Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells

Biochemical Pharmacology

Volumn 65, Issue 10, 2003, Pages 1603-1610

  Walle, Thomas ^a   Vincent, Timothy S ^a   Walle, U Kristina ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Caco 2 cells; Covalent binding; DNA and protein; Flavonoids; Hep G2 cells; Peroxidative metabolism; Quercetin

Indexed keywords

ANAZOLENE SODIUM; CARBON 14; CELL PROTEIN; DNA; FLAVONOID; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; PEROXIDASE; PROTEIN; QUERCETIN; QUINONE DERIVATIVE;

ARTICLE; AUTORADIOGRAPHY; CELL LYSATE; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CELL TYPE; CONTROLLED STUDY; COVALENT BOND; DNA BINDING; DNA ISOLATION; DNA PURIFICATION; DRUG DNA BINDING; DRUG EFFECT; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; INCUBATION TIME; INTESTINE CELL; ISOTOPE LABELING; LIQUID SCINTILLATION COUNTING; LIVER CELL; LIVER MICROSOME; OXIDATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PURIFICATION; STAINING;

EID: 0038730962     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00151-5     Document Type: Article

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