-
1
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
L.I. Brujin, T.M. Miller, and D.W. Cleveland Unraveling the mechanisms involved in motor neuron degeneration in ALS Annu Rev Neurosci 27 2004 723
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 723
-
-
Brujin, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
2
-
-
0038693216
-
The basic aspects of therapeutics in amyotrophic lateral sclerosis
-
M.J. Strong The basic aspects of therapeutics in amyotrophic lateral sclerosis Pharmacol Ther 98 2003 379
-
(2003)
Pharmacol Ther
, vol.98
, pp. 379
-
-
Strong, M.J.1
-
4
-
-
0003760767
-
Amyotrophic lateral sclerosis
-
R.H. Brown V. Meininger M. Swash Martin Dunitz London
-
R.H. Brown, V. Meininger, and M. Swash Amyotrophic lateral sclerosis R.H. Brown V. Meininger M. Swash Amyotrophic lateral sclerosis 2000 Martin Dunitz London
-
(2000)
Amyotrophic Lateral Sclerosis
-
-
Brown, R.H.1
Meininger, V.2
Swash, M.3
-
5
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
D.R. Rosen, T. Siddique, and D. Patterson Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis Nature 362 1993 59
-
(1993)
Nature
, vol.362
, pp. 59
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
6
-
-
0036212119
-
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading
-
J.R. Subramaniam, W.E. Lyons, and J. Liu Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading Nat Neurosci 5 2002 301
-
(2002)
Nat Neurosci
, vol.5
, pp. 301
-
-
Subramaniam, J.R.1
Lyons, W.E.2
Liu, J.3
-
7
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
D.W. Cleveland, and J.D. Rothstein From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS Nat Rev Neurosci 2 2001 806
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 806
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
8
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
L.I. Bruijn, M.W. Becher, and M.K. Lee ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions Neuron 18 1997 327
-
(1997)
Neuron
, vol.18
, pp. 327
-
-
Bruijn, L.I.1
Becher, M.W.2
Lee, M.K.3
-
9
-
-
0001136455
-
Transgenic animal models of amyotrophic lateral sclerosis
-
R.H. Brown V. Meininger M. Swash Martin Dunitz London
-
M.E. Gurney Transgenic animal models of amyotrophic lateral sclerosis R.H. Brown V. Meininger M. Swash Amyotrophic lateral sclerosis 2000 Martin Dunitz London 251
-
(2000)
Amyotrophic Lateral Sclerosis
, pp. 251
-
-
Gurney, M.E.1
-
10
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
M.E. Gurney, H. Pu, and A.Y. Chiu Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation Science 264 1994 1772
-
(1994)
Science
, vol.264
, pp. 1772
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
-
11
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1mutant-mediated amyotrophic lateral sclerosis (ALS)
-
D.S. Howland, J. Liu, and Y. She Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1mutant-mediated amyotrophic lateral sclerosis (ALS) Proc Natl Acad Sci U S A 99 2002 1604
-
(2002)
Proc Natl Acad Sci U S a
, vol.99
, pp. 1604
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
-
12
-
-
0035575761
-
Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: Associated mutations develop motor neuron disease
-
M. Nagai, M. Aoki, and I. Miyoshi Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease J Neurosci 21 2001 9246
-
(2001)
J Neurosci
, vol.21
, pp. 9246
-
-
Nagai, M.1
Aoki, M.2
Miyoshi, I.3
-
13
-
-
0036847816
-
Microglia as neuroprotecitve, immunocompetent cells of the CNS
-
W.J. Streit Microglia as neuroprotecitve, immunocompetent cells of the CNS Glia 40 2002 133
