-
1
-
-
0018344553
-
Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
-
Barnes C.A. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol. 93:1979;74-104.
-
(1979)
J Comp Physiol Psychol
, vol.93
, pp. 74-104
-
-
Barnes, C.A.1
-
2
-
-
0024420493
-
Selective improvement of aged rat short-term spatial memory by 3,4-diaminopyridine
-
Barnes C.A., Eppich C., Rao G. Selective improvement of aged rat short-term spatial memory by 3,4-diaminopyridine. Neurobiol Aging. 10:1989;37-341.
-
(1989)
Neurobiol Aging
, vol.10
, pp. 37-341
-
-
Barnes, C.A.1
Eppich, C.2
Rao, G.3
-
3
-
-
0025194861
-
Acetyl-1-carnitine 2: Effects on learning and memory performance of aged rats in simple and complex mazes
-
Barnes C.A., Markowska A.L., Ingram D.K., Kametani H., Spangler E.L., Lemken V.J., Olton D.S. Acetyl-1-carnitine 2: effects on learning and memory performance of aged rats in simple and complex mazes. Neurobiol Aging. 11:1990;499-506.
-
(1990)
Neurobiol Aging
, vol.11
, pp. 499-506
-
-
Barnes, C.A.1
Markowska, A.L.2
Ingram, D.K.3
Kametani, H.4
Spangler, E.L.5
Lemken, V.J.6
Olton, D.S.7
-
4
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D.R., Ratovitski T., van Lare J., Lee M.K., Gonzales V., Jenkins N.A., Copeland N.G., Price D.L., Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19:1997;939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
5
-
-
0009703087
-
Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies
-
Crawley J.N., Belknap J.K., Collins A., Crabbe J.C., Frankel W., Henderson N., Hitzemann R.J., Maxson S.C., Miner L.L., Silva A.J., Wehner J.M., Wynshaw-Boris A., Paylor R. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology. 132:1997;107-124.
-
(1997)
Psychopharmacology
, vol.132
, pp. 107-124
-
-
Crawley, J.N.1
Belknap, J.K.2
Collins, A.3
Crabbe, J.C.4
Frankel, W.5
Henderson, N.6
Hitzemann, R.J.7
Maxson, S.C.8
Miner, L.L.9
Silva, A.J.10
Wehner, J.M.11
Wynshaw-Boris, A.12
Paylor, R.13
-
6
-
-
0342506436
-
Proteolytical processing of mutated human amyloid precursor protein in transgenic mice
-
Czech C., Delaere P., Macq A.F., Reibaud M., Dreisler S., Touchet N., Schombert B., Mazadier M., Mercken L., Theisen M., Pradier L., Octave J.-N., Beyreuther K., Tremp G. Proteolytical processing of mutated human amyloid precursor protein in transgenic mice. Mol Neurobiol. 47:1997;108-116.
-
(1997)
Mol Neurobiol
, vol.47
, pp. 108-116
-
-
Czech, C.1
Delaere, P.2
Macq, A.F.3
Reibaud, M.4
Dreisler, S.5
Touchet, N.6
Schombert, B.7
Mazadier, M.8
Mercken, L.9
Theisen, M.10
Pradier, L.11
Octave, J.-N.12
Beyreuther, K.13
Tremp, G.14
-
7
-
-
0028363247
-
A behavioural analysis of rats with damage to the medial prefrontal cortex using the Morris water maze: Evidence for behavioral flexibility, but not for impaired spatial navigation
-
de Bruin J.P., Sanchez-Santed F., Heinsbroek R.P., Donker A., Postmes P. A behavioural analysis of rats with damage to the medial prefrontal cortex using the Morris water maze: evidence for behavioral flexibility, but not for impaired spatial navigation. Brain Res. 652:1994;323-333.
-
(1994)
Brain Res
, vol.652
, pp. 323-333
-
-
De Bruin, J.P.1
Sanchez-Santed, F.2
Heinsbroek, R.P.3
Donker, A.4
Postmes, P.5
-
8
-
-
0027410176
-
Beta A4 deposits are constant in the brains of the oldest old: An immunocytochemical study of 20 French centenarians
-
DeLaere P., He Y., Fayet G., Duychaerts C., Hauw J.J. Beta A4 deposits are constant in the brains of the oldest old: an immunocytochemical study of 20 French centenarians. Neurobiol Aging. 14:1993;191-194.
-
(1993)
Neurobiol Aging
, vol.14
, pp. 191-194
-
-
DeLaere, P.1
He, Y.2
Fayet, G.3
Duychaerts, C.4
Hauw, J.J.5
-
9
-
-
0029801980
-
Spatial learning deficit in mice expressing human 751-amino acid β-amyloid precursor protein
-
D'Hooge R., Nagels G., Westland C.E., Mucke L., De Deyn P.P. Spatial learning deficit in mice expressing human 751-amino acid β-amyloid precursor protein. NeuroReport. 7:1996;2807-2811.
