Superoxide dismutase mimetics with catalase activity reduce the organ injury in hemorrhagic shock

Shock

Volumn 18, Issue 3, 2002, Pages 230-235

  Izumi, Maya ^a   McDonald, Michelle C ^a   Sharpe, Martyn A ^b   Chatterjee, Prabal K ^a   Thiemermann, Christoph ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Catalase; EUK 134; EUK 8; Multiple organ failure; Oxygen radicals; Superoxide anions; Superoxide dismutase

Indexed keywords

EID: 0038727119     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200209000-00005     Document Type: Article

References (43)

1. Redl H, Gasser H, Schlag G, Marzi I: Involvement of oxygen radicals in shock related cell injury. Br Med Bull 49:556-565, 1993.
2. Simons RK, Maier RV, Lennards ES: Neutrophil function in a rat model of endotoxin-induced lung injury. Arch Surg 122:197-203, 1987.
3. Vespasiano MC, Lewandoski JR, Zimmerman JJ: Longitudinal analysis of neutrophil superoxide anion generation in patients with septic shock. Crit Care Med 21:666-672, 1993.
4. Brackett DJ, Lai EK, Lerner MR, Wilson MF, McCay PB: Spin trapping of free radicals produced "in vivo" in heart and liver during endotoxemia. Free Rad Res Commun 7:315-324, 1989.
5. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA: Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87:1620-1624, 1990.
6. Zingarelli B, Day BJ, Crapo JD, Salzman AL, Szabo C: The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock. Br J Pharmacol 120:259-267, 1997.
7. Szabo C, Salzman AL, Ischiropoulos H: Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury. FEBS Lett 372:229-232, 1995.
8. Fleckenstein AE, Smith SL, Linseman KL, Beuving LF, Hall ED: Comparison of the efficacy of mechanistically different antioxidants in the rat hemorrhagic shock model. Circ Shock 35:223-230, 1991.
9. Hamano K, Tsuboi H, Seyama A, Esato K: Shock-reinfusion injury to the central organs and the effect of free radical scavengers in the rat. Surg Today 23:891-896, 1993.
10. Baldwin SR, Simon RH, Grum CM, Ketai LH, Boxer LA, Devall LJ: Oxidant activity in expired breath of patients with adult respiratory distress syndrome. Lancet 1:11-14, 1986.
11. Sznajder JI, Fraiman A, Hall JB, Sanders W, Schmidt G, Crawford G, Nahum A, Factor P, Wood LD: Increased hydrogen peroxide in the expired breath of patients with acute hypoxemic respiratory failure. Chest 96:606-612, 1989.
12. Fan J, Marshall JC, Jimenez M, Shek PN, Zagorski J, Rotstein OD: Hemorrhagic shock primes for increased expression of cytokine-induced neutrophil chemoattractant in the lung: role in pulmonary inflammation following lipopolysaccharide. J Immunol 161:440-447, 1998.
13. Mannion D, Fitzpatrick GJ, Feeley M: Role of xanthine oxidase inhibition in survival from hemorrhagic shock. Circ Shock 42:39-43, 1994.
14. Daughters K, Waxman K, Gassel A, Zommer S: Anti-oxidant treatment for shock: vitamin E but not vitamin C improves survival. Am Surg 62:789-792, 1996.
15. Allan G, Cambridge D, Lee-Tsang-Tang L, Van Way CW, Whiting MV: The protective action of allopurinol in an experimental model of haemorrhagic shock and reperfusion. Br J Pharmacol 89:149-155, 1986.
16. Flynn WJ Jr, Pilati D, Hoover EL: Xanthine oxidase inhibition prevents mesenteric blood flow deficits after resuscitated hemorrhagic shock by preserving endothelial function. J Surg Res 68:175-180, 1997.
17. Bond RF, Haines GA, Johnson G: The effect of allopurinol and catalase on cardiovascular hemodynamics during hemorrhagic shock. Circ Shock 25:139-151, 1988.
18. Sanan S, Sharma G, Malhotra R, Sanan DP, Jain P, Vadhera P: Protection by desferrioxamine against histopathological changes of the liver in the post-oligemic phase of clinical haemorrhagic shock in dogs: correlation with improved survival rate and recovery. Free Rad Res Commun 6:29-38, 1989.
19. Simon HM, Scalea T, Paskanik A, Yang B: Superoxide dismutase (SOD) prevents hypotension after hemorrhagic shock and aortic cross clamping. Am J Med Sci 312:155-159, 1996.
20. Rhee P, Waxman K, Clark L, Tominaga G, Soliman MH: Superoxide dismutase polyethylene glycol improves survival in hemorrhagic shock. Am Surg 57:747-750, 1991.