-
(2002)
Glia
, vol.40
, pp. 133
-
-
Streit, W.J.1
-
14
-
-
0030222037
-
Microglia: A sensor for pathological events in the CNS
-
G.W. Kreutzberg Microglia: a sensor for pathological events in the CNS Trends Neurosci 19 1996 312
-
(1996)
Trends Neurosci
, vol.19
, pp. 312
-
-
Kreutzberg, G.W.1
-
15
-
-
22244464662
-
ATP mediates rapid microglial response to local brain injury in vivo
-
D. Davalos, J. Grutzendler, and G. Yang ATP mediates rapid microglial response to local brain injury in vivo Nat Neurosci 8 2005 752
-
(2005)
Nat Neurosci
, vol.8
, pp. 752
-
-
Davalos, D.1
Grutzendler, J.2
Yang, G.3
-
16
-
-
22244458574
-
Neuroscience: Brain under surveillance. the microglia patrol
-
L. Fetler, and S. Amigorena Neuroscience: brain under surveillance. The microglia patrol Science 309 2005 392
-
(2005)
Science
, vol.309
, pp. 392
-
-
Fetler, L.1
Amigorena, S.2
-
17
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
A. Nimmerjahn, F. Kirchhoff, and F. Helmchen Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo Science 308 2005 1314
-
(2005)
Science
, vol.308
, pp. 1314
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
18
-
-
0036849018
-
Microglia as a source and target of cytokines
-
U.K. Hanisch Microglia as a source and target of cytokines Glia 40 2002 140
-
(2002)
Glia
, vol.40
, pp. 140
-
-
Hanisch, U.K.1
-
19
-
-
0036847841
-
Microglia as liaisons between the immune and central nervous system: Functional implications in multiple sclerosis
-
M.J. Carson Microglia as liaisons between the immune and central nervous system: functional implications in multiple sclerosis Glia 40 2002 218
-
(2002)
Glia
, vol.40
, pp. 218
-
-
Carson, M.J.1
-
20
-
-
0036848969
-
Microglia in human immunodeficiency virus-associated neurodegeneration
-
G.A. Garden Microglia in human immunodeficiency virus-associated neurodegeneration Glia 40 2002 240
-
(2002)
Glia
, vol.40
, pp. 240
-
-
Garden, G.A.1
-
21
-
-
0036685522
-
Inflammation in neurodegenerative disease: A double-edged sword
-
T. Wyss-Coray, and L. Mucke Inflammation in neurodegenerative disease: a double-edged sword Neuron 35 2002 419
-
(2002)
Neuron
, vol.35
, pp. 419
-
-
Wyss-Coray, T.1
Mucke, L.2
-
22
-
-
0036850023
-
Neuroinflammation in Alzheimer's disease and prion disease
-
P. Eikelenboom, C. Bate, and W.A. Van Gool Neuroinflammation in Alzheimer's disease and prion disease Glia 40 2002 232
-
(2002)
Glia
, vol.40
, pp. 232
-
-
Eikelenboom, P.1
Bate, C.2
Van Gool, W.A.3
-
23
-
-
0032731763
-
Brain inflammation in Alzheimer disease and the therapeutic implications
-
E.G. McGeer, and P.L. McGeer Brain inflammation in Alzheimer disease and the therapeutic implications Curr Pharm Des 5 1999 821
-
(1999)
Curr Pharm des
, vol.5
, pp. 821
-
-
McGeer, E.G.1
McGeer, P.L.2
-
24
-
-
0345189366
-
Inflammatory blockade restores adult hippocampal neurogenesis
-
M.L. Monje, H. Toda, and T.D. Palmer Inflammatory blockade restores adult hippocampal neurogenesis Science 302 2003 1760
-
(2003)
Science
, vol.302
, pp. 1760
-
-
Monje, M.L.1
Toda, H.2
Palmer, T.D.3
-
25
-
-
0035132167
-
Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
-
G. Almer, C. Guegan, and P. Teismann Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis Ann Neurol 49 2001 176
-
(2001)
Ann Neurol
, vol.49
, pp. 176
-
-
Almer, G.1
Guegan, C.2
Teismann, P.3
-
26
-
-
0035500386
-
Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
-
J.L. Elliott Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis Brain Res Mol Brain Res 95 2001 172
-
(2001)
Brain Res Mol Brain Res
, vol.95
, pp. 172
