Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 13402-13410

  Cahill, Catherine M ^a   Tzivion, Guri ^a   Nasrin, Nargis ^a   Ogg, Scott ^a   Dore, Justin ^a   Ruvkun, Gary ^a   Alexander Bridges, Maria ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ENZYME INHIBITION; INSULIN; PROTEINS;

KINASES; PHOSPHORYLATION;

DNA;

2 MORPHOLINO 8 PHENYLCHROMONE; DNA; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN 14 3 3; PROTEIN KINASE B; SOMATOMEDIN BINDING PROTEIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG; AKT 1 PROTEIN, C ELEGANS; AKT-1 PROTEIN, C ELEGANS; AKT1 PROTEIN, HUMAN; CAENORHABDITIS ELEGANS PROTEIN; DAF 16 PROTEIN, C ELEGANS; DAF-16 PROTEIN, C ELEGANS; DNA BINDING PROTEIN; HYBRID PROTEIN; ONCOPROTEIN; PAR 5 PROTEIN, C ELEGANS; PAR-5 PROTEIN, C ELEGANS; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; TYROSINE 3 MONOOXYGENASE;

ARTICLE; BINDING SITE; CAENORHABDITIS ELEGANS; CELL STRAIN HEPG2; DNA RESPONSIVE ELEMENT; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; GENE ACTIVITY; GENE FUNCTION; HORMONE ACTION; IN VITRO STUDY; INSULIN RESPONSIVE ELEMENT; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CONSENSUS SEQUENCE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; MAMMAL; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 14-3-3 PROTEINS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CONSENSUS SEQUENCE; DNA; DNA-BINDING PROTEINS; HUMANS; MAMMALS; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TYROSINE 3-MONOOXYGENASE;

EID: 0035918148     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010042200     Document Type: Article

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