Bacterial induction of beta interferon in mice is a function of the lipopolysaccharide component

Infection and Immunity

Volumn 68, Issue 3, 2000, Pages 1600-1607

  Sing, Andreas ^a,c   Merlin, Thomas ^a   Knopf, Hans Peter ^a,d   Nielsen, Peter J ^a   Loppnow, Harald ^b   Galanos, Chris ^a   Freudenberg, Marina A ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b Klin Poliklin fur Inn Med III   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BETA INTERFERON; DOUBLE STRANDED RNA; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; INTERFERON INDUCTION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CYTOKINES; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; INTERFERON TYPE II; INTERFERON-ALPHA; INTERFERON-BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033976514     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.3.1600-1607.2000     Document Type: Article

References (43)

1. Aggarwal, B. B., W. J. Kohr, P. E. Hass, B. Moffat, S. A. Spencer, W. J. Henzel, T. S. Bringman, G. E. Nedwin, D. V. Goeddel, and R. N. Harkins. 1985. Human tumor necrosis factor. Production, purification, and characterization. J. Biol. Chem. 260:2345-2354.
2. Brightbill, H. D., D. H. Libraty, S. R. Krutzik, R. B. Yang, J. T. Belisle, J. R. Bleharski, M. Maitland, M. V. Norgard, S. E. Plevy, S. T. Smale, P. J. Brennan, B. R. Bloom, P. J. Godowski, and R. L. Modlin. 1999. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285:732-736.
3. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
4. Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274:10689-10692.
5. Coutinho, A., and T. Meo. 1978. Genetic bases for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice. Immunogenetics 7:17-24.
6. De, S. K., H. L. Chen, J. L. Pace, J. S. Hunt, P. F. Terranova, and G. C. Enders. 1993. Expression of tumor necrosis factor-alpha in mouse spermatogenic cells. Endocrinology 133:389-396.
7. Dong, Z., X. Qi, and I. J. Fidler. 1993. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J. Exp. Med. 177:1071-1077.
8. Freudenberg, M. A., and C. Galanos. 1991. Tumor necrosis factor alpha mediates lethal activity of killed gram-negative and gram-positive bacteria in D-galactosamine-treated mice. Infect. Immun. 59:2110-2115.
9. Freudenberg, M. A., D. Keppler, and C. Galanos. 1986. Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect. Immun. 51:891-895.
10. Freudenberg, M. A., M. Kopf, and C. Galanos. 1996. Lipopolysaccharide-sensitivity of interferon-g-receptor deficient mice. J. Endotox. Res. 3:291-295.
11. Freudenberg, M. A., Y. Kumazawa, S. Meding, J. Langhorne, and C. Galanos. 1991. Gamma interferon production in endotoxin-responder and -non-responder mice during infection. Infect. Immun. 59:3484-3491.
12. Freudenberg, M. A., R. Salomao, A. Sing, I. Mitov, and C. Galanos. 1998. Reconciling the concepts of endotoxin sensitization and tolerance. Proceedings of the 4th Conference of the International Endotoxin Society. Prog. Clin. Biol. Res. 397:261-268.
13. Fujiki, T., and A. Tanaka. 1988. Antibacterial activity of recombinant murine beta interferon. Infect. Immun. 56:548-551.
14. Galanos, C., O. Lüderitz, and O. Westphal. 1979. Preparation and properties of a standardized lipopolysaccharide from Salmonella abortus equi (Novo-Pyrexal). Zentbl. Bakteriol. Orig. A 243:226-244.
15. Gilman, M. 1993. Ribonuclease protection assay, p. 4.7.1-4.7.8. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Stuhl (ed.), Current protocols in molecular biology, vol. 1. John Wiley and Sons, Inc., New York, N.Y.
16. Hunter, C. A., K. E. Gabriel, T. Radzanowski, L. E. Neyer, and J. S. Remington. 1997. Type 1 interferons enhance production of IFN-gamma by NK cells. Immunol. Lett. 59:1-5.
17. Katschinski, T., C. Galanos, A. Coumbos, and M. A. Freudenberg. 1992. Gamma interferon mediates Propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice. Infect. Immun. 60:1994-2001.
18. Knopf, H. P., F. Otto, R. Engelhardt, M. A. Freudenberg, C. Galanos, F. Herrmann, and R. R. Schumann. 1994. Discordant adaptation of human peritoneal macrophages to stimulation by lipopolysaccharide and the synthetic lipid A analogue SDZ MRL 953. Down-regulation of TNF-alpha and IL-6 is paralleled by an up-regulation of IL-1 beta and granulocyte colony-stimulating factor expression. J. Immunol. 153:287-299.
