메뉴 건너뛰기




Volumn 37, Issue 1, 2003, Pages 16-24

Involvement of c-jun N-terminal kinase activation in 15-deoxy-Δ12,14-prostaglandin J2- and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells

Author keywords

Apoptosis; JNK; Prostaglandin

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ANTINEOPLASTIC AGENT; ARACHIDONIC ACID; CASPASE 3; DNA FRAGMENT; LEUKOTRIENE B4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN A1; PROSTAGLANDIN D2; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN H2; PROSTAGLANDIN J2; STRESS ACTIVATED PROTEIN KINASE; THROMBOXANE B2;

EID: 0038752800     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10119     Document Type: Article
Times cited : (34)

References (51)
  • 1
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Develop 1993;7:2135-2148.
    • (1993) Genes Develop , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 2
    • 0028229012 scopus 로고
    • The stress-activated protein kinase subfamily of c-Jun kinases
    • Kyriakis JM, Banerjee P, Nikolakaki E, et al. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 1994;369:156-160.
    • (1994) Nature , vol.369 , pp. 156-160
    • Kyriakis, J.M.1    Banerjee, P.2    Nikolakaki, E.3
  • 3
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud J, Gupta S, Rogers JS, et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 1995;270:7420-7426.
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3
  • 4
    • 0030041536 scopus 로고    scopus 로고
    • Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis
    • Chen YR, Meyer CF, Tan TH. Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. J Biol Chem 1996;271:631-634.
    • (1996) J Biol Chem , vol.271 , pp. 631-634
    • Chen, Y.R.1    Meyer, C.F.2    Tan, T.H.3
  • 5
    • 0030134173 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
    • Zanke BW, Boudreau K, Rubie E, et al. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Biol 1996;6:606-613.
    • (1996) Curr Biol , vol.6 , pp. 606-613
    • Zanke, B.W.1    Boudreau, K.2    Rubie, E.3
  • 6
    • 0027994002 scopus 로고
    • An osmosensing signal transduction pathway in mammalian cells
    • Galcheva-Gargova Z, Derijard B, Wu IH, Davis RJ. An osmosensing signal transduction pathway in mammalian cells. Science 1994;265:806-808.
    • (1994) Science , vol.265 , pp. 806-808
    • Galcheva-Gargova, Z.1    Derijard, B.2    Wu, I.H.3    Davis, R.J.4
  • 7
    • 0029828586 scopus 로고    scopus 로고
    • The Ras-JNK pathway is involved in shear-induced gene expression
    • Li YS, Shyy JY, Li S, et al. The Ras-JNK pathway is involved in shear-induced gene expression. Mol Cell Biol 1996;16:5947-5954.
    • (1996) Mol Cell Biol , vol.16 , pp. 5947-5954
    • Li, Y.S.1    Shyy, J.Y.2    Li, S.3
  • 9
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide initiated SAPK/JNK signalling in stress-induced apoptosis
    • Verheij M, Bose R, Lin XH, et al. Requirement for ceramide initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 1996;380:75-79.
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1    Bose, R.2    Lin, X.H.3
  • 10
    • 0033616709 scopus 로고    scopus 로고
    • Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis
    • Srivastava RK, Mi QS, Hardwick JM, Longo DL. Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis. Pro Nat Acad Sci USA 1999;96:3775-3780.
    • (1999) Pro Nat Acad Sci USA , vol.96 , pp. 3775-3780
    • Srivastava, R.K.1    Mi, Q.S.2    Hardwick, J.M.3    Longo, D.L.4
  • 11
    • 0035361599 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine
    • Fan M, Goodwin ME, Birrer MJ, Chambers TC. The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine. Cancer Res 2001; 61:4450-4458.
    • (2001) Cancer Res , vol.61 , pp. 4450-4458
    • Fan, M.1    Goodwin, M.E.2    Birrer, M.J.3    Chambers, T.C.4
  • 12
    • 0029851730 scopus 로고    scopus 로고
    • Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs
    • Osborn MT, Chambers TC. Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J Biol Chem 1996;271:30950-30955.
    • (1996) J Biol Chem , vol.271 , pp. 30950-30955
    • Osborn, M.T.1    Chambers, T.C.2
  • 13
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 14
    • 0032937879 scopus 로고    scopus 로고
    • Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death
    • Le-Niculescu H, Bonfoco E, Kasuya Y, Claret FX, Green DR, Karin M. Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol Cell Biol 1999;19:751-763.
