메뉴 건너뛰기




Volumn 58, Issue 6, 1999, Pages 654-666

Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct

Author keywords

Cerebrovascular disease; Hypoxia; Hypoxic preconditioning; Ischemia; Penumbra; VEGF

Indexed keywords

VASCULOTROPIN;

EID: 0032989129     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199906000-00010     Document Type: Article
Times cited : (226)

References (54)
  • 1
    • 0027487087 scopus 로고
    • Vascular endothelial growth factor
    • Ferrara N. Vascular endothelial growth factor. Trends Cardiovasc Sci 1993;3:244-50
    • (1993) Trends Cardiovasc Sci , vol.3 , pp. 244-250
    • Ferrara, N.1
  • 3
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature 1997;386:671-74
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 4
    • 0029021660 scopus 로고
    • Role of the flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G-H, Rossant J, Gertsenstein M, Breitman ML. Role of the flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995;376:66-70
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.-H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 6
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-39
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1    Ferreira, V.2    Breier, G.3
  • 7
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996;380:439-42
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3
  • 8
    • 0026593331 scopus 로고
    • Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
    • Breier G, Albrecht U, Sterrer S, Risau W. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 1992;114:521-32
    • (1992) Development , vol.114 , pp. 521-532
    • Breier, G.1    Albrecht, U.2    Sterrer, S.3    Risau, W.4
  • 9
    • 0028868619 scopus 로고
    • Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development
    • Breier G, Clauss M, Risau W. Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dynamics 1995;204:228-39
    • (1995) Dev Dynamics , vol.204 , pp. 228-239
    • Breier, G.1    Clauss, M.2    Risau, W.3
  • 10
    • 0027466849 scopus 로고
    • High affinity vegf binding and developmental expression suggest flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer B, Wizigmann-Voos S, Schnürch H, et al. High affinity VEGF binding and developmental expression suggest flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 1993;72: 835-46
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnürch, H.3
  • 11
    • 0027936452 scopus 로고
    • Role of angiogenesis in patients with cerebral ischemic stroke
    • Krupinski J, Kaluza J, Kumar P, Kumar S, Wang JM. Role of angiogenesis in patients with cerebral ischemic stroke. Stroke 1994;25:1794-98
    • (1994) Stroke , vol.25 , pp. 1794-1798
    • Krupinski, J.1    Kaluza, J.2    Kumar, P.3    Kumar, S.4    Wang, J.M.5
  • 12
    • 0019868418 scopus 로고
    • Focal cerebral ischemia in the rat. Description of technique and early neuropathological consequences following middle cerebral artery occlusion
    • Tamura A, Graham DI, McCulloch J, Teasdale GM. Focal cerebral ischemia in the rat. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1981;1:53-60
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 53-60
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3    Teasdale, G.M.4
  • 13
    • 0027310151 scopus 로고
    • Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP 40116 in a rat model of focal cerebral ischemia: An in vivo magnetic resonance imaging study
    • Sauer D, Allegrini PR, Cosenti A, Pataki A, Amacker A, Fagg GE. Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP 40116 in a rat model of focal cerebral ischemia: An in vivo magnetic resonance imaging study. J Cereb Blood Flow Metab 1993;13:595-602
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 595-602
    • Sauer, D.1    Allegrini, P.R.2    Cosenti, A.3    Pataki, A.4    Amacker, A.5    Fagg, G.E.6
  • 14
    • 0026660784 scopus 로고
    • Application of magnetic resonance imaging to the measurement of neurodegeneration in the rat brain: MRI data correlate strongly with histology and enzymatic analysis
    • Allegrini PR, Sauer D. Application of magnetic resonance imaging to the measurement of neurodegeneration in the rat brain: MRI data correlate strongly with histology and enzymatic analysis. Magn Reson Imag 1992;10:773-78
