Troglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) ligand, selectively induces the early growth response-1 gene independently of PPARγ: A novel mechanism for its anti-tumorigenic activity

Journal of Biological Chemistry

Volumn 278, Issue 8, 2003, Pages 5845-5853

  Baek, Seung Joon ^b   Wilson, Leigh C ^b   Hsi, Linda C ^b   Eling, Thomas E ^a  

^a Lab of Molecular Carcinogenesis   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELLS; RNA; TUMORS;

PHOSPHORYLATION;

BIOCHEMISTRY;

EARLY GROWTH RESPONSE FACTOR 1; LIGAND; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TROGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTINEOPLASTIC AGENT; CELL RECEPTOR; CHROMAN DERIVATIVE; DACTINOMYCIN; DNA BINDING PROTEIN; EGR1 PROTEIN, HUMAN; IMMEDIATE EARLY PROTEIN; PRIMER DNA; RECOMBINANT PROTEIN; RNA; THIAZOLE DERIVATIVE; ZINC FINGER PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING SITE; BIOSYNTHESIS; COLON CANCER; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; 3' UNTRANSLATED REGION; CELL CULTURE; CELL DIVISION; CELL STRAIN K 562; COLORECTAL TUMOR; DRUG EFFECT; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PLASMID;

3' UNTRANSLATED REGIONS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE SEQUENCE; CELL DIVISION; CHROMANS; COLORECTAL NEOPLASMS; DACTINOMYCIN; DNA PRIMERS; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMEDIATE-EARLY PROTEINS; K562 CELLS; PLASMIDS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; ZINC FINGERS;

EID: 0037458680     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208394200     Document Type: Article

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