-
-
Elliott, J.L.1
-
27
-
-
0036062628
-
Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
-
K. Hensley, R.A. Floyd, and B. Gordon Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis J Neurochem 82 2002 365
-
(2002)
J Neurochem
, vol.82
, pp. 365
-
-
Hensley, K.1
Floyd, R.A.2
Gordon, B.3
-
28
-
-
0034765498
-
Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin-1beta in neurodegeneration
-
M.D. Nguyen, J.P. Julien, and S. Rivest Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration Ann Neurol 50 2001 630
-
(2001)
Ann Neurol
, vol.50
, pp. 630
-
-
Nguyen, M.D.1
Julien, J.P.2
Rivest, S.3
-
29
-
-
0035194691
-
Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord
-
M.K. Olsen, S.L. Roberds, and B.R. Ellerbrock Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord Ann Neurol 50 2001 730
-
(2001)
Ann Neurol
, vol.50
, pp. 730
-
-
Olsen, M.K.1
Roberds, S.L.2
Ellerbrock, B.R.3
-
30
-
-
9644273779
-
Inflammatory mediators and growth factors in the spinal cord of G93A SOD1 rats
-
Y. Xie, P. Weydt, and D.S. Howland Inflammatory mediators and growth factors in the spinal cord of G93A SOD1 rats Neuroreport 15 2004 2513
-
(2004)
Neuroreport
, vol.15
, pp. 2513
-
-
Xie, Y.1
Weydt, P.2
Howland, D.S.3
-
31
-
-
0036269810
-
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
-
T. Yoshihara, S. Ishigaki, and M. Yamamoto Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis J Neurochem 80 2002 158
-
(2002)
J Neurochem
, vol.80
, pp. 158
-
-
Yoshihara, T.1
Ishigaki, S.2
Yamamoto, M.3
-
32
-
-
0035833937
-
Immune reactivity in a mouse model of familial ALS correlates with disease progression
-
M.E. Alexianu, M. Kozovska, and S.H. Appel Immune reactivity in a mouse model of familial ALS correlates with disease progression Neurology 57 2001 1282
-
(2001)
Neurology
, vol.57
, pp. 1282
-
-
Alexianu, M.E.1
Kozovska, M.2
Appel, S.H.3
-
33
-
-
0027473452
-
Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
-
J.I. Engelhardt, J. Tajti, and S.H. Appel Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis Arch Neurol 50 1993 30
-
(1993)
Arch Neurol
, vol.50
, pp. 30
-
-
Engelhardt, J.I.1
Tajti, J.2
Appel, S.H.3
-
34
-
-
0026605961
-
Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue
-
T. Kawamata, H. Akiyama, and T. Yamada Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue Am J Pathol 140 1992 691
-
(1992)
Am J Pathol
, vol.140
, pp. 691
-
-
Kawamata, T.1
Akiyama, H.2
Yamada, T.3
-
35
-
-
0035153212
-
Immune function of astrocytes
-
Y. Dong, and E.N. Benveniste Immune function of astrocytes Glia 36 2001 180
-
(2001)
Glia
, vol.36
, pp. 180
-
-
Dong, Y.1
Benveniste, E.N.2
-
36
-
-
0035149257
-
Control of glial immune function by neurons
-
H. Neumann Control of glial immune function by neurons Glia 36 2001 191
-
(2001)
Glia
, vol.36
, pp. 191
-
-
Neumann, H.1
-
37
-
-
0033018506
-
Inducible nitric oxide synthase upregulation in a transgenic model of familial amyotrophic lateral sclerosis
-
G. Almer, S. Vukosavic, and N. Romero Inducible nitric oxide synthase upregulation in a transgenic model of familial amyotrophic lateral sclerosis J Neurochem 72 1999 2415
-
(1999)
J Neurochem
, vol.72
, pp. 2415
-
-
Almer, G.1
Vukosavic, S.2
Romero, N.3
-
38
-
-
0032125587
-
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
-
E.D. Hall, J.A. Oostveen, and M.E. Gurney Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS Glia 23 1998 249
-
(1998)
Glia
, vol.23
, pp. 249
-
-
Hall, E.D.1
Oostveen, J.A.2
Gurney, M.E.3
-
39
-
-
0034640139
-
