Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS

Annals of Neurology

Volumn 52, Issue 6, 2002, Pages 771-778

  Drachman, Daniel B ^a   Frank, Krystl ^a   Dykes Hoberg, Margaret ^a   Teismann, Peter ^b   Almer, Gabrielle ^b,c   Przedborski, Serge ^b   Rothstein, Jeffrey D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Columbia University ^*  (United States)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; FREE RADICAL; GLUTAMIC ACID; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; MALE; MICROGLIA; MOUSE; MUSCLE WEAKNESS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; SURVIVAL; TRANSGENIC MOUSE; WEIGHT REDUCTION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; SULFONAMIDES; SURVIVAL RATE;

EID: 0036895241     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.10374     Document Type: Article

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