-
1
-
-
0034671387
-
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
-
Ando Y, Saka H, Ando M, Sawa T, Muro K, Ueoka H, Yokoyama A, Saitoh S, Shimokata K, and Hasegawa Y (2000) Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res 60: 6921-6926.
-
(2000)
Cancer Res
, vol.60
, pp. 6921-6926
-
-
Ando, Y.1
Saka, H.2
Ando, M.3
Sawa, T.4
Muro, K.5
Ueoka, H.6
Yokoyama, A.7
Saitoh, S.8
Shimokata, K.9
Hasegawa, Y.10
-
2
-
-
0036148810
-
Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan
-
Ando Y, Ueoka H, Sugiyama T, Ichiki M, Shimokata K, and Hasegawa Y (2002) Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan. Ther Drug Monit 24:111-116.
-
(2002)
Ther Drug Monit
, vol.24
, pp. 111-116
-
-
Ando, Y.1
Ueoka, H.2
Sugiyama, T.3
Ichiki, M.4
Shimokata, K.5
Hasegawa, Y.6
-
3
-
-
0025858296
-
Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion
-
Atsumi R, Suzuki W, and Hakusui H (1991) Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion. Xenobiotica 21:1159-1169.
-
(1991)
Xenobiotica
, vol.21
, pp. 1159-1169
-
-
Atsumi, R.1
Suzuki, W.2
Hakusui, H.3
-
4
-
-
0028867826
-
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
-
Bosma PJ, Chowdhury JR, Bakker C, Gantla S, De Boer A, Oostra BA, Lindhout D, Tytgat GNJ, Jansen PLM, Elferink RPJO, et al. (1995) The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 333:1171-1175.
-
(1995)
N Engl J Med
, vol.333
, pp. 1171-1175
-
-
Bosma, P.J.1
Chowdhury, J.R.2
Bakker, C.3
Gantla, S.4
De Boer, A.5
Oostra, B.A.6
Lindhout, D.7
Tytgat, G.N.J.8
Jansen, P.L.M.9
Elferink, R.P.J.O.10
-
5
-
-
0033600191
-
Glucuronidation of 7-ethyl-10 hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltranferases encoded at the UGT1 locus
-
Ciotti M, Basu N, Brangi M, and Owens IS (1999) Glucuronidation of 7-ethyl-10 hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltranferases encoded at the UGT1 locus. Biochem Biophys Res Communun 260:199-202.
-
(1999)
Biochem Biophys Res Communun
, vol.260
, pp. 199-202
-
-
Ciotti, M.1
Basu, N.2
Brangi, M.3
Owens, I.S.4
-
6
-
-
0027972726
-
Topoisomerase I inhibitors: Topotecan and irenotecan
-
Creemers GJ, Lund B, and Verweij J (1994) Topoisomerase I inhibitors: topotecan and irenotecan. Cancer Treat Rev 20:73-96.
-
(1994)
Cancer Treat Rev
, vol.20
, pp. 73-96
-
-
Creemers, G.J.1
Lund, B.2
Verweij, J.3
-
7
-
-
0035864844
-
Phase II study of irinotecan as first-line chemotherapy for patients with advanced colorectal carcinoma
-
Firvida JL, Irigoyen A, Vazquez-Estevez S, Diz P, Constenla M, Casal-Rubio J, Valladares-Ayerbes M, Castellanos J, Rodriguez R, and Balcells M (2001) Phase II study of irinotecan as first-line chemotherapy for patients with advanced colorectal carcinoma. Cancer 91:704-711.
-
(2001)
Cancer
, vol.91
, pp. 704-711
-
-
Firvida, J.L.1
Irigoyen, A.2
Vazquez-Estevez, S.3
Diz, P.4
Constenla, M.5
Casal-Rubio, J.6
Valladares-Ayerbes, M.7
Castellanos, J.8
Rodriguez, R.9
Balcells, M.10
-
8
-
-
0036765309
-
Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7 ethyl-10-hydroxycamptothecin (SN-38)
-
Gagné J-F, Montminy V, Belanger P, Journault K, Gaucher G, and Guillemette C (2002) Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7 ethyl-10-hydroxycamptothecin (SN-38). Mol Pharmacol 62:608-617.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 608-617
-
-
Gagné, J.-F.1
Montminy, V.2
Belanger, P.3
Journault, K.4
Gaucher, G.5
Guillemette, C.6
-
9
-
-
0034950281
-
Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells-potential role in carcinogen bioinactivation
-
Galijatovic A, Otake Y, Walle UK, and Walle T (2001) Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells-potential role in carcinogen bioinactivation. Pharm Res 19:374-379.
