Role of nuclear receptors in lung tumourigenesis

European Journal of Cancer

Volumn 41, Issue 16, 2005, Pages 2561-2568

  Nemenoff, Raphael A ^a   Winn, Robert A ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Estrogen; Lung cancer; Non small cell lung cancer; Nuclear receptors; Peroxisome proliferator activated receptors

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIESTROGEN; CELL NUCLEUS RECEPTOR; CIGLITAZONE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; ESTROGEN RECEPTOR; GEFITINIB; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TAMOXIFEN; TROGLITAZONE;

AMINO TERMINAL SEQUENCE; CANCER GROWTH; DRUG SENSITIVITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; HUMAN; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; SOMATIC MUTATION; TRANSCRIPTION INITIATION;

EID: 27544477377     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2005.08.015     Document Type: Article

References (72)

1. N.J. McKenna, and B.W. O'Malley Combinatorial control of gene expression by nuclear receptors and coregulators Cell 108 4 2002 465 474
2. S.T. Pearce, and V.C. Jordan The biological role of estrogen receptors alpha and beta in cancer Crit Rev Oncol Hematol 50 1 2004 3 22
3. K.M. Kerr Pulmonary preinvasive neoplasia J Clin Pathol 54 4 2001 257 271
4. G. Giaccone Oncogenes and antioncogenes in lung tumourigenesis Chest 109 Suppl. 5 1996 130S 134S
5. T. Mitsudomi, J. Viallet, and J.L. Mulshine Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines Oncogene 6 1991 1353 1362
6. A.M. Malkinson Molecular comparison of human and mouse pulmonary adenocarcinomas Exp Lung Res 24 4 1998 541 555
7. A.F. Gazdar, and D.P. Carbone The biology and molecular genetics of lung cancer 1994 Landes Austin (TX)
8. D.B. Weiner, J. Norderg, and R. Robinson Expression of the neu gene-encoded protein (p185neu) in human non-small cell carcinomas of the lung Cancer Res 50 1990 421 425
9. A. Bhattacharjee, W.G. Richards, and J. Staunton Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses Proc Natl Acad Sci USA 98 24 2001 13790 13795
10. M.E. Garber, O.G. Troyanskaya, and K. Schluens Diversity of gene expression in adenocarcinoma of the lung Proc Natl Acad Sci USA 98 24 2001 13784 13789
11. P.A.J. Bunn, D. Chan, and D.G. Dienhart Neuropeptide signal transduction in lung cancer: clinical implications of bradyknin sensitivity and overall heterogeneity Cancer Res 52 1992 24 31
12. G.D. Sorenson, O.S. Pettengill, and T. Brinck-Johnsen Hormone production by cultures of small-cell carcinoma of the lung Cancer 47 1981 1289 1296
13. J.G. Paez, P.A. Janne, and J.C. Lee EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 5676 2004 1497 1500
14. T.J. Lynch, D.W. Bell, and R. Sordella Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib N Engl J Med 350 21 2004 2129 2139
15. S. Kakiuchi, Y. Daigo, and N. Ishikawa Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839) Hum Mol Genet 2004
16. J. Berger, and D.E. Moller The mechanisms of action of PPARs Annu Rev Med 53 2002 409 435
17. M.E. Greene, B. Blumberg, and O.W. McBride Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping Gene Exp 4 4-5 1995 281 299
18. 2 metabolite binds peroxisome proliferator-activated receptorγ and promotes adipocyte differentiation Cell 83 1995 813 819
19. L. Nagy, P. Tontonoz, and J.G. Alvarez Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma Cell 93 2 1998 229 240
20. L.C. Bell-Parikh, T. Ide, and J.A. Lawson Biosynthesis of 15-deoxy-{Delta}12,14-PGJ2 and the ligation of PPAR{gamma J Clin Invest 112 6 2003 945 955
21. J.M. Lehmann, L.B. Moore, and T.A. Smith-Oliver An anti-diabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator- activated receptor gamma (PPAR gamma) J Biol Chem 270 22 1995 12953 12956