19. Linder, H., I. Engberg, H. Hoschutzky, I. Mattsby-Baltzer, and C. Svanborg. 1991. Adhesion-dependent activation of mucosal interleukin-6 production. Infect. Immun. 59:4357-4362.
20. Loppnow, H., H. D. Flad, I. Durrbaum, J. Musehold, R. Fetting, A. J. Ulmer, H. Herzbeck, and E. Brandt. 1989. Detection of interleukin 1 with human dermal fibroblasts. Immunobiology 179:283-291.
21. Müller, I., M. Freudenberg, P. Kropf, A. F. Kiderlen, and C. Galanos. 1997. Leishmania major infection in C57BL/10 mice differing at the Lps locus: a new non-healing phenotype. Med. Microbiol. Immunol. 186:75-81.
22. Pennica, D., J. S. Hayflick, T. S. Bringman, M. A. Palladino, and D. V. Goeddel. 1985. Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor. Proc. Natl. Acad. Sci. USA 82:6060-6064.
23. Pestka, S., J. A. Langer, K. C. Zoon, and C. E. Samuel. 1987. Interferons and their actions. Annu. Rev. Biochem. 56:727-777.
24. Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. V. Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, B. Layton, and B. Beutler. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085-2088.
25. Sareneva, T., S. Matikainen, M. Kurimoto, and I. Julkunen. 1998. Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells. J. Immunol. 160:6032-6038.
26. Schwandner, R., R. Dziarski, H. Wesche, M. Rothe, and C. J. Kirschning. 1999. Peptidoglycan-and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J. Biol. Chem. 274:17406-17409.
27. Sen, G. C., and R. M. Ransohoff. 1993. Interferon-induced antiviral actions and their regulation. Adv. Virus Res. 42:57-102.
28. Shimazu, R., S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, and M. Kimoto. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1777-1782.
29. Slade, S. J., and J. Langhorne. 1989. Production of interferon-gamma during infection of mice with Plasmodium chabaudi chabaudi. Immunobiology 179: 353-365.
30. Sultzer, B. M. 1972. Genetic control of host responses to endotoxin. Infect. Immun. 5:107-113.
31. Sun, S., X. Zhang, D. F. Tough, and J. Sprent. 1998. Type I interferon-mediated stimulation of T cells by CpG DNA. J. Exp. Med. 188:2335-2342.
32. d and tumor necrosis factor receptor-deficient mice. Eur. J. Immunol. 26:2686-2692.
33. Tanamoto, K., U. Zähringer, G. R. McKenzie, C. Galanos, E. T. Rietschel, O. Lüderitz, S. Kusumoto, and T. Shiba. 1984. Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate. Infect. Immun. 44:421-426.
34. Tokunaga, T., O. Yano, E. Kuramoto, Y. Kimura, T. Yamamoto, T. Kataoka, and S. Yamamoto. 1992. Synthetic oligonucleotides with particular base sequences from the cDNA encoding proteins of Mycobacterium bovis BCG induce interferons and activate natural killer cells. Microbiol. Immunol. 36:55-66.
35. van den Broek, M. F., U. Müller, S. Huang, M. Aguet, and R. M. Zinkernagel. 1995. Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors. J. Virol. 69:4792-4796.
36. Vogel, S. N. 1992. The Lps gene, p. 485-513. In B. Beutler (ed.), Tumor necrosis factors: the molecules and their emerging role in medicine. Raven Press, New York, N.Y.
37. Vogel, S. N., C. T. Hansen, and D. L. Rosenstreich. 1979. Characterization of a congenitally LPS-resistant, athymic mouse strain. J. Immunol. 122:619-622.
38. d allele: analysis of chromosome 4 markers surrounding the Lps gene. Infect. Immun. 62:4454-4459.
39. Vogel, S. N., L. L. Weedon, L. M. Wahl, and D. L. Rosenstreich. 1982. BCG-induced enhancement of endotoxin sensitivity in C3H/HeJ mice. II. T cell modulation of macrophage sensitivity to LPS in vitro. Immunobiology 160:479-493.
40. Yaegashi, Y., P. Nielsen, A. Sing, C. Galanos, and M. A. Freudenberg. 1995. Interferon beta, a cofactor in the interferon gamma production induced by gram-negative bacteria in mice. J. Exp. Med. 181:953-960.
41. Yamamoto, S., E. Kuramoto, S. Shimada, and T. Tokunaga. 1988. In vitro augmentation of natural killer cell activity and production of interferon-alpha/beta and -gamma with deoxyribonucleic acid fraction from Mycobacterium bovis BCG. Jpn. J. Cancer Res. 79:866-873.
42. Yang, R. B., M. R. Mark, A. Gray, A. Huang, M. H. Xie, M. Zhang, A. Goddard, W. I. Wood, A. L. Gurney, and P. J. Godowski. 1998. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 395:284-288.
43. Yoshimura, A., E. Lien, R. R. Ingalls, E. Tuomanen, R. Dziarski, and D. Golenbock. 1999. Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol. 163:1-5.