-
1
-
-
0031041155
-
The promotion of V region hypermutation
-
Scharff, M. D., Poltoratsky, V. and Green, N. S., The promotion of V region hypermutation. J. Exp. Med. 1997. 187: 185-188.
-
(1997)
J. Exp. Med.
, vol.187
, pp. 185-188
-
-
Scharff, M.D.1
Poltoratsky, V.2
Green, N.S.3
-
3
-
-
0029992777
-
The targeting of somatic hypermutation
-
Jolly, C. J., Wagner, S. D., Rada, C., Klix, N., Milstein, C. and Neuberger, M. S., The targeting of somatic hypermutation. Semin. Immunol. 1996. 8: 159-161.
-
(1996)
Semin. Immunol.
, vol.8
, pp. 159-161
-
-
Jolly, C.J.1
Wagner, S.D.2
Rada, C.3
Klix, N.4
Milstein, C.5
Neuberger, M.S.6
-
4
-
-
0030012520
-
Introduction: What mechanism(s) drive hypermutation?
-
Reynaud, C. A., Quint, L., Bertocci, B. and Weill, J. C., Introduction: what mechanism(s) drive hypermutation? Semin. Immunol. 1996. 8: 125-129.
-
(1996)
Semin. Immunol.
, vol.8
, pp. 125-129
-
-
Reynaud, C.A.1
Quint, L.2
Bertocci, B.3
Weill, J.C.4
-
5
-
-
0029927054
-
The mechanism of somatic hypermutation studied with transgenic and transfected target genes
-
Storb, U., Peters, A., Klotz, E., Rogerson, B. and Hackett, J. Jr, The mechanism of somatic hypermutation studied with transgenic and transfected target genes. Semin. Immunol. 1996. 8: 131-140.
-
(1996)
Semin. Immunol.
, vol.8
, pp. 131-140
-
-
Storb, U.1
Peters, A.2
Klotz, E.3
Rogerson, B.4
Hackett Jr., J.5
-
6
-
-
0029996999
-
Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches
-
Tumas-Brundage, K., Vora, K. A., Giusti, A. M. and Manser, T., Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches. Semin. Immunol. 1996. 8: 141-150.
-
(1996)
Semin. Immunol.
, vol.8
, pp. 141-150
-
-
Tumas-Brundage, K.1
Vora, K.A.2
Giusti, A.M.3
Manser, T.4
-
7
-
-
0029883777
-
Affinity maturation and class switching
-
Wabl, M. and Steinberg, C., Affinity maturation and class switching. Curr. Opin. Immunol. 1996. 8: 89-92.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 89-92
-
-
Wabl, M.1
Steinberg, C.2
-
9
-
-
0022386943
-
Molecular events during maturation of the immune response to oxazolone
-
Berek, C., Griffiths, G. M. and Milstein, C., Molecular events during maturation of the immune response to oxazolone. Nature 1985. 316: 412-418.
-
(1985)
Nature
, vol.316
, pp. 412-418
-
-
Berek, C.1
Griffiths, G.M.2
Milstein, C.3
-
10
-
-
0023722177
-
Mutational hot spots in Ig V region genes of human follicular lymphomas
-
Levy, S., Mendel, E., Kon, S., Avnur, Z. and Levy, R., Mutational hot spots in Ig V region genes of human follicular lymphomas. J. Exp. Med. 1988. 168: 475-489.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 475-489
-
-
Levy, S.1
Mendel, E.2
Kon, S.3
Avnur, Z.4
Levy, R.5
-
11
-
-
0027499308
-
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: Clustering, polarity, and specific hot spots
-
Betz, A. G., Rada, C., Pannell, R., Milstein, C. and Neuberger, M. S., Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proc. Natl. Acad. Sci. USA 1993. 90: 2385-2388.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2385-2388
-
-
Betz, A.G.1
Rada, C.2
Pannell, R.3
Milstein, C.4
Neuberger, M.S.5
-
12
-
-
0029067875
-
Targeting of non-lg sequences in place of the V segment by somatic hypermutation
-
Yelamos, J., Klix, N., Goyenechea, B., Lozano, F., Chui, Y. L., Gonzalez-Fernandez, A., Pannell, R., Neuberger, M. S. and Milstein, C., Targeting of non-lg sequences in place of the V segment by somatic hypermutation. Nature 1995. 376: 225-229.
-
(1995)
Nature
, vol.376
, pp. 225-229
-
-
Yelamos, J.1
Klix, N.2
Goyenechea, B.3
Lozano, F.4
Chui, Y.L.5
Gonzalez-Fernandez, A.6
Pannell, R.7
Neuberger, M.S.8
Milstein, C.9
-
13
-
-
0028577994
-
Somatic mutation of immunoglobulin lambda chains: A segment of the major intron hypermutates as much as the complementarity-determining regions
-
Gonzalez-Fernandez, A., Gupta, S. K., Pannell, R., Neuberger, M. S. and Milstein, C., Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions. Proc. Natl. Acad. Sci. USA 1994. 91: 12614-12618.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12614-12618
-
-
Gonzalez-Fernandez, A.1
Gupta, S.K.2
Pannell, R.3
Neuberger, M.S.4
Milstein, C.5
-
14
-
-
0031569118
-
Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
-
Dorner, T., Brezinschek, H. P., Brezinschek, R. I., Foster, S. J., Domiati-Saad, R. and Lipsky, P. E., Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J. Immunol. 1997. 158: 2779-2789.
