Characterization of 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl] quinoline N-glucuronidation by in vitro and in vivo approaches

Drug Metabolism and Disposition

Volumn 29, Issue 3, 2001, Pages 289-295

  Stevens, J C ^a   Fayer, J L ^a   Cassidy, K C ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 [2 (5 TETRAZOLYLMETHYL)BENZYLOXY]PHENOXYMETHYL]QUINOLINE; DRUG METABOLITE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; IMIPRAMINE; NARINGENIN; SCOPOLETIN;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG GLUCURONIDATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; LIVER MICROSOME; MALE; MONKEY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PH; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ANIMALS; BIOLOGICAL AVAILABILITY; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; FLAVANONES; FLAVONOIDS; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HAPLORHINI; HEPATOCYTES; HUMANS; HYDROGEN-ION CONCENTRATION; IMIPRAMINE; ISOENZYMES; JEJUNUM; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROSOMES, LIVER; QUINOLINES; RATS; SCOPOLETIN; SUBSTRATE SPECIFICITY; TETRAZOLES;

ANIMALIA;

EID: 0035111915     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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