    • (1999) Mol Cell Biol , vol.19 , pp. 751-763
    • Le-Niculescu, H.1    Bonfoco, E.2    Kasuya, Y.3    Claret, F.X.4    Green, D.R.5    Karin, M.6
  • 15
    • 0034607702 scopus 로고    scopus 로고
    • Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
    • Tournier C, Hess P, Yang DD, et al. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000;288:870-874.
    • (2000) Science , vol.288 , pp. 870-874
    • Tournier, C.1    Hess, P.2    Yang, D.D.3
  • 16
    • 0026754728 scopus 로고
    • Biological activities and mechanisms of action of PGJ2 and related compounds: An update
    • Fukushima M. Biological activities and mechanisms of action of PGJ2 and related compounds: An update. Prostagland Leukotri Essent Fatty Acids 1992;47:1-12.
    • (1992) Prostagland Leukotri Essent Fatty Acids , vol.47 , pp. 1-12
    • Fukushima, M.1
  • 17
    • 0001065185 scopus 로고
    • Prostaglandins with anti-proliferative activity induce the synthesis of a heat shock protein in human cells
    • Santoro MG, Garaci E, Amici C. Prostaglandins with anti-proliferative activity induce the synthesis of a heat shock protein in human cells. Proc Nat Acad Sci USA 1989;86:8407-8411.
    • (1989) Proc Nat Acad Sci USA , vol.86 , pp. 8407-8411
    • Santoro, M.G.1    Garaci, E.2    Amici, C.3
  • 18
    • 0025117981 scopus 로고
    • Specific role of an alpha, beta-unsaturated carbonyl group in gamma-glutamylcysteine synthetase induction by prostaglandin A2
    • Ohno K, Higaki J, Takechi S, Hirata M. Specific role of an alpha, beta-unsaturated carbonyl group in gamma-glutamylcysteine synthetase induction by prostaglandin A2. Chem Biol Interact 1990;76:77-87.
    • (1990) Chem Biol Interact , vol.76 , pp. 77-87
    • Ohno, K.1    Higaki, J.2    Takechi, S.3    Hirata, M.4
  • 19
    • 0025922869 scopus 로고
    • Prostaglandin D2 metabolite stimulates collagen synthesis by human osteoblasts during calcification
    • Tasaki Y, Takamori R, Koshihara Y. Prostaglandin D2 metabolite stimulates collagen synthesis by human osteoblasts during calcification. Prostaglandins 1991;41:303-313.
    • (1991) Prostaglandins , vol.41 , pp. 303-313
    • Tasaki, Y.1    Takamori, R.2    Koshihara, Y.3
  • 21
    • 0029162965 scopus 로고
    • Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene
    • Koizumi T, Odani N, Okuyama T, Ichikawa A, Negishi M. Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene. J Biol Chem 1995;270:21779-21784.
    • (1995) J Biol Chem , vol.270 , pp. 21779-21784
    • Koizumi, T.1    Odani, N.2    Okuyama, T.3    Ichikawa, A.4    Negishi, M.5
  • 22
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxi some proliferator-activated receptor gamma and promotes adipocyte differentiation
    • Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, Lehmann JM. A prostaglandin J2 metabolite binds peroxi some proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 1995;83:813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5    Lehmann, J.M.6
  • 23
    • 0035853707 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress
    • Kondo M, Oya-Ito T, Kumagai T, Osawa T, Uchida K. Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress. J Biol Chem 2001;276:12076-12083.
    • (2001) J Biol Chem , vol.276 , pp. 12076-12083
    • Kondo, M.1    Oya-Ito, T.2    Kumagai, T.3    Osawa, T.4    Uchida, K.5
  • 24
    • 0012954726 scopus 로고    scopus 로고
    • 2: The endogenous electrophile that induces neuronal apoptosis
    • 2: The endogenous electrophile that induces neuronal apoptosis. Proc Nat Acad Sci USA 2002;99:7367-7672.
    • (2002) Proc Nat Acad Sci USA , vol.99 , pp. 7367-7672
    • Kondo, M.1    Shibata, T.2    Kumagai, T.3
  • 25
    • 0035861657 scopus 로고    scopus 로고
    • Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells
    • Clay CE, Atsumi GI, High KP, Chilton FH. Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells. J Biol Chem 2001;276:47131-47135.
    • (2001) J Biol Chem , vol.276 , pp. 47131-47135
    • Clay, C.E.1    Atsumi, G.I.2    High, K.P.3    Chilton, F.H.4
  • 26
    • 0033213758 scopus 로고    scopus 로고
    • Inhibition of cyclindependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate
    • Liang YC, Lin-Shiau SY, Chen CF, Lin JK. Inhibition of cyclindependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate. J Cell Biochem 1999;75:1-12.
