-
1
-
-
0037686295
-
Killing the messenger: Short RNAs that silence gene expression
-
Dykxhoorn, D.M., C.D. Novina, and P.A. Sharp. 2003. Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol 4:457-467.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 457-467
-
-
Dykxhoorn, D.M.1
Novina, C.D.2
Sharp, P.A.3
-
2
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
Meister, G. and T. Tuschl. 2004. Mechanisms of gene silencing by double-stranded RNA. Nature 437:343-349.
-
(2004)
Nature
, vol.437
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
3
-
-
0037062951
-
RNA interference
-
Hannon, G.J. 2002. RNA interference. Nature 418:244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
4
-
-
0036653097
-
RNA interference: The new somatic cell genetics?
-
Paddison, P.J. and G.J. Hannon. 2002. RNA interference: the new somatic cell genetics? Cancer Cell 2:17-23.
-
(2002)
Cancer Cell
, vol.2
, pp. 17-23
-
-
Paddison, P.J.1
Hannon, G.J.2
-
5
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir, S.M., J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
6
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen, N.J., S. Parrish, F. Imani, A. Fire, and R.A. Morgan. 2001. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl Acad. Sci. USA 98:9742-9747.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
7
-
-
1942499451
-
Improving the efficiency of RNA interference in mammals
-
Mittal, V. 2004. Improving the efficiency of RNA interference in mammals. Nat. Rev. Genet. 5:355-365.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 355-365
-
-
Mittal, V.1
-
8
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
Hannon, G.J. and J.J. Rossi. 2004. Unlocking the potential of the human genome with RNA interference. Nature 431:371-378.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
9
-
-
0037804642
-
Whither RNAi?
-
2003. Whither RNAi? Nat. Cell Biol. 5:489-490.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 489-490
-
-
-
10
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
Yang, D., F. Buchholz, Z. Huang, A. Goga, C.Y. Chen, F.M. Brodsky, and J.M. Bishop. 2002. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 99:9942-9947.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9942-9947
-
-
Yang, D.1
Buchholz, F.2
Huang, Z.3
Goga, A.4
Chen, C.Y.5
Brodsky, F.M.6
Bishop, J.M.7
-
11
-
-
0037335550
-
Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing
-
Myers, J.W., J.T. Jones, T. Meyer, and J.E. Ferrell, Jr. 2003. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat. Biotechnol. 21:324-328.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 324-328
-
-
Myers, J.W.1
Jones, J.T.2
Meyer, T.3
Ferrell Jr., J.E.4
-
12
-
-
19944367565
-
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
-
Kittler, R., G. Putz, L. Pelletier, I. Poser, A.K. Heninger, D. Drechsel, S. Fischer, I. Konstantinova, et al. 2004. An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature 432:1036-1040.
-
(2004)
Nature
, vol.432
, pp. 1036-1040
-
-
Kittler, R.1
Putz, G.2
Pelletier, L.3
Poser, I.4
Heninger, A.K.5
Drechsel, D.6
Fischer, S.7
Konstantinova, I.8
-
13
-
-
0347089019
-
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
-
Zheng, L., J. Liu, S. Batalov, D. Zhou, A. Orth, S. Ding, and P.G. Schultz. 2004. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA 101:135-140.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 135-140
-
-
Zheng, L.1
Liu, J.2
Batalov, S.3
Zhou, D.4
Orth, A.5
Ding, S.6
Schultz, P.G.7
-
14
-
-
0043238703
-
Gene silencing in mammalian cells by PCR-based short hairpin RNA
-
Gou, D., N. Jin, and L. Liu. 2003. Gene silencing in mammalian cells by PCR-based short hairpin RNA. FEBS Lett. 548:113-118.
-
(2003)
FEBS Lett.
, vol.548
, pp. 113-118
-
-
Gou, D.1
Jin, N.2
Liu, L.3
-
15
-
-
0036847965
-
Functional siRNA expression from transfected PCR products
-
Castanotto, D., H. Li, and J.J. Rossi. 2002. Functional siRNA expression from transfected PCR products. RNA 8:1454-1460.