-
(1997)
J. Immunol.
, vol.158
, pp. 2779-2789
-
-
Dorner, T.1
Brezinschek, H.P.2
Brezinschek, R.I.3
Foster, S.J.4
Domiati-Saad, R.5
Lipsky, P.E.6
-
15
-
-
0029947265
-
Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells
-
Smith, D. S., Creadon, G., Jena, P. K., Portanova, J. P., Kotzin, B. L. and Wysocki, L. J., Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J. Immunol. 1996. 156: 2642-2652.
-
(1996)
J. Immunol.
, vol.156
, pp. 2642-2652
-
-
Smith, D.S.1
Creadon, G.2
Jena, P.K.3
Portanova, J.P.4
Kotzin, B.L.5
Wysocki, L.J.6
-
16
-
-
0027227311
-
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
-
Betz, A. G., Neuberger, M. S. and Milstein, C., Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol. Today 1993. 14: 405-411.
-
(1993)
Immunol. Today
, vol.14
, pp. 405-411
-
-
Betz, A.G.1
Neuberger, M.S.2
Milstein, C.3
-
17
-
-
0029097283
-
Codon bias targets mutation
-
Wagner, S. D., Milstein, C. and Neuberger, M. S., Codon bias targets mutation. Nature 1995. 376: 732.
-
(1995)
Nature
, vol.376
, pp. 732
-
-
Wagner, S.D.1
Milstein, C.2
Neuberger, M.S.3
-
18
-
-
0026443954
-
Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
-
Rogozin, I. B. and Kolchanov, N. A., Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim. Biophys. Acta 1992. 1171: 11-18.
-
(1992)
Biochim. Biophys. Acta
, vol.1171
, pp. 11-18
-
-
Rogozin, I.B.1
Kolchanov, N.A.2
-
19
-
-
0030450401
-
Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation
-
Goyenechea, B. and Milstein, C., Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation. Proc. Natl. Acad. Sci. USA 1996. 93: 13979-13984.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13979-13984
-
-
Goyenechea, B.1
Milstein, C.2
-
20
-
-
0028968928
-
A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene
-
Zhu, M., Rabinowitz, J. L., Green, N. S., Kobrin, B. J. and Scharff, M. D., A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene. Proc. Natl. Acad. Sci. USA 1995. 92: 2810-2814.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2810-2814
-
-
Zhu, M.1
Rabinowitz, J.L.2
Green, N.S.3
Kobrin, B.J.4
Scharff, M.D.5
-
21
-
-
0029047213
-
Immunoglobulin variable region hypermutation in hybrids derived from a pre-B- and a myeloma cell line
-
Green, N. S., Rabinowitz, J. L., Zhu, M., Kobrin, B. J. and Scharff, M. D., Immunoglobulin variable region hypermutation in hybrids derived from a pre-B- and a myeloma cell line. Proc. Natl. Acad. Sci. USA 1995. 92: 6304-6308.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6304-6308
-
-
Green, N.S.1
Rabinowitz, J.L.2
Zhu, M.3
Kobrin, B.J.4
Scharff, M.D.5
-
22
-
-
0030071749
-
An immunoglobulin mutator that targets G.C base pairs
-
Bachl, J. and Wabl, M., An immunoglobulin mutator that targets G.C base pairs. Proc. Natl. Acad. Sci. USA 1996. 93: 851-855.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 851-855
-
-
Bachl, J.1
Wabl, M.2
-
23
-
-
0029965649
-
Enhancers of hypermutation
-
Bachl, J. and Wabl, M., Enhancers of hypermutation. Immunogenetics 1996. 45: 59-64.
