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Volumn 173, Issue 3, 2004, Pages 1858-1867

Endogenous expression of activation-induced cytidine deaminase in cell line WEHI-231

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; DEOXYURIDINE; DNA GLYCOSYLTRANSFERASE; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN EPSILON; IMMUNOGLOBULIN G2B; UNCLASSIFIED DRUG;

EID: 3242777574     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.3.1858     Document Type: Article
Times cited : (10)

References (50)
  • 2
    • 0022529563 scopus 로고
    • Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products
    • Jakway, J. P., W. R. Usinger, M. R. Gold, R. I. Mishell, and A. L. DeFranco. 1986. Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products. J. Immunol. 137:2225.
    • (1986) J. Immunol. , vol.137 , pp. 2225
    • Jakway, J.P.1    Usinger, W.R.2    Gold, M.R.3    Mishell, R.I.4    DeFranco, A.L.5
  • 3
    • 0023902425 scopus 로고
    • Role of phosphoinositide-derived second messengers in mediating anti-IgM-induced growth arrest of WEHI-231 B lymphoma cells
    • Page, D. M., and A. L. DeFranco. 1988. Role of phosphoinositide-derived second messengers in mediating anti-IgM-induced growth arrest of WEHI-231 B lymphoma cells. J. Immunol. 140:3717.
    • (1988) J. Immunol. , vol.140 , pp. 3717
    • Page, D.M.1    DeFranco, A.L.2
  • 4
    • 0019451918 scopus 로고
    • The regulation of growth and differentiation of a murine B cell lymphoma. II. The inhibition of WEHI 231 by anti-immunoglobulin antibodies
    • Boyd, A. W., and J. W. Schrader. 1981. The regulation of growth and differentiation of a murine B cell lymphoma. II. The inhibition of WEHI 231 by anti-immunoglobulin antibodies. J. Immunol. 126:2466.
    • (1981) J. Immunol. , vol.126 , pp. 2466
    • Boyd, A.W.1    Schrader, J.W.2
  • 6
  • 8
    • 0035871625 scopus 로고    scopus 로고
    • Increased transcription levels induce higher mutation rates in a hypermutating cell line
    • Bachl, J., C. Carlson, V. Gray-Schopfer, M. Dessing, and C. Olsson. 2001. Increased transcription levels induce higher mutation rates in a hypermutating cell line. J. Immunol. 166:5051.
    • (2001) J. Immunol. , vol.166 , pp. 5051
    • Bachl, J.1    Carlson, C.2    Gray-Schopfer, V.3    Dessing, M.4    Olsson, C.5
  • 9
    • 0032858194 scopus 로고    scopus 로고
    • Molecular processes that regulate class switching
    • Stavnezer, J. 2000. Molecular processes that regulate class switching. Curr. Top. Microbiol. Immunol. 245:127.
    • (2000) Curr. Top. Microbiol. Immunol. , vol.245 , pp. 127
    • Stavnezer, J.1
  • 10
    • 0037074975 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
    • Martin, A., P. D. Bardwell, C. J. Woo, M. Fan, M. J. Shulman, and M. D. Scharff. 2002. Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas. Nature 415:802.
    • (2002) Nature , vol.415 , pp. 802
    • Martin, A.1    Bardwell, P.D.2    Woo, C.J.3    Fan, M.4    Shulman, M.J.5    Scharff, M.D.6
  • 11
    • 0141992113 scopus 로고    scopus 로고
    • C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
    • Barreto, V., B. Reina-San-Martin, A. R. Ramiro, K. M. McBride, and M. C. Nussenzweig. 2003. C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol. Cell 12:501.
    • (2003) Mol. Cell , vol.12 , pp. 501
    • Barreto, V.1    Reina-San-Martin, B.2    Ramiro, A.R.3    McBride, K.M.4    Nussenzweig, M.C.5
  • 13
    • 0032549125 scopus 로고    scopus 로고
    • Mismatch repair coopted by hypermutation
    • Cascalho, M., J. Wong, C. Steinberg, and M. Wabl. 1998. Mismatch repair coopted by hypermutation. Science 279:1207.
    • (1998) Science , vol.279 , pp. 1207
    • Cascalho, M.1    Wong, J.2    Steinberg, C.3    Wabl, M.4
  • 14
    • 0032127804 scopus 로고    scopus 로고
    • Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
    • Rada, C., M. R. Ehrenstein, M. S. Neuberger, and C. Milstein. 1998. Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting. Immunity 9:135.
    • (1998) Immunity , vol.9 , pp. 135
    • Rada, C.1    Ehrenstein, M.R.2    Neuberger, M.S.3    Milstein, C.4
  • 15
    • 0032101611 scopus 로고    scopus 로고
    • Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein
    • Phung, Q. H., D. B. Winter, A. Cranston, R. E. Tarone, V. A. Bohr, R. Fishel, and P. J. Gearhart. 1998. Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J. Exp. Med. 187:1745.
    • (1998) J. Exp. Med. , vol.187 , pp. 1745
    • Phung, Q.H.1    Winter, D.B.2    Cranston, A.3    Tarone, R.E.4    Bohr, V.A.5    Fishel, R.6    Gearhart, P.J.7