-
(2002)
RNA
, vol.8
, pp. 1454-1460
-
-
Castanotto, D.1
Li, H.2
Rossi, J.J.3
-
16
-
-
20844438492
-
Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis
-
Cleary, M.A., K. Kilian, Y. Wang, J. Bradshaw, G. Cavet, W. Ge, A. Kulkarni, P.J. Paddison, et al. 2004. Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis. Nat. Methods 1:241-248.
-
(2004)
Nat. Methods
, vol.1
, pp. 241-248
-
-
Cleary, M.A.1
Kilian, K.2
Wang, Y.3
Bradshaw, J.4
Cavet, G.5
Ge, W.6
Kulkarni, A.7
Paddison, P.J.8
-
17
-
-
0842310832
-
Restriction enzyme-generated siRNA (REGS) vectors and libraries
-
Sen, G., T.S. Wehrman, J.W. Myers, and H.M. Blau. 2004. Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat. Genet. 36:183-189.
-
(2004)
Nat. Genet.
, vol.36
, pp. 183-189
-
-
Sen, G.1
Wehrman, T.S.2
Myers, J.W.3
Blau, H.M.4
-
18
-
-
0842332405
-
Enzymatic production of RNAi libraries from cDNAs
-
Shirane, D., K. Sugao, S. Namiki, M. Tanabe, M. Iino, and K. Hirose. 2004. Enzymatic production of RNAi libraries from cDNAs. Nat. Genet. 36:190-196.
-
(2004)
Nat. Genet.
, vol.36
, pp. 190-196
-
-
Shirane, D.1
Sugao, K.2
Namiki, S.3
Tanabe, M.4
Iino, M.5
Hirose, K.6
-
19
-
-
1842631431
-
Small interfering RNA production by enzymatic engineering of DNA (SPEED)
-
Luo, B., A.D. Heard, and H.F. Lodish. 2004. Small interfering RNA production by enzymatic engineering of DNA (SPEED). Proc. Natl. Acad. Sci. USA 101:5494-5499.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5494-5499
-
-
Luo, B.1
Heard, A.D.2
Lodish, H.F.3
-
20
-
-
0142259345
-
New tools for functional mammalian cancer genetics
-
Brummelkamp, T.R. and R. Bernards. 2003. New tools for functional mammalian cancer genetics. Nat. Rev. Cancer 3:781-789.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 781-789
-
-
Brummelkamp, T.R.1
Bernards, R.2
-
21
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
Berns, K., E.M. Hijmans, J. Mullenders, T.R. Brummelkamp, A. Velds, M. Heimerikx, R.M. Kerkhoven, M. Madiredjo, et al. 2004. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428:431-437.
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
Berns, K.1
Hijmans, E.M.2
Mullenders, J.3
Brummelkamp, T.R.4
Velds, A.5
Heimerikx, M.6
Kerkhoven, R.M.7
Madiredjo, M.8
-
22
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
Paddison, P.J., J.M. Silva, D.S. Conklin, M. Schlabach, M. Li, S. Aruleba, V. Balija, A. O'Shaughnessy, L. Gnoj, et al. 2004. A resource for large-scale RNA-interference-based screens in mammals. Nature 428:427-431.
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
Paddison, P.J.1
Silva, J.M.2
Conklin, D.S.3
Schlabach, M.4
Li, M.5
Aruleba, S.6
Balija, V.7
O'Shaughnessy, A.8
Gnoj, L.9
-
23
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir, S.M., J. Harborth, K. Weber, and T. Tuschl. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
24
-
-
0037111232
-
Small interfering RNA-mediated gene silencing in T lymphocytes
-
McManus, M.T., B.B. Haines, C.P. Dillon, C.E. Whitehurst, L. van Parijs, J. Chen, and P.A. Sharp. 2002. Small interfering RNA-mediated gene silencing in T lymphocytes. J. Immunol. 169:5754-5760.
-
(2002)
J. Immunol.
, vol.169
, pp. 5754-5760
-
-
McManus, M.T.1
Haines, B.B.2
Dillon, C.P.3
Whitehurst, C.E.4
Van Parijs, L.5
Chen, J.6
Sharp, P.A.7
-
25
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova, A., A. Reynolds, and S.D. Jayasena. 2003. Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
26
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz, D.S., G. Hutvagner, T. Du, Z. Xu, N. Aronin, and P.D. Zamore. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
27
-
-
0141750434
-
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
-
Aza-Blanc, P., C.L. Cooper, K. Wagner, S. Batalov, Q.L. Deveraux, and M.P. Cooke. 2003. Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol. Cell 12:627-637.