Activation and response to axotomy of microglia in the facial motor nuclei of G93A superoxide dismutase transgenic mice
-
R. Mariotti, and M. Bentivoglio Activation and response to axotomy of microglia in the facial motor nuclei of G93A superoxide dismutase transgenic mice Neurosci Lett 285 2000 87
-
(2000)
Neurosci Lett
, vol.285
, pp. 87
-
-
Mariotti, R.1
Bentivoglio, M.2
-
40
-
-
0344838679
-
Neuro-inflammation as a therapeutic target in amyotrophic lateral sclerosis
-
P. Weydt, M.D. Weiss, and T. Moller Neuro-inflammation as a therapeutic target in amyotrophic lateral sclerosis Curr Opin Investig Drugs 3 2002 1720
-
(2002)
Curr Opin Investig Drugs
, vol.3
, pp. 1720
-
-
Weydt, P.1
Weiss, M.D.2
Moller, T.3
-
41
-
-
9144230806
-
Increased cytotoxic potential of microglia from ALS-transgenic mice
-
P. Weydt, E.C. Yuen, and B.R. Ransom Increased cytotoxic potential of microglia from ALS-transgenic mice Glia 48 2004 179
-
(2004)
Glia
, vol.48
, pp. 179
-
-
Weydt, P.1
Yuen, E.C.2
Ransom, B.R.3
-
42
-
-
0029792449
-
Familial amyotrophic lateral sclerosis with a mutation in exon 4 of the Cu/Zn superoxide dismutase gene: Pathological and immunocytochemical changes
-
P.G. Ince, P.J. Shaw, and J.Y. Slade Familial amyotrophic lateral sclerosis with a mutation in exon 4 of the Cu/Zn superoxide dismutase gene: pathological and immunocytochemical changes Acta Neuropathol (Berl) 92 1996 395
-
(1996)
Acta Neuropathol (Berl)
, vol.92
, pp. 395
-
-
Ince, P.G.1
Shaw, P.J.2
Slade, J.Y.3
-
43
-
-
1842471942
-
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: An [11C](R)-PK11195 positron emission tomography study
-
M.R. Turner, A. Cagnin, and F.E. Turkheimer Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study Neurobiol Dis 15 2004 601
-
(2004)
Neurobiol Dis
, vol.15
, pp. 601
-
-
Turner, M.R.1
Cagnin, A.2
Turkheimer, F.E.3
-
44
-
-
19944434347
-
Evidence for systemic immune system alterations in sporadic amyotrophic lateral sclerosis (sALS)
-
R. Zhang, R. Gascon, and R.G. Miller Evidence for systemic immune system alterations in sporadic amyotrophic lateral sclerosis (sALS) J Neuroimmunol 159 2005 215
-
(2005)
J Neuroimmunol
, vol.159
, pp. 215
-
-
Zhang, R.1
Gascon, R.2
Miller, R.G.3
-
45
-
-
0037000396
-
Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier
-
M. Fiala, Q.N. Liu, and J. Sayre Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier Eur J Clin Invest 32 2002 360
-
(2002)
Eur J Clin Invest
, vol.32
, pp. 360
-
-
Fiala, M.1
Liu, Q.N.2
Sayre, J.3
-
46
-
-
0034651102
-
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
-
Y.H. Gong, A.S. Parsadanian, and A. Andreeva Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration J Neurosci 20 2000 660
-
(2000)
J Neurosci
, vol.20
, pp. 660
-
-
Gong, Y.H.1
Parsadanian, A.S.2
Andreeva, A.3
-
47
-
-
0037096354
-
Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
-
M.M. Lino, C. Schneider, and P. Caroni Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease J Neurosci 22 2002 4825
-
(2002)
J Neurosci
, vol.22
, pp. 4825
-
-
Lino, M.M.1
Schneider, C.2
Caroni, P.3
-
48
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
A. Pramatarova, J. Laganiere, and J. Roussel Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment J Neurosci 21 2001 3369
-
(2001)
J Neurosci
, vol.21
, pp. 3369
-
-
Pramatarova, A.1
Laganiere, J.2
Roussel, J.3
-
49
-
-
0141642203
-
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
-
A.M. Clement, M.D. Nguyen, and E.A. Roberts Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice Science 302 2003 113
-
(2003)
Science
, vol.302
, pp. 113
-
-
Clement, A.M.1
Nguyen, M.D.2
