Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling

Development

Volumn 125, Issue 16, 1998, Pages 3123-3132

  Yang, Yingzi ^a   Guillot, Pascale ^b   Boyd, Yvonne ^b   Lyon, Mary F ^b   McMahon, Andrew P ^a  

^a HARVARD UNIVERSITY   (United States)

^b MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

Doublefoot mutant; Indian hedgehog; Limb patterning; Mouse; Polydactyly

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANTERIOR POSTERIOR AXIS; ARTICLE; CHROMOSOME 1; CHROMOSOME MAP; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FINGER; GENE ACTIVATION; GENE DISRUPTION; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; HAPLOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; IN SITU HYBRIDIZATION; LIMB BUD; LIMB DEVELOPMENT; MOUSE; MULTIGENE FAMILY; MUTANT; MUTATION; NONHUMAN; PHENOTYPE; POLYDACTYLY; PRIORITY JOURNAL;

ANIMALS; BONE MORPHOGENETIC PROTEINS; EMBRYONIC INDUCTION; EXTREMITIES; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; HOMOZYGOTE; IN SITU HYBRIDIZATION; MICE; MICE, INBRED STRAINS; MUTATION; POLYDACTYLY; PROTEINS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; ERINACEIDAE; VERTEBRATA;

EID: 0031696178     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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