-
(2001)
Pharm Res
, vol.19
, pp. 374-379
-
-
Galijatovic, A.1
Otake, Y.2
Walle, U.K.3
Walle, T.4
-
10
-
-
0036304427
-
Current perspectives on the clinical experience, pharmacology and continued development of the camptothecins
-
Garcia-Carbonero R and Supko JG (2002) Current perspectives on the clinical experience, pharmacology and continued development of the camptothecins. Clin Cancer Res 8:641-661.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 641-661
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
-
11
-
-
0034966656
-
Thirteen UDPglucuronosyltransferase genes we encoded at the human UGT1 gene complex locus
-
Gong QH, Cho JW, Huang T, Potter C, Gholami N, Basu NK, Kubota S, Carvalho S, Pennington MW, Owens IS, and Popescu NC (2001) Thirteen UDPglucuronosyltransferase genes we encoded at the human UGT1 gene complex locus. Pharmacogenetics 11:357-368.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 357-368
-
-
Gong, Q.H.1
Cho, J.W.2
Huang, T.3
Potter, C.4
Gholami, N.5
Basu, N.K.6
Kubota, S.7
Carvalho, S.8
Pennington, M.W.9
Owens, I.S.10
Popescu, N.C.11
-
12
-
-
0033789766
-
Structural heterogeneity at the UDP-glucuronosyltransferase 1A locus: Functional consequences of three novel missense mutations in the human UGT1A7 gene
-
Guillemette C, Ritter JK, Auyeung DJ, Kessler FK, and Housman DE (2000) Structural heterogeneity at the UDP-glucuronosyltransferase 1A locus: functional consequences of three novel missense mutations in the human UGT1A7 gene. Pharmacogenetics 10:629-644.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 629-644
-
-
Guillemette, C.1
Ritter, J.K.2
Auyeung, D.J.3
Kessler, F.K.4
Housman, D.E.5
-
13
-
-
0035720744
-
Role of UGT1A1 mutation in fasting hyperbilirubinemia
-
Ishihara T, Kaita M, Takeuchi K, Gabazza EC, Tanaka Y, Higuchi K, Ikoma J, Watanabe S, Sato H, and Adachi Y (2001) Role of UGT1A1 mutation in fasting hyperbilirubinemia. J Gastroenterol Hepatol 16:678-682.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, pp. 678-682
-
-
Ishihara, T.1
Kaita, M.2
Takeuchi, K.3
Gabazza, E.C.4
Tanaka, Y.5
Higuchi, K.6
Ikoma, J.7
Watanabe, S.8
Sato, H.9
Adachi, Y.10
-
14
-
-
0032519431
-
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
-
Iyer L, King CD, Whitington PF, Green MD, Roy SK, Tephly TR, Coffman BL, and Ratain MJ (1998) Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest 101:847-854.
-
(1998)
J Clin Invest
, vol.101
, pp. 847-854
-
-
Iyer, L.1
King, C.D.2
Whitington, P.F.3
Green, M.D.4
Roy, S.K.5
Tephly, T.R.6
Coffman, B.L.7
Ratain, M.J.8
-
15
-
-
0031714683
-
Clinical pharmacology of camptothecins
-
Iyer L and Ratain MJ (1998) Clinical pharmacology of camptothecins. Cancer Chemother Pharmacol 42 Suppl:S31-S43.
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, Issue.SUPPL.
-
-
Iyer, L.1
Ratain, M.J.2
-
16
-
-
0033799997
-
Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyl transferase (UGT1A1) causing Crigler-Nejjar and Gilbert syndromes: Correlation of genotype to phenotype
-
Kadakol A, Ghosh SS, Sappal BS, Sharma G, Chowdhury JR, and Chowdhury NR (2000) Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyl transferase (UGT1A1) causing Crigler-Nejjar and Gilbert syndromes: correlation of genotype to phenotype. Hum Mutat 16:297-306.
