Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments

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Volumn 7, Issue 3, 2006, Pages 354-364

  Réchards, Marloes ^a   Xia, Weiming ^b   Oorschot, Viola ^a   van Dijk, Suzanne ^a   Annaert, Willem ^c   Selkoe, Dennis J ^b   Klumperman, Judith ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Alzheimer's disease; Amyloid precursor protein; COPI; Immunoelectron microscopy; Intermediate compartment; Membrane traffic; Presenilin 1

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ASPARTIC ACID; GAMMA SECRETASE; MUTANT PROTEIN; PRESENILIN 1; PROTEIN DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; ENDOSOME; GENE CLUSTER; GENE OVEREXPRESSION; GOLGI COMPLEX; HUMAN; HUMAN CELL; KNOCKOUT GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEIN TRANSPORT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHO CELLS; COAT PROTEIN COMPLEX I; CRICETINAE; EMBRYO; ENDOPLASMIC RETICULUM; ENDOSOMES; FIBROBLASTS; GOLGI APPARATUS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, IMMUNOELECTRON; MUTATION; PEPTIDE FRAGMENTS; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT;

EID: 33644652433     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2006.00388.x     Document Type: Article

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