0033797241 scopus 로고    scopus 로고
    • A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
    • Baier, L. J., P. A. Permana, X. Yang et al. (13 co-authors). 2000. A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J. Clin. Investig. 106:R69-R73.
    • (2000) J. Clin. Investig. , vol.106
    • Baier, L.J.1    Permana, P.A.2    Yang, X.3
  • 3
    • 0032742405 scopus 로고    scopus 로고
    • Allelic variation in transcription modulates MHC class II expression and function
    • Beaty, J. S., T. L. Sukiennicki, and G. T. NEPOM. 1999. Allelic variation in transcription modulates MHC class II expression and function. Microbes Infect. 1:919-927.
    • (1999) Microbes Infect. , vol.1 , pp. 919-927
    • Beaty, J.S.1    Sukiennicki, T.L.2    Nepom, G.T.3
  • 4
    • 0032493441 scopus 로고    scopus 로고
    • Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
    • Beutler, E., T. Gelbart, and A. Demina. 1998. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism? Proc. Natl. Acad. Sci. USA 95:8170-8174.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8170-8174
    • Beutler, E.1    Gelbart, T.2    Demina, A.3
  • 5
    • 0035864637 scopus 로고    scopus 로고
    • Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor
    • Botma, G. J., A. J. Verhoeven, and H. Jansen. 2001. Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor. Atherosclerosis 154:625-632.
    • (2001) Atherosclerosis , vol.154 , pp. 625-632
    • Botma, G.J.1    Verhoeven, A.J.2    Jansen, H.3
  • 7
    • 0037177625 scopus 로고    scopus 로고
    • Genetic dissection of transcriptional regulation in budding yeast
    • Brem, R. B., G. Yvert, R. Clinton, and L. Kruglyak. 2002. Genetic dissection of transcriptional regulation in budding yeast. Science 296:752-755.
    • (2002) Science , vol.296 , pp. 752-755
    • Brem, R.B.1    Yvert, G.2    Clinton, R.3    Kruglyak, L.4
  • 8
    • 0031593249 scopus 로고    scopus 로고
    • Mobile elements inserted in the distant past have taken on important functions
    • Britten, R. J. 1997. Mobile elements inserted in the distant past have taken on important functions. Gene 205:177-182.
    • (1997) Gene , vol.205 , pp. 177-182
    • Britten, R.J.1
  • 9
    • 0014690698 scopus 로고
    • Gene regulation for higher cells: A theory
    • Britten, R. J., and E. H. Davidson. 1969. Gene regulation for higher cells: A theory. Science 165:349-357.
    • (1969) Science , vol.165 , pp. 349-357
    • Britten, R.J.1    Davidson, E.H.2
  • 10
    • 0033289533 scopus 로고    scopus 로고
    • Genomes were forged by massive bombardments with retroelements and retrosequences
    • Brosius, J. 1999. Genomes were forged by massive bombardments with retroelements and retrosequences. Genetica 107:209-238.
    • (1999) Genetica , vol.107 , pp. 209-238
    • Brosius, J.1
  • 11
    • 0033358728 scopus 로고    scopus 로고
    • Sequence diversity in 36 candidate genes for cardiovascular disorders
    • Cambien, F., O. Poirier, V. Nicaud et al. (16 co-authors). 1999. Sequence diversity in 36 candidate genes for cardiovascular disorders. Am. J. Hum. Genet. 65:183-191.
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 183-191
    • Cambien, F.1    Poirier, O.2    Nicaud, V.3
  • 13
    • 0032991552 scopus 로고    scopus 로고
    • Characterization of single-nucleotide polymorphisms in coding regions of human genes
    • Cargill, M., D. Altshuler, J. Ireland et al. (18 co-authors). 1999. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat. Genet. 22:231-238.
    • (1999) Nat. Genet. , vol.22 , pp. 231-238
    • Cargill, M.1    Altshuler, D.2    Ireland, J.3
  • 15
    • 0034710896 scopus 로고    scopus 로고
    • Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis
    • Cavalieri, D., J. P. Townsend, and D. L. Hartl. 2000. Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis. Proc. Natl. Acad. Sci. USA 97:12369-12374.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12369-12374
    • Cavalieri, D.1    Townsend, J.P.2    Hartl, D.L.3
  • 16
    • 0033945005 scopus 로고    scopus 로고
    • Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction
    • Corbex, M., O. Poirier, F. Fumeron, D. Betoulle, A. Evans, J. B. Ruidavets, D. Arveiler, G. Luc, L. Tiret, and F. Cambien. 2000. Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction. Genet. Epidemiol. 19:64-80.