-
(1996)
NeuroReport
, vol.7
, pp. 2807-2811
-
-
D'Hooge, R.1
Nagels, G.2
Westland, C.E.3
Mucke, L.4
De Deyn, P.P.5
-
11
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F., Guido T., Hagopian S., Johnson-Wood K., Khan K., Lee M., Leibowitz P., Lieberburg I., Little S., Masliah E., McConlogue L., Montoya-Zavala M., Mucke L., Paganini L., Penniman E., Power M., Schenk D., Seubert P., Snyder B., Soriano F., Tan H., Vitale J., Wadsworth S., Wolozin B., Zhao J. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature. 373:1995;523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seubert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
12
-
-
0029940557
-
Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
-
Gerlai R. Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci. 19:1996;177-181.
-
(1996)
Trends Neurosci
, vol.19
, pp. 177-181
-
-
Gerlai, R.1
-
13
-
-
0029064572
-
Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for β-APP751
-
Higgins L.S., Rodems J.M., Catalano R., Quon D., Cordell B. Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for β-APP751. Proc Natl Acad Sci USA. 92:1995;4402-4406.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4402-4406
-
-
Higgins, L.S.1
Rodems, J.M.2
Catalano, R.3
Quon, D.4
Cordell, B.5
-
14
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L., Gordon M.N., McGowan E., Yu X., Benkovic S., Jantzen P., Wright K., Saad I., Mueller R., Morgan D., Sanders S., Zehr C., O'Campo K., Hardy J., Prada C., Eckman C., Younkin S., Hsiao K., Duff K. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med. 4:1998;97-100.
-
(1998)
Nat Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
15
-
-
0028810244
-
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
-
Hsiao K., Borchelt D.R., Olson K., Johannsdottir R., Kitt C., Yunis W., Xu S., Eckman C., Younkin S., Price D., Iadecola C., Clark H.B., Carlson G. Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron. 15:1995;1203-1218.
-
(1995)
Neuron
, vol.15
, pp. 1203-1218
-
-
Hsiao, K.1
Borchelt, D.R.2
Olson, K.3
Johannsdottir, R.4
Kitt, C.5
Yunis, W.6
Xu, S.7
Eckman, C.8
Younkin, S.9
Price, D.10
Iadecola, C.11
Clark, H.B.12
Carlson, G.13
-
16
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
17
-
-
0030612033
-
APPSW transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1
-
Irizarry M.C., McNamara M., Fedorchak K., Hsaio K., Hyman B.T. APPSW transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1. J Neuropathol Exp Neurol. 56:1997;965-973.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 965-973
-
-
Irizarry, M.C.1
McNamara, M.2
Fedorchak, K.3
Hsaio, K.4
Hyman, B.T.5
-
18
-
-
0030611097
-
Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse
-
Irizarry M.C., Soriano F., McNamara M., Page K.J., Schenk D., Games D., Hyman B.T. Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J Neurosci. 17:1997;7053-7059.
-
(1997)
J Neurosci
, vol.17
, pp. 7053-7059
-
-
Irizarry, M.C.1
Soriano, F.2
McNamara, M.3
Page, K.J.4
Schenk, D.5
Games, D.6
Hyman, B.T.7
-
19
-
-
0014548982
-
Differential effects of hippocampal lesions upon sequential tasks and maze learning by the rat
-
Jackson W.J., Strong P.N. Differential effects of hippocampal lesions upon sequential tasks and maze learning by the rat. J Comp Physiol Psychol. 68:1969;442-450.
-
(1969)
J Comp Physiol Psychol
, vol.68
, pp. 442-450
-
-
Jackson, W.J.1
Strong, P.N.2
-
20
-
-
0031020909
-
42 deposition in a transgenic mouse model of Alzheimer disease
-
42 deposition in a transgenic mouse model of Alzheimer disease. Proc Natl Acad Sci USA. 94:1997;1550-1555.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1550-1555
-
-
Johnson-Wood, K.1
Lee, M.2
Motter, R.3
Hu, K.4
Gordon, G.5
Barbour, R.6
Khan, K.7
Gordon, M.8
Tan, H.9
Games, D.10
Lieberburg, I.11
Schenk, D.12
Seubert, P.13
McConlogue, L.14
-
21
-
-
0030011889
-
Mice, gene targeting and behaviour: More than just genetic background
-
Lathe R. Mice, gene targeting and behaviour: more than just genetic background. Trends Neurosci. 19:1996;183-186.
-
(1996)
Trends Neurosci
, vol.19
, pp. 183-186
-
-
Lathe, R.1
-
22
-
-
0030921483
-
Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task
-
Lindner M.D., Plone M.A., Schallert T., Emerich D.F. Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task. Brain Res Cogn Brain Res. 5:1997;329-333.