-
(2003)
Mol. Cell
, vol.12
, pp. 627-637
-
-
Aza-Blanc, P.1
Cooper, C.L.2
Wagner, K.3
Batalov, S.4
Deveraux, Q.L.5
Cooke, M.P.6
-
28
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds, A., D. Leake, Q. Boese, S. Scaringe, W.S. Marshall, and A. Khvorova. 2004. Rational siRNA design for RNA interference. Nat. Biotechnol. 22:326-330.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
29
-
-
26444437334
-
siRNA target site secondary structure predictions using local stable substructures
-
Heale, B.S., H.S. Soifer, C. Bowers, and J.J. Rossi. 2005. siRNA target site secondary structure predictions using local stable substructures. Nucleic Acids Res. 33:e30.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Heale, B.S.1
Soifer, H.S.2
Bowers, C.3
Rossi, J.J.4
-
30
-
-
3242877996
-
Sfold web server for statistical folding and rational design of nucleic acids
-
Ding, Y., C.Y. Chan, and C.E. Lawrence. 2004. Sfold web server for statistical folding and rational design of nucleic acids. Nucleic Acids Res. 32:W135-W141.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Ding, Y.1
Chan, C.Y.2
Lawrence, C.E.3
-
31
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas, D., C. Lerner, J. Burchard, W. Ge, P.S. Linsley, P.J. Paddison, G.J. Hannon, and M.A. Cleary. 2005. Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 25:227-231.
-
(2005)
Nat. Biotechnol.
, vol.25
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
Ge, W.4
Linsley, P.S.5
Paddison, P.J.6
Hannon, G.J.7
Cleary, M.A.8
-
32
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
Kim, D.H., M.A. Behlke, S.D. Rose, M.S. Chang, S. Choi, and J.J. Rossi. 2005. Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat. Biotechnol. 23:222-226.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
33
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson, A.L., S.R. Bartz, J. Schelter, S.V. Kobayashi, J. Burchard, M. Mao, B. Li, G. Cavet, and P.S. Linsley. 2003. Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21:635-637.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
34
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
Hemann, M.T., J.S. Fridman, J.T. Zilfou, E. Hernando, P.J. Paddison, C. Cordon-Cardo, G.J. Hannon, and S.W. Lowe. 2003. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat. Genet. 33:396-400.
-
(2003)
Nat. Genet.
, vol.33
, pp. 396-400
-
-
Hemann, M.T.1
Fridman, J.S.2
Zilfou, J.T.3
Hernando, E.4
Paddison, P.J.5
Cordon-Cardo, C.6
Hannon, G.J.7
Lowe, S.W.8
-
35
-
-
0142092529
-
High-throughput selection of effective RNAi probes for gene silencing
-
Kumar, R., D.S. Conklin, and V. Mittal. 2003. High-throughput selection of effective RNAi probes for gene silencing. Genome Res. 13:2333-2340.
-
(2003)
Genome Res.
, vol.13
, pp. 2333-2340
-
-
Kumar, R.1
Conklin, D.S.2
Mittal, V.3
-
36
-
-
0030005755
-
The I.M.A.G.E. Consortium: An integrated molecular analysis of genomes and their expression
-
Lennon, G., C. Auffray, M. Polymeropoulos, and M.B. Soares. 1996. The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. Genomics 33:151-152.
-
(1996)
Genomics
, vol.33
, pp. 151-152
-
-
Lennon, G.1
Auffray, C.2
Polymeropoulos, M.3
Soares, M.B.4
-
37
-
-
0347089037
-
Electroporation and RNA interference in the rodent retina in vivo and in vitro
-
Matsuda, T. and C.L. Cepko. 2004. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc. Natl. Acad. Sci. USA 101:16-22.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16-22
-
-
Matsuda, T.1
Cepko, C.L.2
-
38
-
-
0346216853
-
Local gene knockdown in the brain using viral-mediated RNA interference
-
Hommel, J.D., R.M. Sears, D. Georgescu, D.L. Simmons, and R.J. DiLeone. 2003. Local gene knockdown in the brain using viral-mediated RNA interference. Nat. Med. 9:1539-1544.