-
(2000)
Hum Mutat
, vol.16
, pp. 297-306
-
-
Kadakol, A.1
Ghosh, S.S.2
Sappal, B.S.3
Sharma, G.4
Chowdhury, J.R.5
Chowdhury, N.R.6
-
17
-
-
0035199379
-
Cisplatin and irinotecan (CPT-11) as second line treatment in patients with advanced non-small cell lung cancer
-
Kakolyris S, Kouroussis C, Souglakos J, Agelaki S, Kalbakis K, Vardakis N, Vamvakas L, and Georgoulias V (2001) Cisplatin and irinotecan (CPT-11) as second line treatment in patients with advanced non-small cell lung cancer. Lung Cancer 34 Suppl 4:71-76.
-
(2001)
Lung Cancer 34 Suppl
, vol.4
, pp. 71-76
-
-
Kakolyris, S.1
Kouroussis, C.2
Souglakos, J.3
Agelaki, S.4
Kalbakis, K.5
Vardakis, N.6
Vamvakas, L.7
Georgoulias, V.8
-
18
-
-
0025996996
-
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
-
Kawato Y, Aonuma M, Hirota Y, Kuga H, and Sato K (1991) Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 51:4187-4191.
-
(1991)
Cancer Res
, vol.51
, pp. 4187-4191
-
-
Kawato, Y.1
Aonuma, M.2
Hirota, Y.3
Kuga, H.4
Sato, K.5
-
19
-
-
0034901949
-
Modulation of irinotecan-induced diarrhea by cotreatment with neomycin in cancer patients
-
Kehrer DF, Sparreboom A, Verweij J, de Bruijn P, Nierop CA, van de SJ, Ruijgrok EJ and de Jonge MJ (2001) Modulation of irinotecan-induced diarrhea by cotreatment with neomycin in cancer patients. Clin Cancer Res 7:1136-1141.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1136-1141
-
-
Kehrer, D.F.1
Sparreboom, A.2
Verweij, J.3
De Bruijn, P.4
Nierop, C.A.5
Van de, S.J.6
Ruijgrok, E.J.7
De Jonge, M.J.8
-
20
-
-
0032833129
-
pH-Dependent uptake of irinotecan and its active metabolite, SN-38, by intestinal cells
-
Kobayashi IC Bouscarel B, Matsuzaki Y, Ceryak S, Kudoh S, and Fromm H (1999) pH-Dependent uptake of irinotecan and its active metabolite, SN-38, by intestinal cells. Int J Cancer 83:491-496.
-
(1999)
Int J Cancer
, vol.83
, pp. 491-496
-
-
Kobayashi, I.C.1
Bouscarel, B.2
Matsuzaki, Y.3
Ceryak, S.4
Kudoh, S.5
Fromm, H.6
-
21
-
-
0032767352
-
UDP-Glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: Relationships to serum bilirubin concentrations
-
Lampe JW, Bigler J, Horner NK and Potter JD (1999) UDP-Glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations. Pharmacogenetics 9:341-349.
-
(1999)
Pharmacogenetics
, vol.9
, pp. 341-349
-
-
Lampe, J.W.1
Bigler, J.2
Horner, N.K.3
Potter, J.D.4
-
22
-
-
0002051568
-
The UDP glucuronoslytransferase multigene family
-
(Hodgson E, Bend JR, and Philpot RM eds), Taxicology Cummunications, Inc., Raleigh, NC
-
Mackenzie PI (1995) The UDP glucuronoslytransferase multigene family, in Reviews in Biochemical Toxicology (Hodgson E, Bend JR, and Philpot RM eds) pp 29-72, Taxicology Cummunications, Inc., Raleigh, NC.
-
(1995)
Reviews in Biochemical Toxicology
, pp. 29-72
-
-
Mackenzie, P.I.1
-
23
-
-
0033760290
-
Polymorphisms in UDP glucuronosyltransferase genes: Functional consequences and clinical relevance
-
Mackenzie, PI, Miners JO, and McKinnon RA (2000) Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance. Clin Chem Lab Med 38:889-892.