-
(1997)
Brain Res Cogn Brain Res
, vol.5
, pp. 329-333
-
-
Lindner, M.D.1
Plone, M.A.2
Schallert, T.3
Emerich, D.F.4
-
23
-
-
0029954289
-
Lack of β-amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations
-
Malherbe P., Richards J.G., Martin J.R., Bluethmann H., Maggio J., Huber G. Lack of β-amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations. Neurobiol Aging. 17:1996;205-214.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 205-214
-
-
Malherbe, P.1
Richards, J.G.2
Martin, J.R.3
Bluethmann, H.4
Maggio, J.5
Huber, G.6
-
24
-
-
0029055738
-
Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein
-
Moran P.M., Higgins L.S., Cordell B., Moser P.C. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein. Proc Natl Acad Sci USA. 92:1995;5341-5345.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5341-5345
-
-
Moran, P.M.1
Higgins, L.S.2
Cordell, B.3
Moser, P.C.4
-
25
-
-
0026907151
-
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
-
Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat Genet. 1:1992;345-347.
-
(1992)
Nat Genet
, vol.1
, pp. 345-347
-
-
Mullan, M.1
Crawford, F.2
Axelman, K.3
Houlden, H.4
Lilius, L.5
Winblad, B.6
Lannfelt, L.7
-
26
-
-
0030978998
-
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
-
Nalbantaglu J., Tirado-Santiago G., Lahsaini A., Poirier J., Goncalves O., Verge G., Momoli F., Weiner S.A., Massicotte G., Jullen J.-P., Shapiro M.L. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature. 387:1997;500-505.
-
(1997)
Nature
, vol.387
, pp. 500-505
-
-
Nalbantaglu, J.1
Tirado-Santiago, G.2
Lahsaini, A.3
Poirier, J.4
Goncalves, O.5
Verge, G.6
Momoli, F.7
Weiner, S.A.8
Massicotte, G.9
Jullen, J.-P.10
Shapiro, M.L.11
-
27
-
-
0031944692
-
Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: A chronic oxidative paradigm for testing antioxidant therapies in vivo
-
Pappolla M.A., Chyan Y.J., Omar R.A., Hsiao K., Perry G., Smith M.A., Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol. 152:1998;871-877.
-
(1998)
Am J Pathol
, vol.152
, pp. 871-877
-
-
Pappolla, M.A.1
Chyan, Y.J.2
Omar, R.A.3
Hsiao, K.4
Perry, G.5
Smith, M.A.6
Bozner, P.7
-
28
-
-
0033082456
-
SW transgenic mouse model for Alzheimer's disease.
-
SW transgenic mouse model for Alzheimer's disease. J Neurosci Methods, 1998;87:87-95.
-
(1998)
J Neurosci Methods
, vol.87
, pp. 87-95
-
-
Pompl, P.1
-
29
-
-
0002451152
-
The PDAPP transgenic mouse as an animal model for Aβ-induced amyloidosis and neuropathology
-
Schenk D., Masliah E., Lee M., Johnson-Wood K., Seubert P., Games D. The PDAPP transgenic mouse as an animal model for Aβ-induced amyloidosis and neuropathology. Alzheimer's Dis Rev. 2:1997;20-27.
-
(1997)
Alzheimer's Dis Rev
, vol.2
, pp. 20-27
-
-
Schenk, D.1
Masliah, E.2
Lee, M.3
Johnson-Wood, K.4
Seubert, P.5
Games, D.6
-
30
-
-
0031981072
-
Amyloid-β deposition in Alzheimer transgenic mice is associated with oxidative stress
-
Smith M.A., Hirai K., Hsiao K., Pappolla M.A., Harris P.L., Siedlak S.L., Tabaton M., Perry G. Amyloid-β deposition in Alzheimer transgenic mice is associated with oxidative stress. J Neurochem. 70:1998;2212-2215.
-
(1998)
J Neurochem
, vol.70
, pp. 2212-2215
-
-
Smith, M.A.1
Hirai, K.2
Hsiao, K.3
Pappolla, M.A.4
Harris, P.L.5
Siedlak, S.L.6
Tabaton, M.7
Perry, G.8
-
31
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K.H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P.A., Waridel C., Calhoun M.E., Jucker M., Probst A., Staufenbiel M., Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci USA. 94:1997;13287-13292.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
32
-
-
0026320841
-
Transgenic mice for the amyloid precursor protein 695 isoform have impaired spatial memory
-
Yamaguchi F., Richards S., Beyreuther K., Salbaum M., Carlson G.A., Dunnett S.B. Transgenic mice for the amyloid precursor protein 695 isoform have impaired spatial memory. NeuroReport. 2:1991;781-784.
-
(1991)
NeuroReport
, vol.2
, pp. 781-784
-
-
Yamaguchi, F.1
Richards, S.2
Beyreuther, K.3
Salbaum, M.4
Carlson, G.A.5
Dunnett, S.B.6
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