Modeling disease in the mouse: Lessons from DNA damage response and cell cycle control genes

Journal of Cellular Biochemistry

Volumn 97, Issue 3, 2006, Pages 459-473

  Adelman, Carrie A ^a   Petrini, John H J ^a,b   Attwooll, Claire L ^a  

^a Weill Cornell Graduate School of Biomedical Sciences   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Compensation; Genetic modifiers; Mouse models; Penetrance; Strain; Tissue specificity

Indexed keywords

ALLELISM; CANCER; CELL CYCLE REGULATION; DNA DAMAGE; GENE DELETION; GENE EXPRESSION REGULATION; GENE LOSS; GENE TARGETING; GENETIC MANIPULATION; MOLECULAR MODEL; MOUSE; NONHUMAN; PENETRANCE; PHENOTYPIC VARIATION; POINT MUTATION; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE PROTEINS; DISEASE MODELS, ANIMAL; DNA DAMAGE; GENE TARGETING; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASMS; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION;

EID: 33144475989     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20701     Document Type: Review

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