    • (1999) J Cell Biochem , vol.75 , pp. 1-12
    • Liang, Y.C.1    Lin-Shiau, S.Y.2    Chen, C.F.3    Lin, J.K.4
  • 27
    • 0032831286 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
    • Liang YC, Liang YC, Huang YT, Tsai SH, Lin-Shiau SY, Chen CF, Lin JK. Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis 1999;20:1945-1952.
    • (1999) Carcinogenesis , vol.20 , pp. 1945-1952
    • Liang, Y.C.1    Liang, Y.C.2    Huang, Y.T.3    Tsai, S.H.4    Lin-Shiau, S.Y.5    Chen, C.F.6    Lin, J.K.7
  • 29
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998;391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 30
    • 0035138625 scopus 로고    scopus 로고
    • PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti G, Lestavel S, Bocher V, et al. PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nature Med 2001;7:53-58.
    • (2001) Nature Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3
  • 31
    • 0035805144 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase through peroxisome proliferator-activated receptor-γ by apigenin and related-flavonoids in macrophages
    • Liang YC, Tsai DC, Lin-Shiau SY, Chen CF, Lin JK. Suppression of inducible cyclooxygenase and inducible nitric oxide synthase through peroxisome proliferator-activated receptor-γ by apigenin and related-flavonoids in macrophages. FEBS Lett 2001;496:12-18.
    • (2001) FEBS Lett , vol.496 , pp. 12-18
    • Liang, Y.C.1    Tsai, D.C.2    Lin-Shiau, S.Y.3    Chen, C.F.4    Lin, J.K.5
  • 32
    • 0035136965 scopus 로고    scopus 로고
    • Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 cleavage, c-Jun N-terminal kinase activation, and subsequent bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells
    • Shiah SG, Chuang SE, Kuo ML. Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 cleavage, c-Jun N-terminal kinase activation, and subsequent bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells. Mol Pharmacol 2001;59:254-262.
    • (2001) Mol Pharmacol , vol.59 , pp. 254-262
    • Shiah, S.G.1    Chuang, S.E.2    Kuo, M.L.3
  • 33
    • 0025616866 scopus 로고
    • Prostaglandin J2 - Anti-tumour and anti-viral activities and the mechanisms involved
    • Fukushima M. Prostaglandin J2 - anti-tumour and anti-viral activities and the mechanisms involved. Eicosanoids 1990;3:189-199.
    • (1990) Eicosanoids , vol.3 , pp. 189-199
    • Fukushima, M.1
  • 34
    • 0029750727 scopus 로고    scopus 로고
    • 2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity
    • Rossi A, Elia G, Santoro MG. 2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity. J Biol Chem 1996;271:32192-32196.
    • (1996) J Biol Chem , vol.271 , pp. 32192-32196
    • Rossi, A.1    Elia, G.2    Santoro, M.G.3
  • 35
    • 0035952497 scopus 로고    scopus 로고
    • 15-Deoxydelta 12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis
    • Rohn TT, Wong SM, Cotman CW, Cribbs DH. 15-deoxydelta 12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis. Neuro Report 2001;12:839-843.
    • (2001) Neuro Report , vol.12 , pp. 839-843
    • Rohn, T.T.1    Wong, S.M.2    Cotman, C.W.3    Cribbs, D.H.4
  • 36
    • 0034235142 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPARgamma agonists as inducers of apoptosis
    • Chattopadhyay N, Singh DP, Heese O, et al. Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPARgamma agonists as inducers of apoptosis. J Biol Chem 2000;61:67-74.
    • (2000) J Biol Chem , vol.61 , pp. 67-74
    • Chattopadhyay, N.1    Singh, D.P.2    Heese, O.3
  • 37
    • 0033533535 scopus 로고    scopus 로고
    • 15-Deoxy-delta (12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptorgamma, induces apoptosis in JEG3 choriocarcinoma cells
    • Keelan JA, Sato TA, Marvin KW, Lander J, Gilmour RS, Mitchell MD. 15-Deoxy-Delta (12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptorgamma, induces apoptosis in JEG3 choriocarcinoma cells. Biochem Biophy Res Commun 1999;262:579-585.
    • (1999) Biochem Biophy Res Commun , vol.262 , pp. 579-585
    • Keelan, J.A.1    Sato, T.A.2    Marvin, K.W.3    Lander, J.4    Gilmour, R.S.5    Mitchell, M.D.6
  • 38
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages
    • Chinetti G, Griglio S, Antonucci M, et al. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. J Biol Chem 1998;273:25573-25580.
    • (1998) J Biol Chem , vol.273 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3