22. J.M. Lehmann, J.M. Lenhard, and B.B. Oliver Peroxisome proliferater-activated receptors α andγ are activated by indomethacin and other non-steroidal anti-inflammatory drugs J Biol Chem 272 1997 3406 3410
23. P. Tontonoz, R.A. Graves, and A.I. Budavari Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha Nucleic Acids Res 22 25 1994 5628 5634
24. Y. Barak, M.C. Nelson, and E.S. Ong PPAR gamma is required for placental, cardiac, and adipose tissue development Mol Cell 4 4 1999 585 595
25. E.D. Rosen, P. Sarraf, and A.E. Troy PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro Mol Cell 4 4 1999 611 617
26. T.E. Akiyama, S. Sakai, and G. Lambert Conditional disruption of the peroxisome proliferator-activated receptor {gamma} gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux Mol Cell Biol 22 8 2002 2607 2619
27. G.D. Demetri, C.D. Fletcher, and E. Mueller Induction of solid tumour differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma Proc Natl Acad Sci USA 96 7 1999 3951 3956
28. P. Sarraf, E. Mueller, and D. Jones Differentiation and reversal of malignant changes in colon cancer through PPARgamma Nat Med 4 9 1998 1046 1052
29. K.W. Kinzler, and B. Vogelstein Lessons from hereditary colorectal cancer Cell 87 1996 159 170
30. P. Sarraf, E. Mueller, and W.M. Smith Loss-of-function mutations in PPAR gamma associated with human colon cancer Mol Cell 3 6 1999 799 804
31. E. Saez, P. Tontonoz, and M.C. Nelson Activators of the nuclear receptor PPARgamma enhance colon polyp formation Nat Med 4 9 1998 1058 1061
32. A.M. Lefebvre, I. Chen, and P. Desreumaux Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumours in C57BL/6J-APCMin/+ mice Nat Med 4 9 1998 1053 1057
33. E. Mueller, P. Sarraf, and P. Tontonoz Terminal differentiation of human breast cancer through PPAR gamma Mol Cell 1 3 1998 465 470
34. E. Mueller, M. Smith, and P. Sarraf Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer Proc Natl Acad Sci USA 97 20 2000 10990 10995
35. E. Saez, J. Rosenfeld, and A. Livolsi PPAR{gamma} signalling exacerbates mammary gland tumour development Genes Dev 18 5 2004 528 540
36. T.-H. Chang, and E. Szabo Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor {gamma} in non-small cell lung cancer Cancer Res 60 4 2000 1129 1138
37. Y. Tsubouchi, H. Sano, and Y. Kawahito Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-γ agonists through induction of apoptosis Biochem Biophys Res Comm 270 2000 400 405
38. M. Wick, G. Hurteau, and C. Dessev Peroxisome proliferator-activated receptor-gamma is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth Mol Pharmacol 62 5 2002 1207 1214
39. T. Satoh, M. Toyoda, and H. Hoshino Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells Oncogene 21 14 2002 2171 2180
40. H. Sasaki, M. Tanahashi, and H. Yukiue Decreased perioxisome proliferator-activated receptor gamma gene expression was correlated with poor prognosis in patients with lung cancer Lung Cancer 36 1 2002 71 76
41. S. Han, N. Sidell, and P.B. Fisher Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells Clin Cancer Res 10 6 2004 1911 1919
42. S. Han, and J. Roman Suppression of prostaglandin E2 receptor subtype EP2 by PPARgamma ligands inhibits human lung carcinoma cell growth Biochem Biophys Res Commun 314 4 2004 1093 1099
43. Y. Bren-Mattison, V. Van Putten, and D. Chan Peroxisome proliferator-activated receptor-gamma (PPAR(gamma)) inhibits tumourigenesis by reversing the undifferentiated phenotype of metastatic non-small-cell lung cancer cells (NSCLC) Oncogene 24 8 2005 1412 1422
44. J.D. Liu, S.Y. Lin, and Y.S. Ho Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells Mol Carcinog 37 1 2003 16 24
45. S.J. Baek, L.C. Wilson, and L.C. Hsi Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumourigenic activity J Biol Chem 278 8 2003 5845 5853
