p107 is a suppressor of retinoblastoma development in pRB-deficient mice

Genes and Development

Volumn 12, Issue 11, 1998, Pages 1599-1609

  Robanus Maandag, Els ^a   Dekker, Marleen ^a   Van Der Valk, Martin ^a   Carrozza, Maria Luisa ^a,c   Jeanny, Jean Claude ^b   Dannenberg, Jan Herman ^a   Berns, Anton ^a   Riele, Hein Te ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b CNRS   (France)

^c CNR   (Italy)

Author keywords

10107; Apoptosis; Chimeric mice; Rb; Retinoblastoma; Tumor suppressor gene

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER GENETICS; CANCER SUSCEPTIBILITY; EMBRYO; GENETIC PREDISPOSITION; GENETIC RECOMBINATION; HEMIZYGOSITY; HISTOPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RETINOBLASTOMA; TUMOR SUPPRESSOR GENE;

ANIMALIA;

EID: 2642631746     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.11.1599     Document Type: Article

References (60)

1. Albert, D.M., M. Lahav, R. Lesser, and J. Craft. 1974. Recent observations regarding retinoblastoma, I: Ultrastructure, tissue culture growth, incidence, and animal models. Trans. Ophthalmol. Soc. U.K. 94: 909-928.
2. Al-Ubaidi, M.R., R.L. Font, A.B. Quiambao, M.J. Keener, G.I. Liou, P.A. Overbeek, and W. Baehr. 1992. Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter. J. Cell Biol. 119: 1681-1687.
3. Barnstable, C.J., R. Hofstein, and K. Akagawa. 1985. A marker of early amacrine cell development in rat retina. Brain Res. 20: 286-290.
4. 1 cyclin complexes. Genes & Dev. 9: 1340-1353.
5. Bernards, R. 1997. E2F: A nodal point in cell cycle regulation. Biochim. Biophys. Acta 1333: 33-40.
6. Bjorklund, H., A. Bignami, and D. Dahl. 1985. Immunohistochemical demonstration of glial fibrillary acidic protein in normal rat Müller glia and retinal astrocytes. Neurosci. Lett. 54: 363-368.
7. Bowman, T., H. Symonds, L. Gu, C. Yin, M. Oren, and T. Van Dyke. 1996. Tissue-specific inactivation of p53 tumor suppression in the mouse. Genes & Dev. 10: 826-835.
8. Carter-Dawson, L., R.A. Alvarez, S.-L. Fong, G.I. Liou, H.G. Sperling, and C.D.B. Bridges. 1986. Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding protein (IRBP) during retinal development in normal and rd mutant mice. Dev. Biol. 116: 431-438.
9. Clarke, A.R., E. Robanus Maandag, M. van Roon, N.M.T. van der Lugt, M. van der Valk, M.L. Hooper, A. Berns, and H. te Riele. 1992. Requirement for a functional Rb-1 gene in murine development. Nature 359: 328-330.
10. Claudio, P.P., C.M. Howard, A. Baldi, A. De Luca, Y. Fu, G. Condorelli, Y. Sun, N. Colburn, B. Calabretta, and A. Giordano. 1994. p130/pRB2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRB and p107. Cancer Res. 54: 5556-5560.
11. DeCaprio, J.A., J.W. Ludlow, J. Figge, J.-Y. Shew, C.-M. Huang, W.-H. Lee, E. Marsilio, E. Paucha, and D.M. Livingston. 1988. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54: 275-283.
12. Dietrich, W., H. Katz, S.E. Lincoln, H.-S. Shin, J. Friedman, N.C. Dracopoli, and E.S. Lander. 1992. A genetic map for the mouse suitable for typing intraspecific crosses. Genetics 131: 423-447.
13. Drager, U.C., D.L. Edwards, and C.J. Barnstable. 1984. Antibodies against filamentous proteins in discrete cell types of the mouse retina. J. Neurosci. 4: 2025-2042.
14. Draper, G.J., B.M. Sanders, and J.E. Kingston. 1986. Second primary neoplasms in patients with retinoblastoma. Br. J. Cancer 53: 661-671.
15. Duke-Elder, S. and C. Cook. 1963. Embryology. In System of ophthalmology (ed. S. Duke-Elder), pp. 81-109. Kimpton, London, UK.
16. Dyson, N., P.M. Howley, K. Munger, and E. Harlow. 1989. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243: 934-936.
17. Eisenfeld, A.J., A.H. Bunt-Milam, and P.V. Sarthy. 1984. Müller cell expression of glial fibrillary acidic protein after genetic and experimental photoreceptor degeneration in the rat retina. Invest. Ophthalmol. Vis. Sci. 25: 1321-1328.