  • 16
    • 0033526760 scopus 로고    scopus 로고
    • Different mismatch repair deficiencies all have the same effects on somatic hypermutation: Intact primary mechanism accompanied by secondary modifications
    • Kim, N., G. Bozek, J. C. Lo, and U. Storb. 1999. Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications. J. Exp. Med. 190:21.
    • (1999) J. Exp. Med. , vol.190 , pp. 21
    • Kim, N.1    Bozek, G.2    Lo, J.C.3    Storb, U.4
  • 17
    • 0037026482 scopus 로고    scopus 로고
    • Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
    • Di Noia, J., and M. S. Neuberger. 2002. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature 419:43.
    • (2002) Nature , vol.419 , pp. 43
    • Di Noia, J.1    Neuberger, M.S.2
  • 18
    • 0033564878 scopus 로고    scopus 로고
    • Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: Parallels with somatic hypermutation
    • Ehrenstein, M. R., and M. S. Neuberger. 1999. Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation. EMBO J. 18:3484.
    • (1999) EMBO J. , vol.18 , pp. 3484
    • Ehrenstein, M.R.1    Neuberger, M.S.2
  • 19
    • 0037017390 scopus 로고    scopus 로고
    • Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions
    • Schrader, C. E., J. Vardo, and J. Stavnezer. 2002. Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions. J. Exp. Med. 195:367.
    • (2002) J. Exp. Med. , vol.195 , pp. 367
    • Schrader, C.E.1    Vardo, J.2    Stavnezer, J.3
  • 21
    • 0037108463 scopus 로고    scopus 로고
    • Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNO-deficient mice
    • Rada, C., G. T. Williams, H. Nilsen, D. E. Barnes, T. Lindahl, and M. S. Neuberger. 2002. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNO-deficient mice. Can. Biol. 12:1748.
    • (2002) Can. Biol. , vol.12 , pp. 1748
    • Rada, C.1    Williams, G.T.2    Nilsen, H.3    Barnes, D.E.4    Lindahl, T.5    Neuberger, M.S.6
  • 24
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching
    • Rolink, A., F. Melchers, and J. Andersson. 1996. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity 5:319.
    • (1996) Immunity , vol.5 , pp. 319
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 25
    • 0036224604 scopus 로고    scopus 로고
    • IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
    • Manis, J. P., D. Dudley, L. Kaylor, and F. W. Alt. 2002. IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. Immunity 16:607.
    • (2002) Immunity , vol.16 , pp. 607
    • Manis, J.P.1    Dudley, D.2    Kaylor, L.3    Alt, F.W.4
  • 27
    • 0033560796 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase
    • Smith, G. C., and S. P. Jackson. 1999. The DNA-dependent protein kinase. Genes Dev. 13:916.
    • (1999) Genes Dev. , vol.13 , pp. 916
    • Smith, G.C.1    Jackson, S.P.2
  • 30
    • 0037866984 scopus 로고    scopus 로고
    • H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
    • Reina-San-Martin, B., S. Difilippantonio, L. Hanitsch, R. F. Masilamani, A. Nussenzweig, and M. C. Nussenzweig. 2003. H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. J. Exp. Med. 197:1767.
    • (2003) J. Exp. Med. , vol.197 , pp. 1767
    • Reina-San-Martin, B.1    Difilippantonio, S.2    Hanitsch, L.3    Masilamani, R.F.4    Nussenzweig, A.5    Nussenzweig, M.C.6
  • 32
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102:553.
    • (2000) Cell , vol.102 , pp. 553
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 33
    • 0022498511 scopus 로고
    • High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene
    • Meyer, J., H. M. Jack, N. Ellis, and M. Wabl. 1986. High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene. Proc. Natl. Acad. Sci. USA 83:6950.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6950
    • Meyer, J.1    Jack, H.M.2    Ellis, N.3    Wabl, M.4
  • 34
    • 0019422455 scopus 로고
    • Expression of mu and γ immunoglobulin heavy chains in different cells of a cloned mouse lymphoid line
    • Burrows, P. D., G. B. Beck, and M. R. Wabl. 1981. Expression of mu and γ immunoglobulin heavy chains in different cells of a cloned mouse lymphoid line. Proc. Natl. Acad. Sci. USA 78:564.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 564
    • Burrows, P.D.1    Beck, G.B.2    Wabl, M.R.3
  • 35
    • 0142061077 scopus 로고    scopus 로고
    • Mutations in AID and UNG extend the function of AID
    • Li, Z., C. J. Woo, and M. D. Scharff. 2003. Mutations in AID and UNG extend the function of AID. Nat. Immunol. 4:945.
    • (2003) Nat. Immunol. , vol.4 , pp. 945