-
(2000)
Clin Chem Lab Med
, vol.38
, pp. 889-892
-
-
Mackenzie, P.I.1
Miners, J.O.2
McKinnon, R.A.3
-
24
-
-
8544224973
-
The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, et al. (1997) The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7:255-269.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255-269
-
-
Mackenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
Fournel-Gigleux, S.7
Green, M.8
Hum, D.W.9
Iyanagi, T.10
-
25
-
-
0034892379
-
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11)
-
Mathijssen RH, van Alphen RJ, Verweij J, Loos WJ, Nooter K, Stoter G, and Sparreboom A (2001) Clinical pharmacokinetics and metabolism of irinotecan (CPT-11). Clin Cancer Res 7:2182-2194.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2182-2194
-
-
Mathijssen, R.H.1
Van Alphen, R.J.2
Verweij, J.3
Loos, W.J.4
Nooter, K.5
Stoter, G.6
Sparreboom, A.7
-
26
-
-
0033813050
-
Insights into the pharmacokinetics and pharmacodynamics irinotecan
-
Ratain MJ (2000) Insights into the pharmacokinetics and pharmacodynamics irinotecan. Clin Cnncer Res 6:3393-3394.
-
(2000)
Clin Cnncer Res
, vol.6
, pp. 3393-3394
-
-
Ratain, M.J.1
-
27
-
-
0026701911
-
A Novel complex locus UGT1 encodes human bilirubin, phenol and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini
-
Ritter JK Chen F, Sheen YY, Tran HM, Kimura S, Yeatman MT, and Owens IS (1992) A Novel complex locus UGT1 encodes human bilirubin, phenol and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J Biol Chem 267:3257-3261.
-
(1992)
J Biol Chem
, vol.267
, pp. 3257-3261
-
-
Ritter, J.K.1
Chen, F.2
Sheen, Y.Y.3
Tran, H.M.4
Kimura, S.5
Yeatman, M.T.6
Owens, I.S.7
-
28
-
-
0028813952
-
A pharmacokinetic MJ pharmacodynamic analysis of CPT-11 and its active metabolite SN-38
-
Sasaki Y, Hakusui H, Mizuno S, Morita M, Miya T, Eguchi K, Shinkai T, Tamura T, Ohe Y, and Saijo N (1995) A pharmacokinetic MJ pharmacodynamic analysis of CPT-11 and its active metabolite SN-38. Jpn J Cancer Res 86:101-110.
-
(1995)
Jpn J Cancer Res
, vol.86
, pp. 101-110
-
-
Sasaki, Y.1
Hakusui, H.2
Mizuno, S.3
Morita, M.4
Miya, T.5
Eguchi, K.6
Shinkai, T.7
Tamura, T.8
Ohe, Y.9
Saijo, N.10
-
29
-
-
0028364014
-
Metabolic activation of CPT-11,7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase
-
Satoh, T, Hosokawa M, Atsumi R, Suzuki W, Hakusui H, and Nagai E (1994) Metabolic activation of CPT-11,7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase. Biol Pharm Bull 17:662-664.
-
(1994)
Biol Pharm Bull
, vol.17
, pp. 662-664
-
-
Satoh, T.1
Hosokawa, M.2
Atsumi, R.3
Suzuki, W.4
Hakusui, H.5
Nagai, E.6
-
30
-
-
0034038190
-
14C]CPT-11 in cancer patients
-
14C]CPT-11 in cancer patients. Drug Metab Dispos 28:423-433.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 423-433
-
-
Slatter, J.G.1
Schaaf, L.J.2
Sams, J.P.3
Feenstra, K.L.4
Johnson, M.G.5
Bombardt, P.A.6
Cathcart, K.S.7
Verburg, M.T.8
Pearson, L.K.9
Compton, L.D.10
-
31
-
-
0030863434
-
Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions
-
Slatter JG, Su P, Sams JP, Schaaf LJ, and Wienkers LC (1997) Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions. Drug Metab Dispos 25:1157-1164.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 1157-1164
-
-
Slatter, J.G.1
Su, P.2
Sams, J.P.3
Schaaf, L.J.4
Wienkers, L.C.5
-
32
-
-
0034680792
-
Polymorphic gene expression and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine
-
Strassburg CP, Kneip S, Topp J, Obermayer-Straub P, Barut A, Tukey RH, and Manns MP (2000) Polymorphic gene expression and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine. J Biol Chem 46:36164-36171.
-
(2000)
J Biol Chem
, vol.46
, pp. 36164-36171
-
-
Strassburg, C.P.1
Kneip, S.2
Topp, J.3
Obermayer-Straub, P.4
Barut, A.5
Tukey, R.H.6
Manns, M.P.7
-
33
-
-
0032502764
-
Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8
-
Strassburg CP, Manns MP, and Tukey RH (1998a) Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8. J Biol Chem 273:8719-8726.