-
(2003)
Nat. Med.
, vol.9
, pp. 1539-1544
-
-
Hommel, J.D.1
Sears, R.M.2
Georgescu, D.3
Simmons, D.L.4
Dileone, R.J.5
-
39
-
-
0036787671
-
siRNA-mediated gene silencing in vitro and in vivo
-
Xia, H., Q. Mao, H.L. Paulson, and B.L. Davidson. 2002. siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 20:1006-1010.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1006-1010
-
-
Xia, H.1
Mao, Q.2
Paulson, H.L.3
Davidson, B.L.4
-
40
-
-
1942494048
-
Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA
-
Kishida, T., H. Asada, S. Gojo, S. Ohashi, M. Shin-Ya, K. Yasutomi, R. Terauchi, K.A. Takahashi, et al. 2004. Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA. J. Gene Med. 6:105-110.
-
(2004)
J. Gene Med.
, vol.6
, pp. 105-110
-
-
Kishida, T.1
Asada, H.2
Gojo, S.3
Ohashi, S.4
Shin-Ya, M.5
Yasutomi, K.6
Terauchi, R.7
Takahashi, K.A.8
-
41
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis, D.L., J.E. Hagstrom, A.G. Loomis, J.A. Wolff, and H. Herweijer. 2002. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32:107-108.
-
(2002)
Nat. Genet.
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
42
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song, E., S.K. Lee, J. Wang, N. Ince, N. Ouyang, J. Min, J. Chen, P. Shankar, and J. Lieberman. 2003. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 9:347-351.
-
(2003)
Nat. Med.
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
Ince, N.4
Ouyang, N.5
Min, J.6
Chen, J.7
Shankar, P.8
Lieberman, J.9
-
43
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey, A.P., H. Nakai, K. Pandey, Z. Huang, F.H. Salazar, H. Xu, S.F. Wieland, P.L. Marion, and M.A. Kay. 2003. Inhibition of hepatitis B virus in mice by RNA interference. Nat. Biotechnol. 21:639-644.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
Huang, Z.4
Salazar, F.H.5
Xu, H.6
Wieland, S.F.7
Marion, P.L.8
Kay, M.A.9
-
44
-
-
11844251207
-
RNA interference in vivo: Toward synthetic small inhibitory RNA-based therapeutics
-
de Fougerolles, A., M. Manoharan, R. Meyers, and H.P. Vornlocher. 2005. RNA interference in vivo: toward synthetic small inhibitory RNA-based therapeutics. Methods Enzymol. 392:278-296.
-
(2005)
Methods Enzymol.
, vol.392
, pp. 278-296
-
-
De Fougerolles, A.1
Manoharan, M.2
Meyers, R.3
Vornlocher, H.P.4
-
45
-
-
15544377122
-
RNAi as an experimental and therapeutic tool to study and regulate physiological and disease processes
-
Dillon, C.P., P. Sandy, A. Nencioni, S. Kissler, D.A. Rubinson, and L. Van Parijs. 2005. RNAi as an experimental and therapeutic tool to study and regulate physiological and disease processes. Annu. Rev. Physiol. 67:147-173.
-
(2005)
Annu. Rev. Physiol.
, vol.67
, pp. 147-173
-
-
Dillon, C.P.1
Sandy, P.2
Nencioni, A.3
Kissler, S.4
Rubinson, D.A.5
Van Parijs, L.6
-
46
-
-
3242677639
-
siRNAs: Applications in functional genomics and potential as therapeutics
-
Dorsett, Y. and T. Tuschl. 2004. siRNAs: applications in functional genomics and potential as therapeutics. Nat. Rev. Drug Discov. 3:318-329.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
47
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
Czauderna, F., M. Fechtner, S. Dames, H. Aygun, A. Klippel, G.J. Pronk, K. Giese, and J. Kaufmann. 2003. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. 31:2705-2716.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
Aygun, H.4
Klippel, A.5
Pronk, G.J.6
Giese, K.7
Kaufmann, J.8
-
48
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
Braasch, D.A., S. Jensen, Y. Liu, K. Kaur, K. Arar, M.A. White, and D.R. Corey. 2003. RNA interference in mammalian cells by chemically-modified RNA. Biochemistry 42:7967-7975.