    • (2000) Genet. Epidemiol. , vol.19 , pp. 64-80
    • Corbex, M.1    Poirier, O.2    Fumeron, F.3    Betoulle, D.4    Evans, A.5    Ruidavets, J.B.6    Arveiler, D.7    Luc, G.8    Tiret, L.9    Cambien, F.10
  • 17
    • 0033034855 scopus 로고    scopus 로고
    • Evolutionary analysis of TATA-less proximal promoter function
    • Crawford, D. L., J. A. Segal, and J. L. Barnett. 1999. Evolutionary analysis of TATA-less proximal promoter function. Mol. Biol. Evol. 16:194-207.
    • (1999) Mol. Biol. Evol. , vol.16 , pp. 194-207
    • Crawford, D.L.1    Segal, J.A.2    Barnett, J.L.3
  • 18
    • 0028285005 scopus 로고
    • Quantitative trait loci underlying gene product variation: A novel perspective for analyzing regulation of genome expression
    • Damerval, C., A. Maurice, J. M. Josse, and D. De Vienne. 1994. Quantitative trait loci underlying gene product variation: A novel perspective for analyzing regulation of genome expression. Genetics 137:289-301.
    • (1994) Genetics , vol.137 , pp. 289-301
    • Damerval, C.1    Maurice, A.2    Josse, J.M.3    De Vienne, D.4
  • 22
    • 13344259999 scopus 로고    scopus 로고
    • A comprehensive genetic map of the human genome based on 5,264 microsatellites
    • Dib, C., S. Faure, C. Fizames et al. (14 co-authors). 1996. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380:152-154.
    • (1996) Nature , vol.380 , pp. 152-154
    • Dib, C.1    Faure, S.2    Fizames, C.3
  • 24
    • 0037066542 scopus 로고    scopus 로고
    • Intra- and interspecific variation in primate gene expression patterns
    • Enard, W., P. Khaitovich, J. Klose et al. (13 co-authors). 2002. Intra- and interspecific variation in primate gene expression patterns. Science 296:340-343.
    • (2002) Science , vol.296 , pp. 340-343
    • Enard, W.1    Khaitovich, P.2    Klose, J.3
  • 25
    • 0030600144 scopus 로고    scopus 로고
    • Genomic simple repetitive DNAs are targets for differential binding of nuclear proteins
    • Epplen, J. T., A. Kyas, and W. Maueler. 1996. Genomic simple repetitive DNAs are targets for differential binding of nuclear proteins. FEBS Lett. 389:92-95.
    • (1996) FEBS Lett. , vol.389 , pp. 92-95
    • Epplen, J.T.1    Kyas, A.2    Maueler, W.3
  • 26
    • 0035980092 scopus 로고    scopus 로고
    • A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels
    • Farzaneh-Far, A., J. D. Davies, L. A. Braam, H. M. Spronk, D. Proudfoot, S. W. Chan, K. M. O'Shaughnessy, P. L. Weissberg, C. Vermeer, and C. M. Shanahan. 2001. A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. J. Biol. Chem. 276:32466-32473.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32466-32473
    • Farzaneh-Far, A.1    Davies, J.D.2    Braam, L.A.3    Spronk, H.M.4    Proudfoot, D.5    Chan, S.W.6    O'Shaughnessy, K.M.7    Weissberg, P.L.8    Vermeer, C.9    Shanahan, C.M.10
  • 28
    • 0034810974 scopus 로고    scopus 로고
    • Nonlinear developmental processes as sources of dominance
    • Gilchrist, M. A., and H. F. Nijhout. 2001. Nonlinear developmental processes as sources of dominance. Genetics 159:423-432.
    • (2001) Genetics , vol.159 , pp. 423-432
    • Gilchrist, M.A.1    Nijhout, H.F.2
  • 29
    • 0034966656 scopus 로고    scopus 로고
    • Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus
    • Gong, Q. H., J. W. Cho, T. Huang et al. (11 co-authors). 2001. Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. Pharmacogenetics 11:357-368.