  • 39
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E, Müller C, Koshizuka K, et al. Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Nat Acad Sci USA 2001;95:8806-8811.
    • (2001) Proc Nat Acad Sci USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Müller, C.2    Koshizuka, K.3
  • 40
    • 0033546190 scopus 로고    scopus 로고
    • Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta 12, 14-prostaglandin J2
    • Bishop-Bailey D, Hla T. Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta 12, 14-prostaglandin J2. J Biol Chem 1999;274:17042-17048.
    • (1999) J Biol Chem , vol.274 , pp. 17042-17048
    • Bishop-Bailey, D.1    Hla, T.2
  • 41
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages
    • Chinetti G, Griglio S, Antonucci M, et al. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. J Biol Chem 1998;273:25573-25580.
    • (1998) J Biol Chem , vol.273 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3
  • 42
    • 0036164609 scopus 로고    scopus 로고
    • Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells
    • Harris SG, Phipps RP. Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. Immunology 2002;105:23-34.
    • (2002) Immunology , vol.105 , pp. 23-34
    • Harris, S.G.1    Phipps, R.P.2
  • 43
    • 0025276249 scopus 로고
    • Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2
    • Atsmon J, Sweetman BJ, Baertschi SW, Harris TM, Roberts LJ 2nd. Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2. Biochemistry 1990;29:3760-3765.
    • (1990) Biochemistry , vol.29 , pp. 3760-3765
    • Atsmon, J.1    Sweetman, B.J.2    Baertschi, S.W.3    Harris, T.M.4    Roberts L.J. II5
  • 44
    • 0026611713 scopus 로고
    • Formation of a prostaglandin A2-glutathione conjugate in L1210 mouse leukemia cells
    • Parker J, Ankel H. Formation of a prostaglandin A2-glutathione conjugate in L1210 mouse leukemia cells. Biochem Pharmacol 1992;43:1053-1060.
    • (1992) Biochem Pharmacol , vol.43 , pp. 1053-1060
    • Parker, J.1    Ankel, H.2
  • 45
    • 0035929592 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit
    • Cernuda-Morollon E, Pineda-Molina E, Canada FJ, Perez-Sala D. 15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit. J Biol Chem 2001;276:35530-35536.
    • (2001) J Biol Chem , vol.276 , pp. 35530-35536
    • Cernuda-Morollon, E.1    Pineda-Molina, E.2    Canada, F.J.3    Perez-Sala, D.4
  • 46
    • 0034610759 scopus 로고    scopus 로고
    • Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase
    • Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, Santoro MG. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature 2000;403:103-108.
    • (2000) Nature , vol.403 , pp. 103-108
    • Rossi, A.1    Kapahi, P.2    Natoli, G.3    Takahashi, T.4    Chen, Y.5    Karin, M.6    Santoro, M.G.7
  • 47
    • 0034712933 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway
    • Straus DS, Pascual G, Li M, et al. 15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc Nat Acad Sci USA 2000;97:4844-4849.
    • (2000) Proc Nat Acad Sci USA , vol.97 , pp. 4844-4849
    • Straus, D.S.1    Pascual, G.2    Li, M.3
  • 48
    • 0032126479 scopus 로고    scopus 로고
    • Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1beta-converting enzyme inhibition
    • Zanke BW, Lee C, Arab S, Tannock IF. Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1beta-converting enzyme inhibition. Cancer Res 1998;58:2801-2808.
    • (1998) Cancer Res , vol.58 , pp. 2801-2808
    • Zanke, B.W.1    Lee, C.2    Arab, S.3    Tannock, I.F.4
  • 49
    • 0031029214 scopus 로고    scopus 로고
    • Stress-signalling kinase Sekl protects thymocytes from apoptosis mediated by CD95 and CD3
    • Nishina H, Fischer KD, Radvanyi L, et al. Stress-signalling kinase Sekl protects thymocytes from apoptosis mediated by CD95 and CD3. Nature 1997;385:350-353.
    • (1997) Nature , vol.385 , pp. 350-353
    • Nishina, H.1    Fischer, K.D.2    Radvanyi, L.3
  • 50
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-Jun N-terminal kinase(JNK) - From inflammation to development
    • Ip YT, Davis RJ. Signal transduction by the c-Jun N-terminal kinase(JNK) - from inflammation to development. Curr Opin Cell Biol 1998;10:205-219.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 51
    • 0037640249 scopus 로고    scopus 로고
    • www.CaymanChem.com


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.