Roberts, E.A.3
-
50
-
-
0037068836
-
Motoneuron death triggered by a specific pathway downstream of Fas potentiation by ALS-linked SOD1 mutations
-
C. Raoul, A.G. Estevez, and H. Nishimune Motoneuron death triggered by a specific pathway downstream of Fas potentiation by ALS-linked SOD1 mutations Neuron 35 2002 1067
-
(2002)
Neuron
, vol.35
, pp. 1067
-
-
Raoul, C.1
Estevez, A.G.2
Nishimune, H.3
-
51
-
-
0033366461
-
SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter
-
D. Trotti, A. Rolfs, and N.C. Danbolt SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter Nat Neurosci 2 1999 427 [Erratum appears in Nat Neurosci 1999;2(9):848.]
-
(1999)
Nat Neurosci
, vol.2
, pp. 427
-
-
Trotti, D.1
Rolfs, A.2
Danbolt, N.C.3
-
52
-
-
26244438751
-
Motor neuron growth and death
-
Presidential symposium: From Charcot to Lou Gehrig. San Diego, October 24
-
Cleveland DW. Presidential symposium: from Charcot to Lou Gehrig. Motor neuron growth and death. Presented at the 34th Annual Meeting of the Society for Neuroscience. San Diego, October 24, 2004.
-
(2004)
34th Annual Meeting of the Society for Neuroscience
-
-
Cleveland, D.W.1
-
53
-
-
26244451092
-
Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA
-
J. Wang, G. Xu, and H.H. Slunt Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA Neurobiol Dis 2005 in press
-
(2005)
Neurobiol Dis
-
-
Wang, J.1
Xu, G.2
Slunt, H.H.3
-
54
-
-
0034728639
-
Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy
-
F. Lopez-Redondo, K. Nakajima, and S. Honda Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy Brain Res Mol Brain Res 76 2000 429
-
(2000)
Brain Res Mol Brain Res
, vol.76
, pp. 429
-
-
Lopez-Redondo, F.1
Nakajima, K.2
Honda, S.3
-
55
-
-
0032989129
-
Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct
-
K.H. Plate, H. Beck, and S. Danner Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct J Neuropathol Exp Neurol 58 1999 654
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 654
-
-
Plate, K.H.1
Beck, H.2
Danner, S.3
-
56
-
-
14944342151
-
COX-2 inhibitors: A lesson in unexpected problems
-
J.M. Drazen COX-2 inhibitors: a lesson in unexpected problems N Engl J Med 352 2005 1131
-
(2005)
N Engl J Med
, vol.352
, pp. 1131
-
-
Drazen, J.M.1
-
57
-
-
0036895241
-
Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS
-
D.B. Drachman, K. Frank, and M. Dykes-Hoberg Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS Ann Neurol 52 2002 771
-
(2002)
Ann Neurol
, vol.52
, pp. 771
-
-
Drachman, D.B.1
Frank, K.2
Dykes-Hoberg, M.3
-
58
-
-
17444367702
-
Integrative role of cPLA with COX-2 and the effect of non-steroidal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis
-
M. Kiaei, K. Kipiani, and S. Petri Integrative role of cPLA with COX-2 and the effect of non-steroidal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis J Neurochem 93 2005 403
-
(2005)
J Neurochem
, vol.93
, pp. 403
-
-
Kiaei, M.1
Kipiani, K.2
Petri, S.3
-
59
-
-
4344680646
-
Additive neuroprotective effects of creatine and a cyclooxygenase 2 inhibitor against dopamine depletion in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) mouse model of Parkinson's disease
-
P. Klivenyi, G. Gardian, and N.Y. Calingasan Additive neuroprotective effects of creatine and a cyclooxygenase 2 inhibitor against dopamine depletion in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease J Mol Neurosci 21 2003 191
-
(2003)
J Mol Neurosci
, vol.21
, pp. 191
-
-
Klivenyi, P.1
Gardian, G.2
Calingasan, N.Y.3
-
60
-
-
1842714301
-
Neuroinflammation, COX-2, and ALS: A dual role?