    • (2001) Pharmacogenetics , vol.11 , pp. 357-368
    • Gong, Q.H.1    Cho, J.W.2    Huang, T.3
  • 30
    • 13044263875 scopus 로고    scopus 로고
    • Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes
    • Gonzalez, E., M. Bamshad, N. Sato et al. (22 co-authors). 1999. Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proc. Natl. Acad. Sci. USA 96:12004-12009.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12004-12009
    • Gonzalez, E.1    Bamshad, M.2    Sato, N.3
  • 31
    • 19244384846 scopus 로고    scopus 로고
    • Global survey of genetic variation in CCR5, RANTES, and MIP-1α: Impact on the epidemiology of the HIV-1 pandemic
    • Gonzalez, E., R. Dhanda, M. Bamshad et al. (16 co-authors). 2001. Global survey of genetic variation in CCR5, RANTES, and MIP-1α: Impact on the epidemiology of the HIV-1 pandemic. Proc. Natl. Acad. Sci. USA 98:5199-5204.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5199-5204
    • Gonzalez, E.1    Dhanda, R.2    Bamshad, M.3
  • 35
    • 0021707651 scopus 로고
    • Enhanced gene expression by the poly(dT-dG)·poly(dC-dA) sequence
    • Hamada, H., M. Seidman, B. H. Howard, and C. M. Gorman. 1984. Enhanced gene expression by the poly(dT-dG)·poly(dC-dA) sequence. Mol. Cell. Biol. 4:2622-2630.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 2622-2630
    • Hamada, H.1    Seidman, M.2    Howard, B.H.3    Gorman, C.M.4
  • 36
    • 0033911892 scopus 로고    scopus 로고
    • Detection of the signature of natural selection in humans: Evidence from the Duffy blood group locus
    • Hamblin, M. T., and A. Di Rienzo. 2000. Detection of the signature of natural selection in humans: Evidence from the Duffy blood group locus. Am. J. Hum. Genet. 66:1669-1679.
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 1669-1679
    • Hamblin, M.T.1    Di Rienzo, A.2
  • 38
    • 0030893575 scopus 로고    scopus 로고
    • A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
    • Inoue, I., T. Nakajima, C. S. Williams et al. (12 co-authors). 1997. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J. Clin. Investig. 99:1786-1797.
    • (1997) J. Clin. Investig. , vol.99 , pp. 1786-1797
    • Inoue, I.1    Nakajima, T.2    Williams, C.S.3
  • 39
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium. 2001. Initial sequencing and analysis of the human genome. Nature 409:860-921.
    • (2001) Nature , vol.409 , pp. 860-921
  • 40
    • 0032903908 scopus 로고    scopus 로고
    • The transcriptional program in the response of human fibroblasts to serum
    • Iyer, V. R., M. B. Eisen, D. T. Ross et al. (14 co-authors). 1999. The transcriptional program in the response of human fibroblasts to serum. Science 283:83-87.
    • (1999) Science , vol.283 , pp. 83-87
    • Iyer, V.R.1    Eisen, M.B.2    Ross, D.T.3
  • 41
    • 0033856076 scopus 로고    scopus 로고
    • Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients
    • James, R. W., I. Leviev, J. Ruiz, P. Passa, P. Froguel, and M. C. Garin. 2000. Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients. Diabetes 49:1390-1393.
    • (2000) Diabetes , vol.49 , pp. 1390-1393
    • James, R.W.1    Leviev, I.2    Ruiz, J.3    Passa, P.4    Froguel, P.5    Garin, M.C.6
  • 42
    • 0034946468 scopus 로고    scopus 로고
    • Interaction of the common apolipoprotein C-III (APOC3-482C > T) and hepatic lipase (LIPC-514C > T) promoter variants affects glucose tolerance in young adults
    • Jansen, H., D. M. Waterworth, V. Nicaud, C. Ehnholm, and P. J. Talmud. 2001. Interaction of the common apolipoprotein C-III (APOC3-482C > T) and hepatic lipase (LIPC-514C > T) promoter variants affects glucose tolerance in young adults. Ann. Hum. Genet. 65:237-243.
    • (2001) Ann. Hum. Genet. , vol.65 , pp. 237-243
    • Jansen, H.1    Waterworth, D.M.2    Nicaud, V.3    Ehnholm, C.4    Talmud, P.J.5
  • 43
    • 0035733752 scopus 로고    scopus 로고
    • The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster
    • Jin, W., R. M. Riley, R. D. Wolfinger, K. P. White, G. Pas-Sador-Gurgel, and G. Gibson. 2001. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Nat. Genet. 29:389-395.
