CARD games in apoptosis and immunity

EMBO Reports

Volumn 3, Issue 7, 2002, Pages 616-621

  Bouchier Hayes, Lisa ^a   Martin, Seamus J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CELL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

APOPTOSIS; CLASSIFICATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME STRUCTURE; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNITY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; GENETICS; HUMAN; LYMPHOCYTE; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMAL; APOPTOSIS; CASPASES; ENZYME ACTIVATION; HUMAN; IMMUNITY; LYMPHOCYTES; MODELS, BIOLOGICAL; NF-KAPPA B; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; ANIMALS; HUMANS;

EID: 0036023965     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvf139     Document Type: Review

References (44)

1. Toll-like receptors in the induction of the innate immune response
2. The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
3. The domains of death: Evolution of the apoptosis machinery
4. Defects in regulation of apoptosis in caspase-2-deficient mice
5. The PYRIN domain: A novel motif found in apoptosis and inflammation proteins
6. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB
7. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAPand activates NF-κB
8. CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-κB
9. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death
10. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-κB activation pathways
11. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
12. Plant pathogens and integrated defence responses to infection
13. Regulation of IL-1β generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
14. RAIDD is a new 'death' adaptor molecule
15. Carma1, a CARD-containing binding partner of Bc110, induces Bcl10 phosphorylation and NF-κB activation
16. Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis
17. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
18. Molecular cloning and characterization of DEFCAP-L and S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins
19. The CARD domain: A new apoptotic signalling motif
20. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
21. ICEBERG: A novel inhibitor of interleukin-1β generation
22. RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis
23. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB
24. An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways
25. Human Nod1 confers responsiveness to bacterial lipopolysaccharides
26. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
27. ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases
28. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing
29. Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-κB signaling pathway
30. PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-κB
31. The pyrin domain: A possible member of the death domain-fold family implicated in apoptosis and inflammation
32. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
33. Bimp1, a MAGUK family member linking protein kinase C activation to Bc110-mediated NF-κB induction
34. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
35. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB
36. TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer
37. Invasive Shigella flexneri activates NF-κB through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells
38. Activation of the IκB kinases by RIP via IKKγ/NEMO-mediated oligomerization
39. CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
40. Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis
41. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure
42. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
43. CARD10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with bcl10 and activates NF-κB
44. Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types