메뉴 건너뛰기




Volumn 103, Issue 12, 2004, Pages 4622-4629

NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D2; HYBRID PROTEIN; NUCLEOPHOSMIN ANAPLASTIC LYMPHOMA KINASE; PHOSPHOINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN; PROTEIN FOXO3A; PROTEIN KINASE B; PROTEIN P27; PROTEIN P27 KLP1; UNCLASSIFIED DRUG;

EID: 2942618200     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-03-0820     Document Type: Article
Times cited : (85)

References (45)
  • 1
    • 0036731704 scopus 로고    scopus 로고
    • Molecular biology of anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma
    • Kutok JL, Aster JC. Molecular biology of anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma. J Clin Oncol. 2002;20:3691-3702.
    • (2002) J Clin Oncol , vol.20 , pp. 3691-3702
    • Kutok, J.L.1    Aster, J.C.2
  • 2
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001;344:1038-1042.
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 3
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 4
    • 0029648292 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science. 1995;267:316-317.
    • (1995) Science , vol.267 , pp. 316-317
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 5
    • 0029981836 scopus 로고    scopus 로고
    • Occurrence of the t(2;5)(p23;q35) in non-Hodgkin's lymphoma
    • Weisenburger DD, Gordon BG, Vose JM, et al. Occurrence of the t(2;5)(p23;q35) in non-Hodgkin's lymphoma. Blood. 1996;87:3860-3868.
    • (1996) Blood , vol.87 , pp. 3860-3868
    • Weisenburger, D.D.1    Gordon, B.G.2    Vose, J.M.3
  • 6
    • 0031008896 scopus 로고    scopus 로고
    • ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
    • Morris SW, Naeve C, Mathew P, et al. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene. 1997;14:2175-2188.
    • (1997) Oncogene , vol.14 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3
  • 7
    • 0024966024 scopus 로고
    • Major nucleolar proteins shuttle between nucleus and cytoplasm
    • Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell. 1989;56:379-390.
    • (1989) Cell , vol.56 , pp. 379-390
    • Borer, R.A.1    Lehner, C.F.2    Eppenberger, H.M.3    Nigg, E.A.4
  • 8
    • 0024595908 scopus 로고
    • Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth
    • Chan WY, Liu QR, Borjigin J, et al. Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth. Biochemistry. 1989;28:1033-1039.
    • (1989) Biochemistry , vol.28 , pp. 1033-1039
    • Chan, W.Y.1    Liu, Q.R.2    Borjigin, J.3
  • 9
    • 0034730321 scopus 로고    scopus 로고
    • Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication
    • Okuda M, Horn HF, Tarapore P, et al. Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication. Cell. 2000;103:127-140.
    • (2000) Cell , vol.103 , pp. 127-140
    • Okuda, M.1    Horn, H.F.2    Tarapore, P.3
  • 10
    • 0031035052 scopus 로고    scopus 로고
    • Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system
    • Iwahara T, Fujimoto J, Wen D, et al. Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene. 1997;14:439-449.
    • (1997) Oncogene , vol.14 , pp. 439-449
    • Iwahara, T.1    Fujimoto, J.2    Wen, D.3
  • 11
    • 0031755958 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity
    • Bai RY, Dieter P, Peschel C, Morris SW, Duyster J. Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity. Mol Cell Biol. 1998;18:6951-6961.
    • (1998) Mol Cell Biol , vol.18 , pp. 6951-6961
    • Bai, R.Y.1    Dieter, P.2    Peschel, C.3    Morris, S.W.4    Duyster, J.5
  • 12
    • 0034672140 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway
    • Bai RY, Ouyang T, Miething C, Morris SW, Peschel C, Duyster J. Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway. Blood. 2000;96:4319-4327.
    • (2000) Blood , vol.96 , pp. 4319-4327
    • Bai, R.Y.1    Ouyang, T.2    Miething, C.3    Morris, S.W.4    Peschel, C.5    Duyster, J.6
  • 13
    • 0030809095 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice
    • Kuefer MU, Look AT, Pulford K, et al. Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice. Blood. 1997;90:2901-2910.