    • (2001) Nat. Genet. , vol.29 , pp. 389-395
    • Jin, W.1    Riley, R.M.2    Wolfinger, R.D.3    White, K.P.4    Pas-Sador-Gurgel, G.5    Gibson, G.6
  • 44
    • 0031081111 scopus 로고    scopus 로고
    • Simple sequence repeats as a source of quantitative genetic variation
    • Kashi, Y., D. King, and M. Soller. 1997. Simple sequence repeats as a source of quantitative genetic variation. Trends Genet. 13:74-78.
    • (1997) Trends Genet. , vol.13 , pp. 74-78
    • Kashi, Y.1    King, D.2    Soller, M.3
  • 45
    • 0028881617 scopus 로고
    • The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription
    • Kennedy, G. C., M. S. German, and W. J. Rutter. 1995. The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. Nat. Genet. 9:293-298.
    • (1995) Nat. Genet. , vol.9 , pp. 293-298
    • Kennedy, G.C.1    German, M.S.2    Rutter, W.J.3
  • 46
    • 0016669094 scopus 로고
    • Evolution at two levels in humans and chimpanzees
    • King, M. C., and A. C. Wilson. 1975. Evolution at two levels in humans and chimpanzees. Science 188:107-116.
    • (1975) Science , vol.188 , pp. 107-116
    • King, M.C.1    Wilson, A.C.2
  • 49
    • 0035889904 scopus 로고    scopus 로고
    • A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity
    • Levan, T D., J. W. Bloom, T. J. Bailey, C. L. Karp, M. Halonen, F. D. Martinez, and D. Vercelli. 2001. A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity. J. Immunol. 167:5838-5844.
    • (2001) J. Immunol. , vol.167 , pp. 5838-5844
    • Levan, T.D.1    Bloom, J.W.2    Bailey, T.J.3    Karp, C.L.4    Halonen, M.5    Martinez, F.D.6    Vercelli, D.7
  • 50
    • 0000244010 scopus 로고
    • The apportionment of human diversity
    • Lewontin, R. C. 1972. The apportionment of human diversity. Evol. Biol. 6:381-398.
    • (1972) Evol. Biol. , vol.6 , pp. 381-398
    • Lewontin, R.C.1
  • 52
    • 0028881810 scopus 로고
    • Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia
    • Li, W. W., M. M. Dammerman, J. D. Smith, S. Metzger, J. L. Breslow, and T. Leff. 1995. Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. J. Clin. Investig. 96:2601-2605.
    • (1995) J. Clin. Investig. , vol.96 , pp. 2601-2605
    • Li, W.W.1    Dammerman, M.M.2    Smith, J.D.3    Metzger, S.4    Breslow, J.L.5    Leff, T.6
  • 53
    • 0026053092 scopus 로고
    • Low nucleotide diversity in man
    • Li, W.-H., and L. A. Sadler. 1991. Low nucleotide diversity in man. Genetics 129:513-523.
    • (1991) Genetics , vol.129 , pp. 513-523
    • Li, W.-H.1    Sadler, L.A.2
  • 54
    • 0031803646 scopus 로고    scopus 로고
    • Weighing in on diabetes risk
    • McCarthy, M. 1998. Weighing in on diabetes risk. Nat. Genet. 19:209-210.
    • (1998) Nat. Genet. , vol.19 , pp. 209-210
    • McCarthy, M.1
  • 55
    • 0035038370 scopus 로고    scopus 로고
    • Influence of an inducible nitric oxide synthase promoter variant on clinical variables in patients with coronary artery disease
    • Morris, B. J., C. L. Glenn, D. E. Wilcken, and X. L. Wang. 2001. Influence of an inducible nitric oxide synthase promoter variant on clinical variables in patients with coronary artery disease. Clin. Sci. (Lond.) 100:551-556.
    • (2001) Clin. Sci. (Lond.) , vol.100 , pp. 551-556
    • Morris, B.J.1    Glenn, C.L.2    Wilcken, D.E.3    Wang, X.L.4
  • 56
    • 0033828761 scopus 로고    scopus 로고
    • Estimate of the mutation rate per nucleotide in humans
    • Nachman, M. W., and S. L. Crowell. 2000. Estimate of the mutation rate per nucleotide in humans. Genetics 156:297-304.