-
(1996)
Immunogenetics
, vol.45
, pp. 59-64
-
-
Bachl, J.1
Wabl, M.2
-
24
-
-
0345975560
-
Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line
-
Wabl, M., Burrows, P. D., von Gabain, A. and Steinberg, C., Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line. Proc. Natl. Acad. Sci. USA 1985. 82: 479-482.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 479-482
-
-
Wabl, M.1
Burrows, P.D.2
Von Gabain, A.3
Steinberg, C.4
-
25
-
-
0022498511
-
High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene
-
Meyer, J., Jäck, H.-M., Ellis, N. and Wabl, M., High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene. Proc. Natl. Acad. Sci. USA 1986. 83: 6950-6953.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 6950-6953
-
-
Meyer, J.1
Jäck, H.-M.2
Ellis, N.3
Wabl, M.4
-
26
-
-
0029557884
-
A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro
-
Wu, H., Pelkonen, E., Knuutila, S. and Kaartinen, M., A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro. Eur. J. Immunol. 1995. 25: 3263-3269.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 3263-3269
-
-
Wu, H.1
Pelkonen, E.2
Knuutila, S.3
Kaartinen, M.4
-
27
-
-
0023972405
-
Looping out and deletion mechanism for the immunoglobulin heavy-chain class switch
-
Jäck, H.-M., McDowell, M., Steinberg, C. M. and Wabl, M., Looping out and deletion mechanism for the immunoglobulin heavy-chain class switch. Proc. Natl. Acad. Sci. USA 1988. 85: 1581-1585.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1581-1585
-
-
Jäck, H.-M.1
McDowell, M.2
Steinberg, C.M.3
Wabl, M.4
-
28
-
-
0020471790
-
Multiple immunoglobulin heavy-chain gene transcripts in Abelson murine leukemia virus-transformed lymphoid cell lines
-
Alt, F. W., Rosenberg, N., Enea, V., Siden, E. and Baltimore, D., Multiple immunoglobulin heavy-chain gene transcripts in Abelson murine leukemia virus-transformed lymphoid cell lines. Mol. Cell Biol. 1982. 2: 386-400.
-
(1982)
Mol. Cell Biol.
, vol.2
, pp. 386-400
-
-
Alt, F.W.1
Rosenberg, N.2
Enea, V.3
Siden, E.4
Baltimore, D.5
-
29
-
-
0023378035
-
High rates of deletions in the constant region segment of the immunoglobulin mu gene
-
Jäck, H.-M. and Wabl, M., High rates of deletions in the constant region segment of the immunoglobulin mu gene. Proc. Natl. Acad. Sci. USA 1987. 84: 4934-4938.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 4934-4938
-
-
Jäck, H.-M.1
Wabl, M.2
-
30
-
-
0023161408
-
Measurements of mutation rates in B lymphocytes
-
Wabl, M., Jäck, H.-M., Meyer, J., Beck-Engeser, G., von Borstel, R. C. and Steinberg, C. M., Measurements of mutation rates in B lymphocytes. Immunol. Rev. 1987. 96: 91-107.
-
(1987)
Immunol. Rev.
, vol.96
, pp. 91-107
-
-
Wabl, M.1
Jäck, H.-M.2
Meyer, J.3
Beck-Engeser, G.4
Von Borstel, R.C.5
Steinberg, C.M.6
-
31
-
-
0019422455
-
Expression of mu and gamma immunoglobulin heavy chains in different cells of a cloned mouse lymphoid line
-
Burrows, P. D., Beck, G. B. and Wabl, M. R., Expression of mu and gamma immunoglobulin heavy chains in different cells of a cloned mouse lymphoid line. Proc. Natl. Acad. Sci. USA 1981. 78: 564-568.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 564-568
-
-
Burrows, P.D.1
Beck, G.B.2
Wabl, M.R.3
-
32
-
-
0021055938
-
Immunoglobulin heavy-chain class switching in a pre-B cell line is accompanied by DNA rearrangement
-
Burrows, P. D., Beck-Engeser, G. B. and Wabl, M. R., Immunoglobulin heavy-chain class switching in a pre-B cell line is accompanied by DNA rearrangement. Nature 1983. 306: 243-246.
-
(1983)
Nature
, vol.306
, pp. 243-246
-
-
Burrows, P.D.1
Beck-Engeser, G.B.2
Wabl, M.R.3
-
33
-
-
0021930187
-
Critical test of a sister chromatid exchange model for the immunoglobulin heavy-chain class switch
-
Wabl, M., Meyer, J., Beck-Engeser, G., Tenkhoff, M. and Burrows, P. D., Critical test of a sister chromatid exchange model for the immunoglobulin heavy-chain class switch. Nature 1985. 313: 687-689.
-
(1985)
Nature
, vol.313
, pp. 687-689
-
-
Wabl, M.1
Meyer, J.2
Beck-Engeser, G.3
Tenkhoff, M.4
Burrows, P.D.5
-
34
-
-
0026470596
-
What limits affinity maturation of antibodies in Xenopus - The rate of somatic mutation or the ability to select mutants?
-
Wilson, M., Hsu, E., Marcuz, A., Courtet, M., Du Pasquier, L. and Steinberg, C., What limits affinity maturation of antibodies in Xenopus - the rate of somatic mutation or the ability to select mutants? EMBO J. 1992. 11: 4337-4347.
-
(1992)
EMBO J.
, vol.11
, pp. 4337-4347
-
-
Wilson, M.1
Hsu, E.2
Marcuz, A.3
Courtet, M.4
Du Pasquier, L.5
Steinberg, C.6
-
35
-
-
0028811073
-
Somatic mutations during an immune response in Xenopus tadpoles
-
Wilson, M., Marcuz, A. and Du Pasquier, L., Somatic mutations during an immune response in Xenopus tadpoles. Dev. Immunol. 1995. 4: 227-234.
-
(1995)
Dev. Immunol.
, vol.4
, pp. 227-234
-
-
Wilson, M.1
Marcuz, A.2
Du Pasquier, L.3
|