    • (1992) Magn Reson Imag , vol.10 , pp. 773-778
    • Allegrini, P.R.1    Sauer, D.2
  • 15
    • 33646376290 scopus 로고
    • Spin diffusion measurements: Spin echoes in the presence of a time-dependent field gradient
    • Stejskal EO, Tanner JE. Spin diffusion measurements: Spin echoes in the presence of a time-dependent field gradient. J Chem Phys 1965;42:282-92
    • (1965) J Chem Phys , vol.42 , pp. 282-292
    • Stejskal, E.O.1    Tanner, J.E.2
  • 16
    • 0030601207 scopus 로고    scopus 로고
    • A novel gene iba I in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage
    • Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S. A novel gene iba I in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biophys Biochem Res Commun 1996;224:855-62
    • (1996) Biophys Biochem Res Commun , vol.224 , pp. 855-862
    • Imai, Y.1    Ibata, I.2    Ito, D.3    Ohsawa, K.4    Kohsaka, S.5
  • 18
    • 0022654730 scopus 로고
    • Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognising complement receptor type 3
    • Robinson AP, White TM, Mason DW. Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognising complement receptor type 3. Immunology 1986;57:239-47
    • (1986) Immunology , vol.57 , pp. 239-247
    • Robinson, A.P.1    White, T.M.2    Mason, D.W.3
  • 19
    • 0028815295 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
    • Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci USA 1995;92:905-9
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 905-909
    • Pierce, E.A.1    Avery, R.L.2    Foley, E.D.3    Aiello, L.P.4    Smith, L.E.5
  • 20
    • 0029074024 scopus 로고
    • Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
    • Stone J, Itin A, Alon T, et al. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci 1995;15:4738-47
    • (1995) J Neurosci , vol.15 , pp. 4738-4747
    • Stone, J.1    Itin, A.2    Alon, T.3
  • 21
  • 22
    • 0028803509 scopus 로고
    • Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
    • Alon T, Hemo I, Itin A, Pe'er J, Stone J, Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med 1995;1:1024-28
    • (1995) Nat Med , vol.1 , pp. 1024-1028
    • Alon, T.1    Hemo, I.2    Itin, A.3    Pe'er, J.4    Stone, J.5    Keshet, E.6
  • 23
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992;359: 843-45
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 24
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo
    • Plate KH, Breier G, Weich HA, Risau W. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature 1992;359:845-48
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 25
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • Ikeda E, Achen MG, Breier G, Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem 1995;270: 19761-66
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.G.2    Breier, G.3    Risau, W.4
  • 26
    • 0030806074 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms
    • Damert A, Machein M, Breier G, et al. Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms. Cancer Research 1997;57:3860-64
    • (1997) Cancer Research , vol.57 , pp. 3860-3864
    • Damert, A.1    Machein, M.2    Breier, G.3
  • 27
    • 0032555459 scopus 로고    scopus 로고
    • Upregulation of vascular endothelial growth factor in severe chronic brain hypoxia of the rat
    • Patt S, Danner S, Theallier-Janko A, et al. Upregulation of vascular endothelial growth factor in severe chronic brain hypoxia of the rat. Neurosci Lett 1998;252:199-202
    • (1998) Neurosci Lett , vol.252 , pp. 199-202
    • Patt, S.1    Danner, S.2    Theallier-Janko, A.3
  • 28
    • 0027480731 scopus 로고
    • PET imaging of cerebral perfusion and oxygen consumption in acute ischemic stroke: Relation to outcome
    • Marchal G, Serrati C, Rioux P, et al. PET imaging of cerebral perfusion and oxygen consumption in acute ischemic stroke: Relation to outcome. Lancet 1993;341:925-27
    • (1993) Lancet , vol.341 , pp. 925-927
    • Marchal, G.1    Serrati, C.2    Rioux, P.3
  • 29
    • 0027432324 scopus 로고
    • Upregulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
    • Plate KH, Breier G, Millauer B, Ullrich A, Risau W. Upregulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res 1993;53: 5822-27
    • (1993) Cancer Res , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 30
    • 0023915805 scopus 로고