18. Ewen, M.E., Y. Xing, J.B. Lawrence, and D.M. Livingston. 1991. Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell 66: 1155-1164.
19. Friend, S.H., J.M. Horowitz, M.R. Gerber, X.-F. Wang, E. Bogenmann, F.P. Li, and R.A. Weinberg. 1987. Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: Organization of the sequence and its encoded protein. Proc. Natl. Acad. Sci. 84: 9059-9063.
20. Gavrieli, Y., Y. Sherman, and S.A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119: 493-501.
21. Hall, M. and G. Peters. 1996. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv. Cancer Res. 68: 67-108.
22. Hannon, G.J., D. Demetrick, and D. Beach. 1993. Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes & Dev. 7: 2378-2391.
23. Harbour, J.W., S.-L. Lai, J. Whang-Peng, A.F. Gazdar, J.D. Minna, and F.J. Kaye. 1988. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241: 353-357.
24. Harlow, E., L.V. Crawford, D.C. Pim, and N.M. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol. 39: 861-869.
25. Hartman, S. and R.C. Mulligan. 1988. Two dominant-acting selectable markers for gene transfer studies in mammalian cells. Proc. Natl. Acad. Sci. 85: 8047-8051.
26. Hooper, M., K. Hardy, A. Handyside, S. Hunter, and M. Monk. 1987. HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 326: 292-295.
27. Horowitz, J.M., S.-H. Park, E. Bogenmann, J.-C. Cheng, D.W. Yandell, F.J. Kaye, J.D. Minna, T.P. Drya, and R.A. Weinberg. 1990. Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc. Natl. Acad. Sci. 87: 2775-2779.
28. Howes, K.A., N. Ransom, D.S. Papermaster, J.G.H. Lasudry, D.M. Albert, and J.J. Windle. 1994. Apoptosis or retinoblasoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes & Dev. 8: 1300-1310.
29. Ivanyi, D., A. Ansink, E. Groeneveld, P.C. Hageman, W.J. Mooi, and A.P.M. Heintz. 1989. New monoclonal antibodies recognizing epidermal differentiation-associated keratins in formalin-fixed, paraffin-embedded tissue. Keratin 10 expression in carcinoma of the vulva. J. Pathol. 159: 7-12.
30. Jacks, T., A. Fazeli, E.M. Schmitt, R.T. Bronson, M.A. Goodell, and R.A. Weinberg. 1992. Effects of an Rb mutation in the mouse. Nature 359: 295-300.
31. Jiang, Z., E. Zacksenhaus, B.L. Gallie, and R.A. Phillips. 1997. The retinoblastoma gene family is differentially expressed during embryogenesis. Oncogene 14: 1789-1797.
32. Kusnetsova, L.E., E.L. Prigogina, H.E. Pogosianz, and B.M. Belkina. 1982. Similar chromosomal abnormalities in several retinoblastomas. Hum. Genet. 61: 201-204.
33. Lacalle, R.A., D. Pulido, J. Vara, M. Zalacaín, and A. Jiménez. 1989. Molecular analysis of the pac gene encoding a puromycin N-acetyl transferase from Streptomyces alboniger. Gene 79: 375-380.
34. Laird, P.W., A. Zijderveld, K. Linders, M.A. Rudnicki, R. Jaenisch, and A. Berns. 1991. Simplified mammalian DNA isolation procedure. Nucleic Acids Res. 19: 4293.
35. Lee, E.Y.-H.P., H. To, J.-Y. Shew, R. Bookstein, P. Scully, and W.-H. Lee. 1988. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 241: 218-221.
36. Lee, E.Y.-H.P., C.-Y. Chang, N. Hu, Y.-C. Wang, C.-C. Lai, K. Herrup, W.-H. Lee, and A. Bradley. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359: 288-294.
37. Lee, M.-H., B.O. Williams, G. Mulligan, S. Mukai, R.T. Bronson, N. Dyson, E. Harlow, and T. Jacks. 1996. Targeted disruption of p107: Functional overlap between p107 and Rb. Genes &. Dev. 10: 1621-1632.
38. Li, Y., C. Graham, S. Lacy, A.M.V. Duncan, and P. Whyte. 1993. The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes & Dev. 7: 2366-2377.
39. Liou, G.I., L. Geng, M.R. Al-Ubaidi, S. Matragoon, G. Hanten, W. Baehr, and P.A. Overbeek. 1990. Tissue-specific expression in transgenic mice directed by the 5′-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding protein. J. Biol. Chem. 265: 8373-8376.