    • (1997) Blood , vol.90 , pp. 2901-2910
    • Kuefer, M.U.1    Look, A.T.2    Pulford, K.3
  • 14
    • 0037372285 scopus 로고    scopus 로고
    • NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors
    • Chiarle R, Gong JZ, Guasparri I, et al. NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood. 2003;101:1919-1927.
    • (2003) Blood , vol.101 , pp. 1919-1927
    • Chiarle, R.1    Gong, J.Z.2    Guasparri, I.3
  • 15
    • 0036134884 scopus 로고    scopus 로고
    • Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
    • Zhang Q, Raghunath PN, Xue L, et al. Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma. J Immunol. 2002;168:466-474.
    • (2002) J Immunol , vol.168 , pp. 466-474
    • Zhang, Q.1    Raghunath, P.N.2    Xue, L.3
  • 16
    • 0035419348 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 5 in nucleophosmin/anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells
    • Nieborowska-Skorska M, Slupianek A, Xue L, et al. Role of signal transducer and activator of transcription 5 in nucleophosmin/anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Cancer Res. 2001;61:6517-6523.
    • (2001) Cancer Res , vol.61 , pp. 6517-6523
    • Nieborowska-Skorska, M.1    Slupianek, A.2    Xue, L.3
  • 17
    • 85047699293 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
    • Zamo A, Chiarle R, Piva R, et al. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene. 2002;21:1038-1047.
    • (2002) Oncogene , vol.21 , pp. 1038-1047
    • Zamo, A.1    Chiarle, R.2    Piva, R.3
  • 18
    • 0035266314 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis
    • Slupianek A, Nieborowska-Skorska M, Hoser G, et al. Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis. Cancer Res. 2001;61:2194-2199.
    • (2001) Cancer Res , vol.61 , pp. 2194-2199
    • Slupianek, A.1    Nieborowska-Skorska, M.2    Hoser, G.3
  • 19
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 1997;91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3
  • 20
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science. 1997;278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 21
    • 0032515027 scopus 로고    scopus 로고
    • Regulation of cell death protease caspase-9 by phosphorylation
    • Cardone MH, Roy N, Stennicke HR, et al. Regulation of cell death protease caspase-9 by phosphorylation. Science. 1998;282:1318-1321.
    • (1998) Science , vol.282 , pp. 1318-1321
    • Cardone, M.H.1    Roy, N.2    Stennicke, H.R.3
  • 23
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 1999;96:857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3
  • 25
    • 13044315956 scopus 로고    scopus 로고
    • Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B
    • Takaishi H, Konishi H, Matsuzaki H, et al. Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B. Proc Natl Acad Sci U S A. 1999;96:11836-11841.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 11836-11841
    • Takaishi, H.1    Konishi, H.2    Matsuzaki, H.3
  • 26
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg S, Paradis S, Gottlieb S, et al. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature. 1997;389:994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3
  • 27
    • 0036629251 scopus 로고    scopus 로고
    • Cell cycle and death control: Long live Forkheads
    • Burgering BM, Kops GJ. Cell cycle and death control: long live Forkheads. Trends Biochem Sci. 2002;27:352-360.
    • (2002) Trends Biochem Sci , vol.27 , pp. 352-360
    • Burgering, B.M.1    Kops, G.J.2
  • 28
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol. 2001;21:952-965.
    • (2001) Mol Cell Biol , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5    Greenberg, M.E.6
  • 29
    • 0038362751 scopus 로고    scopus 로고
    • Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
    • Plas DR, Thompson CB. Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J Biol Chem. 2003;278:12361-12366.
    • (2003) J Biol Chem , vol.278 , pp. 12361-12366
    • Plas, D.R.1    Thompson, C.B.2
  • 30
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol. 2000;10:1201-1204.
    • (2000) Curr Biol , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 31
    • 0037017396 scopus 로고    scopus 로고
    • FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
    • Dijkers PF, Birkenkamp KU, Lam EW, et al. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol. 2002;156:531-542.
    • (2002) J Cell Biol , vol.156 , pp. 531-542
    • Dijkers, P.F.1    Birkenkamp, K.U.2    Lam, E.W.3
  • 32
    • 0034459180 scopus 로고    scopus 로고
    • Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1)
    • Dijkers PF, Medema RH, Pals C, et al. Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). Mol Cell Biol. 2000;20:9138-9148.