    • Neovasculature and blood-brain barrier in ischemic brain infarct
    • Liu HM. Neovasculature and blood-brain barrier in ischemic brain infarct. Acta Neuropathol (Berlin) 1988;75:422-26
    • (1988) Acta Neuropathol (Berlin) , vol.75 , pp. 422-426
    • Liu, H.M.1
  • 31
    • 0029745025 scopus 로고    scopus 로고
    • VEGF and flt: Expression time kinetics in rat brain infarct
    • Kovács Z, Ikezaki K, Samoto K, Inamura T, Fukui M. VEGF and flt: expression time kinetics in rat brain infarct. Stroke 1996;27: 1865-73
    • (1996) Stroke , vol.27 , pp. 1865-1873
    • Kovács, Z.1    Ikezaki, K.2    Samoto, K.3    Inamura, T.4    Fukui, M.5
  • 32
    • 0031683937 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat
    • Lennmyr F, Ata KA, Funa K, Olsson Y, Terént A. Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat. J Neuropathol Exp Neurol 1998;57: 874-82
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 874-882
    • Lennmyr, F.1    Ata, K.A.2    Funa, K.3    Olsson, Y.4    Terént, A.5
  • 33
    • 0030693379 scopus 로고    scopus 로고
    • Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats
    • Hayashi T, Abe K, Suzuki H, Itoyama Y. Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats. Stroke 1997;28:2039-44
    • (1997) Stroke , vol.28 , pp. 2039-2044
    • Hayashi, T.1    Abe, K.2    Suzuki, H.3    Itoyama, Y.4
  • 35
    • 0011987231 scopus 로고
    • Spreading depression: A behavioural analysis
    • JA Deutsch, ed. New York: Academic Press
    • Schneider AM, Simpson P. Spreading depression: A behavioural analysis. In: JA Deutsch, ed. The physiological basis of memory. New York: Academic Press, 1983;121-38
    • (1983) The Physiological Basis of Memory , pp. 121-138
    • Schneider, A.M.1    Simpson, P.2
  • 36
    • 0030574090 scopus 로고    scopus 로고
    • Monitoring the temporal and spatial activation pattern of astrocytes in focal cerebral ischemia using in situ hybridization to GFAP mRNA: Comparison with sgp-2 and hsp70 mRNA and the effect of glutamate receptor antagonists
    • Yamashita K, Vogel P, Fritze K, Back T, Hossmann KA, Wiessner C. Monitoring the temporal and spatial activation pattern of astrocytes in focal cerebral ischemia using in situ hybridization to GFAP mRNA: comparison with sgp-2 and hsp70 mRNA and the effect of glutamate receptor antagonists. Brain Res 1996;735:285-97
    • (1996) Brain Res , vol.735 , pp. 285-297
    • Yamashita, K.1    Vogel, P.2    Fritze, K.3    Back, T.4    Hossmann, K.A.5    Wiessner, C.6
  • 37
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
    • Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marine D. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996;87:3336-43
    • (1996) Blood , vol.87 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3    Weich, H.A.4    Mantovani, A.5    Marine, D.6
  • 38
    • 0030030668 scopus 로고    scopus 로고
    • Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression
    • Brogi E, Schatteman G, Kim EA, Varticovski L, Keyt B, Isner JM. Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. J Clin Invest 1996;97:469-76
    • (1996) J Clin Invest , vol.97 , pp. 469-476
    • Brogi, E.1    Schatteman, G.2    Kim, E.A.3    Varticovski, L.4    Keyt, B.5    Isner, J.M.6
  • 39
    • 0030609013 scopus 로고    scopus 로고
    • Vascular endothelial growth factor upregulates its receptor fms-like tyrosine kinase (flt-1) and a soluble variant of flt-1 in human vascular endothelial cells
    • Barleon B, Siemeister G, Martiny-Baron G, Weindel K, Herzog C, Marme D. Vascular endothelial growth factor upregulates its receptor fms-like tyrosine kinase (flt-1) and a soluble variant of flt-1 in human vascular endothelial cells. Cancer Res 1997;57:5421-25
    • (1997) Cancer Res , vol.57 , pp. 5421-5425
    • Barleon, B.1    Siemeister, G.2    Martiny-Baron, G.3    Weindel, K.4    Herzog, C.5    Marme, D.6
  • 40
    • 0030800782 scopus 로고    scopus 로고
    • Upregulation of flk-1/ VEGF receptor-2 by its ligand in a cerebral slice culture system
    • Kremer C, Breier G, Risau W, Plate KH. Upregulation of flk-1/ VEGF receptor-2 by its ligand in a cerebral slice culture system. Cancer Research 1997;57:3852-59
    • (1997) Cancer Research , vol.57 , pp. 3852-3859
    • Kremer, C.1    Breier, G.2    Risau, W.3    Plate, K.H.4