40. Mayol, X., X. Grana, A. Baldi, N. Sang, Q. Hu, and A. Giordano. 1993. Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 8: 2561-2566.
41. McBurney, M.W., L.C. Sutherland, C.N. Adra, B. Leclair, M.A. Rudnicki, and K. Jardine. 1991. The mouse Pgk-1 gene promoter contains an upstream activator sequence. Nucleic Acids Res. 19: 5755-5761.
42. Morgenbesser, S.D., B.O. Williams, T. Jacks, and R.A. DePinho. 1994. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371: 72-74.
43. Mountford, P., B. Zevnik, A. Düwel, J. Nichols, M. Li, C. Dani, M. Robertson, I. Chambers, and A. Smith. 1994. Dicistronic targeting constructs: Reporters and modifiers of mammalian gene expression. Proc. Natl. Acad. Sci. 91: 4303-4307.
44. Nork, T.M., T.L. Schwartz, H.M. Doshi, and L.L. Millecchia. 1995. Retinoblastoma: Cell of origin. Arch. Ophthalmol. 113: 791-802.
45. Qin, X.-Q., D.M. Livingston, M. Ewen, W.R. Sellers, Z. Arany, and W.G. Kaelin Jr. 1995. The transcription factor E2F-1 is a downstream target of RB action. Mol. Cell. Biol. 15: 742-755.
46. Robanus Maandag, E.C., M. van der Valk, M. Vlaar, C. Feltkamp, J. O'Brien, M. van Roon, N. van der Lugt, A. Berns, and H. te Riele. 1994. Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice. EMBO J. 13: 4260-4268.
47. Schmechel, D., P.J. Marangos, and M. Brightman. 1978. Neuron-specific enolase is a molecular marker for peripheral and central neuroendocrine cells. Nature 276: 834-836.
48. Shaulian, E., A. Zauberman, D. Ginsberg, and M. Oren. 1992. Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding. Mol. Cell. Biol. 12: 5581-5592.
49. Sherr, C.J. 1994. G1 phase progression: Cycling on cue. Cell 79: 551-555.
50. Squire, J., R.A. Phillips, S. Boyce, R. Godbout, B. Rogers, and B.L. Gallie. 1984. Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: Verification by standard staining techniques, new densitometric methods, and somatic cell hybridization. Hum. Genet. 66: 46-53.
51. Tarkkanen, A., T. Tervo, K. Tervo, and P. Panula. 1984. Immunohistochemical evidence for preproenkephalin A synthesis in human retinoblastoma. Invest. Ophthalmol. Vis. Sci. 25: 1210-1212.
52. Te Riele, H., E. Robanus Maandag, and A. Berns. 1992. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. 89: 5128-5132.
53. Tsokos, M., A.P. Kyritsis, G.J. Chader, and T.J. Triche. 1986. Differentiation of human retinoblastoma in vitro into cell types with characteristics observed in embryonal or mature retina. Am. J. Pathol. 123: 542-552.
54. Weinberg, R.A. 1995. The retinoblastoma protein and cell cycle control. Cell 81: 323-330.
55. Whyte, P., K.J. Buchkovich, J.M. Horowitz, S.H. Friend, M. Raybuck, R.A. Weinberg, and E. Harlow. 1988. Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 334: 124-129.
56. Williams, B.O., L. Remington, D.M. Albert, S. Mukai, R.T. Bronson, and T. Jacks. 1994a. Cooperative tumorigenic effects of germline mutations in Rb and p53. Nature Genet. 7: 480-484.
57. Williams, B.O., E.M. Schmitt, L. Remington, R.T. Bronson, D.M. Albert, R.A. Weinberg, and T. Jacks. 1994b. Extensive contribution of Kb-deficient cells to adult chimeric mice with limited histopathological consequences. EMBO J. 13: 4251-4259.
58. Young, R.W. 1985. Cell differentiation in the retina of the mouse. Anat. Rec. 212: 199-205.
59. Zacksenhaus, E., Z. Jiang, D. Chung, J.D. Marth, R.A. Phillips, and B.L. Gallie. 1996. pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes & Dev. 10: 3051-3064.
60. Zhu, L., S. van den Heuvel, K. Helin, A. Fattaey, M. Ewen, D. Livingston, N. Dyson, and E. Harlow. 1993. Inhibition of cell proliferation by p 107, a relative of the retinoblastoma protein. Genes & Dev. 7: 1111-1125.