    • (2000) Mol Cell Biol , vol.20 , pp. 9138-9148
    • Dijkers, P.F.1    Medema, R.H.2    Pals, C.3
  • 33
    • 0036120725 scopus 로고    scopus 로고
    • Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors
    • Kops GJ, Medema RH, Glassford J, et al. Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol Cell Biol. 2002;22:2025-2036.
    • (2002) Mol Cell Biol , vol.22 , pp. 2025-2036
    • Kops, G.J.1    Medema, R.H.2    Glassford, J.3
  • 34
    • 0036839685 scopus 로고    scopus 로고
    • Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
    • Schmidt M, de Mattos Fernandez S, van der Horst A, et al. Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol. 2002;22:7842-7852.
    • (2002) Mol Cell Biol , vol.22 , pp. 7842-7852
    • Schmidt, M.1    De Mattos Fernandez, S.2    Van Der Horst, A.3
  • 35
    • 0037134040 scopus 로고    scopus 로고
    • DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
    • Tran H, Brunet A, Grenier JM, et al. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science. 2002;296:530-534.
    • (2002) Science , vol.296 , pp. 530-534
    • Tran, H.1    Brunet, A.2    Grenier, J.M.3
  • 36
    • 0037136563 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    • Kops GJ, Dansen TB, Polderman PE, et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature. 2002;419:316-321.
    • (2002) Nature , vol.419 , pp. 316-321
    • Kops, G.J.1    Dansen, T.B.2    Polderman, P.E.3
  • 37
    • 85047695408 scopus 로고    scopus 로고
    • Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells
    • Mahmud DL, G-Amlak M, Deb DK, Platanias LC, Uddin S, Wickrema A. Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells. Oncogene. 2002;21:1556-1562.
    • (2002) Oncogene , vol.21 , pp. 1556-1562
    • Mahmud, D.L.1    G-Amlak, M.2    Deb, D.K.3    Platanias, L.C.4    Uddin, S.5    Wickrema, A.6
  • 38
    • 0032525270 scopus 로고    scopus 로고
    • Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression
    • Klucher KM, Lopez DV, Daley GQ. Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression. Blood. 1998;91:3927-3934.
    • (1998) Blood , vol.91 , pp. 3927-3934
    • Klucher, K.M.1    Lopez, D.V.2    Daley, G.Q.3
  • 39
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller J, Frantsve J, Aster J, et al. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 1998;17:5321-5333.
    • (1998) EMBO J , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3
  • 41
    • 0035839867 scopus 로고    scopus 로고
    • Translocations involving anaplastic lymphoma kinase (ALK)
    • Duyster J, Bai RY, Morris SW. Translocations involving anaplastic lymphoma kinase (ALK). Oncogene. 2001;20:5623-5637.
    • (2001) Oncogene , vol.20 , pp. 5623-5637
    • Duyster, J.1    Bai, R.Y.2    Morris, S.W.3
  • 42
    • 0036651790 scopus 로고    scopus 로고
    • A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
    • Ramaswamy S, Nakamura N, Sansal I, Bergeron L, Sellers WR. A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell. 2002;2:81-91.
    • (2002) Cancer Cell , vol.2 , pp. 81-91
    • Ramaswamy, S.1    Nakamura, N.2    Sansal, I.3    Bergeron, L.4    Sellers, W.R.5
  • 43
    • 0035918148 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
    • Cahill CM, Tzivion G, Nasrin N, et al. Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways. J Biol Chem. 2001;276:13402-13410.
    • (2001) J Biol Chem , vol.276 , pp. 13402-13410
    • Cahill, C.M.1    Tzivion, G.2    Nasrin, N.3
  • 44
    • 18444407158 scopus 로고    scopus 로고
    • Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor
    • Cools J, Wlodarska I, Somers R, et al. Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes Chromosomes Cancer. 2002;34:354-362.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 354-362
    • Cools, J.1    Wlodarska, I.2    Somers, R.3
  • 45
    • 0037134490 scopus 로고    scopus 로고
    • Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth
    • Powers C, Aigner A, Stoica GE, McDonnell K, Wellstein A. Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth. J Biol Chem. 2002;277:14153-14158.
    • (2002) J Biol Chem , vol.277 , pp. 14153-14158
    • Powers, C.1    Aigner, A.2    Stoica, G.E.3    McDonnell, K.4    Wellstein, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.