-
(2003)
Biochemistry
, vol.42
, pp. 7967-7975
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
Kaur, K.4
Arar, K.5
White, M.A.6
Corey, D.R.7
-
49
-
-
0037440005
-
Tolerance for mutations and chemical modifications in a siRNA
-
Amarzguioui, M., T. Holen, E. Babaie, and H. Prydz. 2003. Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res. 31:589-595.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 589-595
-
-
Amarzguioui, M.1
Holen, T.2
Babaie, E.3
Prydz, H.4
-
50
-
-
0036752785
-
RNAi in human cells: Basic structural and functional features of small interfering RNA
-
Chiu, Y.L. and T.M. Rana. 2002. RNAi in human cells: basic structural and functional features of small interfering RNA. Mol. Cell 70:549-561.
-
(2002)
Mol. Cell
, vol.70
, pp. 549-561
-
-
Chiu, Y.L.1
Rana, T.M.2
-
51
-
-
0041331496
-
siRNA function in RNAi: A chemical modification analysis
-
Chiu, Y.L. and T.M. Rana. 2003. siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-1048.
-
(2003)
RNA
, vol.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
Rana, T.M.2
-
52
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek, J., A. Akinc, B. Bramlage, K. Charisse, R. Constien, M. Donoghue, S. Elbashir, A. Geick, P. Hadwiger, et al. 2004. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432:173-178.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Geick, A.8
Hadwiger, P.9
-
53
-
-
3142708570
-
Cre-lox-regulated conditional RNA interference from transgenes
-
Ventura, A., A. Meissner, C.P. Dillon, M. McManus, P.A. Sharp, L. Van Parijs, R. Jaenisch, and T. Jacks. 2004. Cre-lox-regulated conditional RNA interference from transgenes. Proc. Natl. Acad. Sci. USA 101:10380-10385.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
McManus, M.4
Sharp, P.A.5
Van Parijs, L.6
Jaenisch, R.7
Jacks, T.8
-
54
-
-
0038708339
-
Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
-
Kunath, T., G. Gish, H. Lickert, N. Jones, T. Pawson, and J. Rossant. 2003. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat. Biotechnol. 21:559-561.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 559-561
-
-
Kunath, T.1
Gish, G.2
Lickert, H.3
Jones, N.4
Pawson, T.5
Rossant, J.6
-
55
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
Hasuwa, H., K. Kaseda, T. Einarsdottir, and M. Okabe. 2002. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532:227-230.
-
(2002)
FEBS Lett.
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
56
-
-
0037948173
-
Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter
-
Shinagawa, T. and S. Ishii. 2003. Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter. Genes Dev. 17:1340-1345.
-
(2003)
Genes Dev.
, vol.17
, pp. 1340-1345
-
-
Shinagawa, T.1
Ishii, S.2
-
57
-
-
0037377201
-
Transgenic RNAi in mouse oocytes: A simple and fast approach to study gene function
-
Stein, P., P. Svoboda, and R.M. Schultz. 2003. Transgenic RNAi in mouse oocytes: a simple and fast approach to study gene function. Dev. Biol. 256:187-193.
-
(2003)
Dev. Biol.
, vol.256
, pp. 187-193
-
-
Stein, P.1
Svoboda, P.2
Schultz, R.M.3
-
58
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson, D.A., C.P. Dillon, A.V. Kwiatkowski, C. Sievers, L. Yang, J. Kopinja, D.L. Rooney, M.M. Ihrig, et al. 2003. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33:401-406.
-
(2003)
Nat. Genet.
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
Sievers, C.4
Yang, L.5
Kopinja, J.6
Rooney, D.L.7
Ihrig, M.M.8
-
59
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
Tiscornia, G., O. Singer, M. Ikawa, and I.M. Verma. 2003. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA 100:1844-1848.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
60
-
-
0642303887
-
Inducible shRNA expression for application in a prostate cancer mouse model
-
Czauderna, F., A. Santel, M. Hinz, M. Fechtner, B. Durieux, G. Fisch, F. Leenders, W. Arnold, et al. 2003. Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res. 31:e127.