21. Lee ES, Greenburg AG, Maffuid PW, Melcher ED, Velky TS: Superoxide radicals and hemorrhagic shock: are intravascular radicals associated with mortality? Surg Res 42:1-6, 1987.
22. Redl H, Lieners C, Bahrami S, Schlag G, van Bebber IP, Goris RJ: SOD in rat models of shock and organ failure. Adv Exp Med Biol 264:17-27, 1990.
23. Goode HF, Webster NR: Free radicals and antioxidants in sepsis. Crit Care Med 21:1770-1776, 1993.
24. Yim MB, Chock PB, Stadtman ER: Copper, zinc superoxide dismutase catalyses hydroxyl radical production from hydrogen peroxide. Proc Natl Acad Sci USA 87:5006-5010, 1990.
25. Fridovich I: Superoxide radical and superoxide dismutases. Annu Rev Biochem 64:97-112, 1995.
26. Baker K, Marcus KB, Huffman K, Kruk H, Malfroy B, Doctrow SR: Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury. J Pharmacol Exp Ther 284:215-221, 1998.
27. Gianello P, Saliez A, Bufkens X, Pettinger R, Misseleyn D, Hori S, Malfroy B: EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. Transplantation 62:1664-1666, 1996.
28. Pucheu S, Boucher F, Sulpice T, Tresallet N, Bonhomme Y, Malfroy B, de Leiris J: EUK-8 a synthetic catalytic scavenger of reactive oxygen species protects isolated, iron-overloaded rat heart from functional and structural damage induced by ischemia-reperfusion. Cardiovasc Drugs Ther 10:331-339, 1996.
29. Mota-Filipe H, McDonald MC, Cuzzocrea S, Thiemermann C: A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock. Shock, 12:255-261, 1999.
30. Laight DW, Andrews TJ, Haj-Yehia AI: Microassay of superoxide anion scavenging activity in vitro. Environ Tox Pharm 3:65-68, 1997.
31. Leach M, Frank S, Olbrich A, Pfeilschifter J, Thiemermann C: Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: effects of the superoxide anion radical scavenger, tempol, on organ injury. Br J Pharmacol 125:817-825, 1998.
32. Sledzinski Z, Wozniak M, Antosiewicz J, Lezoche E, Familiari M, Berloli E, Creci L, Brunelli A, Mazera N, Wajda Z: Protective effect of 4-hydroxy-TEMPO, a low molecular weight superoxide dismutase mimic, on free radical toxicity in experimental pancreatitis. Int J Pancreatol 18:153-160, 1995.
33. McDonald MC, Zacharowski K, Bowes J, Cuzzocrea S, Thiemermann C: Tempol reduces infarct size in rodent models of regional myocardial ischaemia and reperfusion. Free Rad Biol Med 27:493-503, 1999.
34. Szabo C, Virag L, Cuzzocrea S, Scott GS, Hake P, O'Conner MP, Zingarelli B, Salzman A, Kun E: Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase. Proc Natl Acad Sci USA 95:3867-3872, 1998.
35. Zingarelli B, Virag L, Szabo A, Cuzzocrea S, Salzman AL, Szabo C: Oxidation, tyrosine nitration and cytostasis induction in the absence of inducible nitric oxide synthase. Int J Mol Med 1:787-795, 1998.
36. Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B, van der Vliet A: Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391:393-397, 1998.
37. Malfroy B, Doctrow SR, Orr PL, Tocco G, Fedoseyeva EV, Benichou G: Prevention and suppression of autoimmune encephalitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites. Cell Immunol 177:62-68, 1997.
38. Jung C, Rong Y, Doctrow S, Baudry M, Malfroy B, Xa Z: Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model. Neurosci Lett 304:157-160, 2001.
39. Gonzalez PK, Zhuang J, Doctrow SR, Malfroy B, Benson PF, Menconi MJ, Fink MP: Role of oxidant stress in the adult respiratory distress syndrome: evaluation of novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury. Shock 1:S23-S26, 1996.
40. Bruce AJ, Malfroy B, Baudry M: Beta-amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc Natl Acad Sci USA 93:2312-2316, 1996.
41. Rong Y, Doctrow SR, Tocco G, Baudrey M: EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology. Proc Natl Acad Sci USA 96:9897-9902, 1999.
42. Millar CG, Thiemermann C: Intrarenal haemodynamics and renal dysfunction in endotoxaemia: effects of nitric oxide synthase inhibition. Br J Pharmacol 121:1824-1830, 1997.
43. Wray GM, Millar CG, Hinds CJ, Thiemermann C: Selective inhibition of the activity of inducible nitric oxide synthase prevents the circulatory failure, but not the organ injury/dysfunction, caused by endotoxin. Shock 9:329-335, 1998.