-
C. Consilvio, A.M. Vincent, and E.L. Feldman Neuroinflammation, COX-2, and ALS: a dual role? Exp Neurol 187 2004 1
-
(2004)
Exp Neurol
, vol.187
, pp. 1
-
-
Consilvio, C.1
Vincent, A.M.2
Feldman, E.L.3
-
61
-
-
0037389393
-
A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
-
P.N. Pompl, L. Ho, and M. Bianchi A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis FASEB J 17 2003 725
-
(2003)
FASEB J
, vol.17
, pp. 725
-
-
Pompl, P.N.1
Ho, L.2
Bianchi, M.3
-
62
-
-
0035871840
-
Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
-
T. Tikka, B.L. Fiebich, and G. Goldsteins Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia J Neurosci 21 2001 2580
-
(2001)
J Neurosci
, vol.21
, pp. 2580
-
-
Tikka, T.1
Fiebich, B.L.2
Goldsteins, G.3
-
63
-
-
0034801488
-
Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation
-
T. Tikka, T. Usenius, and M. Tenhunen Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation J Neurochem 78 2001 1409
-
(2001)
J Neurochem
, vol.78
, pp. 1409
-
-
Tikka, T.1
Usenius, T.2
Tenhunen, M.3
-
64
-
-
0035876916
-
Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia
-
T.M. Tikka, and J.E. Koistinaho Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia J Immunol 166 2001 7527
-
(2001)
J Immunol
, vol.166
, pp. 7527
-
-
Tikka, T.M.1
Koistinaho, J.E.2
-
66
-
-
0036406903
-
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis
-
J. Kriz, M. Nguyen, and J. Julien Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis Neurobiol Dis 10 2002 268
-
(2002)
Neurobiol Dis
, vol.10
, pp. 268
-
-
Kriz, J.1
Nguyen, M.2
Julien, J.3
-
67
-
-
0037067009
-
Minocycline delays disease onset and mortality in a transgenic model of ALS
-
L. Van Den Bosch, P. Tilkin, and G. Lemmens Minocycline delays disease onset and mortality in a transgenic model of ALS Neuroreport 13 2002 1067
-
(2002)
Neuroreport
, vol.13
, pp. 1067
-
-
Van Den Bosch, L.1
Tilkin, P.2
Lemmens, G.3
-
68
-
-
0037007645
-
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
-
S. Zhu, I.G. Stavrovskaya, and M. Drozda Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice Nature 417 2002 74
-
(2002)
Nature
, vol.417
, pp. 74
-
-
Zhu, S.1
Stavrovskaya, I.G.2
Drozda, M.3
-
69
-
-
2442715084
-
Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis
-
P.H. Gordon, D.H. Moore, and D.F. Gelinas Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis Neurology 62 2004 1845
-
(2004)
Neurology
, vol.62
, pp. 1845
-
-
Gordon, P.H.1
Moore, D.H.2
Gelinas, D.F.3
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