-
(1998)
J Biol Chem
, vol.273
, pp. 8719-8726
-
-
Strassburg, C.P.1
Manns, M.P.2
Tukey, R.H.3
-
34
-
-
0031756678
-
Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium
-
Strassburg CP, Nguyen N, Manns MP, and Tukey RH (1998b) Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium. Mol Pharmacol 54:647-654.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 647-654
-
-
Strassburg, C.P.1
Nguyen, N.2
Manns, M.P.3
Tukey, R.H.4
-
36
-
-
0036101804
-
Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 in colorectal cancer
-
Strassburg CP, Vogel A, Kneip S, Tukey RH, and Manns M (2002) Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 in colorectal cancer. Gut 6:851-856.
-
(2002)
Gut
, vol.6
, pp. 851-856
-
-
Strassburg, C.P.1
Vogel, A.2
Kneip, S.3
Tukey, R.H.4
Manns, M.5
-
37
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression and disease
-
Tukey RH and Strassburg CP (2000) Human UDP-glucuronosyltransferases: metabolism, expression and disease. Annu Rev Pharmacol Toxicol 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
38
-
-
0035115599
-
Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract
-
Tukey RH and Strassburg CP (2001) Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract. Mol Pharmacol 59:405-414.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 405-414
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
39
-
-
0036159498
-
Irinotecan (CPT-11) in combination with infusional 5-fluorouracil and leucovorin (De Gramont Regimen) as first-line treatment in patients with advanced colorectal cancer: A multicenter phase II study
-
Vamvakas L, Kakolyris S, Kouroussis C, Kandilis K, Mavroudis D, Ziras N, Androulakis N, Kalbakis K, Sarra E, Souglakos J, et al. (2002) Irinotecan (CPT-11) in combination with infusional 5-fluorouracil and leucovorin (De Gramont Regimen) as first-line treatment in patients with advanced colorectal cancer: a multicenter phase II study. Am J Clin Oncol 25:65-70.
-
(2002)
Am J Clin Oncol
, vol.25
, pp. 65-70
-
-
Vamvakas, L.1
Kakolyris, S.2
Kouroussis, C.3
Kandilis, K.4
Mavroudis, D.5
Ziras, N.6
Androulakis, N.7
Kalbakis, K.8
Sarra, E.9
Souglakos, J.10
-
40
-
-
0034765595
-
Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene
-
Vogel A, Kneip S, Barut A, Ehmer U, Tukey RH, Manns MP, and Strassburg CP (2001) Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology 121:1136-1144.
-
(2001)
Gastroenterology
, vol.121
, pp. 1136-1144
-
-
Vogel, A.1
Kneip, S.2
Barut, A.3
Ehmer, U.4
Tukey, R.H.5
Manns, M.P.6
Strassburg, C.P.7
-
41
-
-
0033051339
-
Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2
-
Walle UK, Galijatovic A, and Walle T (1999) Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2. Biochem Pharmacol 58:431-438.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 431-438
-
-
Walle, U.K.1
Galijatovic, A.2
Walle, T.3
-
42
-
-
0034941111
-
Active transepithelial transport of irinotecan (CPT-11) and its metabolites by human intestinal Caco-2 cells
-
Yamamoto W, Verweij J, de Bruijn P, de Jonge MJ, Takano H, Nishiyama M, Kurihara M, and Sparreboom A (2001) Active transepithelial transport of irinotecan (CPT-11) and its metabolites by human intestinal Caco-2 cells. Anticancer Drugs 12:419-432.
-
(2001)
Anticancer Drugs
, vol.12
, pp. 419-432
-
-
Yamamoto, W.1
Verweij, J.2
De Bruijn, P.3
De Jonge, M.J.4
Takano, H.5
Nishiyama, M.6
Kurihara, M.7
Sparreboom, A.8
-
43
-
-
0035913673
-
Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk
-
Zheng Z, Park JY, Guillemette C, Schantz SP, and Lazarus P (2001) Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk. J Natl Cancer Inst 93:1411-1418.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1411-1418
-
-
Zheng, Z.1
Park, J.Y.2
Guillemette, C.3
Schantz, S.P.4
Lazarus, P.5
|