  • 41
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber HP, Condorelli F, Park J, Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem 1997;272:23659-67
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 42
    • 0029758798 scopus 로고    scopus 로고
    • Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia
    • Waltenberger J, Mayr U, Pentz S, Hombach V. Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia. Circulation 1996;94:1647-54
    • (1996) Circulation , vol.94 , pp. 1647-1654
    • Waltenberger, J.1    Mayr, U.2    Pentz, S.3    Hombach, V.4
  • 44
    • 0028905230 scopus 로고
    • Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat
    • Li Y, Chopp M, Jiang N, Yao F, Zaloga C. Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1995;15:389-97
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 389-397
    • Li, Y.1    Chopp, M.2    Jiang, N.3    Yao, F.4    Zaloga, C.5
  • 45
    • 0029155806 scopus 로고
    • Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization
    • Drake CJ, Little CD. Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proc Natl Acad Sci USA 1995;92:7657-61
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7657-7661
    • Drake, C.J.1    Little, C.D.2
  • 46
    • 0028825887 scopus 로고
    • Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increases vascular permeability without alterations of embryonic pattern formation
    • Flamme I, von Reuterrn M, Drexler HCA, Syed-Ali S, Risau W. Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increases vascular permeability without alterations of embryonic pattern formation. Dev Biol 1995;171:399-441
    • (1995) Dev Biol , vol.171 , pp. 399-441
    • Flamme, I.1    Von Reuterrn, M.2    Drexler, H.C.A.3    Syed-Ali, S.4    Risau, W.5
  • 47
    • 0028971501 scopus 로고
    • VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo
    • Mühlhauser J, Merill MJ, Pili R, et al. VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo. Circ Res 1995;77:1077-86
    • (1995) Circ Res , vol.77 , pp. 1077-1086
    • Mühlhauser, J.1    Merill, M.J.2    Pili, R.3
  • 48
    • 0030665129 scopus 로고    scopus 로고
    • VEGF induces cardiovascular malformation and embryonic lethality
    • Feucht M, Christ B, Wilting J. VEGF induces cardiovascular malformation and embryonic lethality. Am J Pathol 1997;151:1407-16
    • (1997) Am J Pathol , vol.151 , pp. 1407-1416
    • Feucht, M.1    Christ, B.2    Wilting, J.3
  • 49
    • 0032499694 scopus 로고    scopus 로고
    • Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo
    • Rosenstein JM, Mani N, Silvermann WF, Krum JM. Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo. Proc Natl Acad Sci USA 1998;95: 7086-91
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7086-7091
    • Rosenstein, J.M.1    Mani, N.2    Silvermann, W.F.3    Krum, J.M.4
  • 51
    • 0028288687 scopus 로고
    • Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs
    • Banai S, Jaklitsch MT, Shou M, et al. Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 1994;89:2183-98
    • (1994) Circulation , vol.89 , pp. 2183-2198
    • Banai, S.1    Jaklitsch, M.T.2    Shou, M.3
  • 52
    • 15844420661 scopus 로고    scopus 로고
    • Clinical evidence of angiogenesis after arterial gene transfer of phvegf165 in patient with ischaemic limb
    • Isner JM, Pieczek A, Schainfield R, et al. Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996;348:370-74
    • (1996) Lancet , vol.348 , pp. 370-374
    • Isner, J.M.1    Pieczek, A.2    Schainfield, R.3
  • 53
    • 19144371999 scopus 로고    scopus 로고
    • Arterial gene transfer for therapeutic angiogenesis in patients with peripheral artery disease
    • Isner JM, Walsh K, Symes J, et al. Arterial gene transfer for therapeutic angiogenesis in patients with peripheral artery disease. Hum Gen Ther 1996;7:959-88
    • (1996) Hum Gen Ther , vol.7 , pp. 959-988
    • Isner, J.M.1    Walsh, K.2    Symes, J.3
  • 54
    • 0031826273 scopus 로고    scopus 로고
    • Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia
    • Hayashi T, Abe K, Itoyama Y. Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia. J Cereb Blood Flow Metab 1998;18:887-95
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 887-895
    • Hayashi, T.1    Abe, K.2    Itoyama, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.