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Czauderna, F.1
Santel, A.2
Hinz, M.3
Fechtner, M.4
Durieux, B.5
Fisch, G.6
Leenders, F.7
Arnold, W.8
-
61
-
-
0042941765
-
Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
-
Chen, Y., G. Stamatoyannopoulos, and C.Z. Song. 2003. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res. 63:4801-4804.
-
(2003)
Cancer Res.
, vol.63
, pp. 4801-4804
-
-
Chen, Y.1
Stamatoyannopoulos, G.2
Song, C.Z.3
-
62
-
-
10744219596
-
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
-
van de Wetering, M., I. Oving, V. Muncan, M.T. Pon Fong, H. Brantjes, D. van Leenen, F.C. Holstege, T.R. Brummelkamp, et al. 2003. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep. 4:609-615.
-
(2003)
EMBO Rep.
, vol.4
, pp. 609-615
-
-
Van De Wetering, M.1
Oving, I.2
Muncan, V.3
Pon Fong, M.T.4
Brantjes, H.5
Van Leenen, D.6
Holstege, F.C.7
Brummelkamp, T.R.8
-
63
-
-
0042662862
-
Establishment of conditional vectors for hairpin siRNA knockdowns
-
Matsukura, S., P.A. Jones, and D. Takai. 2003. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Re. 31:e77.
-
(2003)
Nucleic Acids Re.
, vol.31
-
-
Matsukura, S.1
Jones, P.A.2
Takai, D.3
-
64
-
-
0043210428
-
Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
-
Wiznerowicz, M. and D. Trono. 2003. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77:8957-8961.
-
(2003)
J. Virol.
, vol.77
, pp. 8957-8961
-
-
Wiznerowicz, M.1
Trono, D.2
-
65
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
Gupta, S., R.A. Schoer, J.E. Egan, G.J. Hannon, and V. Mittal. 2004. Inducible, reversible, and stable RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 101:1927-1932.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
66
-
-
3042545272
-
Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity
-
Higuchi, M., R. Tsutsumi, H. Higashi, and M. Hatakeyama. 2004. Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity. Cancer Sci. 95:442-447.
-
(2004)
Cancer Sci.
, vol.95
, pp. 442-447
-
-
Higuchi, M.1
Tsutsumi, R.2
Higashi, H.3
Hatakeyama, M.4
-
67
-
-
2442584612
-
CRE recombinase-inducible RNA interference mediated by lentiviral vectors
-
Tiscornia, G., V. Tergaonkar, F. Galimi, and I.M. Verma. 2004. CRE recombinase-inducible RNA interference mediated by lentiviral vectors. Proc. Natl. Acad. Sci. USA 101:7347-7351.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7347-7351
-
-
Tiscornia, G.1
Tergaonkar, V.2
Galimi, F.3
Verma, I.M.4
-
68
-
-
2342627912
-
Control of siRNA expression using the Cre-loxP recombination system
-
Kasim, V., M. Miyagishi, and K. Taira. 2004. Control of siRNA expression using the Cre-loxP recombination system. Nucleic Acids Res. 32:e66.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Kasim, V.1
Miyagishi, M.2
Taira, K.3
-
69
-
-
18144453718
-
Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system
-
Coumoul, X., W. Li, R.H. Wang, and C. Deng. 2004. Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system. Nucleic Acids Res. 32:e85.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Coumoul, X.1
Li, W.2
Wang, R.H.3
Deng, C.4
-
70
-
-
1642487123
-
Conditional gene knock-down by CRE-dependent short interfering RNAs
-
Fritsch, L., L.A. Martinez, R. Sekhri, I. Naguibneva, M. Gerard, M. Vandromme, L. Schaeffer, and A. Harel-Bellan. 2004. Conditional gene knock-down by CRE-dependent short interfering RNAs. EMBO Rep. 5:178-182.
-
(2004)
EMBO Rep.
, vol.5
, pp. 178-182
-
-
Fritsch, L.1
Martinez, L.A.2
Sekhri, R.3
Naguibneva, I.4
Gerard, M.5
Vandromme, M.6
Schaeffer, L.7
Harel-Bellan, A.8
|