    • Li, Z.1    Woo, C.J.2    Scharff, M.D.3
  • 36
    • 0030841051 scopus 로고    scopus 로고
    • Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNO gene
    • Nilsen, H., M. Otterlei, T. Haug, K. Solum, T. A. Nagelhus, F. Skorpen, and H. E. Krokan. 1997. Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNO gene. Nucleic Acids Res. 25:750.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 750
    • Nilsen, H.1    Otterlei, M.2    Haug, T.3    Solum, K.4    Nagelhus, T.A.5    Skorpen, F.6    Krokan, H.E.7
  • 37
    • 0032531934 scopus 로고    scopus 로고
    • Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively
    • Otterlei, M., T. Haug, T. A. Nagelhus, G. Slupphaug, T. Lindmo, and H. E. Krokan. 1998. Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively. Nucleic Acids Res. 26:4611.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 4611
    • Otterlei, M.1    Haug, T.2    Nagelhus, T.A.3    Slupphaug, G.4    Lindmo, T.5    Krokan, H.E.6
  • 38
    • 0024312603 scopus 로고
    • Translation affects immunoglobulin mRNA stability
    • Jack, H. M., J. Berg, and M. Wabl. 1989. Translation affects immunoglobulin mRNA stability. Eur. J. Immunol. 19:843.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 843
    • Jack, H.M.1    Berg, J.2    Wabl, M.3
  • 39
    • 0026443954 scopus 로고
    • Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
    • Rogozin, I. B., and N. A. Kolchanov. 1992. Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim. Biophys. Acta 1171:11.
    • (1992) Biochim. Biophys. Acta , vol.1171 , pp. 11
    • Rogozin, I.B.1    Kolchanov, N.A.2
  • 40
    • 0031460776 scopus 로고    scopus 로고
    • Critical test of hot spot motifs for immunoglobulin hypermutation
    • Bachl, J., C. Steinberg, and M. Wabl. 1997. Critical test of hot spot motifs for immunoglobulin hypermutation. Eur. J. Immunol. 27:3398.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3398
    • Bachl, J.1    Steinberg, C.2    Wabl, M.3
  • 43
    • 0037126038 scopus 로고    scopus 로고
    • Somatic hypermutation of the AID transgene in B and non-B cells
    • Martin, A., and M. D. Scharff. 2002. Somatic hypermutation of the AID transgene in B and non-B cells. Proc. Natl. Acad. Sci. USA 99:12304.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12304
    • Martin, A.1    Scharff, M.D.2
  • 44
    • 0019452362 scopus 로고
    • Thirteen hybridomas secreting hapten-specific immunoglobulin E from mice with Iga or Igb heavy chain haplotype
    • Rudolph, A. K., P. D. Burrows, and M. R. Wabl. 1981. Thirteen hybridomas secreting hapten-specific immunoglobulin E from mice with Iga or Igb heavy chain haplotype. Eur. J. Immunol. 11:527.
    • (1981) Eur. J. Immunol. , vol.11 , pp. 527
    • Rudolph, A.K.1    Burrows, P.D.2    Wabl, M.R.3
  • 45
    • 0022599997 scopus 로고
    • Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching
    • Stavnezer-Nordgren, J., and S. Sirlin. 1986. Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching. EMBO J. 5:95.
    • (1986) EMBO J. , vol.5 , pp. 95
    • Stavnezer-Nordgren, J.1    Sirlin, S.2
  • 46
    • 0025159276 scopus 로고
    • Structure and expression of murine germ-line immunoglobulin ε heavy chain transcripts induced by interleukin 4
    • Gerondakis, S. 1990. Structure and expression of murine germ-line immunoglobulin ε heavy chain transcripts induced by interleukin 4. Proc. Natl. Acad. Sci. USA 87:1581.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1581
    • Gerondakis, S.1
  • 47
    • 0023932604 scopus 로고
    • Structure and expression of germ line immunoglobulin γ 2b transcripts
    • Lutzker, S., and F. W. Alt. 1988. Structure and expression of germ line immunoglobulin γ 2b transcripts. Mol. Cell. Biol. 8:1849.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 1849
    • Lutzker, S.1    Alt, F.W.2
  • 49
    • 0028968667 scopus 로고
    • Switch transcripts in immunoglobulin class switching
    • Lorenz, M., S. Jung, and A. Radbruch. 1995. Switch transcripts in immunoglobulin class switching. Science 267:1825.
    • (1995) Science , vol.267 , pp. 1825
    • Lorenz, M.1    Jung, S.2    Radbruch, A.3
  • 50
    • 0037087306 scopus 로고    scopus 로고
    • Two new isotype-specific switching activities detected for Ig class switching
    • Ma, L., H. H. Wortis, and A. L. Kenter. 2002. Two new isotype-specific switching activities detected for Ig class switching. J. Immunol. 168:2835.
    • (2002) J. Immunol. , vol.168 , pp. 2835
    • Ma, L.1    Wortis, H.H.2    Kenter, A.L.3


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