46. A. Chawla, Y. Barak, and L. Nagy PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation Nat Med 7 1 2001 48 52
47. S.S. Palakurthi, H. Aktas, and L.M. Grubissich Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor {gamma} and mediated by inhibition of translation initiation Cancer Res 61 16 2001 6213 6218
48. A. Rossi, P. Kapahi, and G. Natoli Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase Nature 403 6765 2000 103 108
49. C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 5548 2001 1871 1875
50. L. Gelman, G. Zhou, and L. Fajas p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively J Biol Chem 274 12 1999 7681 7688
51. R.T. Nolte, G.B. Wisely, and S. Westin Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma Nature 395 6698 1998 137 143
52. V. Perissi, A. Aggarwal, and C.K. Glass A corepressor/co-activator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors Cell 116 4 2004 511 526
53. H.S. Camp, S.R. Tafuri, and T. Leff c-Jun N-Terminal kinase phosphorylates peroxisome proliferator-activated receptor-{gamma} 1 and negatively regulates its transcriptional activity Endocrinology 140 1 1999 392 397
54. E. Hu, J.B. Kim, and P. Sarraf Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ Science 274 1996 2100 2103
55. D. Shao, S.M. Rangwala, and S.T. Bailey Interdomain communication regulating ligand binding by PPAR-γ Nature 396 1998 377 380
56. M. Akaike, W. Che, and N.L. Marmarosh The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells Mol Cell Biol 24 19 2004 8691 8704
57. V.C. Jordan Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents J Med Chem 46 7 2003 1081 1111
58. V.C. Jordan Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions J Med Chem 46 6 2003 883 908
59. Y. Omoto, Y. Kobayashi, and K. Nishida Expression, function, and clinical implications of the estrogen receptor beta in human lung cancers Biochem Biophys Res Commun 285 2 2001 340 347
60. E. Radzikowska, R. Langfort, and D. Giedronowicz Estrogen and progesterone receptors in non small cell lung cancer patients Ann Thorac Cardiovasc Surg 8 2 2002 69 73
61. L.P. Stabile, A.L.G. Davis, and C.T. Gubish Human non-small cell lung tumours and cells derived from normal lung express both estrogen receptor {alpha} and {beta} and show biological responses to estrogen Cancer Res 62 7 2002 2141 2150
62. S. Mollerup, K. Jorgensen, and G. Berge Expression of estrogen receptors alpha and beta in human lung tissue and cell lines Lung Cancer 37 2 2002 153 159
63. G.G. Kuiper, and J.A. Gustafsson The novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens FEBS Lett 410 1 1997 87 90
64. D.P. Edwards Regulation of signal transduction pathways by estrogen and progesterone Annu Rev Physiol 67 2005 335 376
65. Z. Weihua, S. Andersson, and G. Cheng Update on estrogen signalling FEBS Lett 546 1 2003 17 24
66. L.P. Stabile, J.S. Lyker, and C.T. Gubish Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects Cancer Res 65 4 2005 1459 1470
67. K. Paech, P. Webb, and G.G. Kuiper Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites Science 277 5331 1997 1508 1510
68. K.W. Nettles, and G.L. Greene Ligand control of coregulator recruitment to nuclear receptors Annu Rev Physiol 67 2005 309 333
69. R. Kumar, and E.B. Thompson Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and co-activator interactions Mol Endocrinol 17 1 2003 1 10
70. P.A. Hershberger, A.C. Vasquez, and B. Kanterewicz Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands Cancer Res 65 4 2005 1598 1605
71. Y. Bren-Mattison, and B.B. Olwin Sonic hedgehog inhibits the terminal differentiation of limb myoblasts committed to the slow muscle lineage Dev Biol 242 2 2002 130 148
72. A.P. Dennis, and B. O'Malley Rush hour at the promoter: How the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcription J Steroid Biochem Mol Biol 93 2-5 2005 139 151