    • (2000) Genetics , vol.156 , pp. 297-304
    • Nachman, M.W.1    Crowell, S.L.2
  • 57
    • 0030964911 scopus 로고    scopus 로고
    • Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene
    • Naganawa, S., H. N. Ginsberg, R. M. Glickman, and G. S. Ginsburg. 1997. Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene. J. Clin. Investig. 99:1958-1965.
    • (1997) J. Clin. Investig. , vol.99 , pp. 1958-1965
    • Naganawa, S.1    Ginsberg, H.N.2    Glickman, R.M.3    Ginsburg, G.S.4
  • 58
    • 0025276590 scopus 로고
    • n sequences upstream of the rat prolactin gene form Z-DNA and inhibit gene transcription
    • n sequences upstream of the rat prolactin gene form Z-DNA and inhibit gene transcription. Nucleic Acids Res. 18:1595-1601.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1595-1601
    • Naylor, L.H.1    Clark, E.M.2
  • 59
    • 70349566593 scopus 로고
    • Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
    • Neel, J. V. 1962. Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"? Am. J. Hum. Genet. 14:353-362.
    • (1962) Am. J. Hum. Genet. , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 60
    • 0000758067 scopus 로고    scopus 로고
    • Developmental models and polygenic characters
    • Nijhout, H. F., and S. M. Paulsen. 1997. Developmental models and polygenic characters. Am. Nat. 149:394-405.
    • (1997) Am. Nat. , vol.149 , pp. 394-405
    • Nijhout, H.F.1    Paulsen, S.M.2
  • 61
    • 0032486384 scopus 로고    scopus 로고
    • The INS 5′ variable number of tandem repeats is associated with IGF2 expression in humans
    • Paquette, J., N. Giannoukakis, C. Polychronakos, P. VafIadis, and C. Deal. 1998. The INS 5′ variable number of tandem repeats is associated with IGF2 expression in humans. J. Biol. Chem. 273:14158-14164.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14158-14164
    • Paquette, J.1    Giannoukakis, N.2    Polychronakos, C.3    VafIadis, P.4    Deal, C.5
  • 62
    • 18244421874 scopus 로고    scopus 로고
    • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
    • Pugliese, A., M. Zeller, A. Fernandez Jr., L. J. Zalcberg, R. J. Bartlett, C. Ricordi, M. Pietropaolo, G. S. Ei-Senbarth, S. T. Bennett, and D. D. Patel. 1997. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat. Genet. 15:293-297.
    • (1997) Nat. Genet. , vol.15 , pp. 293-297
    • Pugliese, A.1    Zeller, M.2    Fernandez A., Jr.3    Zalcberg, L.J.4    Bartlett, R.J.5    Ricordi, C.6    Pietropaolo, M.7    Ei-Senbarth, G.S.8    Bennett, S.T.9    Patel, D.D.10
  • 63
    • 0035979178 scopus 로고    scopus 로고
    • A polymorphic dinucleotide repeat in the rat nucleolin gene forms Z-DNA and inhibits promoter activity
    • Rothenburg, S., F. Koch-nolte, A. Rich, and F. Haag. 2001. A polymorphic dinucleotide repeat in the rat nucleolin gene forms Z-DNA and inhibits promoter activity. Proc. Natl. Acad. Sci. USA 98:8985-8990.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8985-8990
    • Rothenburg, S.1    Koch-nolte, F.2    Rich, A.3    Haag, F.4
  • 64
    • 0032404174 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription
    • Rutter, J. L., T. I. Mitchell, G. Buttice, J. Meyers, J. F. Gusella, L. J. Ozelius, and C. E. Brinckerhoff. 1998. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription. Cancer Res. 58:5321-5325.
    • (1998) Cancer Res. , vol.58 , pp. 5321-5325
    • Rutter, J.L.1    Mitchell, T.I.2    Buttice, G.3    Meyers, J.4    Gusella, J.F.5    Ozelius, L.J.6    Brinckerhoff, C.E.7
  • 65
    • 0035978759 scopus 로고    scopus 로고
    • Natural selection and resistance to HIV
    • Schliekelman, P., C. Garner, and M. Slatkin. 2001. Natural selection and resistance to HIV. Nature 411:545-546.
