Catalytic antioxidants: A radical approach to new therapeutics

Drug Discovery Today

Volumn 9, Issue 13, 2004, Pages 557-566

  Day, Brian J ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Biochemistry; catalase; Chemical Biology; Drug Discovery; hydrogen peroxide; macrocyclics; oxidative stress; peroxynitrite; Pharmaceutical Science; porphyrins; reactive oxygen species; salens; Superoxide dismutase

Indexed keywords

AEOL 10110; AEOL 10113; AEOL 10123; AEOL 10150; AEOL 10158; AEOL 10170; AEOL 10201; AEOL 10216; AEOL 10217; AEROL 10201; ANTIOXIDANT; EUK 189; EUK 207; M 40401; MACROCYCLIC COMPOUND; MANGANESE; MANGANESE N,N' ETHYLENEBIS(3 METHOXYSALICYLIDENEAMINE); MANGANESE SALEN CHLORIDE; MANGANESEDICHLORO(3,10,13,20,26 PENTAAZATETRACYCLO[20.3.1.0(4,9).0(14,19)] 1(26),22(23),24 HEXACOSATRIENE); METALLOPROTEIN; PORPHYRIN; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ACUTE RESPIRATORY TRACT DISEASE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTHRITIS; ASTHMA; BLOOD VESSEL; CHELATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; COLITIS; CYTOTOXICITY; DEGENERATIVE DISEASE; DEMENTIA; DIABETES MELLITUS; DRUG EFFICACY; ENZYME ACTIVITY; EPILEPSY; HEART INFARCTION; INFLAMMATION; ISCHEMIA; LIVER FAILURE; LUNG DYSPLASIA; LUNG FIBROSIS; MIGRAINE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PAIN; PLEURISY; REPERFUSION; REVIEW; SHOCK; SPINAL CORD INJURY; STROKE; TISSUE INJURY; TRANSPLANTATION;

ANIMALS; ANTIOXIDANTS; CATALYSIS; HUMANS; REACTIVE OXYGEN SPECIES;

EID: 2942623947     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(04)03139-3     Document Type: Review

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