    • (2001) Nature , vol.411 , pp. 545-546
    • Schliekelman, P.1    Garner, C.2    Slatkin, M.3
  • 66
    • 0026752148 scopus 로고
    • Mapping Z-DNA in the human genome. Computer-aided mapping reveals a nonrandom distribution of potential Z-DNA-forming sequences in human genes
    • Schroth, G. P., P. J. Chou, and P. S. Ho. 1992. Mapping Z-DNA in the human genome. Computer-aided mapping reveals a nonrandom distribution of potential Z-DNA-forming sequences in human genes. J. Biol. Chem. 267:11846-11855.
    • (1992) J. Biol. Chem. , vol.267 , pp. 11846-11855
    • Schroth, G.P.1    Chou, P.J.2    Ho, P.S.3
  • 67
    • 0034612332 scopus 로고    scopus 로고
    • Adaptive variation in lactate dehydrogenase-B gene expression: Role of a stress-responsive regulatory element
    • Schulte, P. M., H. C. Glemet, A. A. Fiebig, and D. A. Powers. 2000. Adaptive variation in lactate dehydrogenase-B gene expression: Role of a stress-responsive regulatory element. Proc. Natl. Acad. Sci. USA 97:6597-6602.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6597-6602
    • Schulte, P.M.1    Glemet, H.C.2    Fiebig, A.A.3    Powers, D.A.4
  • 68
    • 0032935301 scopus 로고    scopus 로고
    • Evidence for a functional repeat polymorphism in the promoter of the human NRAMP1 gene that correlates with autoimmune versus infectious disease susceptibility
    • Searle, S., and J. M. Blackwell. 1999. Evidence for a functional repeat polymorphism in the promoter of the human NRAMP1 gene that correlates with autoimmune versus infectious disease susceptibility. J. Med. Genet. 36:295-299.
    • (1999) J. Med. Genet. , vol.36 , pp. 295-299
    • Searle, S.1    Blackwell, J.M.2
  • 72
    • 0030453209 scopus 로고    scopus 로고
    • Molecular dissection of a major gene effect on a quantitative trait: The level of alcohol dehydrogenase expression in Drosophila melanogaster
    • Stam, L. F., and C. C. Laurie. 1996. Molecular dissection of a major gene effect on a quantitative trait: The level of alcohol dehydrogenase expression in Drosophila melanogaster. Genetics 144:1559-1564.
    • (1996) Genetics , vol.144 , pp. 1559-1564
    • Stam, L.F.1    Laurie, C.C.2
  • 73
    • 0035919656 scopus 로고    scopus 로고
    • Haplotype variation and linkage disequilibrium in 313 human genes
    • Stephens, J. C., J. A. Schneider, D. A. Tanguay et al. (28 co-authors). 2001. Haplotype variation and linkage disequilibrium in 313 human genes. Science 293:489-493.
    • (2001) Science , vol.293 , pp. 489-493
    • Stephens, J.C.1    Schneider, J.A.2    Tanguay, D.A.3
  • 74
    • 0034251814 scopus 로고    scopus 로고
    • Evolutionary developmental biology and the problem of variation
    • Stern, D. L. 2000. Evolutionary developmental biology and the problem of variation. Evolution 54:1079-1091.
    • (2000) Evolution , vol.54 , pp. 1079-1091
    • Stern, D.L.1
  • 75
    • 0034893582 scopus 로고    scopus 로고
    • Rapid evolution of cisregulatory sequences via local point mutations
    • Stone, J. R., and G. A. Wray. 2001. Rapid evolution of cisregulatory sequences via local point mutations. Mol. Biol. Evol. 18:1764-1770.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 1764-1770
    • Stone, J.R.1    Wray, G.A.2
  • 76
    • 0034712834 scopus 로고    scopus 로고
    • Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby
    • Sucena, E., and D. L. Stern. 2000. Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby. Proc. Natl. Acad. Sci. USA 97:4530-4534.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4530-4534
    • Sucena, E.1    Stern, D.L.2
  • 78
    • 0031669184 scopus 로고    scopus 로고
    • Overlapping genomic sequences: A treasure trove of single-nucleotide polymorphisms
    • Taillon-miller, P., Z. Gu, Q. Li, L. Hillier, and P. Y. Kwok. 1998. Overlapping genomic sequences: A treasure trove of single-nucleotide polymorphisms. Genome Res. 8:748-754.
    • (1998) Genome Res. , vol.8 , pp. 748-754
    • Taillon-miller, P.1    Gu, Z.2    Li, Q.3    Hillier, L.4    Kwok, P.Y.5
  • 79
    • 0034193860 scopus 로고    scopus 로고
    • A high-density single-nucleotide polymorphism map of Xq25-q28
    • Taillon-miller, P., and P. Y. Kwok. 2000. A high-density single-nucleotide polymorphism map of Xq25-q28. Genomics 65:195-202.
    • (2000) Genomics , vol.65 , pp. 195-202
    • Taillon-miller, P.1    Kwok, P.Y.2
  • 80
    • 0033858908 scopus 로고    scopus 로고
    • Evolution of transcriptional regulation
    • Tautz, D. 2000. Evolution of transcriptional regulation. Curr. Opin. Genet. Dev. 10:575-579.
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 575-579
    • Tautz, D.1
  • 81
    • 0040780540 scopus 로고    scopus 로고
    • Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation
    • Terry, C. F., V. Loukaci, and F. R. Green. 2000. Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation. J. Biol. Chem. 275:18138-18144.
    • (2000) J. Biol. Chem. , vol.275 , pp. 18138-18144
    • Terry, C.F.1    Loukaci, V.2    Green, F.R.3
  • 82
    • 0029001881 scopus 로고
    • Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals
    • Tournamille, C., Y. Colin, J. P. Cartron, and C. Le Van Kim. 1995. Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals. Nat. Genet. 10:224-228.
    • (1995) Nat. Genet. , vol.10 , pp. 224-228
    • Tournamille, C.1    Colin, Y.2    Cartron, J.P.3    Le Van Kim, C.4
  • 83
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter, J. C., M. D. Adams, E. W. Myers et al. (271 coauthors). 2001. The sequence of the human genome. Science 291:1304-1351.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 84
    • 0027161022 scopus 로고
    • Mutation of human short tandem repeats
    • Weber, J. L., and C. Wong. 1993. Mutation of human short tandem repeats. Hum. Mol. Genet. 2:1123-1128.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 1123-1128
    • Weber, J.L.1    Wong, C.2
  • 86
    • 0030954180 scopus 로고    scopus 로고
    • Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
    • Wilson, A. G., J. A. Symons, T. L. McDowell H. O. McDevitt, and G. W. Duff. 1997. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc. Natl. Acad. Sci. USA 94:3195-3199.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3195-3199
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3    McDevitt, H.O.4    Duff, G.W.5
  • 87
    • 0029915187 scopus 로고    scopus 로고
    • Transcription of the human corticotropin-releasing hormone gene in NPLC cells is correlated with Z-DNA formation
    • Wolfl, S., C. Martinez, A. Rich, and J. A. Majzoub. 1996. Transcription of the human corticotropin-releasing hormone gene in NPLC cells is correlated with Z-DNA formation. Proc. Natl. Acad. Sci. USA 93:3664-3668.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3664-3668
    • Wolfl, S.1    Martinez, C.2    Rich, A.3    Majzoub, J.A.4
  • 88
    • 0035142523 scopus 로고    scopus 로고
    • Global patterns of human DNA sequence variation in a 10-kb region on chromosome 1
    • Yu, N., Z. Zhao, Y. X. Fu et al. (11 co-authors). 2001. Global patterns of human DNA sequence variation in a 10-kb region on chromosome 1. Mol. Biol. Evol. 18:214-222.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 214-222
    • Yu, N.1    Zhao, Z.2    Fu, Y.X.3
  • 89
    • 0010610371 scopus 로고    scopus 로고
    • Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene
    • Zhao, Y. Y., J. Zhou, C. S. Narayanan, Y. Cui, and A. Kumar. 1999. Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene. Hypertension 33:108-115.
    • (1999) Hypertension , vol.33 , pp. 108-115
    • Zhao, Y.Y.1    Zhou, J.2    Narayanan, C.S.3    Cui, Y.4    Kumar, A.5
  • 90
    • 0033954670 scopus 로고    scopus 로고
    • An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression
    • Zimprich, A., J. Kraus, M. Woltje, P. Mayer, E. Rauch, and V. Hollt. 2000. An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression. J. Neurochem. 74:472-477.
    • (2000) J. Neurochem. , vol.74 , pp. 472-477
    • Zimprich, A.1    Kraus, J.2    Woltje, M.3    Mayer, P.4    Rauch, E.5    Hollt, V.6


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